Type |
Details |
Score |
Publication |
First Author: |
Burton VJ |
Year: |
2011 |
Journal: |
Blood |
Title: |
Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function. |
Volume: |
117 |
Issue: |
1 |
Pages: |
333-41 |
|
•
•
•
•
•
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Publication |
First Author: |
Rothman AM |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension. |
Volume: |
126 |
Issue: |
7 |
Pages: |
2495-508 |
|
•
•
•
•
•
|
Publication |
First Author: |
West JD |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. |
Volume: |
11 |
Issue: |
2 |
Pages: |
e0148657 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson JA |
Year: |
2012 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension. |
Volume: |
302 |
Issue: |
5 |
Pages: |
L474-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brittain EL |
Year: |
2016 |
Journal: |
Circulation |
Title: |
Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension. |
Volume: |
133 |
Issue: |
20 |
Pages: |
1936-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2016 |
Journal: |
Circulation |
Title: |
Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism. |
Volume: |
133 |
Issue: |
1 |
Pages: |
82-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee MH |
Year: |
2022 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension. |
Volume: |
323 |
Issue: |
3 |
Pages: |
L355-L371 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling. |
Volume: |
7 |
Issue: |
37 |
Pages: |
58848-58861 |
|
•
•
•
•
•
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Publication |
First Author: |
Toyama T |
Year: |
2023 |
Journal: |
Sci Rep |
Title: |
GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension. |
Volume: |
13 |
Issue: |
1 |
Pages: |
6593 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghatnekar A |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension. |
Volume: |
182 |
Issue: |
6 |
Pages: |
2391-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rätsep MT |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency. |
Volume: |
315 |
Issue: |
6 |
Pages: |
L977-L990 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi X |
Year: |
2024 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase promotes pulmonary arterial smooth muscle cell proliferation via the Ras signaling pathway. |
Volume: |
327 |
Issue: |
4 |
Pages: |
C901-C912 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samokhin AO |
Year: |
2018 |
Journal: |
Sci Transl Med |
Title: |
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. |
Volume: |
10 |
Issue: |
445 |
|
|
•
•
•
•
•
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Publication |
First Author: |
Talati M |
Year: |
2010 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension. |
Volume: |
299 |
Issue: |
3 |
Pages: |
L363-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
West J |
Year: |
2008 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. |
Volume: |
295 |
Issue: |
5 |
Pages: |
L744-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasuda T |
Year: |
2011 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene. |
Volume: |
301 |
Issue: |
5 |
Pages: |
L667-74 |
|
•
•
•
•
•
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Publication |
First Author: |
Ogo T |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension. |
Volume: |
48 |
Issue: |
6 |
Pages: |
733-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Majka S |
Year: |
2011 |
Journal: |
Respir Res |
Title: |
Physiologic and molecular consequences of endothelial Bmpr2 mutation. |
Volume: |
12 |
|
Pages: |
84 |
|
•
•
•
•
•
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Publication |
First Author: |
Ortiz L |
Year: |
2013 |
Journal: |
Toxicol Lett |
Title: |
In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective. |
Volume: |
223 |
Issue: |
2 |
Pages: |
260-7 |
|
•
•
•
•
•
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Publication |
First Author: |
Nakamura BN |
Year: |
2012 |
Journal: |
Toxicol Sci |
Title: |
Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. |
Volume: |
126 |
Issue: |
1 |
Pages: |
227-41 |
|
•
•
•
•
•
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Publication |
First Author: |
Lu A |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling. |
Volume: |
125 |
Issue: |
3 |
Pages: |
1228-42 |
|
•
•
•
•
•
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Publication |
First Author: |
Murata K |
Year: |
2013 |
Journal: |
Endocrinology |
Title: |
Effect of lactation on postpartum cardiac function of pregnancy-associated hypertensive mice. |
Volume: |
154 |
Issue: |
2 |
Pages: |
597-602 |
|
•
•
•
•
•
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Publication |
First Author: |
Komiya H |
Year: |
2018 |
Journal: |
Sleep |
Title: |
Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice. |
Volume: |
41 |
Issue: |
3 |
|
|
•
•
•
•
•
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Publication |
First Author: |
Takimoto-Ohnishi E |
Year: |
2005 |
Journal: |
Mol Endocrinol |
Title: |
Differential roles of renin and angiotensinogen in the feto-maternal interface in the development of complications of pregnancy. |
Volume: |
19 |
Issue: |
5 |
Pages: |
1361-72 |
|
•
•
•
•
•
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Publication |
First Author: |
Huang Z |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
Defective pulmonary vascular remodeling in Smad8 mutant mice. |
Volume: |
18 |
Issue: |
15 |
Pages: |
2791-801 |
|
•
•
•
•
•
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Publication |
First Author: |
Mondejar-Parreño G |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
HIV transgene expression impairs K+ channel function in the pulmonary vasculature. |
Volume: |
315 |
Issue: |
5 |
Pages: |
L711-L723 |
|
•
•
•
•
•
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Publication |
First Author: |
Boucherat O |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension. |
Volume: |
7 |
Issue: |
1 |
Pages: |
4546 |
|
•
•
•
•
•
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Publication |
First Author: |
Crosby M |
Year: |
2019 |
Journal: |
Drug Metab Dispos |
Title: |
Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice. |
Volume: |
47 |
Issue: |
3 |
Pages: |
279-282 |
|
•
•
•
•
•
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Publication |
First Author: |
Hwangbo C |
Year: |
2017 |
Journal: |
Circulation |
Title: |
Modulation of Endothelial Bone Morphogenetic Protein Receptor Type 2 Activity by Vascular Endothelial Growth Factor Receptor 3 in Pulmonary Arterial Hypertension. |
Volume: |
135 |
Issue: |
23 |
Pages: |
2288-2298 |
|
•
•
•
•
•
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Publication |
First Author: |
Yuan K |
Year: |
2020 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Mural Cell SDF1 Signaling Is Associated with the Pathogenesis of Pulmonary Arterial Hypertension. |
Volume: |
62 |
Issue: |
6 |
Pages: |
747-759 |
|
•
•
•
•
•
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Publication |
First Author: |
Fukai K |
Year: |
2015 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α. |
Volume: |
308 |
Issue: |
8 |
Pages: |
H951-9 |
|
•
•
•
•
•
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Publication |
First Author: |
Qin S |
Year: |
2021 |
Journal: |
Am J Pathol |
Title: |
Up-Regulation of the Long Noncoding RNA X-Inactive-Specific Transcript and the Sex Bias in Pulmonary Arterial Hypertension. |
Volume: |
191 |
Issue: |
6 |
Pages: |
1135-1150 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel M |
Year: |
2017 |
Journal: |
Am J Pathol |
Title: |
Modulation of Intersectin-1s Lung Expression Induces Obliterative Remodeling and Severe Plexiform Arteriopathy in the Murine Pulmonary Vascular Bed. |
Volume: |
187 |
Issue: |
3 |
Pages: |
528-542 |
|
•
•
•
•
•
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Publication |
First Author: |
Lakhal-Littleton S |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice. |
Volume: |
116 |
Issue: |
26 |
Pages: |
13122-13130 |
|
•
•
•
•
•
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Publication |
First Author: |
Steiner MK |
Year: |
2009 |
Journal: |
Circ Res |
Title: |
Interleukin-6 overexpression induces pulmonary hypertension. |
Volume: |
104 |
Issue: |
2 |
Pages: |
236-44, 28p following 244 |
|
•
•
•
•
•
|
Publication |
First Author: |
Russomanno G |
Year: |
2021 |
Journal: |
Mol Ther Nucleic Acids |
Title: |
miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension. |
Volume: |
23 |
|
Pages: |
142-153 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng L |
Year: |
2015 |
Journal: |
Circ Res |
Title: |
MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension. |
Volume: |
117 |
Issue: |
10 |
Pages: |
870-883 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caruso P |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. |
Volume: |
111 |
Issue: |
3 |
Pages: |
290-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Penumatsa KC |
Year: |
2022 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice. |
Volume: |
604 |
|
Pages: |
137-143 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fessel JP |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. |
Volume: |
49 |
Issue: |
5 |
Pages: |
778-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wan F |
Year: |
2016 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension. |
Volume: |
55 |
Issue: |
3 |
Pages: |
337-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guignabert C |
Year: |
2009 |
Journal: |
FASEB J |
Title: |
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22alpha-targeted overexpression of the serotonin transporter. |
Volume: |
23 |
Issue: |
12 |
Pages: |
4135-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chowdhury HM |
Year: |
2019 |
Journal: |
Hum Mol Genet |
Title: |
BMPRII deficiency impairs apoptosis via the BMPRII-ALK1-BclX-mediated pathway in pulmonary arterial hypertension. |
Volume: |
28 |
Issue: |
13 |
Pages: |
2161-2173 |
|
•
•
•
•
•
|
Publication |
First Author: |
Belguise K |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. |
Volume: |
67 |
Issue: |
24 |
Pages: |
11742-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou XL |
Year: |
2021 |
Journal: |
Aging (Albany NY) |
Title: |
SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice. |
Volume: |
13 |
Issue: |
5 |
Pages: |
7538-7548 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu W |
Year: |
2010 |
Journal: |
Blood |
Title: |
The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model. |
Volume: |
116 |
Issue: |
9 |
Pages: |
1613-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Togawa N |
Year: |
2012 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter. |
Volume: |
302 |
Issue: |
11 |
Pages: |
C1652-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Togawa N |
Year: |
2015 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Wide expression of type I Na+-phosphate cotransporter 3 (NPT3/SLC17A2), a membrane potential-driven organic anion transporter. |
Volume: |
309 |
Issue: |
2 |
Pages: |
C71-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kittayaruksakul S |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule. |
Volume: |
302 |
Issue: |
5 |
Pages: |
F552-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray DL |
Year: |
2001 |
Journal: |
Exp Lung Res |
Title: |
The effects of a binary mixture of benzo(a)pyrene and 7H-dibenzo(c,g)carbazole on lung tumors and K-ras oncogene mutations in strain A/J mice. |
Volume: |
27 |
Issue: |
3 |
Pages: |
245-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lidsky AS |
Year: |
1985 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. |
Volume: |
82 |
Issue: |
18 |
Pages: |
6221-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cohen H |
Year: |
1996 |
Journal: |
Eur J Biochem |
Title: |
Identification of differentially expressed genes during hepatocytes development and characterization of their prenatal hormonal induction. |
Volume: |
242 |
Issue: |
3 |
Pages: |
550-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lei XD |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system. |
Volume: |
95 |
Issue: |
4 |
Pages: |
1500-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nesnow S |
Year: |
1998 |
Journal: |
Exp Lung Res |
Title: |
Mechanistic relationships between DNA adducts, oncogene mutations, and lung tumorigenesis in strain A mice. |
Volume: |
24 |
Issue: |
4 |
Pages: |
395-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosoyamada M |
Year: |
1999 |
Journal: |
Am J Physiol |
Title: |
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. |
Volume: |
276 |
Issue: |
1 Pt 2 |
Pages: |
F122-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang ZY |
Year: |
1989 |
Journal: |
Carcinogenesis |
Title: |
Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols. |
Volume: |
10 |
Issue: |
2 |
Pages: |
411-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu Z |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor. |
Volume: |
66 |
Issue: |
2 |
Pages: |
755-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Courter LA |
Year: |
2007 |
Journal: |
Toxicol Sci |
Title: |
Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1. |
Volume: |
95 |
Issue: |
1 |
Pages: |
63-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Franceschi L |
Year: |
2008 |
Journal: |
FASEB J |
Title: |
Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1849-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zakrzewicz A |
Year: |
2007 |
Journal: |
Circulation |
Title: |
Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension. |
Volume: |
115 |
Issue: |
23 |
Pages: |
2957-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morecroft I |
Year: |
2010 |
Journal: |
Cardiovasc Res |
Title: |
In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. |
Volume: |
85 |
Issue: |
3 |
Pages: |
593-603 |
|
•
•
•
•
•
|
Publication |
First Author: |
White K |
Year: |
2011 |
Journal: |
Physiol Genomics |
Title: |
Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. |
Volume: |
43 |
Issue: |
8 |
Pages: |
417-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paulin R |
Year: |
2011 |
Journal: |
Circulation |
Title: |
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. |
Volume: |
123 |
Issue: |
11 |
Pages: |
1205-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nasim MT |
Year: |
2012 |
Journal: |
Hum Mol Genet |
Title: |
BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH. |
Volume: |
21 |
Issue: |
11 |
Pages: |
2548-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siddens LK |
Year: |
2012 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. |
Volume: |
264 |
Issue: |
3 |
Pages: |
377-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bauer PM |
Year: |
2012 |
Journal: |
Cardiovasc Res |
Title: |
Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1. |
Volume: |
93 |
Issue: |
4 |
Pages: |
682-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu YR |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension. |
Volume: |
48 |
Issue: |
5 |
Pages: |
647-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Satwiko MG |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Targeted activation of endothelin-1 exacerbates hypoxia-induced pulmonary hypertension. |
Volume: |
465 |
Issue: |
3 |
Pages: |
356-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paulin R |
Year: |
2014 |
Journal: |
Circ Res |
Title: |
The metabolic theory of pulmonary arterial hypertension. |
Volume: |
115 |
Issue: |
1 |
Pages: |
148-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wright AF |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
Oestrogen receptor alpha in pulmonary hypertension. |
Volume: |
106 |
Issue: |
2 |
Pages: |
206-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sysol JR |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1. |
Volume: |
314 |
Issue: |
3 |
Pages: |
L461-L472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xue C |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation. |
Volume: |
37 |
Issue: |
6 |
Pages: |
1138-1146 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hensley MK |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Emerging therapeutics in pulmonary hypertension. |
Volume: |
314 |
Issue: |
5 |
Pages: |
L769-L781 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tojais NF |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-β in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension. |
Volume: |
37 |
Issue: |
8 |
Pages: |
1559-1569 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen G |
Year: |
2018 |
Journal: |
J Exp Med |
Title: |
Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice. |
Volume: |
215 |
Issue: |
8 |
Pages: |
2175-2195 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao H |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase. |
Volume: |
9 |
Issue: |
1 |
Pages: |
9949 |
|
•
•
•
•
•
|
Publication |
First Author: |
George J |
Year: |
2011 |
Journal: |
J Hypertens |
Title: |
Transgenic expression of human matrix metalloproteinase-9 augments monocrotaline-induced pulmonary arterial hypertension in mice. |
Volume: |
29 |
Issue: |
2 |
Pages: |
299-308 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen M |
Year: |
2020 |
Journal: |
Exp Cell Res |
Title: |
A20 attenuates hypoxia-induced pulmonary arterial hypertension by inhibiting NF-κB activation and pulmonary artery smooth muscle cell proliferation. |
Volume: |
390 |
Issue: |
2 |
Pages: |
111982 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan J |
Year: |
2020 |
Journal: |
Int J Biol Sci |
Title: |
Upregulation of miR-335-3p by NF-κB Transcriptional Regulation Contributes to the Induction of Pulmonary Arterial Hypertension via APJ during Hypoxia. |
Volume: |
16 |
Issue: |
3 |
Pages: |
515-528 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu X |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
Cannabidiol attenuates pulmonary arterial hypertension by improving vascular smooth muscle cells mitochondrial function. |
Volume: |
11 |
Issue: |
11 |
Pages: |
5267-5278 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masaki T |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension. |
Volume: |
118 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Novoyatleva T |
Year: |
2013 |
Journal: |
Basic Res Cardiol |
Title: |
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction. |
Volume: |
108 |
Issue: |
2 |
Pages: |
325 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xing Y |
Year: |
2021 |
Journal: |
FASEB J |
Title: |
The LPS induced pyroptosis exacerbates BMPR2 signaling deficiency to potentiate SLE-PAH. |
Volume: |
35 |
Issue: |
12 |
Pages: |
e22044 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Y |
Year: |
2022 |
Journal: |
Hypertension |
Title: |
Caspase-4/11-Mediated Pulmonary Artery Endothelial Cell Pyroptosis Contributes to Pulmonary Arterial Hypertension. |
Volume: |
79 |
Issue: |
3 |
Pages: |
536-548 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida Y |
Year: |
2022 |
Journal: |
J Mol Cell Cardiol |
Title: |
Genetic and functional analyses of TBX4 reveal novel mechanisms underlying pulmonary arterial hypertension. |
Volume: |
171 |
|
Pages: |
105-116 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnes EA |
Year: |
2023 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension. |
Volume: |
325 |
Issue: |
6 |
Pages: |
L741-L755 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
452
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
498
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
488
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
447
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
403
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
447
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Majid DSA |
Year: |
2021 |
Journal: |
Physiol Rep |
Title: |
Angiotensin II-induced natriuresis is attenuated in knockout mice lacking the receptors for tumor necrosis factor-α. |
Volume: |
9 |
Issue: |
15 |
Pages: |
e14942 |
|
•
•
•
•
•
|
Publication |
First Author: |
Knaapen AM |
Year: |
2007 |
Journal: |
Mutat Res |
Title: |
The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis. |
Volume: |
621 |
Issue: |
1-2 |
Pages: |
31-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Calvier L |
Year: |
2019 |
Journal: |
Circ Res |
Title: |
LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation. |
Volume: |
124 |
Issue: |
12 |
Pages: |
1778-1785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luiking YC |
Year: |
2005 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
The role of NOS2 and NOS3 in renal protein and arginine metabolism during early endotoxemia in mice. |
Volume: |
288 |
Issue: |
4 |
Pages: |
F816-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haque MZ |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Reduced renal responses to nitric oxide synthase inhibition in mice lacking the gene for gp91phox subunit of NAD(P)H oxidase. |
Volume: |
295 |
Issue: |
3 |
Pages: |
F758-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chavan H |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). |
Volume: |
287 |
Issue: |
38 |
Pages: |
32054-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robles R |
Year: |
2000 |
Journal: |
Endocrinology |
Title: |
The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse. |
Volume: |
141 |
Issue: |
1 |
Pages: |
450-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Driscoll CA |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro. |
Volume: |
13 |
Issue: |
12 |
Pages: |
e0209690 |
|
•
•
•
•
•
|