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Search results 501 to 600 out of 6883 for Pax6

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Type Details Score
GXD Expression
Probe: MGI:5910082
Assay Type: Immunohistochemistry
Annotation Date: 2018-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6159121
Age: embryonic day 11.5
Image: S2F
Note: Authors report compound mutant embryos had patterns of expression indistinguishable from those of Sox2 +/- or Pax6 Sey/+ single heterozygous mutants.
Specimen Label: S2F
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:2150299
Assay Type: RNA in situ
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:2150342
Age: embryonic day 14.0
Image: 6I
Note: Mutated Pax6 transcript detected in its normal domain; significantly downregulated in lateral cortical VZ, specifically within the domain of ectopic GSH2 expression.
Specimen Label: 6I
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1928078
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7432600
Age: embryonic day 12.5
Note: Expressed in the p2 domain (gives rise to V2 interneurons), which was dorsal to the motor neuron progenitor domain (low Pax6 expression).
Specimen Label: 5C +/+ E12.5
Detected: true
Specimen Num: 3
Publication  
First Author: Li Z
Year: 2018
Journal: eNeuro
Title: Zic4-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Pax6 Function.
Volume: 5
Issue: 5
Publication  
First Author: Burgess D
Year: 2010
Journal: BMC Dev Biol
Title: Activated Ras alters lens and corneal development through induction of distinct downstream targets.
Volume: 10
Pages: 13
GXD Expression
Probe: MGI:2150299
Assay Type: RNA in situ
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2150342
Age: embryonic day 12.5
Image: 5E
Note: Expression of mutated Pax6 transcript in its normal domain; downregulated in cortical ventricular zone (VZ), in the lateral-most part of the lateral ganglionic eminence (LGE), specifically within the domain of ectopic GSH2 expression.
Specimen Label: 5E
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360666
Age: embryonic day 14.5
Image: 3E
Note: Expression was detected in interneurons. There was some co-expression with Gata3 positive V2b interneurons. Only the Pax6 interneurons settled in the ventral spinal cord coexpressed Gata3, and not the Pax6 interneurons when they migrate out of the ventricular zone.
Specimen Label: 3E
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360666
Age: embryonic day 14.5
Image: 4C
Note: Expression was detected in interneurons. There was some co-expression with Pax2 positive ventral V0 interneurons and with Gata3 positive V2b interneurons. There were also Pax6 positive interneurons that do not express either Pax2 or Gata3.
Specimen Label: 4C
Detected: true
Specimen Num: 9
Allele  
Name: Pax6 upstream antisense RNA; wild type
Allele Type: Not Specified
Publication
First Author: Jean D
Year: 1999
Journal: Mech Dev
Title: Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk.
Volume: 84
Issue: 1-2
Pages: 31-40
Publication
First Author: Xie Q
Year: 2011
Journal: J Biol Chem
Title: The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.
Volume: 286
Issue: 50
Pages: 43259-71
HT Experiment
Series Id: GSE13244
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Wurm A
Year: 2008
Journal: Exp Eye Res
Title: Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11.
Volume: 86
Issue: 6
Pages: 895-907
Publication
First Author: van der Meer-de Jong R
Year: 1990
Journal: Genomics
Title: Location of the gene involving the small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2).
Volume: 7
Issue: 2
Pages: 270-5
Publication
First Author: Ramaesh T
Year: 2009
Journal: Exp Eye Res
Title: Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.
Volume: 89
Issue: 2
Pages: 263-73
ncRNA Gene
Type: ncRNA_gene
Organism: Mus caroli
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
lncRNA Gene
Type: lncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: Mus pahari
ncRNA Gene
Type: ncRNA_gene
Organism: Mus spretus
Publication
First Author: Li Y
Year: 2009
Journal: Dev Dyn
Title: Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development.
Volume: 238
Issue: 9
Pages: 2388-400
Publication
First Author: Dohrmann C
Year: 2000
Journal: Mech Dev
Title: Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas.
Volume: 92
Issue: 1
Pages: 47-54
Publication
First Author: Xu S
Year: 2007
Journal: Dev Biol
Title: The proliferation and expansion of retinal stem cells require functional Pax6.
Volume: 304
Issue: 2
Pages: 713-21
Publication
First Author: Zhang Y
Year: 2008
Journal: Dev Biol
Title: Dominant inhibition of lens placode formation in mice.
Volume: 323
Issue: 1
Pages: 53-63
Publication
First Author: Hanson I
Year: 1995
Journal: Trends Genet
Title: Pax6: more than meets the eye.
Volume: 11
Issue: 7
Pages: 268-72
Publication
First Author: Bäumer N
Year: 2003
Journal: Development
Title: Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6.
Volume: 130
Issue: 13
Pages: 2903-15
Publication
First Author: Kredo-Russo S
Year: 2012
Journal: Development
Title: Pancreas-enriched miRNA refines endocrine cell differentiation.
Volume: 139
Issue: 16
Pages: 3021-31
Publication
First Author: Hochstim C
Year: 2008
Journal: Cell
Title: Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code.
Volume: 133
Issue: 3
Pages: 510-22
Publication
First Author: Simirskii VN
Year: 2007
Journal: Dev Biol
Title: Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.
Volume: 306
Issue: 2
Pages: 658-68
Publication
First Author: Lek M
Year: 2010
Journal: Development
Title: A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning.
Volume: 137
Issue: 23
Pages: 4051-60
Publication
First Author: Lord-Grignon J
Year: 2006
Journal: Gene Expr Patterns
Title: Identification of genes expressed in retinal progenitor/stem cell colonies isolated from the ocular ciliary body of adult mice.
Volume: 6
Issue: 8
Pages: 992-9
Publication
First Author: Menuchin-Lasowski Y
Year: 2016
Journal: Development
Title: Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.
Volume: 143
Issue: 15
Pages: 2829-41
Publication
First Author: Dorà NJ
Year: 2014
Journal: PLoS One
Title: Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites.
Volume: 9
Issue: 10
Pages: e109193
Publication
First Author: Ruiz-Reig N
Year: 2018
Journal: Brain Struct Funct
Title: The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.
Volume: 223
Issue: 7
Pages: 3279-3295
Publication
First Author: Molnár Z
Year: 2003
Journal: Cereb Cortex
Title: Choreography of early thalamocortical development.
Volume: 13
Issue: 6
Pages: 661-9
Publication
First Author: Chen Y
Year: 2008
Journal: Development
Title: Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis.
Volume: 135
Issue: 17
Pages: 2939-48
Publication  
First Author: Teo ZL
Year: 2014
Journal: Exp Eye Res
Title: Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.
Volume: 121
Pages: 130-42
Publication
First Author: Wolf L
Year: 2013
Journal: Nucleic Acids Res
Title: Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.
Volume: 41
Issue: 22
Pages: 10199-214
Publication  
First Author: Wang L
Year: 2011
Journal: Neural Dev
Title: Basal progenitor cells in the embryonic mouse thalamus - their molecular characterization and the role of neurogenins and Pax6.
Volume: 6
Pages: 35
Publication
First Author: He S
Year: 2010
Journal: Epigenetics Chromatin
Title: Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.
Volume: 3
Issue: 1
Pages: 21
Publication
First Author: Huang J
Year: 2011
Journal: Dev Biol
Title: The mechanism of lens placode formation: a case of matrix-mediated morphogenesis.
Volume: 355
Issue: 1
Pages: 32-42
Publication
First Author: Zhang J
Year: 2015
Journal: PLoS One
Title: Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development.
Volume: 10
Issue: 1
Pages: e0117089
Publication
First Author: Matsushima D
Year: 2011
Journal: Development
Title: Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6.
Volume: 138
Issue: 3
Pages: 443-54
Publication
First Author: Kleinjan DA
Year: 2001
Journal: Hum Mol Genet
Title: Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6.
Volume: 10
Issue: 19
Pages: 2049-59
Publication  
First Author: Hogan BL
Year: 1986
Journal: J Embryol Exp Morphol
Title: Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse.
Volume: 97
Pages: 95-110
Publication
First Author: Machon O
Year: 2010
Journal: Genesis
Title: Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/beta-catenin signaling in the lens surface ectoderm.
Volume: 48
Issue: 2
Pages: 86-95
Publication
First Author: Larsson LI
Year: 1998
Journal: Mech Dev
Title: Pax 4 and 6 regulate gastrointestinal endocrine cell development.
Volume: 79
Issue: 1-2
Pages: 153-9
Publication
First Author: Duquette PM
Year: 2010
Journal: PLoS One
Title: Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits.
Volume: 5
Issue: 10
Pages: e13232
HT Experiment
Series Id: GSE49216
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Carbe C
Year: 2013
Journal: J Biol Chem
Title: An allelic series at the paired box gene 6 (Pax6) locus reveals the functional specificity of Pax genes.
Volume: 288
Issue: 17
Pages: 12130-41
Publication
First Author: Smith AN
Year: 2009
Journal: Development
Title: Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis.
Volume: 136
Issue: 17
Pages: 2977-85
Publication
First Author: Cain S
Year: 2008
Journal: Dev Biol
Title: Differential requirement for beta-catenin in epithelial and fiber cells during lens development.
Volume: 321
Issue: 2
Pages: 420-33
Publication
First Author: Andrews GL
Year: 2003
Journal: J Neurosci
Title: R-cadherin is a Pax6-regulated, growth-promoting cue for pioneer axons.
Volume: 23
Issue: 30
Pages: 9873-80
Publication
First Author: Szabó NE
Year: 2011
Journal: PLoS One
Title: Interaction between axons and specific populations of surrounding cells is indispensable for collateral formation in the mammillary system.
Volume: 6
Issue: 5
Pages: e20315
Publication
First Author: Pattabiraman K
Year: 2014
Journal: Neuron
Title: Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex.
Volume: 82
Issue: 5
Pages: 989-1003
Publication
First Author: Sakurai K
Year: 2008
Journal: J Neurosci
Title: The neurogenesis-controlling factor, Pax6, inhibits proliferation and promotes maturation in murine astrocytes.
Volume: 28
Issue: 18
Pages: 4604-12
Publication
First Author: Quinn JC
Year: 1997
Journal: Anat Embryol (Berl)
Title: Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice.
Volume: 196
Issue: 4
Pages: 311-21
Publication
First Author: Kucerova R
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Cell surface glycoconjugate abnormalities and corneal epithelial wound healing in the pax6+/- mouse model of aniridia-related keratopathy.
Volume: 47
Issue: 12
Pages: 5276-82
Publication  
First Author: Pirity MK
Year: 2007
Journal: BMC Dev Biol
Title: Rybp, a polycomb complex-associated protein, is required for mouse eye development.
Volume: 7
Pages: 39
Allele
Name: Pax6 upstream antisense RNA; targeted mutation 1, William C Skarnes
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: Pax6 upstream antisense RNA; targeted mutation 1.1, William C Skarnes
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Martinez G
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
Volume: 50
Issue: 10
Pages: 4794-806
GXD Expression    
Probe: MGI:6293888
Assay Type: RT-PCR
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717223
Stage: TS23
Assay Id: MGI:6293907
Age: embryonic day 15.5
Image: 5
Specimen Label: Pax6 cKO
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6293887
Assay Type: RT-PCR
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667323
Stage: TS23
Assay Id: MGI:6293895
Age: embryonic day 15.5
Image: 1
Specimen Label: Pax6 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6293887
Assay Type: RT-PCR
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717223
Stage: TS23
Assay Id: MGI:6293895
Age: embryonic day 15.5
Image: 1
Specimen Label: Pax6 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367267
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 Het
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367267
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367267
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367268
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367268
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 Het
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7367233
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367268
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7367235
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367269
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7367235
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367269
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 Het
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7367235
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367269
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7367237
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367270
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7367237
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367270
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 Het
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7367237
Assay Type: RT-PCR
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7367270
Age: embryonic day 14.5
Image: S1
Specimen Label: Pax6 KO
Detected: true
Specimen Num: 3
Publication
First Author: He S
Year: 2016
Journal: Development
Title: Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.
Volume: 143
Issue: 11
Pages: 1937-47
Publication
First Author: Antosova B
Year: 2016
Journal: PLoS Genet
Title: The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.
Volume: 12
Issue: 12
Pages: e1006441
Publication
First Author: Pathania M
Year: 2016
Journal: Differentiation
Title: β1-integrin controls cell fate specification in early lens development.
Volume: 92
Issue: 4
Pages: 133-147
Publication
First Author: Hammond KL
Year: 1998
Journal: Mech Dev
Title: Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb.
Volume: 74
Issue: 1-2
Pages: 121-31
Publication    
First Author: Coré N
Year: 2020
Journal: Elife
Title: Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions between Vax1 and Pax6.
Volume: 9
Publication  
First Author: Mirjalili Mohanna SZ
Year: 2020
Journal: Mol Ther Methods Clin Dev
Title: Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia.
Volume: 17
Pages: 478-490
Publication
First Author: Warren N
Year: 1999
Journal: Cereb Cortex
Title: The transcription factor, Pax6, is required for cell proliferation and differentiation in the developing cerebral cortex.
Volume: 9
Issue: 6
Pages: 627-35
Publication
First Author: Collinson JM
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse.
Volume: 45
Issue: 4
Pages: 1101-8
Publication
First Author: Curto GG
Year: 2007
Journal: Brain Res
Title: Modifications of the retina neuronal populations of the heterozygous mutant small eye mouse, the Sey(Dey).
Volume: 1127
Issue: 1
Pages: 163-76