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Search results 501 to 600 out of 911 for Pdgfb

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Type Details Score
Publication
First Author: Cullen M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.
Volume: 108
Issue: 14
Pages: 5759-64
Publication
First Author: Wang CC
Year: 2000
Journal: Dev Biol
Title: Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera.
Volume: 224
Issue: 2
Pages: 152-67
Publication    
First Author: Qu X
Year: 2019
Journal: JCI Insight
Title: Tie2 regulates endocardial sprouting and myocardial trabeculation.
Volume: 5
Publication  
First Author: Uijtdewilligen PJE
Year: 2018
Journal: Biomed Res Int
Title: Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development.
Volume: 2018
Pages: 9873471
Publication  
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
Publication
First Author: Li S
Year: 2016
Journal: Biol Reprod
Title: Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.
Volume: 94
Issue: 2
Pages: 41
Publication
First Author: Naillat F
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model.
Volume: 1870
Issue: 5
Pages: 167180
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Tozer S
Year: 2007
Journal: Development
Title: Involvement of vessels and PDGFB in muscle splitting during chick limb development.
Volume: 134
Issue: 14
Pages: 2579-91
Publication
First Author: Hede SM
Year: 2009
Journal: Glia
Title: GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background.
Volume: 57
Issue: 11
Pages: 1143-53
Allele
Name: platelet derived growth factor, B polypeptide; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Christer Betsholtz
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Christer Betsholtz
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 2, Heikki Rauvala
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Publication
First Author: Kato M
Year: 2002
Journal: Biochem Biophys Res Commun
Title: WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation.
Volume: 291
Issue: 1
Pages: 41-7
Publication
First Author: Aspenström P
Year: 2002
Journal: Exp Cell Res
Title: The WASP-binding protein WIRE has a role in the regulation of the actin filament system downstream of the platelet-derived growth factor receptor.
Volume: 279
Issue: 1
Pages: 21-33
Protein Domain
Type: Family
Description: WAS/WASL-interacting protein family member 2 (WIPF2, also known as WICH or WIRE) contains a verprolin-homology (V) region. It plays an important role in actin-microspike formation through cooperation with WASL (neural Wiskott-Aldrich syndrome protein, also known as N-WASP) []. It plays an active role in the formation of cell surface protrusions downstream of activated PDGFB (platelet-derived growth factor B) receptors [].
Strain
Attribute String: mutant stock, transgenic
Allele
Name: transgene insertion 90, Uppsala University
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion #, Michio Tamatani
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: 129X1/SvJ * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Claxton S
Year: 2008
Journal: Genesis
Title: Efficient, inducible Cre-recombinase activation in vascular endothelium.
Volume: 46
Issue: 2
Pages: 74-80
Allele
Name: transgene insertion 1, Vassilis I Zannis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, John Hardy
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele  
Name: engrailed 1; targeted mutation 1, Monica Nister
Allele Type: Targeted
Publication
First Author: Tamatani M
Year: 2001
Journal: Nat Med
Title: ORP150 protects against hypoxia/ischemia-induced neuronal death.
Volume: 7
Issue: 3
Pages: 317-23
Publication
First Author: Nakagomi T
Year: 2004
Journal: Am J Pathol
Title: The 150-kilodalton oxygen-regulated protein ameliorates lipopolysaccharide-induced acute lung injury in mice.
Volume: 165
Issue: 4
Pages: 1279-88
Allele
Name: transgene insertion 1, Marcus Fruttiger
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: transgene insertion L, Keiji Wada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Tg(PDGFB-Hyou1)#Tam/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(PDGFB-Hyou1)#Tam/?
Background: involves: BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Pavlov I
Year: 2002
Journal: Mol Cell Neurosci
Title: Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.
Volume: 20
Issue: 2
Pages: 330-42
Publication
First Author: Andrae J
Year: 2004
Journal: Mol Cell Neurosci
Title: Forced expression of platelet-derived growth factor B in the mouse cerebellar primordium changes cell migration during midline fusion and causes cerebellar ectopia.
Volume: 26
Issue: 2
Pages: 308-21
Allele
Name: transgene insertion 3, John Hardy
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 2, John Hardy
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Hartmann J
Year: 2004
Journal: Neuroscience
Title: Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice.
Volume: 125
Issue: 4
Pages: 1009-17
Publication
First Author: Yu WH
Year: 2005
Journal: J Cell Biol
Title: Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.
Volume: 171
Issue: 1
Pages: 87-98
Publication
First Author: Pérez-Jiménez MM
Year: 2021
Journal: Nat Commun
Title: Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases.
Volume: 12
Issue: 1
Pages: 49
Strain
Attribute String: congenic, targeted mutation
Publication
First Author: Perbellini F
Year: 2018
Journal: Cardiovasc Res
Title: Investigation of cardiac fibroblasts using myocardial slices.
Volume: 114
Issue: 1
Pages: 77-89
Publication
First Author: McCurdy S
Year: 2022
Journal: FASEB J
Title: β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.
Volume: 36
Issue: 12
Pages: e22629
Allele
Name: transgene insertion H, Keiji Wada
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Genotype
Symbol: En1/En1
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: En1/En1<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tg(PDGFB-UCHL1*I93M)HWada/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(PDGFB-UCHL1*I93M)LWada/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Kitao Y
Year: 2001
Journal: J Clin Invest
Title: Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity.
Volume: 108
Issue: 10
Pages: 1439-50
Publication
First Author: Kitano H
Year: 2004
Journal: Brain Res
Title: ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brain.
Volume: 1015
Issue: 1-2
Pages: 122-8
Publication
First Author: Kitao Y
Year: 2004
Journal: J Neurosci
Title: ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development.
Volume: 24
Issue: 6
Pages: 1486-96
Publication
First Author: Park H
Year: 2019
Journal: Nat Commun
Title: Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy.
Volume: 10
Issue: 1
Pages: 5243
Publication
First Author: Zhang L
Year: 2020
Journal: Genet Med
Title: Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Volume: 22
Issue: 1
Pages: 77-84
Publication
First Author: Yu P
Year: 2019
Journal: J Cereb Blood Flow Metab
Title: Role of microRNA-126 in vascular cognitive impairment in mice.
Volume: 39
Issue: 12
Pages: 2497-2511
Publication  
First Author: Sewduth RN
Year: 2017
Journal: Sci Signal
Title: PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability.
Volume: 10
Issue: 464
Publication  
First Author: Koskimäki J
Year: 2019
Journal: JCI Insight
Title: Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.
Volume: 4
Issue: 3
Allele
Name: transgene insertion 310, Karin Forsberg-Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 312, Karin Forsberg-Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Krit1/Krit1 Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pdzrn3/Pdzrn3 Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
Background: involves: C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdh5/Cdh5 Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Shih AH
Year: 2004
Journal: Cancer Res
Title: Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis.
Volume: 64
Issue: 14
Pages: 4783-9
Publication
First Author: Fan Y
Year: 2024
Journal: Nat Commun
Title: Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.
Volume: 15
Issue: 1
Pages: 2939
Publication
First Author: Sheikh AQ
Year: 2018
Journal: Cell Rep
Title: Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension.
Volume: 23
Issue: 4
Pages: 1152-1165
Publication  
First Author: Issitt T
Year: 2019
Journal: iScience
Title: Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.
Volume: 11
Pages: 205-223
Publication
First Author: Rothenberg C
Year: 2010
Journal: Hum Mol Genet
Title: Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
Volume: 19
Issue: 16
Pages: 3219-32