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Search results 501 to 600 out of 799 for Prkcz

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:7541037
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541115
Age: embryonic day 5.5
Image: S3d WT
Note: Enriched in the apical region of visceral endoderm cells.
Specimen Label: S3d WT
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:7541037
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541115
Age: embryonic day 5.5
Image: S3d -/-
Note: More broadly distributed in the cells.
Specimen Label: S3d -/-
Detected: true
Specimen Num: 10
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Publication
18003854 | J:141561
First Author: Lee A
Year: 2007
Journal: J Neurosci
Title: Phosphorylation of the Ca2+-binding protein CaBP4 by protein kinase C zeta in photoreceptors.
Volume: 27
Issue: 46
Pages: 12743-54
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Publication
24117625 | J:207867
First Author: Vogt-Eisele A
Year: 2014
Journal: J Neurochem
Title: KIBRA (KIdney/BRAin protein) regulates learning and memory and stabilizes Protein kinase Mζ.
Volume: 128
Issue: 5
Pages: 686-700
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Publication
28743803 | J:258551
 
First Author: Chen TC
Year: 2017
Journal: Sci Signal
Title: The glucocorticoid-Angptl4-ceramide axis induces insulin resistance through PP2A and PKCζ.
Volume: 10
Issue: 489
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Publication
31796630 | J:286192
 
First Author: Levasseur EM
Year: 2019
Journal: Sci Signal
Title: Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
Volume: 12
Issue: 610
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Publication
12881425 | J:84916
First Author: Duran A
Year: 2003
Journal: EMBO J
Title: Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation.
Volume: 22
Issue: 15
Pages: 3910-8
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Publication
16527821 | J:113737
First Author: Frey RS
Year: 2006
Journal: J Biol Chem
Title: Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells.
Volume: 281
Issue: 23
Pages: 16128-38
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Publication
21127255 | J:167306
First Author: Li XY
Year: 2010
Journal: Science
Title: Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.
Volume: 330
Issue: 6009
Pages: 1400-4
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Publication
30660448 | J:295068
First Author: Noguchi N
Year: 2019
Journal: J Dermatol Sci
Title: Atypical protein kinase C isoforms differentially regulate directional keratinocyte migration during wound healing.
Volume: 93
Issue: 2
Pages: 101-108
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Publication
21653884 | J:173454
First Author: Sengupta A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
Volume: 108
Issue: 24
Pages: 9957-62
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Publication
30610188 | J:270586
First Author: Nayak RC
Year: 2019
Journal: Nat Commun
Title: The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors.
Volume: 10
Issue: 1
Pages: 46
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Publication
18955501 | J:144073
First Author: Galvez AS
Year: 2009
Journal: Mol Cell Biol
Title: Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo.
Volume: 29
Issue: 1
Pages: 104-15
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Publication
23334392 | J:311485
First Author: Hartleben B
Year: 2013
Journal: J Am Soc Nephrol
Title: aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.
Volume: 24
Issue: 2
Pages: 253-67
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Publication
16931174 | J:115984
First Author: Kovac J
Year: 2007
Journal: Gene Expr Patterns
Title: Expression of the atypical protein kinase C (aPKC) isoforms iota/lambda and zeta during mouse embryogenesis.
Volume: 7
Issue: 1-2
Pages: 187-96
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Publication
33207226 | J:300513
First Author: Kasashima H
Year: 2021
Journal: Dev Cell
Title: Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Volume: 56
Issue: 1
Pages: 95-110.e10
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Publication
20007975 | J:159761
First Author: Yao H
Year: 2010
Journal: J Biol Chem
Title: Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.
Volume: 285
Issue: 8
Pages: 5405-16
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Publication
17878344 | J:152354
First Author: Moulakakis C
Year: 2007
Journal: J Immunol
Title: Surfactant protein A activation of atypical protein kinase C zeta in IkappaB-alpha-dependent anti-inflammatory immune regulation.
Volume: 179
Issue: 7
Pages: 4480-91
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Publication
19028678 | J:147234
First Author: Barros SA
Year: 2009
Journal: J Biol Chem
Title: Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport.
Volume: 284
Issue: 5
Pages: 2672-9
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Publication
25617472 | J:232677
First Author: Metz PJ
Year: 2015
Journal: J Immunol
Title: Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι.
Volume: 194
Issue: 5
Pages: 2249-59
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Publication
21829704 | J:263374
First Author: Sakaguchi M
Year: 2011
Journal: PLoS One
Title: TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.
Volume: 6
Issue: 8
Pages: e23132
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Publication
8797824 | J:35282
First Author: Díaz-Meco MT
Year: 1996
Journal: Cell
Title: The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C.
Volume: 86
Issue: 5
Pages: 777-86
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Publication
17849438 | J:125492
First Author: Wu X
Year: 2007
Journal: Dev Dyn
Title: Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development.
Volume: 236
Issue: 10
Pages: 2767-78
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Publication
18566367 | J:137180
First Author: Tomayko MM
Year: 2008
Journal: J Immunol
Title: Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities.
Volume: 181
Issue: 1
Pages: 27-38
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Publication
19682542 | J:155169
First Author: Yang TT
Year: 2009
Journal: Neurosci Lett
Title: Mediation of protein kinase C zeta in mu-opioid receptor activation for increase of glucose uptake into cultured myoblast C2C12 cells.
Volume: 465
Issue: 2
Pages: 177-80
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Publication
21911744 | J:189497
First Author: Velazquez-Garcia S
Year: 2011
Journal: Diabetes
Title: Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
Volume: 60
Issue: 10
Pages: 2546-59
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Publication
23313818 | J:194282
First Author: Liu H
Year: 2013
Journal: Dev Biol
Title: Atypical PKC, regulated by Rho GTPases and Mek/Erk, phosphorylates Ezrin during eight-cell embryocompaction.
Volume: 375
Issue: 1
Pages: 13-22
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Publication
23213435 | J:184584
First Author: Seidl S
Year: 2012
Journal: Biol Open
Title: Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling.
Volume: 1
Issue: 5
Pages: 436-45
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Publication
15893606 | J:99333
First Author: Matsuki T
Year: 2005
Journal: Brain Res Mol Brain Res
Title: Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system.
Volume: 136
Issue: 1-2
Pages: 231-54
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Publication
21131967 | J:170429
First Author: Levy D
Year: 2011
Journal: Nat Immunol
Title: Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Volume: 12
Issue: 1
Pages: 29-36
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Publication
14960283 | J:90010
First Author: Durán A
Year: 2004
Journal: Dev Cell
Title: The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.
Volume: 6
Issue: 2
Pages: 303-9
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Publication
23374352 | J:193453
First Author: Ma L
Year: 2013
Journal: Cell
Title: Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.
Volume: 152
Issue: 3
Pages: 599-611
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Publication
20620996 | J:163163
First Author: Lee SJ
Year: 2010
Journal: Cell Metab
Title: PKCzeta-regulated inflammation in the nonhematopoietic compartment is critical for obesity-induced glucose intolerance.
Volume: 12
Issue: 1
Pages: 65-77
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Publication
22820510 | J:189149
First Author: Ferdaoussi M
Year: 2012
Journal: Diabetologia
Title: G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.
Volume: 55
Issue: 10
Pages: 2682-2692
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Publication
15526032 | J:115464
First Author: Durán A
Year: 2004
Journal: EMBO J
Title: Crosstalk between PKCzeta and the IL4/Stat6 pathway during T-cell-mediated hepatitis.
Volume: 23
Issue: 23
Pages: 4595-605
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Publication
23791731 | J:199829
First Author: Hirate Y
Year: 2013
Journal: Curr Biol
Title: Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.
Volume: 23
Issue: 13
Pages: 1181-94
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Publication
21248257 | J:169141
First Author: Sender V
Year: 2011
Journal: J Immunol
Title: Pulmonary surfactant protein A enhances endolysosomal trafficking in alveolar macrophages through regulation of Rab7.
Volume: 186
Issue: 4
Pages: 2397-411
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Publication
29109255 | J:254318
First Author: Magnani ND
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.
Volume: 114
Issue: 47
Pages: E10178-E10186
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Publication
28143902 | J:260271
 
First Author: Sewduth RN
Year: 2017
Journal: Sci Signal
Title: PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability.
Volume: 10
Issue: 464
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Publication
26868297 | J:240076
First Author: Lakshmipathi J
Year: 2016
Journal: Diabetes
Title: PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.
Volume: 65
Issue: 5
Pages: 1283-96
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Publication
15882626 | J:98926
First Author: Gomes ER
Year: 2005
Journal: Cell
Title: Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells.
Volume: 121
Issue: 3
Pages: 451-63
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Publication
17971416 | J:128442
First Author: Odemis V
Year: 2007
Journal: J Cell Sci
Title: The chemokine SDF1 controls multiple steps of myogenesis through atypical PKCzeta.
Volume: 120
Issue: Pt 22
Pages: 4050-9
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Publication
19528321 | J:149986
First Author: McCaffrey LM
Year: 2009
Journal: Genes Dev
Title: The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis.
Volume: 23
Issue: 12
Pages: 1450-60
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Publication
19549684 | J:153162
First Author: Mashukova A
Year: 2009
Journal: J Cell Sci
Title: Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones.
Volume: 122
Issue: Pt 14
Pages: 2491-503
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Publication
37342904 | J:341951
First Author: Yang X
Year: 2023
Journal: FASEB J
Title: KLF7 promotes adipocyte inflammation and glucose metabolism disorder by activating the PKCζ/NF-κB pathway.
Volume: 37
Issue: 7
Pages: e23033
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Publication
17313651 | J:225407
First Author: Fritzius T
Year: 2007
Journal: FEBS J
Title: WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
Volume: 274
Issue: 6
Pages: 1552-66
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Publication
16849539 | J:112117
First Author: Oster H
Year: 2006
Journal: Cancer Res
Title: Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ mice.
Volume: 66
Issue: 14
Pages: 6955-63
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Publication
25070947 | J:216219
First Author: Anastasaki C
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation.
Volume: 23
Issue: 25
Pages: 6712-21
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Publication
18067887 | J:130330
First Author: Ralston A
Year: 2008
Journal: Dev Biol
Title: Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo.
Volume: 313
Issue: 2
Pages: 614-29
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Publication
23550155 | J:196173
First Author: Kim JY
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: c-Myc phosphorylation by PKCζ represses prostate tumorigenesis.
Volume: 110
Issue: 16
Pages: 6418-23
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Publication
27653691 | J:239118
First Author: Nakanishi Y
Year: 2016
Journal: Cell Rep
Title: Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι.
Volume: 16
Issue: 12
Pages: 3297-3310
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Publication
25655195 | J:221970
First Author: Witkowski MT
Year: 2015
Journal: Leukemia
Title: Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Volume: 29
Issue: 6
Pages: 1301-11
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Publication
30552022 | J:305332
First Author: Nakanishi Y
Year: 2018
Journal: Immunity
Title: Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance.
Volume: 49
Issue: 6
Pages: 1132-1147.e7
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Publication
25660024 | J:222050
     
First Author: Llado V
Year: 2015
Journal: Cell Rep
Title: Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ
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Publication
38815584 | J:349890
     
First Author: Kinoshita H
Year: 2024
Journal: Dev Cell
Title: Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation.
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Publication
29694894 | J:270865
First Author: Shelton PM
Year: 2018
Journal: Cell Rep
Title: The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.
Volume: 23
Issue: 4
Pages: 1178-1191
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Publication
27487217 | J:269076
First Author: Maître JL
Year: 2016
Journal: Nature
Title: Asymmetric division of contractile domains couples cell positioning and fate specification.
Volume: 536
Issue: 7616
Pages: 344-348
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Publication
21645497 | J:172711
First Author: Mayanglambam A
Year: 2011
Journal: Biochem Pharmacol
Title: Differential dephosphorylation of the protein kinase C-zeta (PKCζ) in an integrin αIIbβ3-dependent manner in platelets.
Volume: 82
Issue: 5
Pages: 505-13
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Publication
22232556 | J:182771
First Author: García-Hoz C
Year: 2012
Journal: J Biol Chem
Title: Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.
Volume: 287
Issue: 10
Pages: 7792-802
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Publication
23675446 | J:202127
First Author: Main H
Year: 2013
Journal: PLoS One
Title: Notch signaling maintains neural rosette polarity.
Volume: 8
Issue: 5
Pages: e62959
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Publication
30676318 | J:275948
   
First Author: Lawlor KT
Year: 2019
Journal: Elife
Title: Nephron progenitor commitment is a stochastic process influenced by cell migration.
Volume: 8
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Publication
15950600 | J:99397
First Author: Vinot S
Year: 2005
Journal: Dev Biol
Title: Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction.
Volume: 282
Issue: 2
Pages: 307-19
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Publication
15766745 | J:98298
First Author: Michaut MA
Year: 2005
Journal: Dev Biol
Title: Phosphorylated MARCKS: a novel centrosome component that also defines a peripheral subdomain of the cortical actin cap in mouse eggs.
Volume: 280
Issue: 1
Pages: 26-37
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Publication
14730360 | J:87887
First Author: Wesemann DR
Year: 2004
Journal: Nat Immunol
Title: TRADD interacts with STAT1-alpha and influences interferon-gamma signaling.
Volume: 5
Issue: 2
Pages: 199-207
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Publication
8670164 | J:33813
 
First Author: Frevert EU
Year: 1996
Journal: Biochem J
Title: Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.
Volume: 316 ( Pt 3)
Pages: 865-71
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Publication
12648500 | J:82635
First Author: Zhou X
Year: 2003
Journal: Dev Biol
Title: Differentiation of nonbeating embryonic stem cells into beating cardiomyocytes is dependent on downregulation of PKC beta and zeta in concert with upregulation of PKC epsilon.
Volume: 255
Issue: 2
Pages: 407-22
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Publication
14715240 | J:87712
First Author: Alt A
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Differential regulation of alpha6beta4 integrin by PKC isoforms in murine skin keratinocytes.
Volume: 314
Issue: 1
Pages: 17-23
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Publication
17220321 | J:121908
First Author: Dey R
Year: 2007
Journal: Infect Immun
Title: Leishmania donovani-induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: role of protein kinase Czeta and phosphatase.
Volume: 75
Issue: 5
Pages: 2136-42
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Publication
23392682 | J:194274
First Author: Lee SI
Year: 2013
Journal: J Neurosci
Title: Atypical protein kinase C and Par3 are required for proteoglycan-induced axon growth inhibition.
Volume: 33
Issue: 6
Pages: 2541-54
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Publication
33547760 | J:304327
First Author: Chen Z
Year: 2021
Journal: Genesis
Title: Atypical protein kinase C is essential for embryonic vascular development in mice.
Volume: 59
Issue: 3
Pages: e23412
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Publication
16792529 | J:225409
First Author: Fritzius T
Year: 2006
Journal: Biochem J
Title: A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.
Volume: 399
Issue: 1
Pages: 9-20
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Publication
10934474 | J:69174
First Author: Joberty G
Year: 2000
Journal: Nat Cell Biol
Title: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.
Volume: 2
Issue: 8
Pages: 531-9
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Publication
10934475 | J:63704
First Author: Lin D
Year: 2000
Journal: Nat Cell Biol
Title: A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity.
Volume: 2
Issue: 8
Pages: 540-7
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Publication
17092936 | J:118130
First Author: Feng Y
Year: 2007
Journal: J Biol Chem
Title: The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development.
Volume: 282
Issue: 1
Pages: 39-48
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Publication
19668197 | J:158132
First Author: Mori D
Year: 2009
Journal: Nat Cell Biol
Title: An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics.
Volume: 11
Issue: 9
Pages: 1057-68
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Publication
19470463 | J:151903
First Author: Fernandez-Marcos PJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-kappaB activation and invasive prostate carcinoma.
Volume: 106
Issue: 31
Pages: 12962-7
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Publication
24626928 | J:207600
First Author: Gros J
Year: 2014
Journal: Science
Title: Vertebrate limb bud formation is initiated by localized epithelial-to-mesenchymal transition.
Volume: 343
Issue: 6176
Pages: 1253-6
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Publication
20152182 | J:157918
First Author: Wang J
Year: 2010
Journal: Dev Cell
Title: CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.
Volume: 18
Issue: 1
Pages: 114-25
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Publication
30157434 | J:271615
First Author: Haag N
Year: 2018
Journal: Cell Rep
Title: The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea.
Volume: 24
Issue: 9
Pages: 2418-2431.e6
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Publication
17679097 | J:134814
First Author: Jaeschke A
Year: 2007
Journal: Mol Cell
Title: Metabolic stress signaling mediated by mixed-lineage kinases.
Volume: 27
Issue: 3
Pages: 498-508
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Publication
18650932 | J:139014
First Author: Joshi J
Year: 2008
Journal: EMBO J
Title: Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis.
Volume: 27
Issue: 16
Pages: 2181-93
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Publication
30126902 | J:270954
 
First Author: Bankaitis ED
Year: 2018
Journal: Development
Title: ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.
Volume: 145
Issue: 18
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Publication
26722124 | J:315858
 
First Author: Leung C
Year: 2015
Journal: J Am Heart Assoc
Title: Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development.
Volume: 5
Issue: 1
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