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Search results 501 to 600 out of 1688 for Prnp

0.032s
Type Details Score
Publication
First Author: Manson J
Year: 1992
Journal: Development
Title: The prion protein gene: a role in mouse embryogenesis?
Volume: 115
Issue: 1
Pages: 117-22
Publication
First Author: Pfeifer K
Year: 1993
Journal: Cell Biochem Funct
Title: Kinetics of expression of prion protein in uninfected and scrapie-infected N2a mouse neuroblastoma cells.
Volume: 11
Issue: 1
Pages: 1-11
Publication
First Author: Berg LJ
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Insights into the role of the immune system in prion diseases.
Volume: 91
Issue: 2
Pages: 429-32
Publication  
First Author: Farquhar CF
Year: 1994
Journal: J Gen Virol
Title: Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie.
Volume: 75 ( Pt 3)
Pages: 495-504
Publication
First Author: Hope J
Year: 1994
Journal: Biochem Soc Trans
Title: Scrapie, Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: the key role of a nerve membrane protein (PrP).
Volume: 22
Issue: 1
Pages: 159-63
Publication
First Author: Westaway D
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Structure and polymorphism of the mouse prion protein gene.
Volume: 91
Issue: 14
Pages: 6418-22
Publication
First Author: Carlson GA
Year: 1994
Journal: Philos Trans R Soc Lond B Biol Sci
Title: Genetics of prion diseases and prion diversity in mice.
Volume: 343
Issue: 1306
Pages: 363-9
Publication    
First Author: Prusiner SB
Journal: Harvey Lect
Title: Prion biology and diseases.
Volume: 87
Pages: 85-114
Publication
First Author: Lazarini F
Year: 1994
Journal: J Comp Pathol
Title: Astrocyte gene expression in experimental mouse scrapie.
Volume: 111
Issue: 1
Pages: 87-98
Publication
First Author: Windl O
Year: 1995
Journal: Gene
Title: A candidate marsupial PrP gene reveals two domains conserved in mammalian PrP proteins.
Volume: 159
Issue: 2
Pages: 181-6
Publication
First Author: Somerville RA
Year: 1996
Journal: Arch Virol
Title: The association between PrP and infectivity in scrapie and BSE infected mouse brain.
Volume: 141
Issue: 2
Pages: 275-89
Publication  
First Author: Lasmézas CI
Year: 1996
Journal: J Gen Virol
Title: Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy.
Volume: 77 ( Pt 7)
Pages: 1601-9
Publication
First Author: Kacser H
Year: 1996
Journal: J Theor Biol
Title: How many phenotypes from one genotype? The case of Prion diseases.
Volume: 182
Issue: 3
Pages: 209-18
Publication
First Author: Krasemann S
Year: 1996
Journal: J Immunol Methods
Title: Induction of antibodies against human prion proteins (PrP) by DNA-mediated immunization of PrP0/0 mice.
Volume: 199
Issue: 2
Pages: 109-18
Publication
First Author: Baybutt H
Year: 1997
Journal: Gene
Title: Characterisation of two promoters for prion protein (PrP) gene expression in neuronal cells.
Volume: 184
Issue: 1
Pages: 125-31
Publication
First Author: Loftus B
Year: 1997
Journal: Gene
Title: Characterization of a prion protein (PrP) gene from rabbit; a species with apparent resistance to infection by prions.
Volume: 184
Issue: 2
Pages: 215-9
Publication
First Author: Colling SB
Year: 1997
Journal: Brain Res
Title: Mossy fibre reorganization in the hippocampus of prion protein null mice.
Volume: 755
Issue: 1
Pages: 28-35
Publication
First Author: Billeter M
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Prion protein NMR structure and species barrier for prion diseases.
Volume: 94
Issue: 14
Pages: 7281-5
Publication
First Author: Muramoto T
Year: 1997
Journal: Nat Med
Title: Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix.
Volume: 3
Issue: 7
Pages: 750-5
Publication
First Author: Gabizon R
Year: 1997
Journal: Trends Genet
Title: Of mice and (mad) cows--transgenic mice help to understand prions.
Volume: 13
Issue: 7
Pages: 264-9
Publication
First Author: Kaneko K
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
Volume: 94
Issue: 19
Pages: 10069-74
Publication
First Author: James TL
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.
Volume: 94
Issue: 19
Pages: 10086-91
Publication
First Author: Nishida N
Year: 1997
Journal: Cell Mol Neurobiol
Title: Prion protein is necessary for latent learning and long-term memory retention.
Volume: 17
Issue: 5
Pages: 537-45
Publication
First Author: Raeber AJ
Year: 1997
Journal: EMBO J
Title: Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.
Volume: 16
Issue: 20
Pages: 6057-65
Publication
First Author: Korth C
Year: 1997
Journal: Nature
Title: Prion (PrPSc)-specific epitope defined by a monoclonal antibody.
Volume: 390
Issue: 6655
Pages: 74-7
Publication
First Author: Weber T
Year: 1997
Journal: Intervirology
Title: The spectrum of transmissible spongiform encephalopathies.
Volume: 40
Issue: 2-3
Pages: 198-212
Publication
First Author: Brown DR
Year: 1998
Journal: J Neurosci Res
Title: Prion protein fragment interacts with PrP-deficient cells.
Volume: 52
Issue: 3
Pages: 260-7
Publication
First Author: Schröder B
Year: 1998
Journal: Biochem Biophys Res Commun
Title: A differentially expressed prion gene mRNA is found in prion-infected mouse brains and in N2A cells but not in uninfected mice.
Volume: 251
Issue: 2
Pages: 423-8
Publication
First Author: Weissmann C
Year: 1999
Journal: J Biol Chem
Title: Molecular genetics of transmissible spongiform encephalopathies.
Volume: 274
Issue: 1
Pages: 3-6
Publication
First Author: Katamine S
Year: 1998
Journal: Cell Mol Neurobiol
Title: Impaired motor coordination in mice lacking prion protein.
Volume: 18
Issue: 6
Pages: 731-42
Publication
First Author: Supattapone S
Year: 1999
Journal: Cell
Title: Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice.
Volume: 96
Issue: 6
Pages: 869-78
Publication
First Author: Kuwahara C
Year: 1999
Journal: Nature
Title: Prions prevent neuronal cell-line death.
Volume: 400
Issue: 6741
Pages: 225-6
Publication  
First Author: Brimacombe DB
Year: 1999
Journal: Biochem J
Title: Characterization and polyanion-binding properties of purified recombinant prion protein.
Volume: 342 Pt 3
Pages: 605-13
Publication
First Author: Zuegg J
Year: 1999
Journal: Biochemistry
Title: Molecular dynamics simulations of human prion protein: importance of correct treatment of electrostatic interactions.
Volume: 38
Issue: 42
Pages: 13862-76
Publication
First Author: Dupuis L
Year: 2002
Journal: Mol Cell Neurosci
Title: Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis.
Volume: 19
Issue: 2
Pages: 216-24
Publication
First Author: Supattapone S
Year: 2001
Journal: J Virol
Title: Identification of two prion protein regions that modify scrapie incubation time.
Volume: 75
Issue: 3
Pages: 1408-13
Publication
First Author: Nandi PK
Year: 2002
Journal: J Mol Biol
Title: DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid.
Volume: 322
Issue: 1
Pages: 153-61
Publication
First Author: Perrier V
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Dominant-negative inhibition of prion replication in transgenic mice.
Volume: 99
Issue: 20
Pages: 13079-84
Publication
First Author: Russelakis-Carneiro M
Year: 2002
Journal: J Biol Chem
Title: Changes in the glycosylation pattern of prion protein in murine scrapie. Implications for the mechanism of neurodegeneration in prion diseases.
Volume: 277
Issue: 39
Pages: 36872-7
Publication
First Author: van Rheede T
Year: 2003
Journal: Mol Biol Evol
Title: Molecular evolution of the mammalian prion protein.
Volume: 20
Issue: 1
Pages: 111-21
Publication
First Author: Nunziante M
Year: 2003
Journal: J Biol Chem
Title: Essential role of the prion protein N terminus in subcellular trafficking and half-life of cellular prion protein.
Volume: 278
Issue: 6
Pages: 3726-34
Publication
First Author: Mironov A Jr
Year: 2003
Journal: J Neurosci
Title: Cytosolic prion protein in neurons.
Volume: 23
Issue: 18
Pages: 7183-93
Publication
First Author: Cordeiro Y
Year: 2004
Journal: J Biol Chem
Title: Hydration and packing effects on prion folding and beta-sheet conversion. High pressure spectroscopy and pressure perturbation calorimetry studies.
Volume: 279
Issue: 31
Pages: 32354-9
Publication
First Author: Legname G
Year: 2004
Journal: Science
Title: Synthetic mammalian prions.
Volume: 305
Issue: 5684
Pages: 673-6
Publication
First Author: Sakudo A
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Octapeptide repeat region and N-terminal half of hydrophobic region of prion protein (PrP) mediate PrP-dependent activation of superoxide dismutase.
Volume: 326
Issue: 3
Pages: 600-6
Publication
First Author: Scott MR
Year: 2005
Journal: J Virol
Title: Transmission barriers for bovine, ovine, and human prions in transgenic mice.
Volume: 79
Issue: 9
Pages: 5259-71
Publication
First Author: Pan T
Year: 2005
Journal: J Virol
Title: An aggregation-specific enzyme-linked immunosorbent assay: detection of conformational differences between recombinant PrP protein dimers and PrP(Sc) aggregates.
Volume: 79
Issue: 19
Pages: 12355-64
Publication
First Author: Castilla J
Year: 2005
Journal: FEBS Lett
Title: Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection.
Volume: 579
Issue: 27
Pages: 6237-46
Publication
First Author: Bian J
Year: 2006
Journal: Biochem Biophys Res Commun
Title: GFP-tagged PrP supports compromised prion replication in transgenic mice.
Volume: 340
Issue: 3
Pages: 894-900
Publication
First Author: Thompsett AR
Year: 2005
Journal: J Biol Chem
Title: High affinity binding between copper and full-length prion protein identified by two different techniques.
Volume: 280
Issue: 52
Pages: 42750-8
Publication
First Author: Gilch S
Year: 2006
Journal: Mol Cell Neurosci
Title: The prion protein requires cholesterol for cell surface localization.
Volume: 31
Issue: 2
Pages: 346-53
Publication
First Author: Roucou X
Year: 2005
Journal: Cell Death Differ
Title: Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells.
Volume: 12
Issue: 7
Pages: 783-95
Publication  
First Author: Hunter N
Year: 1994
Journal: Ann N Y Acad Sci
Title: Comparison of expression patterns of PrP mRNA in the developing sheep and mouse.
Volume: 724
Pages: 353-4
Publication
First Author: Nadal RC
Year: 2007
Journal: Free Radic Biol Med
Title: Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals.
Volume: 42
Issue: 1
Pages: 79-89
Publication
First Author: Martins SM
Year: 2006
Journal: J Biol Chem
Title: Formation of soluble oligomers and amyloid fibrils with physical properties of the scrapie isoform of the prion protein from the C-terminal domain of recombinant murine prion protein mPrP-(121-231).
Volume: 281
Issue: 36
Pages: 26121-8
Publication
First Author: Orsi A
Year: 2006
Journal: J Biol Chem
Title: Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein.
Volume: 281
Issue: 41
Pages: 30431-8
Publication
First Author: Breydo L
Year: 2007
Journal: Biochemistry
Title: Nonpolar substitution at the C-terminus of the prion protein, a mimic of the glycosylphosphatidylinositol anchor, partially impairs amyloid fibril formation.
Volume: 46
Issue: 3
Pages: 852-61
Publication
First Author: Mitchell DA
Year: 2007
Journal: Mol Immunol
Title: Prion protein activates and fixes complement directly via the classical pathway: implications for the mechanism of scrapie agent propagation in lymphoid tissue.
Volume: 44
Issue: 11
Pages: 2997-3004
Publication
First Author: Vella LJ
Year: 2007
Journal: J Pathol
Title: Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
Volume: 211
Issue: 5
Pages: 582-90
Publication
First Author: Watt NT
Year: 2007
Journal: Free Radic Biol Med
Title: Cellular prion protein protects against reactive-oxygen-species-induced DNA damage.
Volume: 43
Issue: 6
Pages: 959-67
Publication
First Author: Sakudo A
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Octapeptide repeat region of prion protein (PrP) is required at an early stage for production of abnormal prion protein in PrP-deficient neuronal cell line.
Volume: 365
Issue: 1
Pages: 164-9
Publication
First Author: Lee KS
Year: 2007
Journal: J Biol Chem
Title: Hemin interactions and alterations of the subcellular localization of prion protein.
Volume: 282
Issue: 50
Pages: 36525-33
Publication
First Author: Erlich P
Year: 2008
Journal: Biochem Biophys Res Commun
Title: PrP N-terminal domain triggers PrP(Sc)-like aggregation of Dpl.
Volume: 365
Issue: 3
Pages: 478-83
Publication
First Author: Klewpatinond M
Year: 2008
Journal: J Biol Chem
Title: Deconvoluting the Cu2+ binding modes of full-length prion protein.
Volume: 283
Issue: 4
Pages: 1870-81
Publication
First Author: Khalili-Shirazi A
Year: 2007
Journal: Biochim Biophys Acta
Title: Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.
Volume: 1774
Issue: 11
Pages: 1438-50
Publication
First Author: Oglecka K
Year: 2008
Journal: Biochim Biophys Acta
Title: Relevance of the N-terminal NLS-like sequence of the prion protein for membrane perturbation effects.
Volume: 1778
Issue: 1
Pages: 206-13
Publication
First Author: Ikeda S
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Thr but Asn of the N-glycosylation sites of PrP is indispensable for its misfolding.
Volume: 369
Issue: 4
Pages: 1195-8
Publication
First Author: Sanghera N
Year: 2008
Journal: Biochim Biophys Acta
Title: Globular and pre-fibrillar prion aggregates are toxic to neuronal cells and perturb their electrophysiology.
Volume: 1784
Issue: 6
Pages: 873-81
Publication
First Author: Thaa B
Year: 2008
Journal: Biochim Biophys Acta
Title: The deletion of amino acids 114-121 in the TM1 domain of mouse prion protein stabilizes its conformation but does not affect the overall structure.
Volume: 1783
Issue: 6
Pages: 1076-84
Publication
First Author: Brazier MW
Year: 2008
Journal: J Biol Chem
Title: Manganese binding to the prion protein.
Volume: 283
Issue: 19
Pages: 12831-9
Publication
First Author: Rambold AS
Year: 2008
Journal: EMBO J
Title: Stress-protective signalling of prion protein is corrupted by scrapie prions.
Volume: 27
Issue: 14
Pages: 1974-84
Publication
First Author: White MD
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease.
Volume: 105
Issue: 29
Pages: 10238-43
Publication
First Author: Rane NS
Year: 2008
Journal: Dev Cell
Title: Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration.
Volume: 15
Issue: 3
Pages: 359-70
Publication
First Author: Canello T
Year: 2008
Journal: Biochemistry
Title: Methionine sulfoxides on PrPSc: a prion-specific covalent signature.
Volume: 47
Issue: 34
Pages: 8866-73
Publication
First Author: Oh JM
Year: 2008
Journal: Mol Cell Neurosci
Title: The involvement of cellular prion protein in the autophagy pathway in neuronal cells.
Volume: 39
Issue: 2
Pages: 238-47
Publication
First Author: Christensen HM
Year: 2009
Journal: J Neurochem
Title: A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells.
Volume: 108
Issue: 1
Pages: 44-56
Publication
First Author: Yamaguchi K
Year: 2008
Journal: Biochemistry
Title: Critical region for amyloid fibril formation of mouse prion protein: unusual amyloidogenic properties of the helix 2 peptide.
Volume: 47
Issue: 50
Pages: 13242-51
Publication
First Author: Walmsley AR
Year: 2009
Journal: Mol Cell Neurosci
Title: alpha-cleavage of the prion protein occurs in a late compartment of the secretory pathway and is independent of lipid rafts.
Volume: 40
Issue: 2
Pages: 242-8
Publication
First Author: Sasaki K
Year: 2009
Journal: J Pathol
Title: Development of oligomeric prion-protein aggregates in a mouse model of prion disease.
Volume: 219
Issue: 1
Pages: 123-30
Publication
First Author: Wang F
Year: 2010
Journal: Science
Title: Generating a prion with bacterially expressed recombinant prion protein.
Volume: 327
Issue: 5969
Pages: 1132-5
Publication
First Author: Edgeworth JA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous generation of mammalian prions.
Volume: 107
Issue: 32
Pages: 14402-6
Publication
First Author: Sun Y
Year: 2008
Journal: J Mol Biol
Title: Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size.
Volume: 376
Issue: 4
Pages: 1155-67
Publication
First Author: Jain S
Year: 2008
Journal: J Mol Biol
Title: Evidence for stepwise formation of amyloid fibrils by the mouse prion protein.
Volume: 382
Issue: 5
Pages: 1228-41
Publication
First Author: Haigh CL
Year: 2011
Journal: Free Radic Biol Med
Title: Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro.
Volume: 51
Issue: 3
Pages: 594-608
Publication
First Author: Pathmajeyan MS
Year: 2011
Journal: Glia
Title: Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro.
Volume: 59
Issue: 11
Pages: 1684-94
Publication
First Author: Sigurdson CJ
Year: 2011
Journal: J Neurosci
Title: Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein.
Volume: 31
Issue: 39
Pages: 13840-7
Publication
First Author: Puig B
Year: 2011
Journal: PLoS One
Title: N-glycans and glycosylphosphatidylinositol-anchor act on polarized sorting of mouse PrP(C) in Madin-Darby canine kidney cells.
Volume: 6
Issue: 9
Pages: e24624
Publication
First Author: Davies P
Year: 2011
Journal: Biochemistry
Title: Contribution of individual histidines to prion protein copper binding.
Volume: 50
Issue: 50
Pages: 10781-91
Publication
First Author: Perez-Pineiro R
Year: 2011
Journal: FEBS J
Title: The prion protein binds thiamine.
Volume: 278
Issue: 21
Pages: 4002-14
Publication
First Author: Christen B
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural plasticity of the cellular prion protein and implications in health and disease.
Volume: 110
Issue: 21
Pages: 8549-54
Publication
First Author: Singh J
Year: 2012
Journal: J Mol Biol
Title: Development of the structural core and of conformational heterogeneity during the conversion of oligomers of the mouse prion protein to worm-like amyloid fibrils.
Volume: 423
Issue: 2
Pages: 217-31
Publication
First Author: Rouvinski A
Year: 2014
Journal: J Cell Biol
Title: Live imaging of prions reveals nascent PrPSc in cell-surface, raft-associated amyloid strings and webs.
Volume: 204
Issue: 3
Pages: 423-41
Publication
First Author: Bate C
Year: 2016
Journal: J Biol Chem
Title: Sialic Acid on the Glycosylphosphatidylinositol Anchor Regulates PrP-mediated Cell Signaling and Prion Formation.
Volume: 291
Issue: 1
Pages: 160-70
Publication
First Author: Dametto P
Year: 2015
Journal: PLoS One
Title: Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP.
Volume: 10
Issue: 2
Pages: e0117412
Publication
First Author: Falker C
Year: 2016
Journal: J Neurochem
Title: Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.
Volume: 137
Issue: 1
Pages: 88-100
Publication
First Author: Makarava N
Year: 2016
Journal: Am J Pathol
Title: New Molecular Insight into Mechanism of Evolution of Mammalian Synthetic Prions.
Volume: 186
Issue: 4
Pages: 1006-14
Publication
First Author: Munoz-Montesino C
Year: 2016
Journal: J Virol
Title: Generating Bona Fide Mammalian Prions with Internal Deletions.
Volume: 90
Issue: 15
Pages: 6963-75
Publication
First Author: Herbst A
Year: 2013
Journal: PLoS Pathog
Title: Infectious prions accumulate to high levels in non proliferative C2C12 myotubes.
Volume: 9
Issue: 11
Pages: e1003755
Publication
First Author: Neuendorf E
Year: 2004
Journal: J Biol Chem
Title: Glycosylation deficiency at either one of the two glycan attachment sites of cellular prion protein preserves susceptibility to bovine spongiform encephalopathy and scrapie infections.
Volume: 279
Issue: 51
Pages: 53306-16
Publication
First Author: Fang S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: The retention of prion protein in the endoplasmic reticulum prevents N2A cells from proteasome inhibition-induced cytotoxicity.
Volume: 491
Issue: 2
Pages: 500-507