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Search results 501 to 600 out of 3238 for Psen1

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Type Details Score
Publication
30215697 | J:266861
First Author: Lei Y
Year: 2018
Journal: Endocrinology
Title: Effects of Androgens on the Amyloid-β Protein in Alzheimer's Disease.
Volume: 159
Issue: 12
Pages: 3885-3894
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36242849 | J:358338
 
First Author: Kim S
Year: 2022
Journal: Biomed Pharmacother
Title: Dual modulators of aggregation and dissociation of amyloid beta and tau: In vitro, in vivo, and in silico studies of Uncaria rhynchophylla and its bioactive components.
Volume: 156
Pages: 113865
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Publication
21741995 | J:175693
First Author: Cassano T
Year: 2011
Journal: Behav Brain Res
Title: Olfactory memory is impaired in a triple transgenic model of Alzheimer disease.
Volume: 224
Issue: 2
Pages: 408-12
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Publication
20231471 | J:159326
First Author: Wang JM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease.
Volume: 107
Issue: 14
Pages: 6498-503
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Publication
25857617 | J:230543
First Author: Mota SI
Year: 2015
Journal: Biochim Biophys Acta
Title: Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.
Volume: 1852
Issue: 7
Pages: 1428-41
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Publication
25046994 | J:218348
 
First Author: Kazim SF
Year: 2014
Journal: Neurobiol Dis
Title: Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease.
Volume: 71
Pages: 110-30
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Publication
36303870 | J:331557
 
First Author: Farkas S
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Ovariectomy-induced hormone deprivation aggravates Aβ(1-42) deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer's disease.
Volume: 13
Pages: 985424
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Publication
28771492 | J:248320
First Author: Montoliu-Gaya L
Year: 2017
Journal: PLoS One
Title: Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effect.
Volume: 12
Issue: 8
Pages: e0181480
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Publication
17306982 | J:134857
First Author: Halagappa VK
Year: 2007
Journal: Neurobiol Dis
Title: Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
Volume: 26
Issue: 1
Pages: 212-20
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Publication
26362250 | J:226489
First Author: Smith PY
Year: 2015
Journal: Hum Mol Genet
Title: miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Volume: 24
Issue: 23
Pages: 6721-35
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Publication
24236177 | J:209208
First Author: Attar A
Year: 2013
Journal: PLoS One
Title: A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease.
Volume: 8
Issue: 11
Pages: e80355
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Publication
39264364 | J:359098
   
First Author: Michaud F
Year: 2024
Journal: Elife
Title: Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer's disease.
Volume: 13
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Publication
30870531 | J:284854
First Author: De Chiara G
Year: 2019
Journal: PLoS Pathog
Title: Recurrent herpes simplex virus-1 infection induces hallmarks of neurodegeneration and cognitive deficits in mice.
Volume: 15
Issue: 3
Pages: e1007617
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Publication
23071606 | J:192092
First Author: Rabinovich-Nikitin I
Year: 2012
Journal: PLoS One
Title: Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice.
Volume: 7
Issue: 10
Pages: e46650
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Publication
34680482 | J:328280
 
First Author: Castillo-Mariqueo L
Year: 2021
Journal: Biomedicines
Title: Modeling Functional Limitations, Gait Impairments, and Muscle Pathology in Alzheimer's Disease: Studies in the 3xTg-AD Mice.
Volume: 9
Issue: 10
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Publication
33634105 | J:314045
 
First Author: Chen C
Year: 2020
Journal: Front Cell Dev Biol
Title: Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease.
Volume: 8
Pages: 624339
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28575011 | J:247319
First Author: Christensen A
Year: 2017
Journal: PLoS One
Title: Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice.
Volume: 12
Issue: 6
Pages: e0178490
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Publication
35377002 | J:350410
First Author: Marcatti M
Year: 2022
Journal: Cell Mol Life Sci
Title: Aβ/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer's disease.
Volume: 79
Issue: 4
Pages: 222
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29331876 | J:262423
 
First Author: Bignante EA
Year: 2018
Journal: Neurobiol Aging
Title: APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models.
Volume: 64
Pages: 44-57
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Publication
31521745 | J:291312
 
First Author: Young ML
Year: 2019
Journal: Mol Cell Neurosci
Title: The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice.
Volume: 101
Pages: 103409
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Publication
30816415 | J:279236
First Author: Chiquita S
Year: 2019
Journal: Hum Mol Genet
Title: A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss.
Volume: 28
Issue: 13
Pages: 2174-2188
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Publication
39516200 | J:358356
First Author: Blankenship HE
Year: 2024
Journal: Nat Commun
Title: VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction.
Volume: 15
Issue: 1
Pages: 9673
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Publication
31381841 | J:291308
First Author: Li Puma DD
Year: 2019
Journal: Stem Cells
Title: Herpes Simplex Virus Type-1 Infection Impairs Adult Hippocampal Neurogenesis via Amyloid-β Protein Accumulation.
Volume: 37
Issue: 11
Pages: 1467-1480
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Publication
37465526 | J:346981
 
First Author: Choudhury N
Year: 2023
Journal: Front Pharmacol
Title: Hyperactivity of medial prefrontal cortex pyramidal neurons occurs in a mouse model of early-stage Alzheimer's disease without β-amyloid accumulation.
Volume: 14
Pages: 1194869
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Publication
25024345 | J:351730
First Author: O'Bryant SE
Year: 2014
Journal: J Alzheimers Dis
Title: Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues.
Volume: 42
Issue: 4
Pages: 1325-35
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Publication
31276749 | J:291314
 
First Author: Gali CC
Year: 2019
Journal: Mol Cell Neurosci
Title: Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Volume: 99
Pages: 103390
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Publication
32651315 | J:348439
First Author: Hakim MA
Year: 2020
Journal: J Alzheimers Dis
Title: Development of Alzheimer's Disease Progressively Alters Sex-Dependent KCa and Sex-Independent KIR Channel Function in Cerebrovascular Endothelium.
Volume: 76
Issue: 4
Pages: 1423-1442
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Publication
27276998 | J:358333
 
First Author: Xu J
Year: 2016
Journal: Sci Rep
Title: Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.
Volume: 6
Pages: 27524
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Publication
27077851 | J:351765
First Author: Shen L
Year: 2016
Journal: Int J Mol Sci
Title: Redox Proteomic Profiling of Specifically Carbonylated Proteins in the Serum of Triple Transgenic Alzheimer's Disease Mice.
Volume: 17
Issue: 4
Pages: 469
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Publication
30282635 | J:358334
First Author: Murphy K
Year: 2018
Journal: J Biol Chem
Title: Mini-GAGR, an intranasally applied polysaccharide, activates the neuronal Nrf2-mediated antioxidant defense system.
Volume: 293
Issue: 47
Pages: 18242-18269
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Publication
36610160 | J:351745
 
First Author: He Z
Year: 2023
Journal: Phytomedicine
Title: The protective effects of Esculentoside A through AMPK in the triple transgenic mouse model of Alzheimer's disease.
Volume: 109
Pages: 154555
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Publication
23056194 | J:192107
First Author: Adebakin A
Year: 2012
Journal: PLoS One
Title: Impaired satiation and increased feeding behaviour in the triple-transgenic Alzheimer's disease mouse model.
Volume: 7
Issue: 10
Pages: e45179
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Publication
31803044 | J:358331
 
First Author: Liu Y
Year: 2019
Journal: Front Aging Neurosci
Title: Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice.
Volume: 11
Pages: 309
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Publication
33536883 | J:358336
 
First Author: Gimenez-Llort L
Year: 2020
Journal: Front Behav Neurosci
Title: Digging Signatures in 13-Month-Old 3xTg-AD Mice for Alzheimer's Disease and Its Disruption by Isolation Despite Social Life Since They Were Born.
Volume: 14
Pages: 611384
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Publication
34856352 | J:358335
 
First Author: Duncan MJ
Year: 2022
Journal: Neuroscience
Title: Chronic Fragmentation of the Daily Sleep-Wake Rhythm Increases Amyloid-beta Levels and Neuroinflammation in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 481
Pages: 111-122
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Publication
23711927 | J:199110
 
First Author: Blaney CE
Year: 2013
Journal: Behav Brain Res
Title: Maternal genotype influences behavioral development of 3×Tg-AD mouse pups.
Volume: 252
Pages: 40-8
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Publication
20798886 | J:284909
   
First Author: Oh KJ
Year: 2010
Journal: Int J Alzheimers Dis
Title: Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.
Volume: 2010
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Publication
34025387 | J:348449
 
First Author: Zeng M
Year: 2021
Journal: Front Aging Neurosci
Title: Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
Volume: 13
Pages: 628860
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Publication
30454039 | J:284849
First Author: Rosenberg RN
Year: 2018
Journal: Alzheimers Res Ther
Title: Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology.
Volume: 10
Issue: 1
Pages: 115
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Publication
31733664 | J:284862
 
First Author: Hoffman JL
Year: 2019
Journal: Int Rev Neurobiol
Title: Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 148
Pages: 169-230
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Publication
22688056 | J:186995
First Author: Medeiros R
Year: 2012
Journal: Am J Pathol
Title: Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice.
Volume: 181
Issue: 2
Pages: 616-25
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Publication
35151213 | J:351778
 
First Author: He Z
Year: 2022
Journal: Phytomedicine
Title: Esculentoside A alleviates cognitive deficits and amyloid pathology through peroxisome proliferator-activated receptor γ-dependent mechanism in an Alzheimer's disease model.
Volume: 98
Pages: 153956
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Publication
30980800 | J:277219
First Author: Fertan E
Year: 2019
Journal: Am J Pathol
Title: Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease.
Volume: 189
Issue: 7
Pages: 1435-1450
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Publication
36576642 | J:351795
First Author: Ballesteros-Álvarez J
Year: 2023
Journal: Geroscience
Title: Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease.
Volume: 45
Issue: 2
Pages: 1095-1113
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Publication
31927145 | J:297590
 
First Author: Imamura T
Year: 2020
Journal: Neurobiol Dis
Title: Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
Volume: 137
Pages: 104739
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Publication
31596896 | J:280799
First Author: Muñoz-Cabrera JM
Year: 2019
Journal: PLoS One
Title: Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease.
Volume: 14
Issue: 10
Pages: e0223578
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Publication
20807511 | J:166622
 
First Author: Rosario ER
Year: 2010
Journal: Brain Res
Title: Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways.
Volume: 1359
Pages: 281-90
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Publication
35853553 | J:351735
 
First Author: Diaz-Amarilla P
Year: 2022
Journal: Neurochem Int
Title: Isolation and characterization of neurotoxic astrocytes derived from adult triple transgenic Alzheimer's disease mice.
Volume: 159
Pages: 105403
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Publication
35719714 | J:351734
First Author: Hu W
Year: 2022
Journal: J Alzheimers Dis Rep
Title: Heightened Tameness and Accelerated Handling-Habituation in 3×Tg-AD Mice on a B6;129 Genetic Background.
Volume: 6
Issue: 1
Pages: 245-255
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Publication
33753066 | J:306942
 
First Author: Pairojana T
Year: 2021
Journal: Brain Res
Title: Age and gender differences for the behavioral phenotypes of 3xTg alzheimer's disease mice.
Volume: 1762
Pages: 147437
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Publication
30031227 | J:348501
First Author: Tramutola A
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.
Volume: 1864
Issue: 10
Pages: 3309-3321
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Publication
33621639 | J:311340
 
First Author: Santos-Gil DF
Year: 2021
Journal: Neurosci Lett
Title: Retinoid X receptor activation promotes re-myelination in a very old triple transgenic mouse model of Alzheimer's disease.
Volume: 750
Pages: 135764
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33757765 | J:311341
 
First Author: Neves AF
Year: 2021
Journal: Exp Neurol
Title: Intravenous administration of mesenchymal stem cells reduces Tau phosphorylation and inflammation in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 341
Pages: 113706
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Publication
32816243 | J:311336
First Author: Ochi S
Year: 2020
Journal: Mol Neurobiol
Title: Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice.
Volume: 57
Issue: 12
Pages: 4941-4951
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33417228 | J:311337
First Author: Fonar G
Year: 2021
Journal: Mol Neurobiol
Title: Modified Snake α-Neurotoxin Averts β-Amyloid Binding to α7 Nicotinic Acetylcholine Receptor and Reverses Cognitive Deficits in Alzheimer's Disease Mice.
Volume: 58
Issue: 5
Pages: 2322-2341
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Publication
34265307 | J:311331
First Author: Valverde A
Year: 2021
Journal: J Biol Chem
Title: Dipeptidyl peptidase 4 contributes to Alzheimer's disease-like defects in a mouse model and is increased in sporadic Alzheimer's disease brains.
Volume: 297
Issue: 2
Pages: 100963
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Publication
29067327 | J:351697
First Author: Lee MH
Year: 2017
Journal: Alzheimers Dement (N Y)
Title: Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.
Volume: 3
Issue: 2
Pages: 189-204
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Publication
36038084 | J:350491
 
First Author: Tousley AR
Year: 2023
Journal: Alcohol
Title: Precocious emergence of cognitive and synaptic dysfunction in 3xTg-AD mice exposed prenatally to ethanol.
Volume: 107
Pages: 56-72
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Publication
36681141 | J:348508
 
First Author: Chen J
Year: 2023
Journal: Neuroscience
Title: Exercise Protects Against Cognitive Injury and Inflammation in Alzheimer's Disease Through Elevating miR-148a-3p.
Volume: 513
Pages: 126-133
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Publication
33058355 | J:311325
First Author: Zhang Y
Year: 2020
Journal: FASEB J
Title: Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease.
Volume: 34
Issue: 12
Pages: 16364-16382
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Publication
36241022 | J:348507
 
First Author: Valle ML
Year: 2022
Journal: Mol Cell Neurosci
Title: Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology.
Volume: 123
Pages: 103785
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Publication
18468702 | J:136980
First Author: Pietropaolo S
Year: 2008
Journal: Behav Brain Res
Title: The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective.
Volume: 192
Issue: 1
Pages: 42-60
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34483889 | J:311359
 
First Author: Winslow W
Year: 2021
Journal: Front Aging Neurosci
Title: IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer's Disease Associated With Brain Weight.
Volume: 13
Pages: 720214
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Publication
34087256 | J:311360
 
First Author: Wang C
Year: 2021
Journal: Behav Brain Res
Title: Chronic sleep deprivation exacerbates cognitive and synaptic plasticity impairments in APP/PS1 transgenic mice.
Volume: 412
Pages: 113400
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Publication
29073110 | J:255228
First Author: Volmar CH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.
Volume: 114
Issue: 43
Pages: E9135-E9144
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Publication
31325514 | J:352846
 
First Author: Kim D
Year: 2019
Journal: Behav Brain Res
Title: Protective effect of exercise training against the progression of Alzheimer's disease in 3xTg-AD mice.
Volume: 374
Pages: 112105
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Publication
20937383 | J:168651
First Author: Perez SE
Year: 2011
Journal: Neurobiol Dis
Title: Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice.
Volume: 41
Issue: 2
Pages: 338-52
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Publication
32384696 | J:349554
 
First Author: Kim TW
Year: 2020
Journal: Int J Mol Sci
Title: Infusion of Plasma from Exercised Mice Ameliorates Cognitive Dysfunction by Increasing Hippocampal Neuroplasticity and Mitochondrial Functions in 3xTg-AD Mice.
Volume: 21
Issue: 9
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Publication
36577656 | J:348513
First Author: Hakim MA
Year: 2023
Journal: Microcirculation
Title: K(IR) channel regulation of electrical conduction along cerebrovascular endothelium: Enhanced modulation during Alzheimer's disease.
Volume: 30
Issue: 1
Pages: e12797
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Publication
31900170 | J:352858
First Author: Liu Y
Year: 2020
Journal: J Neuroinflammation
Title: Short-term resistance exercise inhibits neuroinflammation and attenuates neuropathological changes in 3xTg Alzheimer's disease mice.
Volume: 17
Issue: 1
Pages: 4
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Publication
35599482 | J:350538
First Author: Frame G
Year: 2022
Journal: J Alzheimers Dis
Title: Alterations in Retinal Signaling Across Age and Sex in 3xTg Alzheimer's Disease Mice.
Volume: 88
Issue: 2
Pages: 471-492
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17169464 | J:135054
First Author: Boeras DI
Year: 2008
Journal: Neurobiol Aging
Title: Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy.
Volume: 29
Issue: 3
Pages: 319-28
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30478329 | J:269715
First Author: Baek H
Year: 2018
Journal: Sci Rep
Title: Bee venom phospholipase A2 ameliorates Alzheimer's disease pathology in Aβ vaccination treatment without inducing neuro-inflammation in a 3xTg-AD mouse model.
Volume: 8
Issue: 1
Pages: 17369
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32470367 | J:321329
First Author: Benthem SD
Year: 2020
Journal: Curr Biol
Title: Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer's Disease.
Volume: 30
Issue: 13
Pages: 2588-2601.e5
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Publication
29213096 | J:287381
First Author: Rajamohamedsait H
Year: 2017
Journal: Sci Rep
Title: Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.
Volume: 7
Issue: 1
Pages: 17034
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Publication
29215028 | J:287391
First Author: Lauretti E
Year: 2017
Journal: Sci Rep
Title: Effect of canola oil consumption on memory, synapse and neuropathology in the triple transgenic mouse model of Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 17134
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Publication
28115709 | J:264939
First Author: Netzer WJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage.
Volume: 114
Issue: 6
Pages: 1389-1394
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Publication
30927734 | J:352869
 
First Author: vonderEmbse AN
Year: 2019
Journal: Int Immunopharmacol
Title: Dysfunctional microglia:neuron interactions with significant female bias in a developmental gene x environment rodent model of Alzheimer's disease.
Volume: 71
Pages: 241-250
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Publication
20726889 | J:171776
First Author: Hamilton LK
Year: 2010
Journal: Eur J Neurosci
Title: Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease.
Volume: 32
Issue: 6
Pages: 905-20
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Publication
35448465 | J:350534
 
First Author: Guzzardi MA
Year: 2022
Journal: Metabolites
Title: Liver and White/Brown Fat Dystrophy Associates with Gut Microbiota and Metabolomic Alterations in 3xTg Alzheimer's Disease Mouse Model.
Volume: 12
Issue: 4
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Publication
31570577 | J:280407
First Author: Martini AC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta impairs TOM1-mediated IL-1R1 signaling.
Volume: 116
Issue: 42
Pages: 21198-21206
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Publication
22035587 | J:188184
First Author: Cassano T
Year: 2012
Journal: Neurobiol Aging
Title: Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease.
Volume: 33
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