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Search results 501 to 600 out of 689 for Ptpn11

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Type Details Score
Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Pathway
R-MMU-8865999 | MET activates PTPN11
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Allele
Tg(Myh7-Ptpn11*Q79R)11Rbns | MGI:3822132
Name: transgene insertion 11, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-cat,-Ptpn11*Q97R)1Rbns | MGI:3822129
Name: transgene insertion 1, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh7-Ptpn11*Q79R)11Rbns/?
Background: FVB.Cg-Tg(Myh7-Ptpn11*Q79R)11Rbns
Zygosity: ot
Has Mutant Allele: true
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Interaction Experiment
Araki T (2004)
Description: Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
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Allele
Ptpn11<tm1Paw> | MGI:2176524
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Anthony Pawson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ptpn11<tm1Rbn> | MGI:2176526
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Daniel U Rabin
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ptpn11<tm1Bgn> | MGI:3050284
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Benjamin G Neel
Allele Type: Targeted
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: H2az2/H2az2<+> Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/?
Background: involves: C57BL/6J * CBA/J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/? Tg(Tek-cre)12Flv/?
Background: involves: C3H * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Transgene
MGI:3822047 | Tg(CAG-cat,-Ptpn11*Q97R)1Rbns
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3822031 | Tg(Myh7-Ptpn11*Q79R)11Rbns
Type: transgene
Organism: mouse, laboratory
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Allele
Ptpn11<tm6Bgn> | MGI:3840248
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 6, Benjamin Neel
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Ptpn11/Ptpn11<+>
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptpn11/Ptpn11
Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptpn11/Ptpn11
Background: involves: 129 * Black Swiss
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptpn11/Ptpn11<+>
Background: involves: 129 * Black Swiss
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0060578 | Noonan syndrome 1
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Genotype
Genotype
Symbol: Emx1/Emx1<+> Ptpn11/Ptpn11<+>
Background: B6.129S-Ptpn11 Emx1
Zygosity: cn
Has Mutant Allele: true
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DO Term
DOID:0080548 | Noonan syndrome with multiple lentigines 1
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Publication
29085371 | J:312836
 
First Author: Miah SMS
Year: 2017
Journal: Front Immunol
Title: Ptpn11 Deletion in CD4+ Cells Does Not Affect T Cell Development and Functions but Causes Cartilage Tumors in a T Cell-Independent Manner.
Volume: 8
Pages: 1326
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DO Term
DOID:0111512 | metachondromatosis
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Allele
Tg(Myh6-Ptpn11)75Rbns | MGI:3822134
Name: transgene insertion 75, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Myh7-Ptpn11)294Rbns | MGI:3822135
Name: transgene insertion 294, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-cat,-Ptpn11)1Rbns | MGI:3822130
Name: transgene insertion 1, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3822195 | FVB.Cg-Tg(Myh6-Ptpn11)75Rbns
Attribute String: transgenic
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Strain
MGI:3822198 | FVB.Cg-Tg(Myh7-Ptpn11)294Rbns
Attribute String: transgenic
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Genotype
Genotype
Symbol: Tg(Myh6-Ptpn11)75Rbns/?
Background: FVB.Cg-Tg(Myh6-Ptpn11)75Rbns
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh7-Ptpn11)294Rbns/?
Background: FVB.Cg-Tg(Myh7-Ptpn11)294Rbns
Zygosity: ot
Has Mutant Allele: true
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Allele
Tg(Myh6-Ptpn11*Q79R)197Rbns | MGI:3822133
Name: transgene insertion 197, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Myh6-Ptpn11*Q510E)#Krnz | MGI:5909086
Name: transgene insertion, Maike Krenz
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
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Protein Coding Gene
MGI:96079 | Hgf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96969 | Met
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q08048
Organism: Mus musculus/domesticus
Length: 728  
Fragment?: false
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Protein
P16056
Organism: Mus musculus/domesticus
Length: 1379  
Fragment?: false
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Allele
Il6st<tm1Ern> | MGI:2388478
Name: interleukin 6 signal transducer; targeted mutation 1, Matthias Ernst
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6332159 | STOCK IL6st<tm1Ern>/LudApb
Attribute String: targeted mutation, mutant stock
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Publication
25088199 | J:222534
First Author: Kurklu B
Year: 2015
Journal: Oncogene
Title: Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer.
Volume: 34
Issue: 22
Pages: 2856-66
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Publication
21606248 | J:175946
First Author: Silver JS
Year: 2011
Journal: J Immunol
Title: IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.
Volume: 187
Issue: 1
Pages: 350-60
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Publication
20062084 | J:160391
First Author: Mejías-Luque R
Year: 2010
Journal: Oncogene
Title: Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors.
Volume: 29
Issue: 12
Pages: 1753-62
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Publication
27503072 | J:236610
First Author: Atapattu L
Year: 2016
Journal: J Exp Med
Title: An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
Volume: 213
Issue: 9
Pages: 1741-57
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Publication
24804649 | J:217366
First Author: Judd LM
Year: 2014
Journal: PLoS One
Title: Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo.
Volume: 9
Issue: 5
Pages: e95993
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Publication
22140267 | J:181522
First Author: Traum D
Year: 2012
Journal: J Leukoc Biol
Title: IL-10-induced gp130 expression in mouse mast cells permits IL-6 trans-signaling.
Volume: 91
Issue: 3
Pages: 427-35
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Publication
25528766 | J:309252
First Author: Buzzelli JN
Year: 2015
Journal: Oncotarget
Title: IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment.
Volume: 6
Issue: 2
Pages: 679-95
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Publication
23728346 | J:212589
First Author: Kennedy CL
Year: 2014
Journal: Oncogene
Title: Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis.
Volume: 33
Issue: 19
Pages: 2540-6
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Publication
14699500 | J:87206
First Author: Judd LM
Year: 2004
Journal: Gastroenterology
Title: Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.
Volume: 126
Issue: 1
Pages: 196-207
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Strain
MGI:3822194 | FVB.Cg-Tg(Myh7-Ptpn11*Q79R)11Rbns
Attribute String: transgenic
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Strain
MGI:3822193 | FVB.Cg-Tg(Myh6-Ptpn11*Q79R)197Rbns
Attribute String: transgenic
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Allele
Tg(tetO-PTPN11*E76K)#Jiwu | MGI:5688299
Name: transgene insertion, Jie Wu
Allele Type: Transgenic
Attribute String: Constitutively active, Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(CAG-cat,-Ptpn11*Q510E)#Krnz | MGI:5828597
Name: transgene insertion, Maike Krenz
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Tg(Myh7-Ptpn11*Q510E)#Krnz | MGI:5909085
Name: transgene insertion, Maike Krenz
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
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Strain
MGI:5909089 | FVB/N-Tg(Myh6-Ptpn11*Q510E)#Krnz
Attribute String: transgenic, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Tg(Myh6-Ptpn11*Q79R)197Rbns/?
Background: FVB.Cg-Tg(Myh6-Ptpn11*Q79R)197Rbns
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il6st/Il6st
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il6st/Il6st
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-Ptpn11*Q510E)#Krnz/?
Background: FVB/N-Tg(Myh6-Ptpn11*Q510E)#Krnz
Zygosity: ot
Has Mutant Allele: true
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Protein Coding Gene
MGI:108088 | Gab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9QYY0
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: false
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HT Experiment
GSE87104 | RNA-seq Analysis of Wild Type and Ptpn11-deficient cerebellar Transcriptomes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6331991 | B6;129-Il6st<tm1Ern> Stat1<Rds>/MarpApb
Attribute String: mutant strain, targeted mutation
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Strain
MGI:6332144 | STOCK Il6st<tm1Ern> Stat3<tm1Aki>/LudApb
Attribute String: mutant stock, targeted mutation
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Publication
17030178 | J:117025
First Author: Judd LM
Year: 2006
Journal: Gastroenterology
Title: STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis.
Volume: 131
Issue: 4
Pages: 1073-85
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Publication
24727895 | J:221281
First Author: Miller A
Year: 2015
Journal: Oncogene
Title: Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.
Volume: 34
Issue: 12
Pages: 1510-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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