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Search results 501 to 600 out of 1306 for Rad51

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Type Details Score
Publication
First Author: Takemoto K
Year: 2020
Journal: Cell Rep
Title: Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination.
Volume: 31
Issue: 8
Pages: 107686
Publication
First Author: Matsuzaki K
Year: 2019
Journal: Nat Commun
Title: Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase.
Volume: 10
Issue: 1
Pages: 1407
Protein
Organism: Mus musculus/domesticus
Length: 976  
Fragment?: false
Protein Domain
Type: Domain
Description: This motif interacts with RAD51, a protein that plays an important role in mitotic and meiotic recombination, and in DNA repair []. This motif is found C-terminal in RAD51-associated protein 1 (RAD51AP1) and 2 (RAD51AP2).
Publication
First Author: Yokoyama H
Year: 2003
Journal: J Biol Chem
Title: Holliday junction binding activity of the human Rad51B protein.
Volume: 278
Issue: 4
Pages: 2767-72
Publication
First Author: Osakabe K
Year: 2005
Journal: Plant Mol Biol
Title: Arabidopsis Rad51B is important for double-strand DNA breaks repair in somatic cells.
Volume: 57
Issue: 6
Pages: 819-33
Protein Domain
Type: Family
Description: DNA repair protein RAD51 homologue 2 (also known as RAD51B) is a Rad51 paralogue. The Rad51 paralogues are required for homologous recombination (HR) and the maintenance of genomic stability. RAD51B is involved in the repair of double-strand DNA breaks (DSBs) via HR []. It is part of the Rad51B-Rad51C-Rad51D-XRCC2 (BCDX2) complex, which acts in the BRCA1-BRCA2-dependent HR pathway [, ]. It has DNA-dependent ATPase activity and can bind single-stranded and double-stranded DNA []. Rad51B may have a specific function in Holliday junction processing in the HR pathway [].
Publication
First Author: Bridges AE
Year: 2020
Journal: Cancer Res
Title: RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal.
Volume: 80
Issue: 18
Pages: 3855-3866
Publication
First Author: Dai J
Year: 2017
Journal: Cell Rep
Title: Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis.
Volume: 18
Issue: 6
Pages: 1383-1394
Publication
First Author: Randolph ME
Year: 2024
Journal: iScience
Title: RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma.
Volume: 27
Issue: 2
Pages: 108925
UniProt Feature
Begin: 1
Description: DNA repair protein RAD51 homolog 2
Type: chain
End: 350
UniProt Feature
Begin: 1
Description: DNA repair protein RAD51 homolog 3
Type: chain
End: 366
UniProt Feature
Begin: 1
Description: DNA repair protein RAD51 homolog 4
Type: chain
End: 329
UniProt Feature
Begin: 2
Description: DNA repair protein RAD51 homolog 1
Type: chain
End: 339
Protein
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: false
Publication
First Author: Kovalenko OV
Year: 2006
Journal: Nucleic Acids Res
Title: RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51.
Volume: 34
Issue: 18
Pages: 5081-92
Publication
First Author: Ploquin M
Year: 2007
Journal: Nucleic Acids Res
Title: Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases.
Volume: 35
Issue: 8
Pages: 2719-33
Publication
First Author: Park J
Year: 2013
Journal: Mol Cell Biol
Title: The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.
Volume: 33
Issue: 8
Pages: 1632-44
Publication
First Author: Kovalenko OV
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes.
Volume: 93
Issue: 7
Pages: 2958-63
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Zainu A
Year: 2024
Journal: Nat Commun
Title: FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading.
Volume: 15
Issue: 1
Pages: 7015
Publication
First Author: Mishra AP
Year: 2022
Journal: Nat Commun
Title: BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks.
Volume: 13
Issue: 1
Pages: 1751
Publication
First Author: Schiaffella E
Year: 1998
Journal: Immunogenetics
Title: High RAD51 mRNA levels in young rabbit appendix. A role in B-cell gene conversion?
Volume: 48
Issue: 2
Pages: 108-15
Publication  
First Author: Gao H
Year: 2019
Journal: Front Physiol
Title: Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human.
Volume: 10
Pages: 765
Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
Publication
First Author: Leasure CS
Year: 2001
Journal: Gene
Title: Sequence, chromosomal location and expression analysis of the murine homologue of human RAD51L2/RAD51C.
Volume: 271
Issue: 1
Pages: 59-67
Publication
First Author: Smiraldo PG
Year: 2005
Journal: Cancer Res
Title: Extensive chromosomal instability in Rad51d-deficient mouse cells.
Volume: 65
Issue: 6
Pages: 2089-96
Publication
First Author: Zhang Z
Year: 2018
Journal: Exp Cell Res
Title: RPA1 downregulation enhances nasopharyngeal cancer radiosensitivity via blocking RAD51 to the DNA damage site.
Volume: 371
Issue: 2
Pages: 330-341
Protein
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
Publication
First Author: Ohnishi T
Year: 1998
Journal: Biochem Biophys Res Commun
Title: In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene.
Volume: 245
Issue: 2
Pages: 319-24
Protein
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: true
Publication
First Author: Bu W
Year: 2025
Journal: Hepatology
Title: Early onset of pathological polyploidization and cellular senescence in hepatocytes lacking RAD51 creates a pro-fibrotic and pro-tumorigenic inflammatory microenvironment.
Volume: 81
Issue: 2
Pages: 491-508
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
Publication
First Author: Bhat KP
Year: 2018
Journal: Cell Rep
Title: RADX Modulates RAD51 Activity to Control Replication Fork Protection.
Volume: 24
Issue: 3
Pages: 538-545
Publication
First Author: Shu Z
Year: 1999
Journal: Mol Cell Biol
Title: Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background.
Volume: 19
Issue: 12
Pages: 8686-93
Publication
First Author: Haaf T
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.
Volume: 92
Issue: 6
Pages: 2298-302
Publication
First Author: Zhao W
Year: 2015
Journal: Nucleic Acids Res
Title: Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis.
Volume: 43
Issue: 8
Pages: 4055-66
Allele    
Name: RAD51 paralog D; wild type
Allele    
Name: RAD51 paralog B; wild type
Allele    
Name: RAD51 recombinase; wild type
Allele    
Name: RAD51 paralog C; wild type
Publication
First Author: Bridges AE
Year: 2021
Journal: Mol Cancer Res
Title: RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy.
Volume: 19
Issue: 9
Pages: 1486-1497
Interaction Experiment
Description: Domain mapping of the Rad51 paralog protein complexes.
Interaction Experiment
Description: Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation.
Publication
First Author: Dray E
Year: 2010
Journal: Nat Struct Mol Biol
Title: Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
Volume: 17
Issue: 10
Pages: 1255-9
Publication  
First Author: Sasanuma H
Year: 2013
Journal: Nat Commun
Title: A new protein complex promoting the assembly of Rad51 filaments.
Volume: 4
Pages: 1676
Protein
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
Publication
First Author: Kuznetsov SG
Year: 2009
Journal: Cancer Res
Title: Loss of Rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice.
Volume: 69
Issue: 3
Pages: 863-72
Publication
First Author: Godthelp BC
Year: 2002
Journal: Nucleic Acids Res
Title: Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability.
Volume: 30
Issue: 10
Pages: 2172-82
Publication
First Author: Kuznetsov S
Year: 2007
Journal: J Cell Biol
Title: RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.
Volume: 176
Issue: 5
Pages: 581-92
DO Term
Publication
First Author: Dungrawala H
Year: 2017
Journal: Mol Cell
Title: RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
Volume: 67
Issue: 3
Pages: 374-386.e5
Publication
First Author: Zhang XP
Year: 2005
Journal: J Biol Chem
Title: Gly-103 in the N-terminal domain of Saccharomyces cerevisiae Rad51 protein is critical for DNA binding.
Volume: 280
Issue: 28
Pages: 26303-11
Allele
Name: RAD51 recombinase; targeted mutation 1, Paul Hasty
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: RAD51 recombinase; targeted mutation 1, Takashi Morita
Allele Type: Targeted
Attribute String: Null/knockout
Allele    
Name: RAD51 associated protein 1; wild type
Allele  
Name: RAD51 associated protein 2; wild type
Allele Type: Not Specified
Allele  
Name: RAD51 recombinase; gene trap YHD303, BayGenomics
Allele Type: Gene trapped
Allele  
Name: RAD51 paralog B; gene trap RRI325, BayGenomics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST41448, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST61668, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST72759, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST113286, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST119464, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST191539, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST196282, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST226006, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST245409, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST252329, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST261978, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST274840, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST280607, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST308246, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST360843, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST375200, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST378140, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 recombinase; gene trap OST379356, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: RAD51 paralog B; gene trap RRK431, BayGenomics
Allele Type: Gene trapped
Allele
Name: RAD51 recombinase; targeted mutation 1, Changshun Shao
Allele Type: Targeted
Attribute String: Conditional ready
Publication
First Author: Tumiati M
Year: 2016
Journal: Oncogene
Title: Rad51c- and Trp53-double-mutant mouse model reveals common features of homologous recombination-deficient breast cancers.
Volume: 35
Issue: 35
Pages: 4601-10
Publication
First Author: Tumiati M
Year: 2015
Journal: J Pathol
Title: Loss of Rad51c accelerates tumourigenesis in sebaceous glands of Trp53-mutant mice.
Volume: 235
Issue: 1
Pages: 136-46
Publication
First Author: Wong AK
Year: 1997
Journal: J Biol Chem
Title: RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2.
Volume: 272
Issue: 51
Pages: 31941-4
Publication
First Author: Chen PL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.
Volume: 95
Issue: 9
Pages: 5287-92
Publication
First Author: Petukhova G
Year: 1998
Journal: Nature
Title: Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins.
Volume: 393
Issue: 6680
Pages: 91-4
Publication
First Author: Pellegrini L
Year: 2002
Journal: Nature
Title: Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.
Volume: 420
Issue: 6913
Pages: 287-93
Publication
First Author: Kovalenko OV
Year: 1997
Journal: Nucleic Acids Res
Title: A novel nucleic acid-binding protein that interacts with human rad51 recombinase.
Volume: 25
Issue: 24
Pages: 4946-53
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory