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Search results 501 to 600 out of 1044 for Rel

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Hits by Strain

Type Details Score
Publication
7767000 | J:22862
First Author: Kozak CA
Year: 1995
Journal: Mamm Genome
Title: Localization of three genes expressed in retina on mouse chromosome 11.
Volume: 6
Issue: 2
Pages: 142-4
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Publication
17431131 | J:145398
First Author: Liu XS
Year: 2007
Journal: Blood
Title: Disruption of palladin leads to defects in definitive erythropoiesis by interfering with erythroblastic island formation in mouse fetal liver.
Volume: 110
Issue: 3
Pages: 870-6
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Publication
30037996 | J:264370
First Author: Sima J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.
Volume: 115
Issue: 32
Pages: 8173-8178
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Publication
35139355 | J:324833
First Author: Simpson DS
Year: 2022
Journal: Immunity
Title: Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Volume: 55
Issue: 3
Pages: 423-441.e9
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Publication
8188294 | J:16931
First Author: Ceci JD
Year: 1994
Journal: Genomics
Title: Interspecific backcrosses provide an important new tool for centromere mapping of mouse chromosomes.
Volume: 19
Issue: 3
Pages: 515-24
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Publication
7789972 | J:23148
First Author: Avraham KB
Year: 1995
Journal: Genomics
Title: Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.
Volume: 25
Issue: 2
Pages: 388-93
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
10860829 | J:62794
First Author: Pan S
Year: 2000
Journal: Biochem Biophys Res Commun
Title: NFATz: a novel rel similarity domain containing protein.
Volume: 272
Issue: 3
Pages: 765-76
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Publication
1732739 | J:22332
First Author: Ryseck RP
Year: 1992
Journal: Mol Cell Biol
Title: RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.
Volume: 12
Issue: 2
Pages: 674-84
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Publication
2203532 | J:25020
First Author: Ghosh S
Year: 1990
Journal: Cell
Title: Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal.
Volume: 62
Issue: 5
Pages: 1019-29
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Publication
8289784 | J:113693
First Author: La Rosa FA
Year: 1994
Journal: Mol Cell Biol
Title: Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors.
Volume: 14
Issue: 2
Pages: 1039-44
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Protein Domain
IPR032397 | RHD_dimer
Type: Domain
Description: The Rel homology domain (RHD) is composed of two structural domains, an N-terminal DNA-binding domain () and a C-terminal dimerisation domain. This is the dimerisation domain [].This domain can be found in both nuclear factor of activated T cells (NFAT) and nuclear factor kappa-B (NFkB), which are RHD-containing transcription factors [].
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Publication
9597130 | J:51176
 
First Author: Ghosh S
Year: 1998
Journal: Annu Rev Immunol
Title: NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses.
Volume: 16
Pages: 225-60
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Publication
9435232 | J:45582
First Author: Tobin D
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins.
Volume: 95
Issue: 2
Pages: 565-9
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Publication
8056331 | -
First Author: Mitomo K
Year: 1994
Journal: Gene
Title: Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-kappa B in vitro.
Volume: 145
Issue: 2
Pages: 197-203
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Protein Domain
IPR030492 | RHD_CS
Type: Conserved_site
Description: Members of the Rel family share a highly conserved 300 amino acids domain termed Rel homology domain (RHD) which is located towards the amino terminus. The unique C terminus is thought to be involved in gene activation and cytoplasmic anchoring functions.For several proteins it has been demonstrated []that the Rel homology domain includes:a DNA-binding domain, which binds to the consensus DNA sequence motif5'-GGGRNNYYCC-3' (except for dorsal, which recognises the related motif5'-GRGAAAANCC-3');a dimerisation domain, which is located in the C-terminal part of theRHD;a PKA phosphorylation site (except in RelB);a nuclear localization signal (NLS), which consists of a stretch of fouror five basic residues.This entry represents a conserved site located at theN terminus of the RHD. It includes a conserved cysteine that seems tobe essential for DNA-binding in p50 [].
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Publication
27278094 | J:246885
First Author: Wu H
Year: 2016
Journal: Immunology
Title: Rel B-modified dendritic cells possess tolerogenic phenotype and functions on lupus splenic lymphocytes in vitro.
Volume: 149
Issue: 1
Pages: 48-61
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Protein
Q9WV30
Organism: Mus musculus/domesticus
Length: 1534  
Fragment?: false
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Protein Domain
IPR011539 | RHD_DNA_bind_dom
Type: Domain
Description: The Rel homology domain (RHD) is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish, NFAT, among others. The RHD is composed of two structural domains: the N-terminal DNA binding domain that is similar to that found in P53, the C-terminal domain has an immunoglobulin-like fold (See ) that functions as a dimerisation domain. This entry represents the N-terminal DNA binding domain []. Some of these transcription factors appear to form multi-protein DNA-bound complexes []. Phosphorylation of the RHD appears to play a role in the regulation of some of these transcription factors, acting to modulate the expression of their target genes []. The RHD is composed of two immunoglobulin-like β-barrel subdomains that grip the DNA in the major groove. The N-terminal specificity domain resembles the core domain of the p53 transcription factor, and contains a recognition loop that interacts with DNA bases; the C-terminal dimerisation domain contains the site for interaction with I-kappaB [].
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Protein Domain
IPR037059 | RHD_DNA_bind_dom_sf
Type: Homologous_superfamily
Description: The Rel homology domain (RHD) is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish, NFAT, among others. The RHD is composed of two structural domains: the N-terminal DNA binding domain that is similar to that found in P53, the C-terminal domain has an immunoglobulin-like fold (See ) that functions as a dimerisation domain. This entry represents the N-terminal DNA binding domain superfamily []. Some of these transcription factors appear to form multi-protein DNA-bound complexes []. Phosphorylation of the RHD appears to play a role in the regulation of some of these transcription factors, acting to modulate the expression of their target genes []. The RHD is composed of two immunoglobulin-like β-barrel subdomains that grip the DNA in the major groove. The N-terminal specificity domain resembles the core domain of the p53 transcription factor, and contains a recognition loop that interacts with DNA bases; the C-terminal dimerisation domain contains the site for interaction with I-kappaB [].
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Publication
12077338 | -
First Author: Jia S
Year: 2002
Journal: Mol Cell Biol
Title: The Dorsal Rel homology domain plays an active role in transcriptional regulation.
Volume: 22
Issue: 14
Pages: 5089-99
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Protein
Q9WV30-4
Organism: Mus musculus/domesticus
Length: 1225  
Fragment?: false
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Publication
18175145 | -
First Author: Gauthier M
Year: 2008
Journal: Dev Genes Evol
Title: The transcription factor NF-kappaB in the demosponge Amphimedon queenslandica: insights on the evolutionary origin of the Rel homology domain.
Volume: 218
Issue: 1
Pages: 23-32
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Publication
7830764 | -
First Author: Müller CW
Year: 1995
Journal: Nature
Title: Structure of the NF-kappa B p50 homodimer bound to DNA.
Volume: 373
Issue: 6512
Pages: 311-7
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Publication
9794820 | -
First Author: Wolberger C
Year: 1998
Journal: Curr Opin Genet Dev
Title: Combinatorial transcription factors.
Volume: 8
Issue: 5
Pages: 552-9
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Publication
15516339 | -
First Author: Anrather J
Year: 2005
Journal: J Biol Chem
Title: cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.
Volume: 280
Issue: 1
Pages: 244-52
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Protein
Q9WV30-3
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
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Protein
Q9WV30-2
Organism: Mus musculus/domesticus
Length: 1552  
Fragment?: false
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Publication
20876732 | -
First Author: Treiber N
Year: 2010
Journal: Genes Dev
Title: Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins.
Volume: 24
Issue: 20
Pages: 2270-5
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Publication
7876165 | -
First Author: Jain J
Year: 1995
Journal: J Biol Chem
Title: A similar DNA-binding motif in NFAT family proteins and the Rel homology region.
Volume: 270
Issue: 8
Pages: 4138-45
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Allele
Tg(Rel-luc)1Smoc | MGI:7292756
Name: transgene insertion 1, Shanghai Model Organisms Center
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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HT Experiment
E-MTAB-7470 | RNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
17869269 | -
First Author: Moorthy AK
Year: 2007
Journal: J Mol Biol
Title: X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites.
Volume: 373
Issue: 3
Pages: 723-34
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Protein
A0A0G2JGK6
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
A0A494B901
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
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Protein
Q4U113
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: false
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Protein
Q3U2V2
Organism: Mus musculus/domesticus
Length: 565  
Fragment?: false
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Protein
B5B2Q9
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
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Protein
B5B2Q8
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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Protein
Q6P3F6
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Protein
B5B2U3
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: false
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Protein
A4L9Q2
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: true
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Protein
B5B2R0
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Allele
Rel<em1Smoc> | MGI:7292008
Name: reticuloendotheliosis oncogene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429656 | C57BL/6JSmoc-Tg(Nfkb2-luc)1Smoc/Smoc
Attribute String: coisogenic, mutant strain, transgenic
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Protein
B5B2R5
Organism: Mus musculus/domesticus
Length: 673  
Fragment?: false
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Protein
A0A2I3BRX2
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
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Protein
Q8C443
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
A2AQC8
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
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Protein
B5B2R8
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q80TR0
Organism: Mus musculus/domesticus
Length: 1033  
Fragment?: true
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Protein
Q4U109
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
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Protein
A0A140LJD6
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: false
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Protein
Q4U112
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: false
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Protein
A0A140LI24
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
A0A140LI46
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
Q4U111
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Publication
10940923 | J:63950
First Author: Barton D
Year: 2000
Journal: Eur J Immunol
Title: Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis.
Volume: 30
Issue: 8
Pages: 2323-32
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Protein
Q04207
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q548Y4
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q3U3Q8
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
A0A494BA44
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q8BTL4
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
F6VCW7
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: true
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Strain
MGI:6355151 | C57BL/6JSmoc-Rel<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
Q8K120
Organism: Mus musculus/domesticus
Length: 901  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom