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Search results 501 to 564 out of 564 for Scd1

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Type Details Score
Genotype
Genotype
Symbol: Dbmc3/Dbmc3 Lep/Lep
Background: involves: BTBR * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd
Background: involves: C3H/He * C57BL/6 * YBR/Ki
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd<+>
Background: involves: C3H/He * C57BL/6 * YBR/Ki
Zygosity: ht
Has Mutant Allele: true
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Publication
17460121 | -
First Author: Gao XD
Year: 2007
Journal: Mol Biol Cell
Title: Sequential and distinct roles of the cadherin domain-containing protein Axl2p in cell polarization in yeast cell cycle.
Volume: 18
Issue: 7
Pages: 2542-60
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Publication
17581820 | -
First Author: Stahelin RV
Year: 2007
Journal: J Biol Chem
Title: Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity.
Volume: 282
Issue: 35
Pages: 25737-47
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Protein Domain
IPR035550 | Bem1/Scd2_PX
Type: Domain
Description: This entry represents the phox homology (PX) domain found in budding yeast Bem1 and fission yeast Scd2. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions such as cell signaling, vesicular trafficking, protein sorting, and lipid modification. The PX domain of Bem1 specifically binds phosphatidylinositol-4-phosphate (PI4P) [].Bem1 (Bud emergence protein 1) is involved in establishing cell polarity and morphogenesis []. It interacts with Axl2 (required for axial budding in haploid cells) and forms a complex with Cdc42, Cdc24, and Cla4 [, ]. Scd2 forms complexes with both scd1 and cdc42sp and is required for normal morphology and mating [].
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Publication
12930764 | J:119260
First Author: Lan H
Year: 2003
Journal: Genetics
Title: Dimension reduction for mapping mRNA abundance as quantitative traits.
Volume: 164
Issue: 4
Pages: 1607-14
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Publication
9159136 | J:40910
First Author: Urbánek P
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Volume: 94
Issue: 11
Pages: 5703-8
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Genotype
Genotype
Symbol: Krd/Krd<+> Pax5/Pax5
Background: involves: 129S2/SvPas * C3H/He * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd<+> Pax5/Pax5<+>
Background: involves: 129S2/SvPas * C3H/He * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
10674390 | J:59876
First Author: Parimoo S
Year: 1999
Journal: J Investig Dermatol Symp Proc
Title: Identification of a novel SCD gene and expression of the SCD gene family in mouse skin.
Volume: 4
Issue: 3
Pages: 320-2
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HT Experiment
E-GEOD-48811 | Visceral obesity in murine pregnancy
Series Id: GSE48811
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
29101357 | J:257266
First Author: Zhang M
Year: 2017
Journal: Sci Rep
Title: MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1.
Volume: 7
Issue: 1
Pages: 14493
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Publication
18852460 | J:141100
First Author: Bobrovnikova-Marjon E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.
Volume: 105
Issue: 42
Pages: 16314-9
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Publication
35624087 | J:325279
First Author: Thürmer M
Year: 2022
Journal: Nat Commun
Title: PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Volume: 13
Issue: 1
Pages: 2982
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Publication
38758779 | J:349426
First Author: Xu G
Year: 2024
Journal: Sci Adv
Title: Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease.
Volume: 10
Issue: 20
Pages: eadj5942
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Publication
24079739 | J:220416
First Author: Dahlhoff M
Year: 2013
Journal: Exp Dermatol
Title: Ligand-independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice.
Volume: 22
Issue: 10
Pages: 667-9
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Publication
32423819 | J:301739
First Author: O'Neill LM
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Global deficiency of stearoyl-CoA desaturase-2 protects against diet-induced adiposity.
Volume: 527
Issue: 3
Pages: 589-595
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Publication
24769897 | J:286524
First Author: AbuAli G
Year: 2015
Journal: Oncogene
Title: The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis.
Volume: 34
Issue: 13
Pages: 1718-28
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Publication
23671091 | J:197431
First Author: Kamphorst JJ
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.
Volume: 110
Issue: 22
Pages: 8882-7
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Publication
39153477 | J:353960
     
First Author: Yang G
Year: 2024
Journal: Neuron
Title: Spliceosomal GTPase Eftud2 deficiency-triggered ferroptosis leads to Purkinje cell degeneration.
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Publication
37852255 | J:342313
First Author: Terry AR
Year: 2023
Journal: Cell Metab
Title: CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression.
Volume: 35
Issue: 11
Pages: 2060-2076.e9
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Publication
17118936 | J:120303
First Author: Cho SY
Year: 2007
Journal: J Biol Chem
Title: Identification of mouse Prp19p as a lipid droplet-associated protein and its possible involvement in the biogenesis of lipid droplets.
Volume: 282
Issue: 4
Pages: 2456-65
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Publication
16118274 | J:101158
First Author: Miyazaki M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development.
Volume: 102
Issue: 35
Pages: 12501-6
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Publication
23919961 | J:208931
First Author: Carobbio S
Year: 2013
Journal: Diabetes
Title: Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.
Volume: 62
Issue: 11
Pages: 3697-708
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Publication
19834103 | J:171803
First Author: Brown JM
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.
Volume: 30
Issue: 1
Pages: 24-30
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Publication
18794388 | J:158044
First Author: Brown JM
Year: 2008
Journal: Circulation
Title: Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.
Volume: 118
Issue: 14
Pages: 1467-75
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Publication
24186867 | J:209003
First Author: Isganaitis E
Year: 2014
Journal: Diabetes
Title: Developmental programming by maternal insulin resistance: hyperinsulinemia, glucose intolerance, and dysregulated lipid metabolism in male offspring of insulin-resistant mice.
Volume: 63
Issue: 2
Pages: 688-700
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Publication
22902781 | J:191771
First Author: Rahman SM
Year: 2012
Journal: J Biol Chem
Title: CCAAT/enhancer-binding protein β (C/EBPβ) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice.
Volume: 287
Issue: 41
Pages: 34349-60
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Publication
25703193 | J:230258
 
First Author: Larsen MC
Year: 2015
Journal: Arch Biochem Biophys
Title: Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis.
Volume: 571
Pages: 21-39
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Publication
27036855 | J:248903
 
First Author: Bushkofsky JR
Year: 2016
Journal: Arch Biochem Biophys
Title: Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα.
Volume: 597
Pages: 30-47
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Publication
21644928 | J:177892
First Author: Li H
Year: 2011
Journal: Biochem J
Title: ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis.
Volume: 438
Issue: 2
Pages: 283-9
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Publication
17341595 | J:120913
First Author: Volle DH
Year: 2007
Journal: Mol Endocrinol
Title: Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility.
Volume: 21
Issue: 5
Pages: 1014-27
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Publication
32198362 | J:286978
First Author: Cabrae R
Year: 2020
Journal: Sci Rep
Title: Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine.
Volume: 10
Issue: 1
Pages: 5186
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Publication
37568579 | J:339082
 
First Author: Zhang R
Year: 2023
Journal: Cancers (Basel)
Title: PTHrP Regulates Fatty Acid Metabolism via Novel lncRNA in Breast Cancer Initiation and Progression Models.
Volume: 15
Issue: 15
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Publication
21300801 | J:170917
First Author: Xu M
Year: 2011
Journal: J Biol Chem
Title: Ncb5or deficiency increases fatty acid catabolism and oxidative stress.
Volume: 286
Issue: 13
Pages: 11141-54
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Publication
25491724 | J:219631
First Author: Wilson GJ
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Volume: 308
Issue: 4
Pages: E283-93
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Publication
19772884 | J:292896
First Author: Arnauld S
Year: 2009
Journal: Biochimie
Title: Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14,643.
Volume: 91
Issue: 11-12
Pages: 1376-86
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Publication
28448568 | J:251674
First Author: Poliakov E
Year: 2017
Journal: PLoS One
Title: Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets β-carotene oxygenase 1, stearoyl-CoA desaturase 1 and dihydroceramide Δ4-desaturase 1.
Volume: 12
Issue: 4
Pages: e0176487
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Publication
31145942 | J:275679
 
First Author: Yamamoto T
Year: 2019
Journal: J Mol Cell Cardiol
Title: Sirt1 counteracts decrease in membrane phospholipid unsaturation and diastolic dysfunction during saturated fatty acid overload.
Volume: 133
Pages: 1-11
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Publication
26134570 | J:224599
First Author: Cui XB
Year: 2015
Journal: J Biol Chem
Title: RGC-32 Deficiency Protects against Hepatic Steatosis by Reducing Lipogenesis.
Volume: 290
Issue: 33
Pages: 20387-95
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Publication
39491648 | J:359500
First Author: Uota A
Year: 2024
Journal: J Biol Chem
Title: ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytes.
Volume: 300
Issue: 12
Pages: 107953
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Publication
28789977 | J:256233
First Author: Cheng J
Year: 2017
Journal: Biochim Biophys Acta
Title: Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization.
Volume: 1863
Issue: 11
Pages: 2783-2790
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Publication
27906582 | J:246405
First Author: Hekmatnejad B
Year: 2017
Journal: Endocrinology
Title: FIAT Deletion Increases Bone Mass But Does Not Prevent High-Fat-Diet-Induced Metabolic Complications.
Volume: 158
Issue: 2
Pages: 264-276
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Publication
26517697 | J:229399
First Author: Masuda M
Year: 2015
Journal: J Clin Invest
Title: Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity.
Volume: 125
Issue: 12
Pages: 4544-58
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Publication
17264204 | J:314559
First Author: Kim JW
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Effect of phosphorylation and S-S bond-induced dimerization on DNA binding and transcriptional activation by C/EBPbeta.
Volume: 104
Issue: 6
Pages: 1800-4
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Publication
8914942 | J:36457
First Author: Paisley EA
Year: 1996
Journal: J Nutr
Title: Temporal-regulation of serum lipids and stearoyl CoA desaturase and lipoprotein lipase mRNA in BALB/cHnn mice.
Volume: 126
Issue: 11
Pages: 2730-7
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Publication
18032385 | J:131339
First Author: Christianson JL
Year: 2008
Journal: J Biol Chem
Title: Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor gamma expression and adipogenesis in cultured 3T3-L1 cells.
Volume: 283
Issue: 5
Pages: 2906-16
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Publication
22546860 | J:188296
First Author: Benhamed F
Year: 2012
Journal: J Clin Invest
Title: The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.
Volume: 122
Issue: 6
Pages: 2176-94
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Publication
28851735 | J:257893
First Author: Lounis MA
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Oleate activates SREBP-1 signaling activity in SCD1-deficient hepatocytes.
Volume: 313
Issue: 6
Pages: E710-E720
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Publication
29524401 | J:273787
First Author: Shao S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Ablation of prolactin receptor increases hepatic triglyceride accumulation.
Volume: 498
Issue: 3
Pages: 693-699
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Publication
32273338 | J:292061
First Author: Iwase M
Year: 2020
Journal: J Biol Chem
Title: Glycerol kinase stimulates uncoupling protein 1 expression by regulating fatty acid metabolism in beige adipocytes.
Volume: 295
Issue: 20
Pages: 7033-7045
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Publication
22874998 | J:300447
 
First Author: Strand DW
Year: 2012
Journal: Cell Death Dis
Title: PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation.
Volume: 3
Pages: e361
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Publication
31920990 | J:312181
 
First Author: Edillor CR
Year: 2019
Journal: Front Endocrinol (Lausanne)
Title: DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains.
Volume: 10
Pages: 882
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Publication
21045115 | J:356626
First Author: Simeone SM
Year: 2011
Journal: Physiol Genomics
Title: Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium.
Volume: 43
Issue: 3
Pages: 148-60
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Publication
33421943 | J:325233
 
First Author: Olga L
Year: 2021
Journal: EBioMedicine
Title: Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity.
Volume: 63
Pages: 103198
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Publication
36439884 | J:331704
First Author: Zhang Y
Year: 2022
Journal: Int J Biol Sci
Title: Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer.
Volume: 18
Issue: 16
Pages: 6114-6128
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Publication
21637860 | J:172712
First Author: Khaidakov M
Year: 2011
Journal: PLoS One
Title: Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer.
Volume: 6
Issue: 5
Pages: e20277
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Publication
23173044 | J:195460
First Author: Okamura T
Year: 2012
Journal: PLoS One
Title: Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.
Volume: 7
Issue: 11
Pages: e49055
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Publication
21609322 | J:175395
First Author: Caton PW
Year: 2011
Journal: Biochem J
Title: PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.
Volume: 437
Issue: 3
Pages: 521-30
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Publication
30935969 | J:291944
 
First Author: Lee DH
Year: 2019
Journal: Metabolism
Title: Chitinase-3-like-1 deficiency attenuates ethanol-induced liver injury by inhibition of sterol regulatory element binding protein 1-dependent triglyceride synthesis.
Volume: 95
Pages: 46-56
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Publication
38272326 | J:345869
 
First Author: Shi W
Year: 2024
Journal: Free Radic Biol Med
Title: Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Volume: 213
Pages: 343-358
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Publication
10493779 | J:59481
 
First Author: Hawes NL
Year: 1999
Journal: Mol Vis
Title: Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes.
Volume: 5
Pages: 22
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Publication
2570068 | J:9973
First Author: Kaestner KH
Year: 1989
Journal: J Biol Chem
Title: Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.
Volume: 264
Issue: 25
Pages: 14755-61
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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