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Search results 501 to 600 out of 878 for Sf1

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Protein
Q99MJ9
Organism: Mus musculus/domesticus
Length: 734  
Fragment?: false
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Protein
P49135
Organism: Mus musculus/domesticus
Length: 783  
Fragment?: false
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Protein
Q60848
Organism: Mus musculus/domesticus
Length: 821  
Fragment?: false
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Protein
Q8VHK9
Organism: Mus musculus/domesticus
Length: 1001  
Fragment?: false
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Protein
Q6PE54
Organism: Mus musculus/domesticus
Length: 779  
Fragment?: false
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Protein
D3Z4R1
Organism: Mus musculus/domesticus
Length: 1434  
Fragment?: false
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Protein
Q80VY9
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
Q04692
Organism: Mus musculus/domesticus
Length: 1021  
Fragment?: false
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Protein
Q14BI7
Organism: Mus musculus/domesticus
Length: 1383  
Fragment?: false
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Protein
Q9Z129
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
Q8BJL0
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
Q3UFL0
Organism: Mus musculus/domesticus
Length: 634  
Fragment?: false
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Protein
Q3UAF1
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
Q3TSJ4
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
Q6NZL1
Organism: Mus musculus/domesticus
Length: 1150  
Fragment?: false
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Protein
Q921Y1
Organism: Mus musculus/domesticus
Length: 1044  
Fragment?: false
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Protein
Q497W9
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
Q6NZR5
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
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Protein
Q3TFE5
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
Q80TX4
Organism: Mus musculus/domesticus
Length: 1018  
Fragment?: true
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Protein
Q5SVX2
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: true
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Protein
Q6IQZ1
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: true
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Protein
Q6PCP0
Organism: Mus musculus/domesticus
Length: 851  
Fragment?: false
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Protein
Q8BQD9
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
A0A0N4SV55
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true
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Protein
Q3U3I5
Organism: Mus musculus/domesticus
Length: 783  
Fragment?: false
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Protein
Q8C2W7
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: false
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Protein
Q8R4Z5
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Protein
Q6A0A1
Organism: Mus musculus/domesticus
Length: 1224  
Fragment?: true
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Protein
Q3TW36
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
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Protein
Q8VDG2
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: true
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Protein
A0A1Y7VKF2
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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Protein
Q3ULC7
Organism: Mus musculus/domesticus
Length: 851  
Fragment?: false
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Protein
Q80TP6
Organism: Mus musculus/domesticus
Length: 1041  
Fragment?: true
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Protein
Q8BRU5
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: false
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Protein
Q6IS54
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Protein
Q5DTX1
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: true
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Protein
Q3TB18
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: false
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Protein
D6RHT5
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein
Q91YU1
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
Q3TUC8
Organism: Mus musculus/domesticus
Length: 586  
Fragment?: true
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Protein
Q3UX55
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: true
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Protein
Q3TE28
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: true
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Protein
Q76MT3
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Protein
F6ZX28
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
A0A0G2JG10
Organism: Mus musculus/domesticus
Length: 608  
Fragment?: false
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Protein
Q8K2L4
Organism: Mus musculus/domesticus
Length: 689  
Fragment?: true
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Protein
G3UX35
Organism: Mus musculus/domesticus
Length: 1267  
Fragment?: true
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Protein
B1ARB9
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: true
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Protein
Q99LR0
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Protein
Q8BTS9
Organism: Mus musculus/domesticus
Length: 594  
Fragment?: true
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Protein
Q3URH5
Organism: Mus musculus/domesticus
Length: 1261  
Fragment?: true
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Protein
Q3TUR4
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: true
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Protein
Q78WR5
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
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Protein
Q3UTV0
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Protein
A0A0G2JES5
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein
Q8CDP6
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
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Protein
J3QM90
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Protein
A0A1Y7VK75
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: true
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Protein
A0A087WP63
Organism: Mus musculus/domesticus
Length: 3095  
Fragment?: true
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Protein
Q922S6
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
A0A589M209
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: false
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Protein
H3BLJ6
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: true
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Protein
Q3UKJ6
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
A0A087WNX7
Organism: Mus musculus/domesticus
Length: 3114  
Fragment?: false
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Protein
D3YWF9
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
E9Q3N0
Organism: Mus musculus/domesticus
Length: 634  
Fragment?: false
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Protein
A0A0N4SVM5
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: true
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Protein
F6Z6F4
Organism: Mus musculus/domesticus
Length: 768  
Fragment?: true
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Protein
O70349
Organism: Mus musculus/domesticus
Length: 1236  
Fragment?: false
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Protein
B2RUM8
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
A0A0G2JGL8
Organism: Mus musculus/domesticus
Length: 1186  
Fragment?: false
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Protein
Q7TPP4
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: true
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Protein
G3X8X0
Organism: Mus musculus/domesticus
Length: 1044  
Fragment?: false
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Protein
A2ACQ1
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
Q9CWZ5
Organism: Mus musculus/domesticus
Length: 832  
Fragment?: false
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Protein
A0A087WQ44
Organism: Mus musculus/domesticus
Length: 3271  
Fragment?: false
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Protein
Q3UUK0
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Protein
Q5BKP5
Organism: Mus musculus/domesticus
Length: 734  
Fragment?: false
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Protein
A0A0N4SVK2
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: true
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Protein
A0A087WNL7
Organism: Mus musculus/domesticus
Length: 3210  
Fragment?: false
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Protein
Q3UDX4
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: true
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Protein
Q66JW6
Organism: Mus musculus/domesticus
Length: 744  
Fragment?: false
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Protein
Q3TSV4
Organism: Mus musculus/domesticus
Length: 916  
Fragment?: true
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Protein
Q9D6S8
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false
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Protein
B2RQS6
Organism: Mus musculus/domesticus
Length: 1000  
Fragment?: false
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Protein
E9QKL0
Organism: Mus musculus/domesticus
Length: 1467  
Fragment?: false
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Protein
Q3UYV7
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: true
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Protein
Q3UZ76
Organism: Mus musculus/domesticus
Length: 995  
Fragment?: true
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Protein
A0A0N4SWC5
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q80X98
Organism: Mus musculus/domesticus
Length: 1228  
Fragment?: false
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Protein
Q8K392
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: false
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Protein
Q8K1G9
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: false
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Publication
2542029 | -
First Author: Lill R
Year: 1989
Journal: EMBO J
Title: SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli.
Volume: 8
Issue: 3
Pages: 961-6
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Publication
12242434 | -
First Author: Hunt JF
Year: 2002
Journal: Science
Title: Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA.
Volume: 297
Issue: 5589
Pages: 2018-26
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Publication
11171974 | -
First Author: Story RM
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii.
Volume: 98
Issue: 4
Pages: 1465-70
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Publication
10404596 | -
First Author: Benz J
Year: 1999
Journal: Structure
Title: Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae--the prototype of the DEAD box protein family.
Volume: 7
Issue: 6
Pages: 671-9
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Publication
8552679 | -
First Author: Jones PG
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Cold shock induces a major ribosomal-associated protein that unwinds double-stranded RNA in Escherichia coli.
Volume: 93
Issue: 1
Pages: 76-80
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Publication
10775271 | -
First Author: Rutz B
Year: 2000
Journal: EMBO J
Title: A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing.
Volume: 19
Issue: 8
Pages: 1873-86
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Protein Domain
IPR014015 | Helicase_SF3_DNA-vir
Type: Domain
Description: Helicases have been classified in 5 superfamilies (SF1-SF5). All of theproteins bind ATP and, consequently, all of them carry the classical Walker A(phosphate-binding loop or P-loop) and Walker B(Mg2+-binding aspartic acid) motifs. Superfamily 3 consists of helicasesencoded mainly by small DNA viruses and some large nucleocytoplasmic DNAviruses [, ]. Small viruses are very dependent on the host-cell machinery toreplicate. SF3 helicase in small viruses is associated with an origin-bindingdomain. By pairing a domain that recognises the ori with a helicase, the viruscan bypass the host-cell-based regulation pathway and initiate its ownreplication. The protein binds to the viral ori leading to origin unwinding.Cellular replication proteins are then recruited to the ori and the viral DNAis replicated.In SF3 helicases the Walker A and Walker B motifs are separated by spacers ofrather uniform, and relatively short, length. In addition to the A and Bmotifs this family is characterised by a third motif (C) which resides betweenthe B motif and the C terminus of the conserved region. This motif consists ofan Asn residue preceded by a run of hydrophobic residues [].Several structures of SF3 helicases have been solved []. Theyall possess the same core alpha/beta fold, consisting of a five-strandedparallel beta sheet flanked on both sides by several alpha helices. Incontrast to SF1 and SF2 helicases, which have RecA-like core folds, the strandconnectivity within the alpha/beta core domain is that of AAA+ proteins [].The SF3 helicase proteins assemble into a hexameric ring.Some proteins known to contain an SF3 helicase domain are listed below:Polyomavirus large T antigen. It initiates DNA unwinding and replicationvia interactions with the viral origin of replication.Papillomavirus E1 protein. An ATP-dependent DNA helicase required forinitiation of viral DNA replication.Parvovirus Rep/NS1 protein, which is also required for the initiation ofviral replication.Poxviridae and other large DNA viruses D5 protein.Bacteriophage DNA primase/helicase protein.Bacterial prophage DNA primase/helicase protein.The entry represents the core alpha/beta fold of the SF3 helicase domain found predominantly in DNA viruses.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom