|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 572 out of 572 for Sgk1

<< First    < Previous  |  Next >    Last >>
0.049s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
UniProt Feature
UniProt Feature
Begin: 346
Description: Phosphothreonine; by SGK1
Type: modified residue
End: 346
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase Sgk1
Type: chain
End: 431
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 659
Description: Phosphoserine; by SGK1
Type: modified residue
End: 659
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 396
Description: Phosphothreonine; by SGK1
Type: modified residue
End: 396
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 477
Description: Phosphoserine; by SGK1
Type: modified residue
End: 477
•
•
•
•
•
Protein
Q9WVC6
Organism: Mus musculus/domesticus
Length: 431  
Fragment?: false
•
•
•
•
•
Protein
Q9WVC6-3
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
•
•
•
•
•
Protein
Q9WVC6-2
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
•
•
•
•
•
Protein
D3Z0E8
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
•
•
•
•
•
Protein
D3YXA3
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
•
•
•
•
•
Protein
D3YV51
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: true
•
•
•
•
•
Protein
E9Q8C1
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: false
•
•
•
•
•
Protein
E9Q1B0
Organism: Mus musculus/domesticus
Length: 417  
Fragment?: false
•
•
•
•
•
Protein
F6RKM6
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
•
•
•
•
•
Publication
30655532 | J:271318
First Author: Ma X
Year: 2019
Journal: Nat Commun
Title: Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation.
Volume: 10
Issue: 1
Pages: 296
•
•
•
•
•
Publication
21224398 | J:182884
First Author: Wallace K
Year: 2011
Journal: J Cell Sci
Title: Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes.
Volume: 124
Issue: Pt 3
Pages: 405-13
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 253
Description: Phosphoserine; by PKB/AKT1 and SGK1
Type: modified residue
End: 253
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 319
Description: Phosphoserine; by CK1 and SGK1
Type: modified residue
End: 319
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 23
Description: Phosphothreonine; by PKB/AKT1 and SGK1
Type: modified residue
End: 23
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 348
Description: Phosphothreonine; by PKB/AKT1 or SGK1
Type: modified residue
End: 348
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 332
Description: Phosphoserine; by PKC/PRKCQ or SGK1
Type: modified residue
End: 332
•
•
•
•
•
Interaction Experiment
Hong F (2008)
Description: mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation.
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 24
Description: Phosphothreonine; by PKB/AKT1 or PKB/AKT2 and SGK1
Type: modified residue
End: 24
•
•
•
•
•
Interaction Experiment
Debonneville C (2001)
Description: Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression.
•
•
•
•
•
Publication
10751222 | -
First Author: Shigaev A
Year: 2000
Journal: Am J Physiol Renal Physiol
Title: Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel.
Volume: 278
Issue: 4
Pages: F613-9
•
•
•
•
•
Publication
8647846 | -
First Author: Maiyar AC
Year: 1996
Journal: J Biol Chem
Title: p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells.
Volume: 271
Issue: 21
Pages: 12414-22
•
•
•
•
•
Publication
12488318 | -
First Author: Leong ML
Year: 2003
Journal: J Biol Chem
Title: Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells.
Volume: 278
Issue: 8
Pages: 5871-82
•
•
•
•
•
Publication
12684516 | -
First Author: Yoo D
Year: 2003
Journal: J Biol Chem
Title: Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A.
Volume: 278
Issue: 25
Pages: 23066-75
•
•
•
•
•
Publication
18570873 | -
First Author: Hong F
Year: 2008
Journal: Mol Cell
Title: mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation.
Volume: 30
Issue: 6
Pages: 701-11
•
•
•
•
•
Allele
Sgk1<em1Smoc> | MGI:7292283
Name: serum/glucocorticoid regulated kinase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 119
Description: Phosphoserine; by CaMK1, CaMK2, CaMK4, PKB/AKT1 or PKB/AKT2, RPS6KA3, RPS6KA4, RPS6KA5 and SGK1
Type: modified residue
End: 119
•
•
•
•
•
Strain
MGI:6355176 | C57BL/6JSmoc-Sgk1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Publication
15461589 | -
First Author: Murray JT
Year: 2004
Journal: Biochem J
Title: Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.
Volume: 384
Issue: Pt 3
Pages: 477-88
•
•
•
•
•
Publication
11742982 | -
First Author: Debonneville C
Year: 2001
Journal: EMBO J
Title: Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression.
Volume: 20
Issue: 24
Pages: 7052-9
•
•
•
•
•
Publication
15774535 | -
First Author: Strutz-Seebohm N
Year: 2005
Journal: J Physiol
Title: Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression.
Volume: 565
Issue: Pt 2
Pages: 391-401
•
•
•
•
•
Publication
20525693 | -
First Author: Heise CJ
Year: 2010
Journal: J Biol Chem
Title: Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.
Volume: 285
Issue: 33
Pages: 25161-7
•
•
•
•
•
Allele
Tg(Myh6-Sgk1*K141M)1Anr | MGI:6456549
Name: transgene insertion 1, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Myh6-Sgk1*S436D)1Anr | MGI:6456553
Name: transgene insertion 1, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
•
•
•
•
•
Publication
35998035 | J:348352
 
First Author: Bapat A
Year: 2022
Journal: JCI Insight
Title: Genetic inhibition of serum glucocorticoid kinase 1 prevents obesity-related atrial fibrillation.
Volume: 7
Issue: 19
•
•
•
•
•
Strain
MGI:6456555 | C57BL/6J-Tg(Myh6-Sgk1*K141M)1Anr/Mmjax
Attribute String: coisogenic, mutant strain, transgenic
•
•
•
•
•
Strain
MGI:6456556 | C57BL/6J-Tg(Myh6-Sgk1*S436D)1Anr/Mmjax
Attribute String: mutant strain, coisogenic, transgenic
•
•
•
•
•
Publication
32690690 | J:295905
First Author: Toyoda Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.
Volume: 117
Issue: 31
Pages: 18175-18177
•
•
•
•
•
Publication
23569215 | J:196677
First Author: Thomanetz V
Year: 2013
Journal: J Cell Biol
Title: Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology.
Volume: 201
Issue: 2
Pages: 293-308
•
•
•
•
•
Publication
17525368 | J:137808
First Author: Santini MP
Year: 2007
Journal: Circ Res
Title: Enhancing repair of the mammalian heart.
Volume: 100
Issue: 12
Pages: 1732-40
•
•
•
•
•
Publication
21063107 | J:178435
First Author: Shumilina E
Year: 2010
Journal: Cell Physiol Biochem
Title: Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells.
Volume: 26
Issue: 4-5
Pages: 699-706
•
•
•
•
•
Publication
18347057 | J:136089
First Author: Bayascas JR
Year: 2008
Journal: Mol Cell Biol
Title: Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Volume: 28
Issue: 10
Pages: 3258-72
•
•
•
•
•
Publication
15240817 | J:94650
First Author: McCormick JA
Year: 2004
Journal: Mol Biol Cell
Title: Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development.
Volume: 15
Issue: 9
Pages: 4278-88
•
•
•
•
•
Publication
31013255 | J:298006
   
First Author: Donadei C
Year: 2019
Journal: JCI Insight
Title: Erythropoietin inhibits SGK1-dependent TH17 induction and TH17-dependent kidney disease.
Volume: 5
•
•
•
•
•
Publication
30487639 | J:341449
First Author: Tertil M
Year: 2018
Journal: Transl Psychiatry
Title: Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation.
Volume: 8
Issue: 1
Pages: 255
•
•
•
•
•
Publication
23620592 | J:199603
First Author: Tao GZ
Year: 2013
Journal: J Biol Chem
Title: Wnt/β-catenin signaling protects mouse liver against oxidative stress-induced apoptosis through the inhibition of forkhead transcription factor FoxO3.
Volume: 288
Issue: 24
Pages: 17214-24
•
•
•
•
•
Publication
24131995 | J:274438
First Author: Singh PK
Year: 2013
Journal: Mol Biol Cell
Title: Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.
Volume: 24
Issue: 24
Pages: 3776-86
•
•
•
•
•
Publication
35975983 | J:344110
   
First Author: Kim JM
Year: 2022
Journal: Elife
Title: Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway.
Volume: 11
•
•
•
•
•
Publication
16825708 | J:116874
First Author: Sandu C
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.
Volume: 291
Issue: 5
Pages: G868-76
•
•
•
•
•
Publication
19720745 | J:153984
First Author: Dibble CC
Year: 2009
Journal: Mol Cell Biol
Title: Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.
Volume: 29
Issue: 21
Pages: 5657-70
•
•
•
•
•
Publication
36511337 | J:334397
 
First Author: Chen B
Year: 2023
Journal: Neurobiol Dis
Title: Activation of Swell1 in microglia suppresses neuroinflammation and reduces brain damage in ischemic stroke.
Volume: 176
Pages: 105936
•
•
•
•
•
Publication
20237237 | J:159986
First Author: Ke Y
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: COMMD1 downregulates the epithelial sodium channel through Nedd4-2.
Volume: 298
Issue: 6
Pages: F1445-56
•
•
•
•
•
Publication
23339081 | J:193388
First Author: Slezak M
Year: 2013
Journal: Glia
Title: Astrocytes are a neural target of morphine action via glucocorticoid receptor-dependent signaling.
Volume: 61
Issue: 4
Pages: 623-35
•
•
•
•
•
Publication
20410134 | J:200370
First Author: Liang X
Year: 2010
Journal: Mol Biol Cell
Title: AS160 modulates aldosterone-stimulated epithelial sodium channel forward trafficking.
Volume: 21
Issue: 12
Pages: 2024-33
•
•
•
•
•
Publication
25265063 | J:219303
First Author: He J
Year: 2015
Journal: Exp Cell Res
Title: Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: role of mTORC2/SGK1 pathway.
Volume: 331
Issue: 1
Pages: 164-75
•
•
•
•
•
Publication
25805816 | J:220829
First Author: Lin DH
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).
Volume: 112
Issue: 14
Pages: 4495-500
•
•
•
•
•
Publication
27298316 | J:235793
First Author: Savas Ü
Year: 2016
Journal: J Biol Chem
Title: 20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR.
Volume: 291
Issue: 32
Pages: 16904-19
•
•
•
•
•
Publication
31107524 | J:279119
First Author: Seow BKL
Year: 2019
Journal: Endocrinology
Title: Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts.
Volume: 160
Issue: 8
Pages: 1868-1884
•
•
•
•
•
Publication
32951297 | J:296938
First Author: Del Llano E
Year: 2020
Journal: Aging Cell
Title: Age-related differences in the translational landscape of mammalian oocytes.
Volume: 19
Issue: 10
Pages: e13231
•
•
•
•
•
Publication
28106162 | J:323752
 
First Author: Chen WY
Year: 2017
Journal: Sci Rep
Title: Heterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation.
Volume: 7
Pages: 41159
•
•
•
•
•
Publication
10548550 | J:58667
 
First Author: Kobayashi T
Year: 1999
Journal: Biochem J
Title: Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.
Volume: 344 Pt 1
Pages: 189-97
•
•
•
•
•
Publication
32223380 | J:313287
First Author: Han X
Year: 2020
Journal: Hypertension
Title: Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells.
Volume: 75
Issue: 5
Pages: 1233-1241
•
•
•
•
•
Publication
18987114 | J:143764
First Author: Boini KM
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Proteinuria in mice expressing PKB/SGK-resistant GSK3.
Volume: 296
Issue: 1
Pages: F153-9
•
•
•
•
•
Publication
20926631 | J:166936
First Author: Pao AC
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney.
Volume: 299
Issue: 6
Pages: F1496-506
•
•
•
•
•
Publication
38047299 | J:345571
First Author: Farrell CE
Year: 2024
Journal: Am J Physiol Cell Physiol
Title: MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport.
Volume: 326
Issue: 1
Pages: C282-C293
•
•
•
•
•
Publication
19144862 | J:356533
First Author: Kim SH
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium.
Volume: 296
Issue: 3
Pages: C544-57
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•
Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom