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Search results 501 to 600 out of 604 for Sim2

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Specimen Label: 9A
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Specimen Label: 9B
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3507791
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3507791
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539287
Age: embryonic day 15.5
Image: GUDMAP:5580
Specimen Label: GUDMAP:5580
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437406
Assay Type: RNA in situ
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6437448
Age: embryonic day 12.5
Note: Expression enhanced in ventral muscle masses of forelimbs and hindlimbs.
Specimen Label: E12.5 not shown
Detected: true
Specimen Num: 12
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•
•
GXD Expression
GXD Expression
Probe: MGI:6695786
Assay Type: RNA in situ
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6695824
Age: embryonic day 13.5
Image: 3D Fore +/+
Note: Expression is ventral-distal domain.
Specimen Label: 3D Fore +/+
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
Probe: MGI:6695786
Assay Type: RNA in situ
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6695824
Age: embryonic day 13.5
Image: 3D Fore -/-
Note: Expression is in a ventral-distal and dorsal-distal domain.
Specimen Label: 3D Fore -/-
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3507791
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3507791
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7709697
Assay Type: RNA in situ
Annotation Date: 2024-08-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:7709698
Age: embryonic day 13.5
Specimen Label: Table 1 E13.5
Detected: false
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437406
Assay Type: RNA in situ
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6437448
Age: embryonic day 14.5
Note: Expression only around digit cartilage.
Specimen Label: E14.5 not shown
Detected: true
Specimen Num: 13
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539287
Age: embryonic day 15.5
Image: GUDMAP:5580
Specimen Label: GUDMAP:5580
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Image: MY220; Specimen C1286
Specimen Label: MY220; Specimen C1286
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Specimen Label: 9A
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Specimen Label: 9B
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6479667
Assay Type: RNA in situ
Annotation Date: 2020-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6479668
Age: embryonic day 12.5
Note: Expression is at the basio-occipital anlage.
Specimen Label: 1c
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6479667
Assay Type: RNA in situ
Annotation Date: 2020-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6479668
Age: embryonic day 12.5
Note: Expression is at the basio-occipital anlage.
Specimen Label: 1d
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506266
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2860123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539287
Age: embryonic day 15.5
Image: GUDMAP:12244
Specimen Label: GUDMAP:12244
Specimen Num: 2
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7709697
Assay Type: RNA in situ
Annotation Date: 2024-08-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7709698
Age: postnatal adult
Specimen Label: Table 1 adult
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Image: MY220; Specimen C1286
Note: Expression was weak in the skull (base and vault).
Specimen Label: MY220; Specimen C1286
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5309663
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423015
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MY220; Specimen C1286
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Note: Expressed in the central tubules.
Specimen Label: 9A
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Note: Expressed in the central tubules.
Specimen Label: 9B
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7709697
Assay Type: RNA in situ
Annotation Date: 2024-08-16
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7709698
Age: postnatal adult
Specimen Label: Table 1 adult
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3677820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6471822
Age: embryonic day 12.5
Specimen Label: not shown
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3677824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Note: Expressed in the lateral mammillary nuclei.
Specimen Label: not shown
Detected: true
Specimen Num: 11
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6471776
Assay Type: RNA in situ
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3740924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471822
Age: embryonic day 16.5
Specimen Label: not shown
Detected: true
Specimen Num: 11
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Publication
11336779 | J:69888
First Author: Galdzicki Z
Year: 2001
Journal: Brain Res Brain Res Rev
Title: On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models.
Volume: 35
Issue: 2
Pages: 115-45
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Publication
10837894 | J:62599
First Author: Vialard F
Year: 2000
Journal: Brain Res Dev Brain Res
Title: Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study.
Volume: 121
Issue: 1
Pages: 73-8
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Publication
9199929 | J:41132
First Author: Michaud J
Year: 1997
Journal: Genome Res
Title: Single-minded--two genes, three chromosomes.
Volume: 7
Issue: 6
Pages: 569-71
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Publication
8661115 | J:33928
First Author: Moffett P
Year: 1996
Journal: Genomics
Title: Characterization of msim, a murine homologue of the Drosophila sim transcription factor.
Volume: 35
Issue: 1
Pages: 144-55
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Publication
17110583 | J:134028
First Author: Levesque BM
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: NPAS1 regulates branching morphogenesis in embryonic lung.
Volume: 36
Issue: 4
Pages: 427-34
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Publication
8561800 | J:30907
First Author: Ema M
Year: 1996
Journal: Biochem Biophys Res Commun
Title: cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.
Volume: 218
Issue: 2
Pages: 588-94
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Publication
8906497 | J:36064
First Author: Mastick GS
Year: 1996
Journal: J Comp Neurol
Title: Early deletion of neuromeres in Wnt-1-/- mutant mice: evaluation by morphological and molecular markers.
Volume: 374
Issue: 2
Pages: 246-58
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Publication
18160708 | J:132635
First Author: Laffin B
Year: 2008
Journal: Mol Cell Biol
Title: Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2.
Volume: 28
Issue: 6
Pages: 1936-46
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Publication
11025203 | J:65378
First Author: Sadek CM
Year: 2000
Journal: Mech Dev
Title: Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.
Volume: 97
Issue: 1-2
Pages: 13-26
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Publication
8927054 | J:35345
First Author: Ema M
Year: 1996
Journal: Mol Cell Biol
Title: Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.
Volume: 16
Issue: 10
Pages: 5865-75
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Publication
9704006 | J:49044
First Author: Takahata S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock.
Volume: 248
Issue: 3
Pages: 789-94
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Publication
9750193 | J:50129
First Author: Cabin DE
Year: 1998
Journal: Genome Res
Title: Physical and comparative mapping of distal mouse chromosome 16. 5 p5.
Volume: 8
Issue: 9
Pages: 940-50
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Publication
9232602 | J:41401
First Author: Grindley JC
Year: 1997
Journal: Mech Dev
Title: Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.
Volume: 64
Issue: 1-2
Pages: 111-26
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Publication
16860307 | J:119269
First Author: Caqueret A
Year: 2006
Journal: Dev Biol
Title: Laminar organization of the early developing anterior hypothalamus.
Volume: 298
Issue: 1
Pages: 95-106
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Publication
38280850 | J:344941
First Author: Yan F
Year: 2024
Journal: Nat Commun
Title: Single-cell multiomics decodes regulatory programs for mouse secondary palate development.
Volume: 15
Issue: 1
Pages: 821
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Publication
31340933 | J:293200
 
First Author: Vanyai HK
Year: 2019
Journal: Development
Title: MOZ directs the distal-less homeobox gene expression program during craniofacial development.
Volume: 146
Issue: 14
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Publication
22972697 | J:187966
First Author: Jeong J
Year: 2012
Journal: Dev Dyn
Title: Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate.
Volume: 241
Issue: 11
Pages: 1757-69
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Publication
28011632 | J:239547
First Author: Sivakamasundari V
Year: 2017
Journal: Biol Open
Title: A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.
Volume: 6
Issue: 2
Pages: 187-199
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Publication
32040930 | J:287549
First Author: Xu J
Year: 2020
Journal: J Dent Res
Title: Genome-wide Identification of Foxf2 Target Genes in Palate Development.
Volume: 99
Issue: 4
Pages: 463-471
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Publication
20589901 | J:161785
First Author: Gu WX
Year: 2010
Journal: Dev Dyn
Title: Identification of genes controlled by LMX1B in E13.5 mouse limbs.
Volume: 239
Issue: 8
Pages: 2246-55
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Publication
27120339 | J:248734
First Author: Bolt CC
Year: 2016
Journal: PLoS One
Title: Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.
Volume: 11
Issue: 4
Pages: e0154413
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Publication
11374901 | J:69920
First Author: Pletcher MT
Year: 2001
Journal: Genomics
Title: Use of comparative physical and sequence mapping to annotate mouse chromosome 16 and human chromosome 21.
Volume: 74
Issue: 1
Pages: 45-54
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Publication
9244437 | J:42076
First Author: Reeves RH
Year: 1997
Journal: Genomics
Title: High-resolution recombinational map of mouse chromosome 16.
Volume: 43
Issue: 2
Pages: 202-8
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Publication
35700056 | J:326661
 
First Author: Xu P
Year: 2022
Journal: J Clin Invest
Title: Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.
Volume: 132
Issue: 14
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Publication
24705356 | J:213620
First Author: Kong P
Year: 2014
Journal: Hum Mol Genet
Title: Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Volume: 23
Issue: 16
Pages: 4215-31
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Publication
19000842 | J:142800
First Author: Brunskill EW
Year: 2008
Journal: Dev Cell
Title: Atlas of gene expression in the developing kidney at microanatomic resolution.
Volume: 15
Issue: 5
Pages: 781-91
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Publication
12466855 | J:80501
First Author: Gitton Y
Year: 2002
Journal: Nature
Title: A gene expression map of human chromosome 21 orthologues in the mouse.
Volume: 420
Issue: 6915
Pages: 586-90
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Publication
12466854 | J:80502
First Author: Reymond A
Year: 2002
Journal: Nature
Title: Human chromosome 21 gene expression atlas in the mouse.
Volume: 420
Issue: 6915
Pages: 582-6
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Publication
18557763 | J:140152
First Author: Stevens JD
Year: 2008
Journal: Differentiation
Title: Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.
Volume: 76
Issue: 9
Pages: 1006-22
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Publication
22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
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First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Sim2<tm1Shmb> | MGI:2384488
Name: single-minded family bHLH transcription factor 2; targeted mutation 1, M J Shamblott
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
9199934 | J:41129
First Author: Chrast R
Year: 1997
Journal: Genome Res
Title: Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.
Volume: 7
Issue: 6
Pages: 615-24
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Protein
Q56DJ6
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
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Publication
7756254 | -
First Author: Borgstahl GE
Year: 1995
Journal: Biochemistry
Title: 1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.
Volume: 34
Issue: 19
Pages: 6278-87
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Publication
11091086 | -
First Author: Coumailleau P
Year: 2000
Journal: Mech Dev
Title: Characterization and developmental expression of xSim, a Xenopus bHLH/PAS gene related to the Drosophila neurogenic master gene single-minded.
Volume: 99
Issue: 1-2
Pages: 163-6
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Protein Domain
IPR010578 | SIM_C
Type: Domain
Description: In Drosophila, single-minded (sim) is a transcription factor that acts as the master regulator of neurogenesis. Two mammalian homologues of Sim which have been identified, Sim1 and Sim2, are novel heterodimerisation partners for ARNT in vitro, and may function both as positive and negative transcriptional regulators in vivo, during embryogenesis and in the adult organism []. SIM2 is thought to contribute to some specific Down syndrome phenotypes []. There is a high level of homology among mammalian and Drosophila sim proteins in their amino-terminal half where the conserved bHLH, PAS () and PAC motifs are present (). The PAC region occurs C-terminal to the PAS domains and are proposed to contribute to the PAS domain fold [, , ]. In contrast, the carboxy-terminal parts are only conserved in vertebrates []. The Sim1 C terminus contains a Ser-rich region, whereas the Sim2 C terminus both contain Ser/Thr-rich regions, Pro/Ser-rich regions, Pro/Ala-rich regions, and positively charged regions. Sim2s, a splice variant of Sim2, still contains the Ser/Thr- and Pro/Ser-rich regions shown to harbor repressive activities, but is missing the Pro/Ala-rich repressor region [, , ].
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Publication
20176810 | J:161708
First Author: Yang SH
Year: 2010
Journal: Mol Cell Biol
Title: The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif.
Volume: 30
Issue: 9
Pages: 2193-205
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Publication
9382818 | -
First Author: Ponting CP
Year: 1997
Journal: Curr Biol
Title: PAS: a multifunctional domain family comes to light.
Volume: 7
Issue: 11
Pages: R674-7
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Publication
33459151 | J:332168
First Author: Oe M
Year: 2021
Journal: Physiol Genomics
Title: Difference in potential DNA methylation impact on gene expression between fast- and slow-type myofibers.
Volume: 53
Issue: 2
Pages: 69-83
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Publication
23103828 | J:192164
First Author: Spellman C
Year: 2013
Journal: Gene
Title: Expression of trisomic proteins in Down syndrome model systems.
Volume: 512
Issue: 2
Pages: 219-25
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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