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Search results 501 to 600 out of 651 for Snap25

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Type Details Score
Publication
First Author: Gould TW
Year: 2019
Journal: PLoS Genet
Title: Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.
Volume: 15
Issue: 3
Pages: e1007948
Publication
First Author: Parras A
Year: 2018
Journal: Nature
Title: Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Volume: 560
Issue: 7719
Pages: 441-446
Publication
First Author: Vitureira N
Year: 2010
Journal: PLoS One
Title: Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation.
Volume: 5
Issue: 8
Pages: e12003
Publication
First Author: Bouwman J
Year: 2004
Journal: Neuroscience
Title: Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.
Volume: 126
Issue: 1
Pages: 115-26
Publication
First Author: Kim SY
Year: 2017
Journal: J Biol Chem
Title: Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes.
Volume: 292
Issue: 9
Pages: 3841-3853
Publication
First Author: Chalazonitis A
Year: 2011
Journal: J Neurosci
Title: Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.
Volume: 31
Issue: 39
Pages: 13746-57
Publication
First Author: Zhao Q
Year: 2022
Journal: Nature
Title: A multidimensional coding architecture of the vagal interoceptive system.
Volume: 603
Issue: 7903
Pages: 878-884
Publication
First Author: Schappe MS
Year: 2024
Journal: Nature
Title: A vagal reflex evoked by airway closure.
Volume: 627
Issue: 8005
Pages: 830-838
Publication
First Author: Medrihan L
Year: 2009
Journal: J Physiol
Title: Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.
Volume: 587
Issue: Pt 21
Pages: 5095-106
Publication
First Author: Hall EA
Year: 2017
Journal: Am J Hum Genet
Title: PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
Volume: 100
Issue: 5
Pages: 706-724
Publication
First Author: Rowan S
Year: 2004
Journal: Development
Title: Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10.
Volume: 131
Issue: 20
Pages: 5139-52
Publication
First Author: Schoch S
Year: 2006
Journal: EMBO J
Title: Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
Volume: 25
Issue: 24
Pages: 5852-63
Publication      
First Author: Zhang M
Year: 2017
Journal: Genes Dev
Title: Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
Publication
First Author: Niquille M
Year: 2009
Journal: PLoS Biol
Title: Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C.
Volume: 7
Issue: 10
Pages: e1000230
Publication
First Author: Gehman LT
Year: 2012
Journal: Genes Dev
Title: The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.
Volume: 26
Issue: 5
Pages: 445-60
Publication
First Author: Goulley J
Year: 2007
Journal: Cell Metab
Title: BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion.
Volume: 5
Issue: 3
Pages: 207-19
Publication  
First Author: Kunii M
Year: 2021
Journal: J Cell Biol
Title: SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity.
Volume: 220
Issue: 1
Publication
First Author: Cattaneo P
Year: 2022
Journal: Nat Commun
Title: DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.
Volume: 13
Issue: 1
Pages: 7444
Publication
First Author: Kelkar N
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).
Volume: 100
Issue: 17
Pages: 9843-8
Publication  
First Author: Garaffo G
Year: 2013
Journal: Front Endocrinol (Lausanne)
Title: Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.
Volume: 4
Pages: 203
Publication
First Author: Toonen RF
Year: 2005
Journal: J Neurochem
Title: Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.
Volume: 93
Issue: 6
Pages: 1393-400
Publication
First Author: Olsen O
Year: 2005
Journal: J Cell Biol
Title: Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.
Volume: 170
Issue: 7
Pages: 1127-34
Publication
First Author: Munz M
Year: 2023
Journal: Cell
Title: Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex.
Volume: 186
Issue: 9
Pages: 1930-1949.e31
Publication
First Author: Zuberi AR
Year: 1996
Journal: Genomics
Title: A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.
Volume: 33
Issue: 1
Pages: 75-84
Publication
First Author: Mao Y
Year: 2024
Journal: J Neuroinflammation
Title: Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Volume: 21
Issue: 1
Pages: 249
Publication
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
Publication
First Author: Licatalosi DD
Year: 2012
Journal: Genes Dev
Title: Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.
Volume: 26
Issue: 14
Pages: 1626-42
Publication
First Author: Lyu MS
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the human and mouse phospholipase C genes.
Volume: 7
Issue: 7
Pages: 501-4
Publication
First Author: Ehringer MA
Year: 2001
Journal: Mamm Genome
Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.
Volume: 12
Issue: 8
Pages: 657-63
Publication
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
Publication  
First Author: Nechiporuk T
Year: 2016
Journal: Elife
Title: The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Volume: 5
Pages: e09584
Publication
First Author: Zhang Q
Year: 2018
Journal: Cell Death Dis
Title: Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.
Volume: 9
Issue: 2
Pages: 247
Publication
First Author: Osipovich AB
Year: 2014
Journal: Development
Title: Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Volume: 141
Issue: 15
Pages: 2939-49
Publication
First Author: Kozak CA
Year: 1999
Journal: Mamm Genome
Title: Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.
Volume: 10
Issue: 9
Pages: 853-7
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication      
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
Publication      
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
Publication
First Author: Nakano Y
Year: 2019
Journal: Cell Rep
Title: Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Volume: 27
Issue: 3
Pages: 860-871.e8
Publication
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Won KH
Year: 2020
Journal: Mol Cells
Title: Functions of the Plant Qbc SNARE SNAP25 in Cytokinesis and Biotic and Abiotic Stress Responses.
Volume: 43
Issue: 4
Pages: 313-322
Allele
Name: transgene insertion 40, Michael C Wilson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 47DSJD, Joseph D Dougherty
Allele Type: Transgenic
Attribute String: Recombinase
DO Term
Publication
First Author: Sapkota D
Year: 2020
Journal: Neural Dev
Title: An inducible Cre mouse line to sparsely target nervous system cells, including Remak Schwann cells.
Volume: 15
Issue: 1
Pages: 2
Allele
Name: transgene insertion 8, Xiao-Jiang Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Xu Q
Year: 2013
Journal: J Cell Biol
Title: Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.
Volume: 202
Issue: 7
Pages: 1123-38
Strain
Attribute String: mutant strain, transgenic
Allele
Name: synaptosomal-associated protein 25; targeted mutation 1.1, Saaid Safieddine
Allele Type: Targeted
Attribute String: Conditional ready
Genotype
Symbol: Cm/+ Tg(Snap25)40Micw/Tg(Snap25)40Micw
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cm/+ Tg(Snap25)40Micw/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-SNAP25/HTT*150Q)8Xjl/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
Allele
Name: transgene insertion 1861, Nathaniel Heintz
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 1989, Nathaniel Heintz
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 1849, Nathaniel Heintz
Allele Type: Transgenic
Attribute String: Reporter
Publication
First Author: El Kasmi F
Year: 2013
Journal: Mol Biol Cell
Title: SNARE complexes of different composition jointly mediate membrane fusion in Arabidopsis cytokinesis.
Volume: 24
Issue: 10
Pages: 1593-601
Publication
First Author: Zheng H
Year: 2002
Journal: Plant Physiol
Title: NPSN11 is a cell plate-associated SNARE protein that interacts with the syntaxin KNOLLE.
Volume: 129
Issue: 2
Pages: 530-9
Publication
First Author: Sanderfoot AA
Year: 2000
Journal: Plant Physiol
Title: The Arabidopsis genome. An abundance of soluble N-ethylmaleimide-sensitive factor adaptor protein receptors.
Volume: 124
Issue: 4
Pages: 1558-69
Protein Domain
Type: Domain
Description: Soluble N-ethylmaleimide attachment protein receptor (SNARE) proteins are a family of membrane-associated proteins characterised by an α-helical coiled-coil domain called the SNARE motif []. These proteins are classified as v-SNAREs and t-SNAREs based on their localisation on vesicle or target membrane; another classification scheme defines R-SNAREs and Q-SNAREs, as based on the conserved arginine or glutamine residue in the centre of the SNARE motif []. SNAREs are localised to distinct membrane compartments of the secretory and endocytic trafficking pathways, and contribute to the specificity of intracellular membrane fusion processes.The t-SNARE domain consists of a 4-helical bundle with a coiled-coil twist. The SNARE motif contributes to the fusion of two membranes. SNARE motifs fall into four classes: homologues of syntaxin 1a (t-SNARE), VAMP-2 (v-SNARE), and the N- and C-terminal SNARE motifs of SNAP-25.This entry represents the N-terminal SNARE motif found in plant SNAP25 homologues, SNAP29, SNAP30 and SNAP33 [, , ], and in the novel plant SNAREs (NPSNs) 11, 12 and 13 from Arabidopsis thaliana [, ]. SNAP33 and NPS11 play a key role in cytokinesis [, ]. SNAP33, the most studied SNAP25 homologue in Arabidopsis, is also involved in triggering innate immune responses. SNAP29 and SNAP30 have not been well-characterised yet [].
Strain
Attribute String: transgenic, coisogenic, mutant strain
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: synaptosomal-associated protein 25; targeted mutation 1.1, Hongkui Zeng
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: synaptosomal-associated protein 25; targeted mutation 2.1, Hongkui Zeng
Allele Type: Targeted
Attribute String: Recombinase
Publication
First Author: Suh YH
Year: 2011
Journal: PLoS One
Title: Deletion of SNAP-23 results in pre-implantation embryonic lethality in mice.
Volume: 6
Issue: 3
Pages: e18444
Publication
First Author: Chheda MG
Year: 2001
Journal: Nat Cell Biol
Title: Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex.
Volume: 3
Issue: 4
Pages: 331-8
Publication
First Author: Evans GJ
Year: 2003
Journal: Biochem Soc Trans
Title: Regulation of the exocytotic machinery by cAMP-dependent protein kinase: implications for presynaptic plasticity.
Volume: 31
Issue: Pt 4
Pages: 824-7
Publication
First Author: Ginter-Matuszewska B
Year: 2009
Journal: Mol Hum Reprod
Title: The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.
Volume: 15
Issue: 3
Pages: 173-9
Protein Domain
Type: Family
Description: Snapin is a component of the biogenesis of lysosomal organelles complex-1 (BLOC-1), a complex required for the normal biogenesis of lysosome-related organelles, such as melanosomes and platelet dense granules [], and endosomal cargo sorting [].Snapin binds to SNAP-25, part of the SNARE complex that mediates the synaptic vesicle docking and fusion []. Snapin may modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25 []. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis [, ]. It may also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells [].
Strain
Attribute String: mutant strain, targeted mutation, congenic
Strain
Attribute String: targeted mutation, mutant stock
Genotype
Symbol: Snap25/Snap25<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Snap25/Snap25<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr
Zygosity: ht
Has Mutant Allele: true
Publication  
First Author: Ciani L
Year: 2015
Journal: Nat Commun
Title: Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1.
Volume: 6
Pages: 8302
Publication
First Author: Emperador-Melero J
Year: 2018
Journal: Nat Commun
Title: Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi.
Volume: 9
Issue: 1
Pages: 3421