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Search results 501 to 567 out of 567 for Sox3

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Type Details Score
DO Term
DOID:0111779 | X-linked panhypopituitarism
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Allele
Sox3<em1Smoc> | MGI:7292542
Name: SRY (sex determining region Y)-box 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0111762 | 46,XX sex reversal 3
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GXD Expression
GXD Expression
Probe: MGI:6379679
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436571
Age: postnatal adult
Image: 2I
Note: Expression not co-localizing with Sox3 within any cells of dentate gyrus.
Specimen Label: 2I
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6379679
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436571
Age: postnatal adult
Image: 2J
Note: Expression not co-localizing with Sox3 within any cells of dentate gyrus.
Specimen Label: 2J
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5693887
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6436568
Age: embryonic day 14.5
Image: 1E
Note: Expression not co-localizing with that of Sox3 within dorsal telencephalic vesicles.
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6436319
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3583128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436569
Age: postnatal adult
Image: 2F/G
Note: Co-localization of expression with Sox3 in radially projecting cells of subgranular layer of dentate gyrus.
Specimen Label: 2F/G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2154446
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3583128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436566
Age: postnatal adult
Image: 2C/D
Note: Co-localization of expression with Sox3 in subgranular layer of dentate gyrus.
Specimen Label: 2C/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6379679
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436571
Age: postnatal adult
Image: 3E
Note: Expression not co-localizing with Sox3 in any cells of lateral ventricles.
Specimen Label: 3E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6436322
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436570
Age: postnatal adult
Image: 3D
Note: Co-localization of expression with Sox3 within subventricular zone of lateral ventricles.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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Publication
15800844 | -
First Author: Woods KS
Year: 2005
Journal: Am J Hum Genet
Title: Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism.
Volume: 76
Issue: 5
Pages: 833-49
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Publication
12428212 | -
First Author: Laumonnier F
Year: 2002
Journal: Am J Hum Genet
Title: Transcription factor SOX3 is involved in X-linked mental retardation with growth hormone deficiency.
Volume: 71
Issue: 6
Pages: 1450-5
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Regulatory Region
MGI:4421017 | Rr4
Type: enhancer
Organism: mouse, laboratory
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Publication
7748786 | -
First Author: Uwanogho D
Year: 1995
Journal: Mech Dev
Title: Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development.
Volume: 49
Issue: 1-2
Pages: 23-36
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Publication
12748963 | -
First Author: Brunelli S
Year: 2003
Journal: Genesis
Title: Expression of Sox3 throughout the developing central nervous system is dependent on the combined action of discrete, evolutionarily conserved regulatory elements.
Volume: 36
Issue: 1
Pages: 12-24
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Allele
Tg(SrySox3)35Ei | MGI:3623264
Name: transgene insertion 35, Eva Eicher
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SrySox3)32Ei | MGI:3623265
Name: transgene insertion 32, Eva Eicher
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SrySox3)36Ei | MGI:3623266
Name: transgene insertion 36, Eva Eicher
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SrySox3)78Ei | MGI:3623267
Name: transgene insertion 78, Eva Eicher
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SrySox3)77Ei | MGI:3623275
Name: transgene insertion 77, Eva Eicher
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Sox3-EGFP)MT59Gsat | MGI:5051802
Name: transgene insertion MT59, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Sox3-EGFP)NrPqt | MGI:5428449
Name: transgene insertion Nr, Paul Q Thomas
Allele Type: Transgenic
Attribute String: Reporter
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HT Experiment
GSE96805 | SOXB1 genetic regulation in the developing testes
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Allele
Sox3<tm1Rlb> | MGI:3036671
Name: SRY (sex determining region Y)-box 3; targeted mutation 1, Robin Lovell-Badge
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5496564 | STOCK Tg(Sox3-EGFP)MT59Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Allele
Tg(Sox3-GFP,Tyr)HolNpln | MGI:5774447
Name: transgene insertion Hol, Nicolas Pilon
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Sox3-cre/ERT2)#Syos | MGI:7461181
Name: transgene insertion, Shosei Yoshida
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Tg(Sox3)1Pqt/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Sox3-EGFP)NrPqt/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Publication
26571399 | J:229828
First Author: Soret R
Year: 2015
Journal: J Clin Invest
Title: A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.
Volume: 125
Issue: 12
Pages: 4483-96
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Publication
34884944 | J:316193
 
First Author: Soret R
Year: 2021
Journal: Int J Mol Sci
Title: Genetic Background Influences Severity of Colonic Aganglionosis and Response to GDNF Enemas in the Holstein Mouse Model of Hirschsprung Disease.
Volume: 22
Issue: 23
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Allele
Hprt1<tm355(Ple286-icre/ERT2)Ems> | MGI:5568226
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 355, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Sox3/Sox3<+>
Background: involves: 129S7/SvEvBrd * MF1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox3/?
Background: involves: 129S7/SvEvBrd * MF1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox3/Sox3
Background: involves: 129S7/SvEvBrd * MF1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4<+> Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Sox3-GFP,Tyr)HolNpln/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:5570187 | B6.Cg-Hprt1<tm355(Ple286-icre/ERT2)Ems>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:5568360 | B6.Cg-Hprt1<tm355(Ple286-icre/ERT2)Ems>/Mmjax
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Tg(Sox3)1Pqt/? Tg(Sox3-EGFP)NrPqt/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: B6.Cg-Hprt1
Zygosity: ot
Has Mutant Allele: true
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HT Experiment
GSE112935 | RNA-seq analysis dataset: FACS-sorted Ptf1a-lineage cells from E14.5 hypothalamus of Ptf1a hetero and homozygous mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE70713 | Single-cell analysis reveals lineage segregation and pluripotency state transition in early post-implantation mouse embryos
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
35698877 | J:361544
 
First Author: Lu C
Year: 2022
Journal: Development
Title: Casein kinase 1α regulates murine spermatogenesis via p53-Sox3 signaling.
Volume: 149
Issue: 13
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Publication
15110721 | J:90645
First Author: Kan L
Year: 2004
Journal: Dev Biol
Title: Sox1 acts through multiple independent pathways to promote neurogenesis.
Volume: 269
Issue: 2
Pages: 580-94
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Publication
15533723 | J:93959
First Author: Andrew Nesbit M
Year: 2004
Journal: Genomics
Title: X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase.
Volume: 84
Issue: 6
Pages: 1060-70
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Publication
25786024 | J:224231
First Author: Bergeron KF
Year: 2015
Journal: PLoS Genet
Title: Male-biased aganglionic megacolon in the TashT mouse line due to perturbation of silencer elements in a large gene desert of chromosome 10.
Volume: 11
Issue: 3
Pages: e1005093
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Publication
30679567 | J:275001
First Author: Touré AM
Year: 2019
Journal: Sci Rep
Title: Gut microbiota-mediated Gene-Environment interaction in the TashT mouse model of Hirschsprung disease.
Volume: 9
Issue: 1
Pages: 492
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Genotype
Genotype
Symbol: Sox2/Sox2 Sox3/Sox3
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * MF1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-cat,-EGFP)39Miya/? Tg(Sox3-cre/ERT2)#Syos/?
Background: involves: C57BL/6 * DBA/2NJcl
Zygosity: cn
Has Mutant Allele: true
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Publication
22056784 | J:179399
First Author: Suzuki H
Year: 2012
Journal: Dev Biol
Title: SOHLH1 and SOHLH2 coordinate spermatogonial differentiation.
Volume: 361
Issue: 2
Pages: 301-12
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Publication
10588878 | J:58862
First Author: Zhu L
Year: 1999
Journal: Dev Biol
Title: Goosecoid regulates the neural inducing strength of the mouse node.
Volume: 216
Issue: 1
Pages: 276-81
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Publication
27350561 | J:236413
First Author: Mona B
Year: 2016
Journal: Dev Biol
Title: Regulating the dorsal neural tube expression of Ptf1a through a distal 3' enhancer.
Volume: 418
Issue: 1
Pages: 216-225
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Publication
11069290 | J:65912
First Author: Pask A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The human sex-reversing ATRX gene has a homologue on the marsupial Y chromosome, ATRY: implications for the evolution of mammalian sex determination.
Volume: 97
Issue: 24
Pages: 13198-202
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Publication
8127908 | J:17104
First Author: Foster JW
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: An SRY-related sequence on the marsupial X chromosome: implications for the evolution of the mammalian testis-determining gene.
Volume: 91
Issue: 5
Pages: 1927-31
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Publication
21787741 | J:176311
First Author: Kobayashi Y
Year: 2011
Journal: Am J Pathol
Title: Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV12.
Volume: 179
Issue: 3
Pages: 1471-82
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Publication
21856426 | J:189262
First Author: Slawny NA
Year: 2011
Journal: Mol Cell Neurosci
Title: Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells.
Volume: 48
Issue: 3
Pages: 205-16
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Publication
25404322 | J:222752
First Author: Keverne EB
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Genomic imprinting, action, and interaction of maternal and fetal genomes.
Volume: 112
Issue: 22
Pages: 6834-40
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Publication
28298438 | J:243676
First Author: Wen J
Year: 2017
Journal: J Biol Chem
Title: Single-cell analysis reveals lineage segregation in early post-implantation mouse embryos.
Volume: 292
Issue: 23
Pages: 9840-9854
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Publication
9609835 | J:49378
First Author: Kamachi Y
Year: 1998
Journal: Development
Title: Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction.
Volume: 125
Issue: 13
Pages: 2521-32
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
27370713 | J:235629
First Author: Bondurand N
Year: 2016
Journal: Dev Biol
Title: Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new players.
Volume: 417
Issue: 2
Pages: 139-57
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Publication
30765420 | J:270567
     
First Author: Korecki AJ
Year: 2019
Journal: Genetics
Title: Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele.
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Publication
- | J:204202
     
First Author: The Pleiades Promoter and CanEuCre Project
Year: 2014
Journal: MGI Direct Data Submission
Title: Generation of reporter and cre-expressing targeted transgenic mice in the Hprt1 gene using human MiniPromoters that drive region- and cell-specific gene expression in the mouse brain
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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