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Search results 501 to 553 out of 553 for Stam

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Type Details Score
Publication
9407053 | J:44869
First Author: Asao H
Year: 1997
Journal: J Biol Chem
Title: Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth.
Volume: 272
Issue: 52
Pages: 32785-91
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Publication
9091585 | J:100736
First Author: Griffiths RJ
Year: 1997
Journal: J Exp Med
Title: Collagen-induced arthritis is reduced in 5-lipoxygenase-activating protein-deficient mice.
Volume: 185
Issue: 6
Pages: 1123-9
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Publication
37608393 | J:358976
First Author: van Heusden FC
Year: 2023
Journal: Alzheimers Res Ther
Title: Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes.
Volume: 15
Issue: 1
Pages: 142
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Publication
36997591 | J:335044
First Author: Oliveira-Stahl G
Year: 2023
Journal: Sci Rep
Title: High-precision spatial analysis of mouse courtship vocalization behavior reveals sex and strain differences.
Volume: 13
Issue: 1
Pages: 5219
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Publication
17010674 | J:114688
First Author: Wei G
Year: 2006
Journal: Cancer Cell
Title: Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.
Volume: 10
Issue: 4
Pages: 331-42
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Publication
18388320 | J:139593
First Author: Mukai A
Year: 2008
Journal: J Cell Sci
Title: Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis.
Volume: 121
Issue: Pt 8
Pages: 1325-33
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Publication
18598943 | J:150328
First Author: le Viseur C
Year: 2008
Journal: Cancer Cell
Title: In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
Volume: 14
Issue: 1
Pages: 47-58
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Publication
21187078 | -
First Author: Lim J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Solution structure of UIM and interaction of tandem ubiquitin binding domains in STAM1 with ubiquitin.
Volume: 405
Issue: 1
Pages: 24-30
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Publication
26101075 | J:226940
 
First Author: Kapuralin K
Year: 2015
Journal: Mol Cell Neurosci
Title: STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons.
Volume: 67
Pages: 104-15
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Protein Domain
IPR035657 | STAM1_SH3
Type: Domain
Description: This entry represents the SH3 domain of STAM1 (signal transducing adapter molecule 1). STAM1 is part of the endosomal sorting complex required for transport (ESCRT-0) and is involved in sorting ubiquitinated cargo proteins from the endosome []. It may also be involved in the regulation of IL2 and GM-CSF mediated signaling, and has been implicated in neural cell survival [, ]. STAMs were discovered as proteins that are highly phosphorylated following cytokine and growth factor stimulation []. They function in cytokine signaling and surface receptor degradation, as well as regulate Golgi morphology. They associate with many proteins including Jak2 and Jak3 tyrosine kinases [], Hrs, AMSH, and UBPY. STAM adaptor proteins contain VHS (Vps27, Hrs, STAM homology), ubiquitin interacting (UIM), and SH3 domains [].
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Protein Domain
IPR035675 | STAM2_SH3
Type: Domain
Description: This entry represents the SH3 domain of STAM2 (signal transducing adapter molecule 2). STAM2, a subunit of the ESCRT-0 complex, is an endosomal protein acting as a regulator of receptor signaling and trafficking. It contains an N-terminal VHS domain (Vps-27/Hrs/Stam), UIM (ubiquitin-interacting motif), SH3 (Src homology 3), CC ("coiled coil"), SSM (STAM-specific motif) and C-terminal ITAM (immunoreceptor tyrosine-based activation motif) domain. It may play a regulatory role in the endosomal sorting of ubiquitinated membrane proteins []. STAMs were discovered as proteins that are highly phosphorylated following cytokine and growth factor stimulation []. They function in cytokine signaling and surface receptor degradation, as well as regulate Golgi morphology. They associate with many proteins including Jak2 and Jak3 tyrosine kinases [], Hrs, AMSH, and UBPY. STAM adaptor proteins contain VHS (Vps27, Hrs, STAM homology), ubiquitin interacting (UIM), and SH3 domains [].
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Publication
11728436 | -
First Author: Lohi O
Year: 2001
Journal: FEBS Lett
Title: STAM/EAST/Hbp adapter proteins--integrators of signalling pathways.
Volume: 508
Issue: 3
Pages: 287-90
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Publication
12176364 | J:230362
First Author: Berry DM
Year: 2002
Journal: Curr Biol
Title: A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Volume: 12
Issue: 15
Pages: 1336-41
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Publication
19278655 | J:245341
First Author: Ren X
Year: 2009
Journal: Structure
Title: Hybrid structural model of the complete human ESCRT-0 complex.
Volume: 17
Issue: 3
Pages: 406-16
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Publication
37852976 | J:341628
First Author: Soeda K
Year: 2023
Journal: Nat Commun
Title: Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Volume: 14
Issue: 1
Pages: 6584
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Publication
27134167 | J:235481
First Author: Lau EY
Year: 2016
Journal: Cell Rep
Title: Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling.
Volume: 15
Issue: 6
Pages: 1175-89
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HT Experiment
E-GEOD-83596 | Hepatic transcriptomic changes during non-alcoholic steatohepatitis (NASH)-associated liver carcinogenesis in mice
Series Id: GSE83596
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
16458478 | J:114923
First Author: Chan WY
Year: 2006
Journal: Genomics
Title: The complexity of antisense transcription revealed by the study of developing male germ cells.
Volume: 87
Issue: 6
Pages: 681-92
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Publication
10329004 | J:54916
First Author: Seroussi E
Year: 1999
Journal: Genomics
Title: TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.
Volume: 57
Issue: 3
Pages: 380-8
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Publication
38720319 | J:352615
First Author: Xie Y
Year: 2024
Journal: Mol Cancer
Title: Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA(+) B cells.
Volume: 23
Issue: 1
Pages: 95
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Publication
15774496 | J:99850
First Author: Li LV
Year: 2005
Journal: Mol Endocrinol
Title: Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.
Volume: 19
Issue: 8
Pages: 2145-53
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Publication
36531991 | J:332254
 
First Author: Li T
Year: 2022
Journal: Front Immunol
Title: Akkermansia muciniphila suppressing nonalcoholic steatohepatitis associated tumorigenesis through CXCR6(+) natural killer T cells.
Volume: 13
Pages: 1047570
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Publication
39080409 | J:352530
First Author: Ohno T
Year: 2024
Journal: Sci Rep
Title: Periodontitis promotes hepatocellular carcinoma in Stelic Animal model (STAM) mice.
Volume: 14
Issue: 1
Pages: 17560
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Publication
25607821 | J:305895
First Author: Yoshimine Y
Year: 2015
Journal: Oncol Rep
Title: Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis.
Volume: 33
Issue: 4
Pages: 1657-66
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Publication
24983359 | J:218942
First Author: Ishikawa H
Year: 2014
Journal: PLoS One
Title: L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway.
Volume: 9
Issue: 7
Pages: e100627
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Publication
36333807 | J:360087
First Author: Li Z
Year: 2022
Journal: J Hematol Oncol
Title: JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis.
Volume: 15
Issue: 1
Pages: 161
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Protein Coding Gene
MGI:104681 | Hgs
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88811
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Protein
P70297
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q3TQ49
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q3UGN9
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q3UMC8
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
Q3TGH8
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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