Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_10 |
|
Specimen Label: |
euxassay_011464_10 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_11 |
|
Specimen Label: |
euxassay_011464_11 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_12 |
|
Specimen Label: |
euxassay_011464_12 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_13 |
|
Specimen Label: |
euxassay_011464_13 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_14 |
|
Specimen Label: |
euxassay_011464_14 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3233440 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4828546 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011464_15 |
|
Specimen Label: |
euxassay_011464_15 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crowder KM |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). |
Volume: |
96 |
Issue: |
26 |
Pages: |
15268-73 |
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•
•
•
•
•
|
Publication |
First Author: |
Custer KL |
Year: |
2006 |
Journal: |
J Neurosci |
Title: |
Synaptic vesicle protein 2 enhances release probability at quiescent synapses. |
Volume: |
26 |
Issue: |
4 |
Pages: |
1303-13 |
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•
•
•
•
|
Publication |
First Author: |
Nowack A |
Year: |
2010 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
SV2 regulates neurotransmitter release via multiple mechanisms. |
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Publication |
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Year: |
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Journal: |
J Neurosci |
Title: |
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Volume: |
29 |
Issue: |
4 |
Pages: |
883-97 |
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•
•
•
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Publication |
First Author: |
Xu T |
Year: |
2001 |
Journal: |
Nat Cell Biol |
Title: |
SV2 modulates the size of the readily releasable pool of secretory vesicles. |
Volume: |
3 |
Issue: |
8 |
Pages: |
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•
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Publication |
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Kaempf N |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles. |
Volume: |
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Issue: |
23 |
Pages: |
7297-302 |
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Journal: |
PLoS One |
Title: |
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Volume: |
8 |
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7 |
Pages: |
e68215 |
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•
•
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Publication |
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Neuron |
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Synaptotagmin 1-triggered lipid signaling facilitates coupling of exo- and endocytosis. |
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•
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Publication |
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Journal: |
J Neurosci |
Title: |
Cotrafficking of SV2 and synaptotagmin at the synapse. |
Volume: |
30 |
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16 |
Pages: |
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•
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Publication |
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Journal: |
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Pages: |
1-11 |
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Publication |
First Author: |
Sarria JC |
Year: |
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Journal: |
Cell Tissue Res |
Title: |
Developmental and spatial expression pattern of syntaxin 13 in the mouse central nervous system. |
Volume: |
309 |
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2 |
Pages: |
209-18 |
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•
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Publication |
First Author: |
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Year: |
2000 |
Journal: |
J Cell Biol |
Title: |
Agrin isoforms with distinct amino termini: differential expression, localization, and function. |
Volume: |
151 |
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1 |
Pages: |
41-52 |
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•
•
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Journal: |
J Comp Neurol |
Title: |
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Publication |
First Author: |
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Year: |
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Journal: |
Am J Respir Cell Mol Biol |
Title: |
Pulmonary neuroendocrine cells, airway innervation, and smooth muscle are altered in Cftr null mice. |
Volume: |
35 |
Issue: |
3 |
Pages: |
320-6 |
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•
•
•
•
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Publication |
First Author: |
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Year: |
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Journal: |
J Neurosci |
Title: |
Motoneuron survival is enhanced in the absence of neuromuscular junction formation in embryos. |
Volume: |
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Issue: |
9 |
Pages: |
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•
•
•
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Publication |
First Author: |
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Year: |
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Journal: |
Eur J Cell Biol |
Title: |
Synaptobrevin is essential for secretion but not for the development of synaptic processes. |
Volume: |
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1-11 |
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Publication |
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Year: |
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Journal: |
Cell |
Title: |
Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta. |
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J Comp Neurol |
Title: |
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531-40 |
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Publication |
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Year: |
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Journal: |
Development |
Title: |
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Neuron |
Title: |
The transcription factor Bhlhb4 is required for rod bipolar cell maturation. |
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Publication |
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Development |
Title: |
Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. |
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2398-408 |
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Multiple roles of integrin-α3 at the neuromuscular junction. |
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Title: |
Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor. |
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J Neurosci |
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DNA Res |
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Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
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Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
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Mouse Genome Informatics Scientific Curators |
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Title: |
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Database issue |
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Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
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Shanghai Model Organisms Center |
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MGI Direct Data Submission |
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Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
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Journal: |
MGI Direct Data Submission |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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UniProt-GOA |
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Title: |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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Mouse Genome Informatics Scientific Curators |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Database Download |
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MGI-UniGene Interconnection Effort |
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Title: |
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Mouse Genome Database and National Center for Biotechnology Information |
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Allen Institute for Brain Science |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Database Download |
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Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Dong M |
Year: |
2008 |
Journal: |
Mol Biol Cell |
Title: |
Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. |
Volume: |
19 |
Issue: |
12 |
Pages: |
5226-37 |
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Protein Domain |
Type: |
Family |
Description: |
SV2 proteins are abundant synaptic vesicle proteins expressed in two major (SV2A and SV2B) and one minor isoform (SV2C) that resemble transporter proteins. SV2B knockout mice are phenotypically normal while SV2A- and SV2A/SV2Bdouble knockout mice exhibit severe seizures and die postnatally. Without SV2 proteins, presynaptic Ca2+accumulation during consecutive action potentials causes abnormal increases in neurotransmitter release that destabilise synaptic circuits and induce epilepsy []. |
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Publication |
First Author: |
Tejero R |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy. |
Volume: |
25 |
Issue: |
21 |
Pages: |
4703-4716 |
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Publication |
First Author: |
Chakkalakal JV |
Year: |
2010 |
Journal: |
Development |
Title: |
Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons. |
Volume: |
137 |
Issue: |
20 |
Pages: |
3489-99 |
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Publication |
First Author: |
Dardou D |
Year: |
2011 |
Journal: |
Brain Res |
Title: |
Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system. |
Volume: |
1367 |
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Pages: |
130-45 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
358
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Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
742
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
683
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
727
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
667
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Fragment?: |
false |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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