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Search results 501 to 600 out of 626 for Tbk1

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Hits by Pathway

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Hits by Strain

Type Details Score
Strain
MGI:7490023 | C57BL/6N-Sting1<em2Zjc>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Ontology Term
- | Inhibition of host TLR pathway by virus
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Protein
Q05BS9
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Publication
25861989 | -
First Author: Wang W
Year: 2015
Journal: J Biol Chem
Title: TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
Volume: 290
Issue: 21
Pages: 13372-85
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Publication
22773835 | J:190237
First Author: Maruyama K
Year: 2012
Journal: J Biol Chem
Title: TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation.
Volume: 287
Issue: 34
Pages: 29114-24
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Protein Domain
IPR039669 | TANK
Type: Family
Description: TANK-binding kinase 1 (TBK1) and inducible IkappaB-kinase (IKK) are central regulators of type-I interferon induction. TANK (TRAF family member-associated NF-kappa-B activator) is aadaptor protein that connects IKK complexes with IKK epsilon and TBK1 kinases [, ]. It negatively regulates NF-kappaB activation by DNA damage via inhibiting ubiquitination of TRAF6 []. It is also a negative regulator of osteoclastogenesis and bone formation [].
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Protein
Q9R0T8
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
A1L361
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
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Protein
Q3U6P9
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
Q8CI55
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Protein
Q3THP3
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
E9PYL6
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Protein
A2AR78
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Publication
29429998 | J:287040
First Author: Liu Y
Year: 2018
Journal: Cell Mol Immunol
Title: ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association.
Volume: 15
Issue: 10
Pages: 907-916
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Publication
26928339 | J:259954
First Author: Zhou Y
Year: 2016
Journal: Nat Immunol
Title: The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3.
Volume: 17
Issue: 4
Pages: 397-405
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Publication
27086836 | J:233694
First Author: Meena NP
Year: 2016
Journal: FEBS Lett
Title: The TBK1-binding domain of optineurin promotes type I interferon responses.
Volume: 590
Issue: 10
Pages: 1498-508
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Publication
32346490 | -
First Author: Mirza MU
Year: 2020
Journal: J Pharm Anal
Title: Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase.
Volume: 10
Issue: 4
Pages: 320-328
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Publication
32875166 | -
 
First Author: Gurung AB
Year: 2020
Journal: Gene Rep
Title: In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors.
Volume: 21
Pages: 100860
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Publication
32529952 | -
First Author: Yuen CK
Year: 2020
Journal: Emerg Microbes Infect
Title: SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists.
Volume: 9
Issue: 1
Pages: 1418-1428
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Protein Domain
IPR044343 | NSP13_1B_dom_CoV
Type: Domain
Description: Helicase nonstructural protein 13 (NSP13) is encoded by the replicase polyprotein 1a/ab of coronaviruses and released after a proteolytic process. It plays a vital role in catalysing the unwinding of duplex oligonucleotides into single strands in an NTP-dependent manner. It is a multidomain protein which includes an N-terminal Cys/His rich zinc-binding domain (ZBD), followed by a stalk and 1B domains, and a helicase core that belongs to the superfamily SF1 of helicases, containing two RecA1 and RecA2 domains [, ]. The stalk region connects the ZBD domain and 1B domain. Nsp13 adopts a triangular pyramid shape in which the two RecA1 and A2 and 1B domain form the triangular base, while N-terminal ZBD and stalk domains are arranged at the apex of the pyramid [, , ]. Recently, it has been reported that SARS-CoV-2 NSP13 as an interferon antagonist. It is involved in type I interferon (IFN-I) response as it binds and blocks TBK1 phosphorylation to inhibit interferon regulatory factor 3 (IRF3) which results in decreased IRF3 activation [, ].This entry represents the 1B domain, which has a regulatory role modulating the nucleic acid substrate binding. Based on the structures from the related Equine arteritis virus (EAV) NSP10, it is likely that 1B domain forms a channel together with 1A and 2A domains that accommodates the single stranded nucleic acids [, ].
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Publication
24332030 | J:209295
First Author: Li X
Year: 2013
Journal: Immunity
Title: Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Volume: 39
Issue: 6
Pages: 1019-31
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Publication
30568238 | J:274853
     
First Author: Liu D
Year: 2018
Journal: Cell Death Differ
Title: STING directly activates autophagy to tune the innate immune response.
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Publication
25299331 | J:284987
First Author: Zhou Q
Year: 2014
Journal: Cell Host Microbe
Title: The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling.
Volume: 16
Issue: 4
Pages: 450-61
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Publication
23263557 | J:192611
First Author: Lee MN
Year: 2013
Journal: Nat Immunol
Title: Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.
Volume: 14
Issue: 2
Pages: 179-85
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Publication
38816352 | J:349100
First Author: Park JH
Year: 2024
Journal: Nat Commun
Title: Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression.
Volume: 15
Issue: 1
Pages: 4099
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Publication
30205046 | J:265468
First Author: Kitajima S
Year: 2018
Journal: Cancer Cell
Title: Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS.
Volume: 34
Issue: 3
Pages: 439-452.e6
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Publication
34707113 | J:314477
First Author: Banerjee D
Year: 2021
Journal: Nat Commun
Title: A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.
Volume: 12
Issue: 1
Pages: 6207
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Publication
28100675 | J:240737
First Author: Dalet A
Year: 2017
Journal: EMBO J
Title: Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Volume: 36
Issue: 6
Pages: 761-782
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Publication
28484079 | J:243950
First Author: Cerboni S
Year: 2017
Journal: J Exp Med
Title: Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.
Volume: 214
Issue: 6
Pages: 1769-1785
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Publication
17157040 | J:116705
First Author: An H
Year: 2006
Journal: Immunity
Title: SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.
Volume: 25
Issue: 6
Pages: 919-28
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Publication
24590060 | J:210522
First Author: Lam AR
Year: 2014
Journal: Cancer Res
Title: RAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.
Volume: 74
Issue: 8
Pages: 2193-2203
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Publication
34560002 | J:315700
First Author: Linares JF
Year: 2021
Journal: Mol Cell
Title: PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.
Volume: 81
Issue: 21
Pages: 4509-4526.e10
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Publication
24488098 | J:229349
First Author: Shostak K
Year: 2014
Journal: Cell Death Differ
Title: MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.
Volume: 21
Issue: 5
Pages: 811-24
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Publication
30853218 | J:286020
First Author: Tan Y
Year: 2019
Journal: Cell
Title: Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility.
Volume: 177
Issue: 2
Pages: 384-398.e11
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Publication
27438769 | J:258668
First Author: Zhang LJ
Year: 2016
Journal: Immunity
Title: Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury.
Volume: 45
Issue: 1
Pages: 119-30
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Publication
22902624 | J:191578
First Author: Enesa K
Year: 2012
Journal: J Biol Chem
Title: Pellino1 is required for interferon production by viral double-stranded RNA.
Volume: 287
Issue: 41
Pages: 34825-35
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Publication
29920190 | J:266602
First Author: Li F
Year: 2018
Journal: J Clin Invest
Title: HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection.
Volume: 128
Issue: 9
Pages: 4148-4162
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Publication
30943264 | J:285681
First Author: Ye L
Year: 2019
Journal: PLoS Pathog
Title: USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.
Volume: 15
Issue: 4
Pages: e1007680
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Publication
36943869 | J:349835
First Author: Jiang W
Year: 2023
Journal: Cell Rep
Title: UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS.
Volume: 42
Issue: 3
Pages: 112272
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Publication
28939760 | J:251075
First Author: Fang R
Year: 2017
Journal: J Immunol
Title: NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway.
Volume: 199
Issue: 9
Pages: 3222-3233
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Publication
36098982 | J:332171
First Author: Snelling T
Year: 2022
Journal: Biochem J
Title: Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.
Volume: 479
Issue: 20
Pages: 2195-2216
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Publication
34969857 | J:322222
 
First Author: Liu Z
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein PINLYP regulates type I interferon innate immunity.
Volume: 119
Issue: 1
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Publication
38127621 | J:351131
First Author: Cai X
Year: 2024
Journal: Cell Rep
Title: Factor inhibiting HIF negatively regulates antiviral innate immunity via hydroxylation of IKKϵ.
Volume: 43
Issue: 1
Pages: 113606
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Publication
21892174 | J:176439
First Author: Zhang Z
Year: 2011
Journal: Nat Immunol
Title: The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.
Volume: 12
Issue: 10
Pages: 959-65
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Publication
35013224 | J:322824
First Author: Li S
Year: 2022
Journal: Nat Commun
Title: Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation.
Volume: 13
Issue: 1
Pages: 105
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Publication
19933851 | J:157489
First Author: Boyd CR
Year: 2009
Journal: J Immunol
Title: Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.
Volume: 183
Issue: 12
Pages: 7703-9
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Publication
20363211 | J:163572
First Author: Tanaka H
Year: 2010
Journal: Arch Biochem Biophys
Title: The CagA protein of Helicobacter pylori suppresses the functions of dendritic cell in mice.
Volume: 498
Issue: 1
Pages: 35-42
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Publication
21042276 | J:170779
First Author: Shen RR
Year: 2011
Journal: Oncogene
Title: Emerging roles for the non-canonical IKKs in cancer.
Volume: 30
Issue: 6
Pages: 631-41
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Publication
39304793 | J:358061
First Author: Zhou R
Year: 2024
Journal: EMBO J
Title: TBK1-Zyxin signaling controls tumor-associated macrophage recruitment to mitigate antitumor immunity.
Volume: 43
Issue: 21
Pages: 4984-5017
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Publication
26900919 | J:247225
First Author: Chen W
Year: 2016
Journal: PLoS Pathog
Title: ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs.
Volume: 12
Issue: 2
Pages: e1005462
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Publication
28534493 | J:250595
 
First Author: Sun H
Year: 2017
Journal: Nat Commun
Title: USP13 negatively regulates antiviral responses by deubiquitinating STING.
Volume: 8
Pages: 15534
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Publication
33269343 | J:304433
First Author: Gong K
Year: 2020
Journal: Nat Cancer
Title: EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer.
Volume: 1
Issue: 4
Pages: 394-409
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Publication
36198273 | J:329912
First Author: Wang Y
Year: 2022
Journal: Cell Rep
Title: Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
Volume: 41
Issue: 1
Pages: 111434
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Publication
36223739 | J:345019
First Author: Liu H
Year: 2022
Journal: Cell Rep
Title: Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis.
Volume: 41
Issue: 2
Pages: 111469
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Publication
36972172 | J:348568
First Author: Kong L
Year: 2023
Journal: Cell Rep
Title: The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus.
Volume: 42
Issue: 4
Pages: 112306
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Publication
37595039 | J:344340
First Author: Kuang M
Year: 2023
Journal: Sci Adv
Title: XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility.
Volume: 9
Issue: 33
Pages: eadg5211
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Publication
37864796 | J:342680
First Author: Cao Y
Year: 2023
Journal: Cell Rep
Title: Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape.
Volume: 42
Issue: 10
Pages: 113262
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Publication
19926846 | J:155552
First Author: Saitoh T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.
Volume: 106
Issue: 49
Pages: 20842-6
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Publication
23669351 | J:199188
First Author: Minegishi Y
Year: 2013
Journal: Hum Mol Genet
Title: Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.
Volume: 22
Issue: 17
Pages: 3559-67
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Publication
16306936 | J:245346
First Author: Oganesyan G
Year: 2006
Journal: Nature
Title: Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response.
Volume: 439
Issue: 7073
Pages: 208-11
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Publication
16306937 | J:166021
First Author: Häcker H
Year: 2006
Journal: Nature
Title: Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.
Volume: 439
Issue: 7073
Pages: 204-7
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Publication
17618271 | J:123411
First Author: Takaoka A
Year: 2007
Journal: Nature
Title: DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
Volume: 448
Issue: 7152
Pages: 501-5
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Publication
18332133 | J:137585
First Author: Paun A
Year: 2008
Journal: J Biol Chem
Title: Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response.
Volume: 283
Issue: 21
Pages: 14295-308
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Publication
27103069 | J:233688
First Author: Sellier C
Year: 2016
Journal: EMBO J
Title: Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Volume: 35
Issue: 12
Pages: 1276-97
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Publication
30842662 | J:274355
First Author: Gui X
Year: 2019
Journal: Nature
Title: Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Volume: 567
Issue: 7747
Pages: 262-266
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Publication
32404352 | J:303177
First Author: Hoffpauir CT
Year: 2020
Journal: J Immunol
Title: TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection.
Volume: 205
Issue: 1
Pages: 153-167
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Publication
30944173 | J:280417
First Author: Dewi Pamungkas Putri D
Year: 2019
Journal: J Biol Chem
Title: PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.
Volume: 294
Issue: 21
Pages: 8412-8423
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Publication
22348129 | J:185326
First Author: Wang Z
Year: 2012
Journal: PLoS One
Title: SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells.
Volume: 7
Issue: 2
Pages: e31809
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Publication
34145038 | J:351860
First Author: Krenz B
Year: 2021
Journal: Cancer Res
Title: MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma.
Volume: 81
Issue: 16
Pages: 4242-4256
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Publication
23063435 | J:199742
First Author: Peschard P
Year: 2012
Journal: Curr Biol
Title: Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Volume: 22
Issue: 21
Pages: 2063-8
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Publication
32580962 | J:296305
First Author: Okamoto T
Year: 2020
Journal: Cancer Res
Title: FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function.
Volume: 80
Issue: 17
Pages: 3580-3592
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Publication
32645550 | J:321332
 
First Author: Li L
Year: 2020
Journal: Mol Immunol
Title: SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
Volume: 125
Pages: 51-62
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Publication
21949249 | J:177337
First Author: Clark K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.
Volume: 108
Issue: 41
Pages: 17093-8
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Publication
21625574 | J:176091
First Author: Gratz N
Year: 2011
Journal: PLoS Pathog
Title: Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.
Volume: 7
Issue: 5
Pages: e1001345
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Publication
23376065 | J:198056
First Author: Oussa NA
Year: 2013
Journal: Biochem Biophys Res Commun
Title: TRAF1 phosphorylation on Serine 139 modulates NF-κB activity downstream of 4-1BB in T cells.
Volume: 432
Issue: 1
Pages: 129-34
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Publication
26980762 | J:231761
First Author: Zhang X
Year: 2016
Journal: Cancer Res
Title: Analysis of Liver Tumor-Prone Mouse Models of the Hippo Kinase Scaffold Proteins RASSF1A and SAV1.
Volume: 76
Issue: 9
Pages: 2824-35
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Publication
26034202 | J:260823
First Author: Jiang X
Year: 2015
Journal: Hypertension
Title: Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophy.
Volume: 66
Issue: 2
Pages: 356-67
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Publication
28411188 | J:247671
First Author: Lai R
Year: 2017
Journal: J Immunol
Title: Raf Kinase Inhibitor Protein Preferentially Promotes TLR3-Triggered Signaling and Inflammation.
Volume: 198
Issue: 10
Pages: 4086-4095
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Publication
35394877 | J:352738
First Author: Hinkle JT
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Volume: 119
Issue: 15
Pages: e2118819119
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Publication
33459343 | J:305195
First Author: Malik AU
Year: 2021
Journal: Biochem J
Title: Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
Volume: 478
Issue: 3
Pages: 553-578
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Publication
30017954 | J:267043
 
First Author: Markovinovic A
Year: 2018
Journal: Neuroscience
Title: Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses.
Volume: 388
Pages: 139-151
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Publication
38142758 | J:353491
First Author: Wang L
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Volume: 1870
Issue: 3
Pages: 166997
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Publication
32581130 | J:291551
First Author: Sharma M
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease.
Volume: 117
Issue: 27
Pages: 15989-15999
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Publication
32709745 | J:293929
First Author: He X
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology.
Volume: 117
Issue: 32
Pages: 19465-19474
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Publication
27419230 | J:259873
First Author: Xiang W
Year: 2016
Journal: Sci Adv
Title: PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1.
Volume: 2
Issue: 7
Pages: e1501889
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Publication
36191211 | J:353327
First Author: Rodriguez DA
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Volume: 119
Issue: 41
Pages: e2207240119
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Publication
18922877 | J:197514
First Author: Pfaller CK
Year: 2008
Journal: J Virol
Title: Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.
Volume: 82
Issue: 24
Pages: 12365-73
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Publication
16394098 | J:111745
First Author: Yang K
Year: 2006
Journal: Mol Biol Cell
Title: Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells.
Volume: 17
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Pages: 1461-71
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First Author: Randall CM
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Journal: Proc Natl Acad Sci U S A
Title: Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus.
Volume: 111
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Pages: E265-72
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28188292 | J:241656
First Author: Hsia HC
Year: 2017
Journal: J Biol Chem
Title: Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity.
Volume: 292
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Pages: 5405-5417
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Publication
29618514 | J:264137
First Author: Motani K
Year: 2018
Journal: J Biol Chem
Title: Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
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32433485 | J:294209
First Author: Yu YQ
Year: 2020
Journal: Sci Rep
Title: PGAM5-MAVS interaction regulates TBK1/ IRF3 dependent antiviral responses.
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First Author: Khalil J
Year: 2020
Journal: Mol Cell Biol
Title: The Non-structural Protein NSs of SFTSV Causes Cytokine Storm Through the Hyper-activation of NF-κB.
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First Author: Liu X
Year: 2019
Journal: Cell Res
Title: Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling.
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First Author: Guo R
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Title: Rnf144b alleviates the inflammatory responses and cardiac dysfunction in sepsis.
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First Author: Peng YC
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Title: NAD activates olfactory receptor 1386 to regulate type I interferon responses in Plasmodium yoelii YM infection.
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Protein
P70347
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
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Protein
Q8C2D3
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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•
Protein
Q3UGW0
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
•
•
•
•
•
Protein
Q3TNB4
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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