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Search results 501 to 600 out of 650 for Tet2

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Type Details Score
Publication
27760115 | J:239417
First Author: Dai HQ
Year: 2016
Journal: Nature
Title: TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling.
Volume: 538
Issue: 7626
Pages: 528-532
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Publication
23920106 | J:202864
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
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Publication
24357321 | J:205485
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
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Publication
32892421 | J:306136
First Author: Manti M
Year: 2020
Journal: FASEB J
Title: Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.
Volume: 34
Issue: 11
Pages: 14440-14457
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Protein
Q4JK59
Organism: Mus musculus/domesticus
Length: 1912  
Fragment?: false
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
21741591 | J:174544
First Author: Holmfeldt L
Year: 2011
Journal: Cancer Cell
Title: The role of TET2 in hematologic neoplasms.
Volume: 20
Issue: 1
Pages: 1-2
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HT Experiment
GSE232920 | Effect of Tet2 deletion on gene expression in mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
30510015 | J:268225
First Author: Shingleton JR
Year: 2018
Journal: Cancer Discov
Title: TET2 Deficiency Sets the Stage for B-cell Lymphoma.
Volume: 8
Issue: 12
Pages: 1515-1517
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Protein
Q4JK59-3
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
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Protein
Q4JK59-2
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: false
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Protein
A0A0G2JGM1
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
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Publication
35962058 | J:344344
First Author: Burns SS
Year: 2022
Journal: Leukemia
Title: Il-1r1 drives leukemogenesis induced by Tet2 loss.
Volume: 36
Issue: 10
Pages: 2531-2534
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Publication
30944118 | J:276356
First Author: Jeong JJ
Year: 2019
Journal: Cancer Discov
Title: Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Volume: 9
Issue: 6
Pages: 778-795
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Publication
32929842 | J:301081
First Author: Li S
Year: 2020
Journal: EMBO Rep
Title: TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T-cell numbers.
Volume: 21
Issue: 10
Pages: e49425
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Interaction Experiment
Costa Y (2013)
Description: NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.
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HT Experiment
GSE212715 | Tet2 and Tet3 mediated active cytosine hydroxymethylation in Six2 progenitor cells is critical for nephron progenitor differentiation and nephron endowment
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
28416650 | J:242004
First Author: Ma S
Year: 2017
Journal: J Exp Med
Title: Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs.
Volume: 214
Issue: 5
Pages: 1471-1491
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Publication
37884767 | J:361270
First Author: Hong T
Year: 2023
Journal: Nat Aging
Title: TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells.
Volume: 3
Issue: 11
Pages: 1387-1400
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Publication
38062031 | J:343480
First Author: McClatchy J
Year: 2023
Journal: Nat Commun
Title: Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells.
Volume: 14
Issue: 1
Pages: 8102
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Publication
23827711 | J:199366
First Author: Song SJ
Year: 2013
Journal: Cell Stem Cell
Title: The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation.
Volume: 13
Issue: 1
Pages: 87-101
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Publication
32393787 | J:306095
     
First Author: Ji F
Year: 2020
Journal: Mol Psychiatry
Title: Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression.
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Allele
Tet2<tm1Smoc> | MGI:7292729
Name: tet methylcytosine dioxygenase 2; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
25582196 | J:224293
First Author: Sohni A
Year: 2015
Journal: Mol Cell Biol
Title: Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.
Volume: 35
Issue: 6
Pages: 1026-42
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HT Experiment
E-MTAB-10481 | RNA-seq of LSK isolated from Zrsr2 mutant, Tet2 mutant and Zrsr2/Tet2 double mutant against wild-type controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-MTAB-10486 | RNA-seq of LSK isolated from U2af1 mutant, Tet2 mutant and U2af1/Tet2 double mutant against wild-type controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:6354430 | B6.129-Tet2<tm1Smoc>/Smoc
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tet2<em1Smoc> | MGI:7292728
Name: tet methylcytosine dioxygenase 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6355246 | C57BL/6JSmoc-Tet2<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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HT Experiment
GSE142163 | Oocyte RNA-seq data of WT, Tet1-/- and Tet2-/-; RNA seq of PGC at E13.5
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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DO Term
DOID:0081068 | ST2 diffuse large B-cell lymphoma
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Protein
A0A087WP90
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Publication
27036965 | -
First Author: Rasmussen KD
Year: 2016
Journal: Genes Dev
Title: Role of TET enzymes in DNA methylation, development, and cancer.
Volume: 30
Issue: 7
Pages: 733-50
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Protein Domain
IPR040175 | TET1/2/3
Type: Family
Description: The pattern of DNA methylation at cytosine bases in the genome is tightly linked to gene expression []. TET proteins, including TET1/2/3, convert 5-methylcytosine to 5-hydroxymethylcytosine. They can also convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine []. They play roles in epigenetic regulation [, ]. Human TET2 mutations have been linked to various leukaemias. TET2 and TET3 interact with O-GlcNAc transferase (OGT) and promotes OGT-mediated GlcNAcylation []. The double epigenetic modifications on both DNA and histones by TET2 and OGT coordinate together for the regulation of gene transcription [].
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Protein
D0VLQ5
Organism: Mus musculus/domesticus
Length: 1921  
Fragment?: false
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Protein
Q8BNB2
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Protein
A0A5K1VVP6
Organism: Mus musculus/domesticus
Length: 1668  
Fragment?: false
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Protein
A0A0G2JF55
Organism: Mus musculus/domesticus
Length: 1920  
Fragment?: false
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Protein
Q80U11
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
G3UXI7
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
G3UZN8
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Protein
G3UZ35
Organism: Mus musculus/domesticus
Length: 399  
Fragment?: true
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Protein
A0A0G2JG87
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Publication
22975371 | J:192908
First Author: Shih AH
Year: 2012
Journal: Cancer Cell
Title: IDH1 mutations disrupt blood, brain, and barriers.
Volume: 22
Issue: 3
Pages: 285-7
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HT Experiment
GSE74938 | RNA-seq profiling of mouse PGC (Mus musculus)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE85674 | TET proteins regulate lineage specification and TCR-mediated expansion of iNKT cells (SMART-Seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE66832 | TET proteins regulate lineage specification and TCR-mediated expansion of iNKT cells (RNA-Seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-62594 | Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum
Series Id: GSE62594
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE172128 | Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture [bulk RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE212823 | DNA dioxygenases Tet2/3 control epithelial differentiation [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q8BG87
Organism: Mus musculus/domesticus
Length: 1803  
Fragment?: false
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Protein
Q3URK3
Organism: Mus musculus/domesticus
Length: 2007  
Fragment?: false
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Protein
E9Q9Y4
Organism: Mus musculus/domesticus
Length: 2039  
Fragment?: false
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Protein
D0VLQ4
Organism: Mus musculus/domesticus
Length: 2039  
Fragment?: false
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Publication
36848231 | J:340963
First Author: Brabson JP
Year: 2023
Journal: Cell Rep
Title: Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
Volume: 42
Issue: 1
Pages: 112027
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Publication
24114270 | J:201964
First Author: Fu X
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.
Volume: 110
Issue: 44
Pages: 17892-7
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Publication
23403289 | J:212599
First Author: Hahn MA
Year: 2013
Journal: Cell Rep
Title: Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.
Volume: 3
Issue: 2
Pages: 291-300
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Publication
22157888 | J:181117
First Author: Williams K
Year: 2011
Journal: EMBO Rep
Title: DNA methylation: TET proteins-guardians of CpG islands?
Volume: 13
Issue: 1
Pages: 28-35
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Publication
22980977 | J:187964
First Author: Lian CG
Year: 2012
Journal: Cell
Title: Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Volume: 150
Issue: 6
Pages: 1135-46
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Publication
22391558 | J:193374
First Author: Yang H
Year: 2013
Journal: Oncogene
Title: Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
Volume: 32
Issue: 5
Pages: 663-9
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Publication
24336466 | J:207899
 
First Author: Dan J
Year: 2013
Journal: Sci Rep
Title: Roles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells.
Volume: 3
Pages: 3492
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Publication
35256775 | J:355014
First Author: Chen LL
Year: 2022
Journal: Nat Cell Biol
Title: Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.
Volume: 24
Issue: 3
Pages: 353-363
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Publication
37643007 | J:341638
 
First Author: Li K
Year: 2023
Journal: J Clin Invest
Title: The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma.
Volume: 133
Issue: 20
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Publication
26928226 | J:356563
First Author: Bogdanović O
Year: 2016
Journal: Nat Genet
Title: Active DNA demethylation at enhancers during the vertebrate phylotypic period.
Volume: 48
Issue: 4
Pages: 417-26
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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