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Search results 501 to 600 out of 629 for Thrb

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Type Details Score
Publication
First Author: Liu Y
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Cone photoreceptor differentiation regulated by thyroid hormone transporter MCT8 in the retinal pigment epithelium.
Volume: 121
Issue: 30
Pages: e2402560121
Publication
First Author: Buenaventura DF
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors.
Volume: 60
Issue: 8
Pages: 2787-2799
Publication
First Author: Nakamura K
Year: 2006
Journal: J Neurosci Res
Title: Murine neocortical histogenesis is perturbed by prenatal exposure to low doses of Bisphenol A.
Volume: 84
Issue: 6
Pages: 1197-205
Publication
First Author: Selmi-Ruby S
Year: 2014
Journal: Endocrinology
Title: The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.
Volume: 155
Issue: 2
Pages: 635-46
Publication
First Author: Brzezinski JA 4th
Year: 2010
Journal: Development
Title: Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development.
Volume: 137
Issue: 4
Pages: 619-29
Publication
First Author: Bosze B
Year: 2020
Journal: J Neurosci
Title: Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance.
Volume: 40
Issue: 7
Pages: 1501-1513
Publication
First Author: Kanadia RN
Year: 2008
Journal: Development
Title: Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.
Volume: 135
Issue: 23
Pages: 3923-33
Publication
First Author: Yoon J
Year: 2014
Journal: J Biol Chem
Title: Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.
Volume: 289
Issue: 49
Pages: 34250-7
Publication  
First Author: Aavani T
Year: 2017
Journal: Gene Expr Patterns
Title: Temporal profiling of photoreceptor lineage gene expression during murine retinal development.
Volume: 23-24
Pages: 32-44
Publication
First Author: Luo H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.
Volume: 109
Issue: 9
Pages: E553-62
Publication
First Author: Jia L
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development.
Volume: 106
Issue: 41
Pages: 17534-9
Publication  
First Author: Muthu V
Year: 2019
Journal: Development
Title: Genomic architecture of Shh-dependent cochlear morphogenesis.
Volume: 146
Issue: 18
Publication
First Author: Poncet N
Year: 2020
Journal: EMBO Rep
Title: Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos.
Volume: 21
Issue: 1
Pages: e48469
Publication
First Author: Riesenberg AN
Year: 2009
Journal: J Neurosci
Title: Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.
Volume: 29
Issue: 41
Pages: 12865-77
Publication
First Author: Bosze B
Year: 2023
Journal: PLoS Genet
Title: Notch pathway mutants do not equivalently perturb mouse embryonic retinal development.
Volume: 19
Issue: 9
Pages: e1010928
Publication
First Author: Qiu F
Year: 2008
Journal: J Neurosci
Title: A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors.
Volume: 28
Issue: 13
Pages: 3392-403
Publication
First Author: Carmona MC
Year: 2002
Journal: J Biol Chem
Title: Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha.
Volume: 277
Issue: 24
Pages: 21489-98
Publication
First Author: Yamamoto H
Year: 2020
Journal: Cell Rep
Title: Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development.
Volume: 30
Issue: 3
Pages: 658-671.e5
Publication
First Author: Goetz JJ
Year: 2014
Journal: PLoS One
Title: Onecut1 and Onecut2 play critical roles in the development of the mouse retina.
Volume: 9
Issue: 10
Pages: e110194
Publication
First Author: Cai Z
Year: 2010
Journal: J Neurosci
Title: Temporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development.
Volume: 30
Issue: 11
Pages: 4110-9
Publication
First Author: Patel T
Year: 2022
Journal: Nat Commun
Title: Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro.
Volume: 13
Issue: 1
Pages: 5427
Publication
First Author: Ebeid M
Year: 2022
Journal: Dev Dyn
Title: PRDM16 expression and function in mammalian cochlear development.
Volume: 251
Issue: 10
Pages: 1666-1683
Publication
First Author: AlOgayil N
Year: 2021
Journal: Sci Rep
Title: Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver.
Volume: 11
Issue: 1
Pages: 13766
Publication
First Author: Liu S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis.
Volume: 117
Issue: 9
Pages: 5016-5027
Publication
First Author: Klimova L
Year: 2014
Journal: Development
Title: Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.
Volume: 141
Issue: 6
Pages: 1292-302
Publication
First Author: HƤgglund AC
Year: 2013
Journal: PLoS One
Title: Canonical Wnt/β-catenin signalling is essential for optic cup formation.
Volume: 8
Issue: 12
Pages: e81158
Publication
First Author: Sapkota D
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.
Volume: 111
Issue: 39
Pages: E4086-95
Publication  
First Author: Zheng MH
Year: 2009
Journal: Mol Brain
Title: The transcription factor RBP-J is essential for retinal cell differentiation and lamination.
Volume: 2
Pages: 38
Publication
First Author: Katoh K
Year: 2010
Journal: J Neurosci
Title: Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development.
Volume: 30
Issue: 19
Pages: 6515-26
Publication
First Author: Katoh K
Year: 2012
Journal: J Neurosci
Title: G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.
Volume: 32
Issue: 49
Pages: 17658-70
Publication
First Author: Pei L
Year: 2011
Journal: Nat Med
Title: Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.
Volume: 17
Issue: 11
Pages: 1466-72
Publication  
First Author: Martinez ME
Year: 2021
Journal: Front Neurosci
Title: The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain.
Volume: 15
Pages: 703730
Publication
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
Publication
First Author: Choi MY
Year: 2006
Journal: Development
Title: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
Volume: 133
Issue: 20
Pages: 4119-29
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Regulatory Region
Type: intronic_regulatory_region
Organism: mouse, laboratory
Allele
Name: thyroid hormone receptor beta; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5309175
Age: embryonic day 18.0
Note: In the spiral ganglion, expression was detected in a neuron-like pattern and partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B E18
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5309175
Age: postnatal day 3
Note: In the spiral ganglion, expression was detected in a neuron-like pattern and partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P3
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 5
Note: In the spiral ganglion, expression was detected in a neuron-like pattern and partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 7
Note: In the spiral ganglion, expression was detected in a neuron-like pattern and partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P7
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 10
Note: In the spiral ganglion, expression was detected in a neuron-like pattern and declined after P7. The expression partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 7
Note: Signals were at lower levels in the lesser epithelial ridge. In the greater epithelial ridge, the expression pattern partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P7
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 10
Note: Signals were at lower levels in the lesser epithelial ridge. In the greater epithelial ridge, the expression pattern partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B P10
Detected: true
Specimen Num: 5
DO Term
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1906126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5309175
Age: embryonic day 18.0
Note: Signals were detected in the greater epithelial ridge and at lower levels in the lesser epithelial ridge. In the greater epithelial ridge, the expression pattern partly overlapped with that of Thrb (see assay MGI:5311181).
Specimen Label: 1B E18
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5309175
Age: postnatal day 3
Note: Signals were at lower levels in the lesser epithelial ridge. In the greater epithelial ridge, the expression pattern partly overlapped with that of Thrb (see assay MGI:5311181) and decreased as the tissue was lost between P3 and P15.
Specimen Label: 1B P3
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5308757
Assay Type: RNA in situ
Annotation Date: 2012-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5309175
Age: postnatal day 5
Note: Signals were at lower levels in the lesser epithelial ridge. In the greater epithelial ridge, the expression pattern partly overlapped with that of Thrb (see assay MGI:5311181) and decreased as the tissue was lost between P3 and P15.
Specimen Label: 1B P5
Detected: true
Specimen Num: 3
Allele
Name: thyroid hormone receptor alpha; targeted mutation 1, Sheue-yann Cheng
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Tomaru T
Year: 2006
Journal: Endocrinology
Title: Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma.
Volume: 147
Issue: 1
Pages: 377-88
Protein Domain
Type: Family
Description: Helicase with zinc finger domain 2 (HELZ2) is a helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA []. It interacts with THRAP3 (thyroid hormone receptor-associated protein3), a putative component of the Mediator complex that plays a role in adipocyte differentiation [].
Publication
First Author: Kaneshige M
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A targeted dominant negative mutation of the thyroid hormone alpha 1 receptor causes increased mortality, infertility, and dwarfism in mice.
Volume: 98
Issue: 26
Pages: 15095-100
Publication
First Author: Bassett JH
Year: 2014
Journal: Endocrinology
Title: Thyroid hormone receptor α mutation causes a severe and thyroxine-resistant skeletal dysplasia in female mice.
Volume: 155
Issue: 9
Pages: 3699-712
Publication
First Author: Ying H
Year: 2007
Journal: Mol Cell Biol
Title: Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor.
Volume: 27
Issue: 6
Pages: 2359-71
Publication
First Author: Park S
Year: 2017
Journal: PLoS Genet
Title: Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene.
Volume: 13
Issue: 9
Pages: e1006991
Publication
First Author: Aguiari P
Year: 2021
Journal: Sci Rep
Title: Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha.
Volume: 11
Issue: 1
Pages: 4601
Allele  
Name: neural retina leucine zipper gene; targeted mutation 1.1, Douglas Forrest
Allele Type: Targeted
Allele
Name: transgene insertion, Lian Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: regulatory region 468; targeted mutation 1.1, Douglas Forrest
Allele Type: Targeted
Attribute String: Modified regulatory region
Allele
Name: regulatory region 468; targeted mutation 2.1, Douglas Forrest
Allele Type: Targeted
Attribute String: Modified regulatory region
Allele
Name: regulatory region 468; targeted mutation 3.1, Douglas Forrest
Allele Type: Targeted
Attribute String: Modified regulatory region
Genotype
Symbol: Thra/Thra<+>
Background: involves: 129S6/SvEvTac
Zygosity: ht
Has Mutant Allele: true