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Search results 501 to 600 out of 624 for Tpm1

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Type Details Score
Publication
30700554 | J:280323
First Author: Cho E
Year: 2019
Journal: J Biol Chem
Title: Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.
Volume: 294
Issue: 13
Pages: 4981-4996
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Publication
30642949 | J:294106
 
First Author: Soulez M
Year: 2019
Journal: Mol Cell Biol
Title: Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models.
Volume: 39
Issue: 6
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Publication
22267199 | J:181488
First Author: Delgado-OlguĂ­n P
Year: 2012
Journal: Nat Genet
Title: Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.
Volume: 44
Issue: 3
Pages: 343-7
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Publication
29555813 | J:259848
 
First Author: Chal J
Year: 2018
Journal: Development
Title: Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.
Volume: 145
Issue: 6
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Publication
21311046 | J:178290
First Author: del Monte G
Year: 2011
Journal: Circ Res
Title: Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.
Volume: 108
Issue: 7
Pages: 824-36
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Publication
31024170 | J:331853
First Author: Gao R
Year: 2019
Journal: Cell Res
Title: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.
Volume: 29
Issue: 6
Pages: 486-501
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Publication
23236519 | J:195548
First Author: Brody MJ
Year: 2012
Journal: PLoS One
Title: Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.
Volume: 7
Issue: 12
Pages: e51621
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Publication
38196272 | J:347631
First Author: Li C
Year: 2024
Journal: Adv Sci (Weinh)
Title: Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.
Volume: 11
Issue: 11
Pages: e2305992
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Publication
14595844 | J:86589
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
33661765 | J:308949
 
First Author: Pham AK
Year: 2021
Journal: JCI Insight
Title: ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility.
Volume: 6
Issue: 7
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Allele
Tg(Myh6-Tpm1*D230N)HJcf | MGI:6256754
Name: transgene insertion H, Jil C Tardiff
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Tpm1*D230N)HJcf/?
Background: B6.FVB-Tg(Myh6-Tpm1*D230N)HJcf
Zygosity: ot
Has Mutant Allele: true
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QTL
MGI:108026 | Tcpm1
Type: QTL
Organism: mouse, laboratory
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Publication
12808144 | -
First Author: Singer JM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.
Volume: 100
Issue: 13
Pages: 7644-9
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Publication
7844152 | -
First Author: Drees B
Year: 1995
Journal: J Cell Biol
Title: Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions.
Volume: 128
Issue: 3
Pages: 383-92
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Allele
Tg(Myh6-Tpm1*E54K)30Dfw | MGI:5906016
Name: transgene insertion 30, David F Wieczorek
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Myh6-Tpm1*E54K)67Dfw | MGI:5906017
Name: transgene insertion 67, David F Wieczorek
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Transgene
MGI:5906014 | Tg(Myh6-Tpm1*E54K)30Dfw
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5906015 | Tg(Myh6-Tpm1*E54K)67Dfw
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:6256753 | Tg(Myh6-Tpm1*D230N)HJcf
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Myh6-Tpm1*E54K)30Dfw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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DO Term
DOID:0110457 | dilated cardiomyopathy 1Y
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Genotype
Genotype
Symbol: Tg(Myh6-Tpm1*E54K)67Dfw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Publication
24876965 | -
 
First Author: Dube S
Year: 2014
Journal: Mol Biol Int
Title: Expression of TPM1Îş, a Novel Sarcomeric Isoform of the TPM1 Gene, in Mouse Heart and Skeletal Muscle.
Volume: 2014
Pages: 896068
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Allele
Tln2<em1Clo> | MGI:6879498
Name: talin 2; endonuclease-mediated mutation 1, Cecilia Lo
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Strain
MGI:6256756 | B6.FVB-Tg(Myh6-Tpm1*D230N)HJcf
Attribute String: transgenic, mutant strain, congenic
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Protein
Q8BKI9
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: true
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Protein
Q8BY54
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: true
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Protein Domain
IPR019183 | N-acetylTrfase_B_cplx_non-cat
Type: Family
Description: This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyses the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae (Baker's yeast) this subunit is called MDM20 and in Schizosaccharomyces pombe (Fission yeast) it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1 [].
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Genotype
Genotype
Symbol: Tln2/Tln2<+> Tpm1/Tpm1<+>
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Publication
29510160 | J:258198
 
First Author: Shibata T
Year: 2018
Journal: Mech Ageing Dev
Title: Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity.
Volume: 171
Pages: 24-30
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Publication
23885106 | J:356360
First Author: Xiao S
Year: 2014
Journal: Reprod Sci
Title: Differential gene expression profiling of mouse uterine luminal epithelium during periimplantation.
Volume: 21
Issue: 3
Pages: 351-62
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Protein
P21107
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Protein
P58771
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
P58774
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
Q8BP43
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
Q545Y3
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
G5E8R0
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
E9Q454
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
E9Q456
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
Q9D1R6
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
A2AIM5
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
Q91VH3
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
E9Q455
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Protein
A0A0R4J1P2
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
E9Q452
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
D3Z6I8
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Protein
Q8C7C3
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
E9Q453
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
S4R2U0
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
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Protein
E9Q7Q3
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
A2AIM4
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
A0A2R2Y2P8
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
D3YVR0
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
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Protein
Q8BSH3
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Publication
3606587 | -
First Author: MacLeod AR
Year: 1987
Journal: Bioessays
Title: Genetic origin of diversity of human cytoskeletal tropomyosins.
Volume: 6
Issue: 5
Pages: 208-12
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Publication
6993480 | -
First Author: Lewis WG
Year: 1980
Journal: J Biol Chem
Title: The amino acid sequence of rabbit cardiac tropomyosin.
Volume: 255
Issue: 14
Pages: 6854-9
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Publication
12690456 | -
First Author: Wolska BM
Year: 2003
Journal: Pflugers Arch
Title: The role of tropomyosin in the regulation of myocardial contraction and relaxation.
Volume: 446
Issue: 1
Pages: 1-8
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Protein Domain
IPR000533 | Tropomyosin
Type: Family
Description: Tropomyosins [], are a family of closely related proteins present in muscle and non-muscle cells. In striated muscle, tropomyosin mediate the interactions between the troponin complex and actin so as to regulate muscle contraction []. The role of tropomyosin in smooth muscle and non-muscle tissues is not clear. Tropomyosin is an α-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites []. There are multiple cell-specific isoforms, created by differential splicing of the messenger RNA from one gene, but the proportions of the isoforms vary between different cell types. Muscle isoforms of tropomyosin are characterised by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.This entry represents tropomyosin (Tmp) 1, 2 and 3. Within the yeast Tmp1 and Tmp2, biochemical and sequence analyses indicate that Tpm2 spans four actin monomers along a filament, whereas Tpm1 spans five. Despite its shorter length, Tpm2 can compete with Tpm1 for binding to F-actin. Over-expression of Tpm2 in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis [].
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Publication
9973388 | J:53010
First Author: Guler ML
Year: 1999
Journal: J Immunol
Title: Tpm1, a locus controlling IL-12 responsiveness, acts by a cell-autonomous mechanism.
Volume: 162
Issue: 3
Pages: 1339-47
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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