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Search results 501 to 600 out of 766 for Vav1

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI:106211 | Cdc42
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1339975 | Pak1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P60766
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
O88643
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: false
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Protein
P39688
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: false
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Protein Coding Gene
MGI:97845 | Rac1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P63001
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Publication
16710471 | J:110372
First Author: Wong PK
Year: 2006
Journal: J Clin Invest
Title: SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis.
Volume: 116
Issue: 6
Pages: 1571-81
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Publication
27317261 | J:254914
First Author: Masamoto Y
Year: 2016
Journal: Immunity
Title: Adiponectin Enhances Antibacterial Activity of Hematopoietic Cells by Suppressing Bone Marrow Inflammation.
Volume: 44
Issue: 6
Pages: 1422-33
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Publication
23552075 | J:205746
 
First Author: Taniguchi Ishikawa E
Year: 2013
Journal: Nat Commun
Title: Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking.
Volume: 4
Pages: 1660
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Publication
21653884 | J:173454
First Author: Sengupta A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
Volume: 108
Issue: 24
Pages: 9957-62
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Publication
29650642 | J:314830
First Author: Zhou Y
Year: 2018
Journal: Haematologica
Title: Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation.
Volume: 103
Issue: 7
Pages: 1110-1123
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Publication
22498741 | J:185148
First Author: Gonzalez-Nieto D
Year: 2012
Journal: Blood
Title: Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors.
Volume: 119
Issue: 22
Pages: 5144-54
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Publication
17510322 | J:145513
First Author: Boyle K
Year: 2007
Journal: Blood
Title: The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo.
Volume: 110
Issue: 5
Pages: 1466-74
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Publication
25855602 | J:222624
First Author: Krock BL
Year: 2015
Journal: Blood
Title: The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.
Volume: 125
Issue: 21
Pages: 3263-72
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Publication
24408928 | J:209155
First Author: Shay JE
Year: 2014
Journal: Carcinogenesis
Title: Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer.
Volume: 35
Issue: 5
Pages: 1067-77
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Publication
18400361 | J:136891
First Author: Croker BA
Year: 2008
Journal: Exp Hematol
Title: Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation.
Volume: 36
Issue: 7
Pages: 786-98
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Publication
31515251 | J:282181
First Author: Park CS
Year: 2019
Journal: Blood
Title: A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells.
Volume: 134
Issue: 22
Pages: 1960-1972
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Publication
31379128 | J:290330
First Author: Schuler F
Year: 2019
Journal: EMBO Rep
Title: Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.
Volume: 20
Issue: 8
Pages: e47026
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Publication
32479500 | J:289626
First Author: Spivak JL
Year: 2020
Journal: PLoS One
Title: Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera.
Volume: 15
Issue: 6
Pages: e0232801
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Publication
24574460 | J:210744
First Author: Taylor A
Year: 2014
Journal: Blood
Title: SRF is required for neutrophil migration in response to inflammation.
Volume: 123
Issue: 19
Pages: 3027-36
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Publication
26165925 | J:356846
First Author: Cai X
Year: 2015
Journal: Cell Stem Cell
Title: Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells.
Volume: 17
Issue: 2
Pages: 165-77
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Publication
34661963 | J:317195
First Author: Kandi R
Year: 2021
Journal: EMBO Rep
Title: Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.
Volume: 22
Issue: 12
Pages: e52931
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Publication
35011611 | J:333642
 
First Author: Buks R
Year: 2021
Journal: Cells
Title: Altered Ca(2+) Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis.
Volume: 11
Issue: 1
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Publication
30156910 | J:285903
First Author: Korovina I
Year: 2019
Journal: FASEB J
Title: Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.
Volume: 33
Issue: 2
Pages: 1758-1770
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Publication
32675226 | J:350025
First Author: Warsi S
Year: 2021
Journal: Haematologica
Title: BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal.
Volume: 106
Issue: 8
Pages: 2203-2214
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Publication
30366956 | J:267689
First Author: Chaves P
Year: 2018
Journal: J Immunol
Title: Loss of Canonical Notch Signaling Affects Multiple Steps in NK Cell Development in Mice.
Volume: 201
Issue: 11
Pages: 3307-3319
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Publication
22261438 | J:181305
First Author: Gordon SM
Year: 2012
Journal: Immunity
Title: The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation.
Volume: 36
Issue: 1
Pages: 55-67
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Publication
36110849 | J:330835
 
First Author: Hutter K
Year: 2022
Journal: Front Immunol
Title: The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression.
Volume: 13
Pages: 967914
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Publication
27507714 | J:241264
 
First Author: Wang W
Year: 2016
Journal: Nat Commun
Title: MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis.
Volume: 7
Pages: 12376
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Publication
27076172 | J:234799
First Author: Behrens K
Year: 2016
Journal: Blood
Title: Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions.
Volume: 127
Issue: 26
Pages: 3369-81
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Publication
21741597 | J:193161
First Author: Bernt KM
Year: 2011
Journal: Cancer Cell
Title: MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Volume: 20
Issue: 1
Pages: 66-78
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Publication
32572036 | J:293768
First Author: Seitz V
Year: 2020
Journal: Sci Rep
Title: Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL.
Volume: 10
Issue: 1
Pages: 10024
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Publication
28213513 | J:241527
First Author: Behrens K
Year: 2017
Journal: J Exp Med
Title: RUNX1 cooperates with FLT3-ITD to induce leukemia.
Volume: 214
Issue: 3
Pages: 737-752
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Publication
35697791 | J:326986
First Author: Wei Y
Year: 2022
Journal: Leukemia
Title: Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia.
Volume: 36
Issue: 8
Pages: 2097-2107
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Publication
27298444 | J:236255
First Author: Antignano F
Year: 2016
Journal: J Exp Med
Title: G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program.
Volume: 213
Issue: 7
Pages: 1153-62
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Publication
24532712 | J:209140
First Author: Lehnertz B
Year: 2014
Journal: Genes Dev
Title: The methyltransferase G9a regulates HoxA9-dependent transcription in AML.
Volume: 28
Issue: 4
Pages: 317-27
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Publication
26302753 | J:242872
First Author: Rovira-Clavé X
Year: 2016
Journal: J Leukoc Biol
Title: Dual role of ERK5 in the regulation of T cell receptor expression at the T cell surface.
Volume: 99
Issue: 1
Pages: 143-52
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Publication
34006870 | J:306092
First Author: Carr RM
Year: 2021
Journal: Nat Commun
Title: RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Volume: 12
Issue: 1
Pages: 2901
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Publication
30024857 | J:266380
First Author: Edelmann B
Year: 2018
Journal: J Clin Invest
Title: JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Volume: 128
Issue: 10
Pages: 4359-4371
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Publication
30651633 | J:274256
First Author: Guo Y
Year: 2019
Journal: Leukemia
Title: ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis.
Volume: 33
Issue: 5
Pages: 1287-1291
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Publication
35286385 | J:326022
First Author: Li L
Year: 2022
Journal: Blood
Title: HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Volume: 139
Issue: 18
Pages: 2797-2815
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Publication
34780480 | J:320200
First Author: Tian L
Year: 2021
Journal: PLoS One
Title: Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype.
Volume: 16
Issue: 11
Pages: e0255706
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Publication
35091680 | J:322711
First Author: Chen TC
Year: 2022
Journal: Oncogene
Title: Oncogenesis induced by combined Phf6 and Idh2 mutations through increased oncometabolites and impaired DNA repair.
Volume: 41
Issue: 11
Pages: 1576-1588
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Publication
28728747 | J:244102
First Author: Erba BG
Year: 2017
Journal: Am J Pathol
Title: Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.
Volume: 187
Issue: 8
Pages: 1879-1892
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Publication
27185381 | J:278594
First Author: Perez-Cunningham J
Year: 2016
Journal: Exp Hematol
Title: Hematopoietic stem cell-specific GFP-expressing transgenic mice generated by genetic excision of a pan-hematopoietic reporter gene.
Volume: 44
Issue: 8
Pages: 755-764.e1
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Genotype
Genotype
Symbol: Socs3/Socs3 Tg(Vav1-cre)1Awr/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1 Tg(VAV1-cre)1Graf/?
Background: involves: 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Etv6/Etv6<+> Tg(VAV1-cre)1Graf/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ehmt2/Ehmt2 Tg(VAV1-cre)1Graf/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rapgef2/Rapgef2 Tg(VAV1-cre)1Graf/?
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ncstn/Ncstn Tg(VAV1-cre)1Graf/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tet2/Tet2<+> Tg(VAV1-cre)1Graf/?
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tet2/Tet2 Tg(VAV1-cre)1Graf/?
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dot1l/Dot1l Tg(VAV1-cre)1Graf/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Plvap/Plvap Tg(VAV1-cre)1Graf/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Ezh1/Ezh1 Tg(VAV1-cre)1Graf/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh1/Ezh1 Tg(VAV1-cre)1Graf/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptpmt1/Ptpmt1 Tg(VAV1-cre)1Graf/?
Background: involves: 129S6/SvEvTac * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccbe1/Ccbe1 Tg(VAV1-cre)1Graf/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ncstn/Ncstn Tg(VAV1-cre)1Graf/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcr/Bcr<+> Runx1/Runx1<+> Tg(Vav1-cre)#Cgp/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jak2/Jak2<+> Tg(Vav1-cre)#Cgp/?
Background: involves: 129S2/SvPas * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Asxl1/Asxl1 Tg(VAV1-cre)1Graf/?
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Asxl1/Asxl1 Tet2/Tet2 Tg(VAV1-cre)1Graf/?
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nbn/Nbn Tg(VAV1-cre)1Graf/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atm/Atm Tg(VAV1-cre)1Graf/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Vav1-cre)8Cgp/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Vav1-cre)1Cgp/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Vav1-cre)1Awr/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(VAV1-cre)1Graf/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(VAV1-cre)1Graf/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm2b/Kdm2b Tg(VAV1-cre)1Graf/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chd7/Chd7 Tg(VAV1-cre)1Graf/?
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1 Tg(VAV1-cre)1Graf/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1 Tg(VAV1-cre)1Graf/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
27016526 | J:259523
First Author: Srikanth S
Year: 2016
Journal: Sci Signal
Title: A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals.
Volume: 9
Issue: 420
Pages: ra31
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Publication
23696226 | J:201200
First Author: Hosomi S
Year: 2013
Journal: Eur J Immunol
Title: CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
Volume: 43
Issue: 9
Pages: 2473-83
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Publication
22422825 | J:185179
First Author: Lai JC
Year: 2012
Journal: Blood
Title: The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis.
Volume: 119
Issue: 18
Pages: 4291-300
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Publication
25477210 | J:230916
First Author: Chiang YJ
Year: 2015
Journal: Int Immunol
Title: Regulation of T cell development by c-Cbl: essential role of Lck.
Volume: 27
Issue: 5
Pages: 245-51
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Publication
22043008 | J:179722
First Author: Mondal S
Year: 2011
Journal: J Immunol
Title: PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.
Volume: 187
Issue: 11
Pages: 5783-94
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Publication
30674283 | J:294500
First Author: Zhang Z
Year: 2019
Journal: BMC Immunol
Title: CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes.
Volume: 20
Issue: 1
Pages: 7
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Publication
25977335 | J:222933
First Author: Razidlo GL
Year: 2015
Journal: Cancer Res
Title: Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion.
Volume: 75
Issue: 14
Pages: 2907-15
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Publication
27893715 | J:241235
First Author: Huang PH
Year: 2017
Journal: Oncogene
Title: TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.
Volume: 36
Issue: 16
Pages: 2202-2214
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Publication
23325840 | J:195880
First Author: ten Hacken E
Year: 2013
Journal: Blood
Title: Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia.
Volume: 121
Issue: 12
Pages: 2264-73
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Publication
22815290 | J:189733
First Author: Chen G
Year: 2012
Journal: J Immunol
Title: The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation.
Volume: 189
Issue: 5
Pages: 2138-50
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Publication
23620790 | J:200103
First Author: Chiang YJ
Year: 2013
Journal: PLoS One
Title: CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
Volume: 8
Issue: 4
Pages: e61761
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Publication
15576379 | J:96907
First Author: Simon M
Year: 2005
Journal: J Biol Chem
Title: Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells.
Volume: 280
Issue: 6
Pages: 4510-7
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Publication
17339487 | J:144271
First Author: Fumagalli L
Year: 2007
Journal: J Immunol
Title: The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine.
Volume: 178
Issue: 6
Pages: 3874-85
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Publication
19917685 | J:157515
First Author: Carrizosa E
Year: 2009
Journal: J Immunol
Title: Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreading.
Volume: 183
Issue: 11
Pages: 7352-61
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Publication
24368807 | J:208276
First Author: Montresor A
Year: 2013
Journal: J Cell Biol
Title: JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation.
Volume: 203
Issue: 6
Pages: 1003-19
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Publication
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