| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1309
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
907
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
775
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
491
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1095
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1624
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1214
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamanaka H |
| Year: |
2002 |
| Journal: |
Brain Res Gene Expr Patterns |
| Title: |
Expression of Apc2 during mouse development. |
| Volume: |
1 |
| Issue: |
2 |
| Pages: |
107-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ling H |
| Year: |
2013 |
| Journal: |
Cancer Res |
| Title: |
Cyclin D1-dependent induction of luminal inflammatory breast tumors by activated notch3. |
| Volume: |
73 |
| Issue: |
19 |
| Pages: |
5963-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Capone C |
| Year: |
2016 |
| Journal: |
Ann Neurol |
| Title: |
Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice. |
| Volume: |
79 |
| Issue: |
3 |
| Pages: |
387-403 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jespersen K |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
10949 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang M |
| Year: |
2015 |
| Journal: |
Apoptosis |
| Title: |
Notch3/Akt signaling contributes to OSM-induced protection against cardiac ischemia/reperfusion injury. |
| Volume: |
20 |
| Issue: |
9 |
| Pages: |
1150-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ratelade J |
| Year: |
2020 |
| Journal: |
Circulation |
| Title: |
Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. |
| Volume: |
141 |
| Issue: |
25 |
| Pages: |
2078-2094 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Canalis E |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
The lateral meningocele syndrome mutation causes marked osteopenia in mice. |
| Volume: |
293 |
| Issue: |
36 |
| Pages: |
14165-14177 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Klein-Hessling S |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development. |
| Volume: |
7 |
|
| Pages: |
11841 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morrison SJ |
| Year: |
2002 |
| Journal: |
J Immunol |
| Title: |
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. |
| Volume: |
168 |
| Issue: |
2 |
| Pages: |
635-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Del Gaudio F |
| Year: |
2023 |
| Journal: |
Sci Rep |
| Title: |
Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
15022 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao N |
| Year: |
2015 |
| Journal: |
Circ Res |
| Title: |
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells. |
| Volume: |
116 |
| Issue: |
1 |
| Pages: |
23-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chalkidi N |
| Year: |
2026 |
| Journal: |
Commun Biol |
| Title: |
Notch3 regulates pericyte phenotypic plasticity in colorectal cancer. |
| Volume: |
9 |
| Issue: |
1 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Domenga V |
| Year: |
2004 |
| Journal: |
Genes Dev |
| Title: |
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. |
| Volume: |
18 |
| Issue: |
22 |
| Pages: |
2730-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baeten JT |
| Year: |
2015 |
| Journal: |
J Biol Chem |
| Title: |
Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells. |
| Volume: |
290 |
| Issue: |
26 |
| Pages: |
16226-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lundkvist J |
| Year: |
2005 |
| Journal: |
Genesis |
| Title: |
Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype. |
| Volume: |
41 |
| Issue: |
1 |
| Pages: |
13-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Campese AF |
| Year: |
2009 |
| Journal: |
Int Immunol |
| Title: |
Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells. |
| Volume: |
21 |
| Issue: |
6 |
| Pages: |
727-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dabertrand F |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease. |
| Volume: |
112 |
| Issue: |
7 |
| Pages: |
E796-805 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruchoux MM |
| Year: |
2003 |
| Journal: |
Am J Pathol |
| Title: |
Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. |
| Volume: |
162 |
| Issue: |
1 |
| Pages: |
329-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Talora C |
| Year: |
2003 |
| Journal: |
EMBO Rep |
| Title: |
Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma. |
| Volume: |
4 |
| Issue: |
11 |
| Pages: |
1067-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brahim S |
| Year: |
2023 |
| Journal: |
Cell Death Dis |
| Title: |
Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer. |
| Volume: |
14 |
| Issue: |
2 |
| Pages: |
171 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo W |
| Year: |
2021 |
| Journal: |
Nature |
| Title: |
Arterialization requires the timely suppression of cell growth. |
| Volume: |
589 |
| Issue: |
7842 |
| Pages: |
437-441 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3644
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3620
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3643
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1789
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Idowu J |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
3340 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumar P |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Soluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signaling. |
| Volume: |
7 |
|
| Pages: |
39751 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Varga J |
| Year: |
2020 |
| Journal: |
J Exp Med |
| Title: |
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer. |
| Volume: |
217 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng Y |
| Year: |
2013 |
| Journal: |
Cancer Cell |
| Title: |
A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. |
| Volume: |
24 |
| Issue: |
1 |
| Pages: |
59-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hahn KL |
| Year: |
2009 |
| Journal: |
Reproduction |
| Title: |
A deficiency of lunatic fringe is associated with cystic dilation of the rete testis. |
| Volume: |
137 |
| Issue: |
1 |
| Pages: |
79-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meng H |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
Thrombospondin 2 potentiates notch3/jagged1 signaling. |
| Volume: |
284 |
| Issue: |
12 |
| Pages: |
7866-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pang J |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
108603 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barbarulo A |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription. |
| Volume: |
186 |
| Issue: |
11 |
| Pages: |
6199-206 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Felli MP |
| Year: |
2005 |
| Journal: |
Oncogene |
| Title: |
PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia. |
| Volume: |
24 |
| Issue: |
6 |
| Pages: |
992-1000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Checquolo S |
| Year: |
2010 |
| Journal: |
Oncogene |
| Title: |
Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia. |
| Volume: |
29 |
| Issue: |
10 |
| Pages: |
1463-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sizemore GM |
| Year: |
2017 |
| Journal: |
Oncogene |
| Title: |
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. |
| Volume: |
36 |
| Issue: |
16 |
| Pages: |
2297-2308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baron-Menguy C |
| Year: |
2017 |
| Journal: |
Hypertension |
| Title: |
Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries. |
| Volume: |
69 |
| Issue: |
1 |
| Pages: |
60-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Durrant CS |
| Year: |
2020 |
| Journal: |
Cell Death Dis |
| Title: |
Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling. |
| Volume: |
11 |
| Issue: |
2 |
| Pages: |
98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zeng H |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2?/Notch3 pathways. |
| Volume: |
6 |
|
| Pages: |
20931 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He Y |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
9770 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bellavia D |
| Year: |
2000 |
| Journal: |
EMBO J |
| Title: |
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. |
| Volume: |
19 |
| Issue: |
13 |
| Pages: |
3337-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meng H |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling. |
| Volume: |
285 |
| Issue: |
30 |
| Pages: |
23047-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindsell CE |
| Year: |
1996 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
14-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carbery ID |
| Year: |
2010 |
| Journal: |
Genetics |
| Title: |
Targeted genome modification in mice using zinc-finger nucleases. |
| Volume: |
186 |
| Issue: |
2 |
| Pages: |
451-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu YR |
| Year: |
2013 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension. |
| Volume: |
48 |
| Issue: |
5 |
| Pages: |
647-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2018 |
| Journal: |
Cardiovasc Res |
| Title: |
Cbx3 inhibits vascular smooth muscle cell proliferation, migration, and neointima formation. |
| Volume: |
114 |
| Issue: |
3 |
| Pages: |
443-455 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
5100
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4660
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3567
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
5634
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1403
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1245
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
862
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
704
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
873
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1319
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
931
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
685
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
689
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4545
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
739
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
996
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4599
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
818
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4545
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
955
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
862
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
862
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
862
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
862
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
810
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
724
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
810
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4599
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
896
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
818
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
773
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1403
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
931
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
724
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1294
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1403
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
845
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
722
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
722
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2098
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
828
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
787
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
726
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
832
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
694
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3357
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
870
 |
| Fragment?: |
false |
|
•
•
•
•
•
|