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Search results 5601 to 5700 out of 7122 for App

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Type Details Score
Publication
First Author: Pawlikowski B
Year: 2018
Journal: Sci Rep
Title: Muscle stem cell dysfunction impairs muscle regeneration in a mouse model of Down syndrome.
Volume: 8
Issue: 1
Pages: 4309
Publication  
First Author: Bianchi P
Year: 2014
Journal: Exp Neurol
Title: Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome.
Volume: 251
Pages: 1-11
Publication  
First Author: Vidal V
Year: 2012
Journal: Neuroscience
Title: Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome.
Volume: 220
Pages: 158-68
Publication  
First Author: Das D
Year: 2015
Journal: Neurosci Lett
Title: Increased incidence of intermittent hypoxemia in the Ts65Dn mouse model of Down syndrome.
Volume: 604
Pages: 91-6
Publication
First Author: Lauterborn JC
Year: 2019
Journal: Transl Psychiatry
Title: Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities.
Volume: 9
Issue: 1
Pages: 166
Publication
First Author: Rueda N
Year: 2005
Journal: Neurosci Lett
Title: Cell proliferation is reduced in the dentate gyrus of aged but not young Ts65Dn mice, a model of Down syndrome.
Volume: 380
Issue: 1-2
Pages: 197-201
Publication  
First Author: Bao J
Year: 2022
Journal: Front Cell Neurosci
Title: Detecting Cochlear Synaptopathy Through Curvature Quantification of the Auditory Brainstem Response.
Volume: 16
Pages: 851500
Publication
First Author: Berg BM
Year: 2000
Journal: Growth Dev Aging
Title: Peptide YY administration decreases brain aluminum in the Ts65Dn Down syndrome mouse model.
Volume: 64
Issue: 1-2
Pages: 3-19
Publication  
First Author: Helm S
Year: 2017
Journal: Front Cell Neurosci
Title: Deleterious Effects of Chronic Folate Deficiency in the Ts65Dn Mouse Model of Down Syndrome.
Volume: 11
Pages: 161
Publication
First Author: Paz-Miguel JE
Year: 1999
Journal: J Immunol
Title: Reactive oxygen intermediates during programmed cell death induced in the thymus of the Ts(1716)65Dn mouse, a murine model for human Down's syndrome.
Volume: 163
Issue: 10
Pages: 5399-410
Publication  
First Author: Thomazeau A
Year: 2023
Journal: Front Neurosci
Title: Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome.
Volume: 17
Pages: 1171797
Publication  
First Author: Vacano GN
Year: 2018
Journal: Neurobiol Aging
Title: Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model.
Volume: 63
Pages: 96-109
Publication
First Author: Huang W
Year: 2000
Journal: Neuroreport
Title: Brain myo-inositol level is elevated in Ts65Dn mouse and reduced after lithium treatment.
Volume: 11
Issue: 3
Pages: 445-8
Publication
First Author: Sebastiani G
Year: 2006
Journal: Hum Mol Genet
Title: Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.
Volume: 15
Issue: 15
Pages: 2313-23
Publication  
First Author: McKeever PM
Year: 2017
Journal: Neurobiol Aging
Title: Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer's disease.
Volume: 57
Pages: 104-119
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: transgenic, congenic
Strain
Attribute String: congenic, transgenic
Strain
Attribute String: mutant stock, targeted mutation
Publication
First Author: Dewachter I
Year: 2009
Journal: Neurobiol Aging
Title: Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice.
Volume: 30
Issue: 2
Pages: 241-56
Publication
First Author: Wyss-Coray T
Year: 1997
Journal: Nature
Title: Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease.
Volume: 389
Issue: 6651
Pages: 603-6
Publication
First Author: Chong SA
Year: 2011
Journal: Neurobiol Dis
Title: Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: a multi-electrode array study.
Volume: 44
Issue: 3
Pages: 284-91
Publication  
First Author: Samaey C
Year: 2019
Journal: Front Aging Neurosci
Title: Early Cognitive and Behavioral Deficits in Mouse Models for Tauopathy and Alzheimer's Disease.
Volume: 11
Pages: 335
Strain
Attribute String: transgenic, mutant strain, coisogenic
Publication  
First Author: Oliveira-Souza FG
Year: 2017
Journal: Neuroscience
Title: Retinal changes in the Tg-SwDI mouse model of Alzheimer's disease.
Volume: 354
Pages: 43-53
Publication  
First Author: Rosas-Hernandez H
Year: 2020
Journal: Neuroscience
Title: Impaired Amyloid Beta Clearance and Brain Microvascular Dysfunction are Present in the Tg-SwDI Mouse Model of Alzheimer's Disease.
Volume: 440
Pages: 48-55
Publication
First Author: Choi S
Year: 2020
Journal: FASEB J
Title: Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathology.
Volume: 34
Issue: 5
Pages: 6808-6823
Publication  
First Author: Daschil N
Year: 2016
Journal: Front Aging Neurosci
Title: Green-Fluorescent Protein(+) Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis.
Volume: 8
Pages: 75
Publication  
First Author: Moelgg K
Year: 2021
Journal: Biomolecules
Title: Spreading of Beta-Amyloid in Organotypic Mouse Brain Slices and Microglial Elimination and Effects on Cholinergic Neurons.
Volume: 11
Issue: 3
Publication  
First Author: Roberts AM
Year: 2016
Journal: Physiol Rep
Title: Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease.
Volume: 4
Issue: 17
Publication
First Author: Xu F
Year: 2007
Journal: Neuroscience
Title: Early-onset subicular microvascular amyloid and neuroinflammation correlate with behavioral deficits in vasculotropic mutant amyloid beta-protein precursor transgenic mice.
Volume: 146
Issue: 1
Pages: 98-107
Publication    
First Author: Munting LP
Year: 2021
Journal: Elife
Title: Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis.
Volume: 10
Publication  
First Author: Rodriguez-Lopez A
Year: 2023
Journal: J Neuroimmunol
Title: Increased TSPO expression, pyroglutamate-modified amyloid beta (AβN3(pE)) accumulation and transient clustering of microglia in the thalamus of Tg-SwDI mice.
Volume: 382
Pages: 578150
Publication  
First Author: Foidl BM
Year: 2018
Journal: Front Aging Neurosci
Title: Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid.
Volume: 10
Pages: 113
Publication  
First Author: Foidl BM
Year: 2019
Journal: Brain Behav Immun
Title: Chronic treatment with five vascular risk factors causes cerebral amyloid angiopathy but no Alzheimer pathology in C57BL6 mice.
Volume: 78
Pages: 52-64
Publication  
First Author: Fan R
Year: 2007
Journal: J Neuroinflammation
Title: Induction of complement proteins in a mouse model for cerebral microvascular A beta deposition.
Volume: 4
Pages: 22
Publication  
First Author: Paul JR
Year: 2018
Journal: Neurobiol Dis
Title: Behavioral and SCN neurophysiological disruption in the Tg-SwDI mouse model of Alzheimer's disease.
Volume: 114
Pages: 194-200
Publication
First Author: Dhurandhar EJ
Year: 2013
Journal: PLoS One
Title: Hunger in the absence of caloric restriction improves cognition and attenuates Alzheimer's disease pathology in a mouse model.
Volume: 8
Issue: 4
Pages: e60437
Publication
First Author: Zhang L
Year: 2013
Journal: Biochim Biophys Acta
Title: Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice.
Volume: 1832
Issue: 9
Pages: 1456-62
Publication
First Author: Hutter-Schmid B
Year: 2016
Journal: Pharmacology
Title: Alpha-Smooth Muscle Actin mRNA and Protein Are Increased in Isolated Brain Vessel Extracts of Alzheimer Mice.
Volume: 98
Issue: 5-6
Pages: 251-260
Publication  
First Author: Humpel C
Year: 2021
Journal: Front Aging Neurosci
Title: Intranasal Delivery of Collagen-Loaded Neprilysin Clears Beta-Amyloid Plaques in a Transgenic Alzheimer Mouse Model.
Volume: 13
Pages: 649646
Publication
First Author: Zhong R
Year: 2024
Journal: Alzheimers Dement
Title: Loss of TREM2 diminishes CAA despite an overall increase of amyloid load in Tg-SwDI mice.
Volume: 20
Issue: 11
Pages: 7595-7612
Publication  
First Author: Kniewallner KM
Year: 2016
Journal: Sci Rep
Title: Thiazine Red(+) platelet inclusions in Cerebral Blood Vessels are first signs in an Alzheimer's Disease mouse model.
Volume: 6
Pages: 28447
Publication
First Author: Beitnere U
Year: 2014
Journal: J Neurosci Res
Title: Mildronate improves cognition and reduces amyloid-β pathology in transgenic Alzheimer's disease mice.
Volume: 92
Issue: 3
Pages: 338-46
Publication  
First Author: Setti SE
Year: 2022
Journal: Behav Brain Res
Title: Assessment of sex-related neuropathology and cognitive deficits in the Tg-SwDI mouse model of Alzheimer's disease.
Volume: 428
Pages: 113882
Publication
First Author: Searcy JL
Year: 2014
Journal: PLoS One
Title: Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice.
Volume: 9
Issue: 2
Pages: e89970
Publication  
First Author: Situ M
Year: 2022
Journal: Front Cell Neurosci
Title: Transcriptomic Profile of Blood-Brain Barrier Remodeling in Cerebral Amyloid Angiopathy.
Volume: 16
Pages: 931247
Publication  
First Author: Platholi J
Year: 2023
Journal: Front Aging Neurosci
Title: Hippocampal glial inflammatory markers are differentially altered in a novel mouse model of perimenopausal cerebral amyloid angiopathy.
Volume: 15
Pages: 1280218
Publication  
First Author: Schemmert S
Year: 2021
Journal: Int J Mol Sci
Title: In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.
Volume: 22
Issue: 12
Publication  
First Author: Hutter-Schmid B
Year: 2018
Journal: Exp Gerontol
Title: Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b(+) microglial-like cell type in vitro.
Volume: 112
Pages: 30-37
Publication
First Author: Passos GF
Year: 2013
Journal: Am J Pathol
Title: The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice.
Volume: 182
Issue: 5
Pages: 1740-9
Publication
First Author: Kruyer A
Year: 2015
Journal: Hypertension
Title: Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease.
Volume: 66
Issue: 1
Pages: 175-82
Publication  
First Author: Choi S
Year: 2018
Journal: Neuroscience
Title: Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.
Volume: 384
Pages: 41-53
Publication  
First Author: Zhou G
Year: 2023
Journal: Int Immunopharmacol
Title: Mitochondrial calcium uptake 3 mitigates cerebral amyloid angiopathy-related neuronal death and glial inflammation by reducing mitochondrial dysfunction.
Volume: 117
Pages: 109614
Publication
First Author: Van Vickle GD
Year: 2008
Journal: Am J Pathol
Title: Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy.
Volume: 173
Issue: 2
Pages: 483-93
Publication  
First Author: Humpel C
Year: 2015
Journal: Front Aging Neurosci
Title: Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques.
Volume: 7
Pages: 47
Publication
First Author: Davis J
Year: 2006
Journal: Neurobiol Aging
Title: Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice.
Volume: 27
Issue: 7
Pages: 946-54
Publication  
First Author: Foidl BM
Year: 2016
Journal: Neurobiol Learn Mem
Title: Cholinergic neurodegeneration in an Alzheimer mouse model overexpressing amyloid-precursor protein with the Swedish-Dutch-Iowa mutations.
Volume: 136
Pages: 86-96
Publication
First Author: Meilandt WJ
Year: 2020
Journal: J Neurosci
Title: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Volume: 40
Issue: 9
Pages: 1956-1974
Strain
Attribute String: targeted mutation, mutant stock
Publication  
First Author: Rammes G
Year: 2017
Journal: Neuropharmacology
Title: Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD).
Volume: 123
Pages: 100-115
Publication
First Author: Jendresen C
Year: 2019
Journal: Sci Rep
Title: Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression.
Volume: 9
Issue: 1
Pages: 4600
Publication
First Author: Jendresen CB
Year: 2015
Journal: J Biol Chem
Title: Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
Volume: 290
Issue: 8
Pages: 5053-64
Strain
Attribute String: congenic, targeted mutation, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, endonuclease-mediated mutation, congenic
Strain
Attribute String: mutant strain, congenic, targeted mutation, endonuclease-mediated mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Tg(APP695)3Dbo/? Tg(PSEN1)S8-4Dbo/?
Background: involves: C57BL/6J * C3H/HeJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeSnJ * C57BL/6JEi * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO-APPSwInd)102Dbo/?
Background: involves: C3H/HeJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-ITM2B/APP695*40)1Emcg/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6 * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(APP)8.9Btla/Tg(APP)8.9Btla Tg(SOD1)51Yg/Tg(SOD1)51Yg
Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(APP)8.9Btla/Tg(APP)8.9Btla Tg(SOD1)69Yg/Tg(SOD1)69Yg
Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Gfap-TGFB1)64Lms/? Tg(PDGFB-APPInd)H6Lms/?
Background: involves: BALB/c * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(APPV717I)1130Kha/? Tg(Pgk1-FGF2)15Cofn/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: App/App
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H * C57BL/6 * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6JEi * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: B6EiC3Sn a/A-Ts(17<16>)65Dn/J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Rcan1/Rcan1<+> Ts(17<16>)65Dn/?
Background: involves: 129S4/SvJae * C3H/HeSn * C57BL/6 * C57BL/6Ei * DBA/2J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: B6EiC3Sn.BLiA-Ts(17<16>)65Dn/DnJ
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Del(16App-Runx1)5Yah/? Ts(17<16>)65Dn/?
Background: involves: BALB/c * C3H * C57BL/6 * DBA/2J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeH * C3H/HeSn * C57BL/6Ei * C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Npc1/Npc1 Tg(PRNP-APPSweInd)8Dwst/?
Background: involves: BALB/c * C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(APPV717F)109Ili/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Omp/Omp<+> Tg(tetO-APPSwInd)Dbo/?
Background: involves: 129 * C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Gng8-tTA)#Ryba/? Tg(tetO-APPSwInd)Dbo/?
Background: involves: 129 * C3H/HeJ * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Or8a1/Or8a1<+> Omp/Omp<+> Tg(tetO-APPSwInd)Dbo/?
Background: involves: 129 * C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Becn1/Becn1 Tg(APPV717F)109Ili/?
Background: B6.Cg-Becn1 Tg(APPV717F)109Ili
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2/Bcl2 Tg(APPV717F)109Ili/?
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(APPSWE)2576Kha/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: BALB/c * C3H/He * C57BL/6JEiJ * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Sinha S
Year: 1999
Journal: Nature
Title: Purification and cloning of amyloid precursor protein beta-secretase from human brain.
Volume: 402
Issue: 6761
Pages: 537-40