Type |
Details |
Score |
Publication |
First Author: |
Klucky B |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion. |
Volume: |
67 |
Issue: |
17 |
Pages: |
8198-206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2. |
Volume: |
284 |
Issue: |
6 |
Pages: |
3691-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhardt S |
Year: |
2007 |
Journal: |
J Mol Biol |
Title: |
Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains. |
Volume: |
373 |
Issue: |
4 |
Pages: |
891-902 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang J |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Ectodomain shedding and autocleavage of the cardiac membrane protease corin. |
Volume: |
286 |
Issue: |
12 |
Pages: |
10066-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cisse M |
Year: |
2011 |
Journal: |
Mol Cell Neurosci |
Title: |
ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε. |
Volume: |
47 |
Issue: |
3 |
Pages: |
223-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2013 |
Journal: |
Biochim Biophys Acta |
Title: |
ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils. |
Volume: |
1833 |
Issue: |
3 |
Pages: |
680-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garbers C |
Year: |
2014 |
Journal: |
Biochim Biophys Acta |
Title: |
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases. |
Volume: |
1842 |
Issue: |
9 |
Pages: |
1485-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Londino JD |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling. |
Volume: |
290 |
Issue: |
52 |
Pages: |
31113-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parra LM |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44. |
Volume: |
35 |
Issue: |
19 |
Pages: |
3381-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen AC |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. |
Volume: |
211 |
Issue: |
6 |
Pages: |
1157-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Braley A |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function. |
Volume: |
291 |
Issue: |
23 |
Pages: |
12057-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang XL |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Overexpression of MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10. |
Volume: |
482 |
Issue: |
4 |
Pages: |
928-934 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varbanov H |
Year: |
2017 |
Journal: |
Mol Cell Neurosci |
Title: |
Regulation of extrasynaptic signaling by polysialylated NCAM: Impact for synaptic plasticity and cognitive functions. |
Volume: |
81 |
|
Pages: |
12-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mehta V |
Year: |
2018 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1 Fragments That Regulate Angiogenic Signaling. |
Volume: |
38 |
Issue: |
8 |
Pages: |
1845-1858 |
|
•
•
•
•
•
|
Publication |
First Author: |
Steuble M |
Year: |
2012 |
Journal: |
Biol Open |
Title: |
Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport. |
Volume: |
1 |
Issue: |
8 |
Pages: |
761-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson RL |
Year: |
2021 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth. |
Volume: |
320 |
Issue: |
5 |
Pages: |
R653-R662 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni XQ |
Year: |
2021 |
Journal: |
Aging (Albany NY) |
Title: |
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway. |
Volume: |
13 |
Issue: |
4 |
Pages: |
5164-5184 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews LP |
Year: |
2020 |
Journal: |
Sci Immunol |
Title: |
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. |
Volume: |
5 |
Issue: |
49 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Balic JJ |
Year: |
2017 |
Journal: |
Cytokine |
Title: |
Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling. |
Volume: |
92 |
|
Pages: |
118-123 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida F |
Year: |
2024 |
Journal: |
Transl Psychiatry |
Title: |
Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons. |
Volume: |
14 |
Issue: |
1 |
Pages: |
448 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
502
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
381
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Eto K |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions. |
Volume: |
277 |
Issue: |
20 |
Pages: |
17804-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herr UM |
Year: |
2017 |
Journal: |
Front Mol Neurosci |
Title: |
LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State. |
Volume: |
10 |
|
Pages: |
118 |
|
•
•
•
•
•
|
Publication |
First Author: |
Willem M |
Year: |
2015 |
Journal: |
Nature |
Title: |
η-Secretase processing of APP inhibits neuronal activity in the hippocampus. |
Volume: |
526 |
Issue: |
7573 |
Pages: |
443-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao K |
Year: |
2019 |
Journal: |
Alzheimers Res Ther |
Title: |
Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. |
Volume: |
11 |
Issue: |
1 |
Pages: |
35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gossens K |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. |
Volume: |
5 |
Issue: |
9 |
Pages: |
e12766 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyoshi A |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
JNK and ATF4 as two important platforms for tumor necrosis factor-α-stimulated shedding of receptor for advanced glycation end products. |
Volume: |
33 |
Issue: |
3 |
Pages: |
3575-3589 |
|
•
•
•
•
•
|
Publication |
First Author: |
Metz VV |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Induction of RAGE shedding by activation of G protein-coupled receptors. |
Volume: |
7 |
Issue: |
7 |
Pages: |
e41823 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broder C |
Year: |
2013 |
Journal: |
Biochem J |
Title: |
The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis. |
Volume: |
450 |
Issue: |
2 |
Pages: |
253-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones JC |
Year: |
2019 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. |
Volume: |
7 |
Issue: |
3 |
Pages: |
533-554 |
|
•
•
•
•
•
|
Publication |
First Author: |
Couchie D |
Year: |
2017 |
Journal: |
Circulation |
Title: |
Human Plasma Thioredoxin-80 Increases With Age and in ApoE-/- Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. |
Volume: |
136 |
Issue: |
5 |
Pages: |
464-475 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ri A |
Year: |
2018 |
Journal: |
Front Cell Dev Biol |
Title: |
Progression of Pulmonary Emphysema and Continued Increase in Ectodomain Shedding of Cell Adhesion Molecule 1 After Cessation of Cigarette Smoke Exposure in Mice. |
Volume: |
6 |
|
Pages: |
52 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
749
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
513
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
215
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
215
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
215
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
318
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
215
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
704
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
747
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
760
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
846
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
395
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
846
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|