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Search results 601 to 641 out of 641 for Arid1a

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Type

Details

Score

HT Experiment

GSE163273 | Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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Publication

37292940 | J:356369

First Author:	Menon DU
Year:	2024
Journal:	bioRxiv
Title:	ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse.

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HT Experiment

GSE169562 | ChIP-seq and RNA-seq profiling of mice hippocampus before and after Arid1a conditional knockout.


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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Publication

42230634 | J:390368

First Author:	Liu H
Year:	2026
Journal:	Nat Commun
Title:	ARID1A loss drives gastric signet ring cell carcinoma by regulating mucin production and secretion.
Volume:	17
Issue:	1

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HT Experiment

GSE221176 | Endothelial Arid1a Deletion Disrupts the Balance among Angiogenesis, Neurogenesis, and Astrogenesis in the Developing Brain


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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HT Experiment

GSE225610 | ARID1A governs silencing of sex-linked transcription during male meiosis in the mouse [RNA-seq]


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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Publication

36435834 | J:331706

First Author:	Li N
Year:	2022
Journal:	Nat Commun
Title:	ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression.
Volume:	13
Issue:	1
Pages:	7281

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HT Experiment

GSE166333 | Transcriptome analysis of murine primary pancreatic acinar cells in the context of Arid1a deficiency


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

•

HT Experiment

GSE124694 | Arid1a loss drives non-alcoholic steatohepatitis in mice via epigenetic dysregulation of hepatic lipogenesis and fatty acid oxidation


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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DO Term

DOID:0070044 | Coffin-Siris syndrome 2

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HT Experiment

GSE198916 | Next-generation sequencing Facilitates Quantitative Analysis of Wild Type and Arid1a haploinsufficiency mice excitatory neuron Transcriptomes and Genome-wide maps of chromatin state in Wild Type and Ar id1a Haploinsufficiency mice in excitatory neuron


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

•

HT Experiment

GSE126645 | Antagonistic interaction between Ezh2 and Arid1a coordinates dental root patterning via Cdkn2a [RNA-Seq]


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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Allele

Arid1a<em1Smoc> | MGI:7288340

Name:	AT-rich interaction domain 1A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

•

Allele

Arid1a<tm1Yzhao> | MGI:6864454

Name:	AT-rich interaction domain 1A; targeted mutation 1, Yong Zhao
Allele Type:	Targeted
Attribute String:	Conditional ready, Epitope tag, Reporter

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Strain

MGI:7623301 | C57BL/6JSmoc-Arid1a<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7751731 | C57BL/6JSmoc-Arid1a<em1Smoc> Pten<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

HT Experiment

E-GEOD-32116 | ARID-DNA interactions are essential for SWI/SNF function

Series Id:	GSE32116
Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

HT Experiment

GSE325094 | Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

•

Publication

12665591 | -

First Author:	Nie Z
Year:	2003
Journal:	Mol Cell Biol
Title:	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.
Volume:	23
Issue:	8
Pages:	2942-52

•

Publication

22405089 | -

First Author:	Hoyer J
Year:	2012
Journal:	Am J Hum Genet
Title:	Haploinsufficiency of ARID1B, a member of the SWI/SNF-a chromatin-remodeling complex, is a frequent cause of intellectual disability.
Volume:	90
Issue:	3
Pages:	565-72

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Publication

23660946 | -

First Author:	Khursheed M
Year:	2013
Journal:	Br J Cancer
Title:	ARID1B, a member of the human SWI/SNF chromatin remodeling complex, exhibits tumour-suppressor activities in pancreatic cancer cell lines.
Volume:	108
Issue:	10
Pages:	2056-62

•

Publication

22426309 | -

First Author:	Santen GW
Year:	2012
Journal:	Nat Genet
Title:	Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome.
Volume:	44
Issue:	4
Pages:	379-80

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Publication

24562383 | -

First Author:	Helming KC
Year:	2014
Journal:	Nat Med
Title:	ARID1B is a specific vulnerability in ARID1A-mutant cancers.
Volume:	20
Issue:	3
Pages:	251-4

•

Protein Domain

IPR038040 | ARID_ARID1B

Type:

Domain

Description:

AT-rich interactive domain-containing protein 1B (ARID1B or BAF250b) is part of the SWI/SNF-like ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling [, ]. In humans there are two BAF250 isoforms, BAF250a/ARID1A and BAF250b/ARID1B []. Both BAF250a and BAF250b bind DNA non-specifically []. BAF250b is also a component of the BAF [], SWI/SNF-like EBAFb [], npBAF and nBAF complexes [], which remodel chromatin. ARID1B exhibits tumour-suppressor activities in pancreatic cancer cell lines [, [cite:]]. Mutations in the ARID1B gene cause Coffin-Siris syndrome, exhibiting developmental defects, and haplo-insufficiency of ARID1B, a frequent cause of intellectual disability [, ]. Moreover, mutations in the ARID1B gene have been found in many cancers [].This entry represents the ARID/BRIGHT DNA binding domain of ARI1B. It binds DNA in a non-sequence-specific manner similar to ARID1A [].

•

Publication

15170388 | -

First Author:	Wang X
Year:	2004
Journal:	Biochem J
Title:	Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.
Volume:	383
Issue:	Pt 2
Pages:	319-25

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Publication

14982958 | -

First Author:	Wilsker D
Year:	2004
Journal:	Nucleic Acids Res
Title:	The DNA-binding properties of the ARID-containing subunits of yeast and mammalian SWI/SNF complexes.
Volume:	32
Issue:	4
Pages:	1345-53

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Publication

25686104 | J:227937

First Author:	Bitler BG
Year:	2015
Journal:	Nat Med
Title:	Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers.
Volume:	21
Issue:	3
Pages:	231-8

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Publication

28758902 | J:247849

First Author:	Enane FO
Year:	2017
Journal:	J Clin Invest
Title:	GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition.
Volume:	127
Issue:	9
Pages:	3527-3542

•

Publication

39226899 | J:355471

First Author:	Barnada SM
Year:	2024
Journal:	Am J Hum Genet
Title:	ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification.
Volume:	111
Issue:	10
Pages:	2232-2252

•

Publication

27838634 | J:237986

First Author:	Rao CV
Year:	2017
Journal:	Carcinogenesis
Title:	Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.
Volume:	38
Issue:	1
Pages:	2-11

•

Publication

38415925 | J:345790

First Author:	Alexander WB
Year:	2024
Journal:	Dis Model Mech
Title:	Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.
Volume:	17
Issue:	6

•

Publication

26601204 | -

First Author:	Kadoch C
Year:	2015
Journal:	Sci Adv
Title:	Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.
Volume:	1
Issue:	5
Pages:	e1500447

•

Publication

18765789 | J:138780

First Author:	Lange M
Year:	2008
Journal:	Genes Dev
Title:	Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Volume:	22
Issue:	17
Pages:	2370-84

•

Publication

22952240 | -

First Author:	Euskirchen G
Year:	2012
Journal:	J Biol Chem
Title:	SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.
Volume:	287
Issue:	37
Pages:	30897-905

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Publication

11867548 | -

First Author:	Iwahara J
Year:	2002
Journal:	EMBO J
Title:	The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.
Volume:	21
Issue:	5
Pages:	1197-209

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Publication

31886851 | J:342311

First Author:	Wilson MR
Year:	2020
Journal:	Hum Reprod
Title:	A mouse model of endometriosis mimicking the natural spread of invasive endometrium.
Volume:	35
Issue:	1
Pages:	58-69

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Protein

E9Q4N7

Organism:	Mus musculus/domesticus
Length:	2306
Fragment?:	false

•

Protein

E9Q6R4

Organism:	Mus musculus/domesticus
Length:	2243
Fragment?:	false

•

Protein

A0A338P6U8

Organism:	Mus musculus/domesticus
Length:	2296
Fragment?:	false

•

Protein

A0A8Q0PK87

Organism:	Mus musculus/domesticus
Length:	2244
Fragment?:	false

•

Protein

E9Q4N6

Organism:	Mus musculus/domesticus
Length:	1762
Fragment?:	false

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