|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 700 out of 8285 for C2

0.056s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Davletov BA
Year: 1993
Journal: J Biol Chem
Title: A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
Volume: 268
Issue: 35
Pages: 26386-90
Publication
First Author: Hadjighassem MR
Year: 2011
Journal: Eur J Neurosci
Title: Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene.
Volume: 33
Issue: 2
Pages: 214-23
Protein
Organism: Mus musculus/domesticus
Length: 2282  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
Publication
First Author: Chih B
Year: 2011
Journal: Nat Cell Biol
Title: A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Volume: 14
Issue: 1
Pages: 61-72
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Stepan J
Year: 2022
Journal: Cell Rep
Title: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning.
Volume: 41
Issue: 10
Pages: 111766
Publication
First Author: Morris NJ
Year: 1999
Journal: Biochim Biophys Acta
Title: Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains.
Volume: 1431
Issue: 2
Pages: 525-30
Publication
First Author: Fukuda M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.
Volume: 281
Issue: 5
Pages: 1226-33
Publication
First Author: Ye H
Year: 2013
Journal: Biochim Biophys Acta
Title: NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine.
Volume: 1828
Issue: 3
Pages: 1083-93
Publication
First Author: Parekh R
Year: 1996
Journal: J Biol Chem
Title: Inhibition of myogenesis in mouse C2 cells by double-stranded phosphorothioate oligodeoxynucleotides containing mef-1 sequence.
Volume: 271
Issue: 29
Pages: 17372-6
Publication
First Author: Brown RA
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Identification and cDNA cloning of a novel mammalian C2 domain-containing phosphoinositide 3-kinase, HsC2-PI3K.
Volume: 233
Issue: 2
Pages: 537-44
Publication
First Author: Saha S
Year: 2016
Journal: FEBS Lett
Title: N-terminal polar amino acids of the C2 insert of nonmuscle myosin II-C2 regulate its functional properties.
Volume: 590
Issue: 23
Pages: 4223-4232
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Miyazaki K
Year: 2004
Journal: J Biol Chem
Title: NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.
Volume: 279
Issue: 12
Pages: 11327-35
MP Term
Protein
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
Publication
First Author: Rogaeva A
Year: 2007
Journal: J Biol Chem
Title: Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene.
Volume: 282
Issue: 29
Pages: 20897-905
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Shin OH
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release.
Volume: 106
Issue: 38
Pages: 16469-74
Publication
First Author: Yagi H
Year: 2015
Journal: J Biol Chem
Title: Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
Volume: 290
Issue: 42
Pages: 25213-26
Publication  
First Author: Lazaro JB
Year: 1997
Journal: J Cell Sci
Title: Cyclin dependent kinase 5, cdk5, is a positive regulator of myogenesis in mouse C2 cells.
Volume: 110 ( Pt 10)
Pages: 1251-60
Publication
First Author: Kobayashi M
Year: 1998
Journal: Exp Cell Res
Title: Stable expression of antisense Rb-1 RNA inhibits terminal differentiation of mouse myoblast C2 cells.
Volume: 239
Issue: 1
Pages: 40-9
Publication  
First Author: Fu X
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Staphylococcal enterotoxin C2 mutant drives T lymphocyte activation through PI3K/mTOR and NF-ĸB signaling pathways.
Volume: 333
Pages: 51-59
Protein
Organism: Mus musculus/domesticus
Length: 1061  
Fragment?: false
Publication
First Author: Kouchi Z
Year: 2005
Journal: J Biol Chem
Title: The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase Czeta.
Volume: 280
Issue: 22
Pages: 21015-21
Publication  
First Author: Rasmussen CLM
Year: 2023
Journal: Mol Cell Neurosci
Title: The Npc2(Gt(LST105)BygNya) mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease.
Volume: 126
Pages: 103880
Publication  
First Author: Liao YJ
Year: 2012
Journal: Mol Med
Title: Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.
Volume: 18
Pages: 412-22
Publication
First Author: Gangadharan B
Year: 2017
Journal: Haematologica
Title: The C1 and C2 domains of blood coagulation factor VIII mediate its endocytosis by dendritic cells.
Volume: 102
Issue: 2
Pages: 271-281
Publication
First Author: Al-Tawashi A
Year: 2012
Journal: J Biol Chem
Title: Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity.
Volume: 287
Issue: 18
Pages: 14644-58
Publication
First Author: Nalefski EA
Year: 1996
Journal: Protein Sci
Title: The C2 domain calcium-binding motif: structural and functional diversity.
Volume: 5
Issue: 12
Pages: 2375-90
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1276  
Fragment?: false
Publication
First Author: Liu L
Year: 2006
Journal: J Biol Chem
Title: Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha.
Volume: 281
Issue: 7
Pages: 4254-60
Publication
First Author: Shao X
Year: 1996
Journal: Science
Title: Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C.
Volume: 273
Issue: 5272
Pages: 248-51
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: multiple C2 domains, transmembrane 1; deaf wanderer
Allele Type: Spontaneous
Attribute String: Modified regulatory region, Null/knockout
Publication
First Author: Tsang WY
Year: 2009
Journal: Dev Cell
Title: Cep76, a centrosomal protein that specifically restrains centriole reduplication.
Volume: 16
Issue: 5
Pages: 649-60
Protein Domain
Type: Domain
Description: A C2 domain is usually involved in targeting proteins to cell membranes. This entry represents a C2 domain found in the CEP76 proteins []. CEP76 is a centrosomal protein involved in regulation of centriole duplication [].
Protein
Organism: Mus musculus/domesticus
Length: 1082  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 903  
Fragment?: false
GXD Expression
Probe: MGI:5435869
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5436321
Age: embryonic day 12.5
Image: 2C
Note: Expression is present in the c2 domain.
Specimen Label: 2C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5435869
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5436321
Age: embryonic day 12.5
Image: 5A
Note: Expression is present in the c2 domain.
Specimen Label: 5A
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5435869
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5436321
Age: embryonic day 12.5
Image: 5B
Note: Expression is present in the c2 domain.
Specimen Label: 5B
Detected: true
Specimen Num: 3
Protein
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
Allele
Name: glucosaminyl (N-acetyl) transferase 1, core 2; targeted mutation 2, Jamey Marth
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Publication
First Author: Fukuda M
Year: 2002
Journal: J Biol Chem
Title: Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin.
Volume: 277
Issue: 45
Pages: 43096-103
Publication
First Author: Liao YJ
Year: 2015
Journal: Int J Cancer
Title: Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications.
Volume: 137
Issue: 6
Pages: 1341-51
Publication
First Author: Schrantz N
Year: 2007
Journal: J Exp Med
Title: The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells.
Volume: 204
Issue: 4
Pages: 841-52
Publication  
First Author: Markmann S
Year: 2018
Journal: Exp Neurol
Title: Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
Volume: 306
Pages: 22-33
Publication
First Author: Chazot PL
Year: 1997
Journal: J Neurochem
Title: Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor.
Volume: 68
Issue: 2
Pages: 507-16
UniProt Feature
Begin: 1
Description: Doublesex- and mab-3-related transcription factor C2
Type: chain
End: 370
UniProt Feature
Begin: 1
Description: Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
Type: chain
End: 1506
UniProt Feature
Begin: 1
Description: Multiple C2 and transmembrane domain-containing protein 1
Type: chain
End: 951
UniProt Feature
Begin: 1
Description: Multiple C2 and transmembrane domain-containing protein 2
Type: chain
End: 878