Type |
Details |
Score |
Publication |
First Author: |
Pennica D |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. |
Volume: |
95 |
Issue: |
25 |
Pages: |
14717-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shao H |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis. |
Volume: |
7 |
Issue: |
48 |
Pages: |
79262-79273 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lukjanenko L |
Year: |
2019 |
Journal: |
Cell Stem Cell |
Title: |
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors. |
Volume: |
24 |
Issue: |
3 |
Pages: |
433-446.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams H |
Year: |
2016 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Wnt2 and WISP-1/CCN4 Induce Intimal Thickening via Promotion of Smooth Muscle Cell Migration. |
Volume: |
36 |
Issue: |
7 |
Pages: |
1417-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung TW |
Year: |
2018 |
Journal: |
J Cell Physiol |
Title: |
WISP1 promotes non-alcoholic fatty liver disease and skeletal muscle insulin resistance via TLR4/JNK signaling. |
Volume: |
233 |
Issue: |
8 |
Pages: |
6077-6087 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono M |
Year: |
2011 |
Journal: |
J Bone Miner Res |
Title: |
WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. |
Volume: |
26 |
Issue: |
1 |
Pages: |
193-208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sleeman MA |
Year: |
2000 |
Journal: |
Genomics |
Title: |
Gene expression in rat dermal papilla cells: analysis of 2529 ESTs. |
Volume: |
69 |
Issue: |
2 |
Pages: |
214-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang X |
Year: |
2020 |
Journal: |
J Cell Physiol |
Title: |
WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy. |
Volume: |
235 |
Issue: |
3 |
Pages: |
2009-2022 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Z |
Year: |
2024 |
Journal: |
Cells |
Title: |
WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts' Activation and Collagen Processing. |
Volume: |
13 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ferrand N |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
WISP1/CCN4 inhibits adipocyte differentiation through repression of PPARγ activity. |
Volume: |
7 |
Issue: |
1 |
Pages: |
1749 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto Y |
Year: |
1996 |
Journal: |
Cancer Res |
Title: |
Identification of genes differentially expressed in association with metastatic potential of K-1735 murine melanoma by messenger RNA differential display. |
Volume: |
56 |
Issue: |
22 |
Pages: |
5266-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawaki H |
Year: |
2008 |
Journal: |
J Bone Miner Res |
Title: |
Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. |
Volume: |
23 |
Issue: |
11 |
Pages: |
1751-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Geng R |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea. |
Volume: |
11 |
Issue: |
2 |
Pages: |
e0148339 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori AD |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. |
Volume: |
297 |
Issue: |
2 |
Pages: |
566-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nunes AM |
Year: |
2017 |
Journal: |
Hum Mol Genet |
Title: |
Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. |
Volume: |
26 |
Issue: |
11 |
Pages: |
2018-2033 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa N |
Year: |
2015 |
Journal: |
Kidney Int |
Title: |
Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis. |
Volume: |
87 |
Issue: |
6 |
Pages: |
1125-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saravanamuthu SS |
Year: |
2012 |
Journal: |
Dev Biol |
Title: |
Conditional ablation of the Notch2 receptor in the ocular lens. |
Volume: |
362 |
Issue: |
2 |
Pages: |
219-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Witte F |
Year: |
2009 |
Journal: |
Gene Expr Patterns |
Title: |
Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. |
Volume: |
9 |
Issue: |
4 |
Pages: |
215-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lun MP |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. |
Volume: |
35 |
Issue: |
12 |
Pages: |
4903-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida S |
Year: |
2004 |
Journal: |
Hum Mol Genet |
Title: |
Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. |
Volume: |
13 |
Issue: |
14 |
Pages: |
1487-503 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dasgupta K |
Year: |
2019 |
Journal: |
Dev Biol |
Title: |
Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling. |
Volume: |
455 |
Issue: |
2 |
Pages: |
434-448 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HT |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. |
Volume: |
116 |
Issue: |
51 |
Pages: |
25697-25706 |
|
•
•
•
•
•
|
Publication |
First Author: |
Du J |
Year: |
2010 |
Journal: |
Dev Biol |
Title: |
O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. |
Volume: |
346 |
Issue: |
1 |
Pages: |
25-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ye Q |
Year: |
2022 |
Journal: |
Development |
Title: |
Understanding the development of oral epithelial organs through single cell transcriptomic analysis. |
Volume: |
149 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Martinez G |
Year: |
2009 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. |
Volume: |
50 |
Issue: |
10 |
Pages: |
4794-806 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perera SN |
Year: |
2020 |
Journal: |
Glia |
Title: |
Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. |
Volume: |
68 |
Issue: |
12 |
Pages: |
2550-2584 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Abonnenc M |
Year: |
2013 |
Journal: |
Circ Res |
Title: |
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. |
Volume: |
113 |
Issue: |
10 |
Pages: |
1138-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
European Mouse Mutant Archive |
Year: |
2003 |
Journal: |
Unpublished |
Title: |
Information obtained from the European Mouse Mutant Archive (EMMA) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
cellular communication network factor 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
cellular communication network factor 4; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen CC |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. |
Volume: |
276 |
Issue: |
50 |
Pages: |
47329-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Su F |
Year: |
2002 |
Journal: |
Genes Dev |
Title: |
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. |
Volume: |
16 |
Issue: |
1 |
Pages: |
46-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin CG |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family. |
Volume: |
278 |
Issue: |
26 |
Pages: |
24200-8 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of IGFBP (insulin-like growth fac-tor (IGF) binding proteins)-related proteins, which have been annotated as the CNN family [, ]. Members of the CCN family are composed of an N-terminal secretory signal peptide followed by four conserved domains with homology to insulin-like growth factor binding protein, von Willebrand factor type C repeat, thrombospondin type 1 repeat, and a C-terminal domain (CT) with heparin-binding motifs and sequence similarity to the C termini of von Willebrand factor and mucin. The CCN family includes CCN1 (CYR61) [], CCN2 (CTGF), CCN3 [], CCN4 (WISP-1) [], CCN5 (WISP-2), and CCN6 (WISP-3). |
|
•
•
•
•
•
|
Publication |
First Author: |
Baxter RC |
Year: |
1998 |
Journal: |
J Clin Endocrinol Metab |
Title: |
Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily. |
Volume: |
83 |
Issue: |
9 |
Pages: |
3213 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
348
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
367
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
379
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
367
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
379
 |
Fragment?: |
false |
|
•
•
•
•
•
|