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Search results 601 to 700 out of 929 for Ccr7

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Type Details Score
Protein Domain
IPR001718 | Chemokine_CCR7
Type: Family
Description: Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).CC chemokine receptors are a subfamily of the chemokine receptors that specifically bind and respond to cytokines of the CC chemokine family. There are currently ten members of the CC chemokine receptor subfamily, named CCR1 to 10. The receptors receptors are found in monocytes, lymphocytes, basophils and eosinophils.This entry represents CC chemokine receptor 7 (CCR7). It is expressed in various lymphoid tissues and plays an important role in the regulation of the homing and traffic of lymphocytes into and within secondary lymphoid tissues [, , , ]. It has also been shown to induce antiapoptotic signaling in mature dendritic cells []. CCR7 is seen as an important organiser of the primary immune response []. CCR7 is also expressed by various cancer cells, such as non-small lung cancer, gastric cancer and oesophageal cancer [, , ]and the expression of CCR7 by cancer cells has been linked with metastasis to lymph nodes []. CCR7 binds CCL19 and CCL21 [].
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Publication
20562329 | J:166490
First Author: Comerford I
Year: 2010
Journal: Blood
Title: The atypical chemokine receptor CCX-CKR scavenges homeostatic chemokines in circulation and tissues and suppresses Th17 responses.
Volume: 116
Issue: 20
Pages: 4130-40
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HT Experiment
GSE112270 | Expansion of tolerogenic dendritic cells in neonatal lungs programs lymph node maturation, but impairs T cell proliferation
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE224178 | Gene expression profile at single cell level of dendritic cells (DC) from the lung of neonatal (NEO) or adult (AD) mice
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
16622017 | J:131653
First Author: Ato M
Year: 2006
Journal: J Immunol
Title: Loss of dendritic cell migration and impaired resistance to Leishmania donovani infection in mice deficient in CCL19 and CCL21.
Volume: 176
Issue: 9
Pages: 5486-93
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Publication
28807994 | J:251128
First Author: Jafarnejad M
Year: 2017
Journal: J Immunol
Title: A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4.
Volume: 199
Issue: 7
Pages: 2291-2304
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Publication
16116177 | J:113244
First Author: Yopp AC
Year: 2005
Journal: J Immunol
Title: Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells.
Volume: 175
Issue: 5
Pages: 2913-24
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Publication
10706668 | -
First Author: Gosling J
Year: 2000
Journal: J Immunol
Title: Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK.
Volume: 164
Issue: 6
Pages: 2851-6
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Publication
23121557 | -
First Author: Vinet J
Year: 2013
Journal: Br J Pharmacol
Title: Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR.
Volume: 168
Issue: 6
Pages: 1375-87
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Publication
16791897 | -
First Author: Comerford I
Year: 2006
Journal: Eur J Immunol
Title: The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro.
Volume: 36
Issue: 7
Pages: 1904-16
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Protein Domain
IPR005383 | ACKR4
Type: Family
Description: Just like classical chemokine receptors, atypical chemokine receptors (ACKRs) are seven-transmembrane-helix (7TM) receptors that bind chemokines []. However, they lack the canonical DRYLAIV motif necessary for GPCR coupling to G proteins and induction of classical signalling pathways. Instead, ACKRs internalise their chemokine ligands, which may subsequently affect chemokine availability. The ACKR family comprises five members: Duffy Antigen Receptor for Chemokines (DARC, ACKR1), D6 (ACKR2), CXCR7 (ACKR3), CCRL1 (ACKR4) and CCRL2 (ACKR5) [].Atypical chemokine receptor 4 (ACKR4/CCRL1/CCX-CKR) binds and scavenges the ligands of the chemokine receptors CCR7 and CCR9 (CCL19/CCL21 and CCL25, respectively) and targets them for subsequent lysosomal degradation [, ]. Apart from being a scavenger for chemokines, it may prevent CXCR3-induced chemotaxis by heteromerisation []. ACKR4 appears to have a mayor role in normal thymus development and function [].
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HT Experiment
GSE33306 | Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L (hnRNP L) regulates development, proliferation and migration of thymic pre-T cells
Series Id: E-GEOD-33306
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11123313 | J:66381
First Author: Nakano H
Year: 2001
Journal: J Immunol
Title: Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation.
Volume: 166
Issue: 1
Pages: 361-9
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Publication
15534368 | J:94536
First Author: Qu C
Year: 2004
Journal: J Exp Med
Title: Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes.
Volume: 200
Issue: 10
Pages: 1231-41
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Protein
P84444
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein
P86793
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein
P86792
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein Coding Gene
MGI:1913150 | Trem2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0028180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0028185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028143 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1346316 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1349183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0026876 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9653094 | J:57559
First Author: Ngo VN
Year: 1998
Journal: J Exp Med
Title: Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells.
Volume: 188
Issue: 1
Pages: 181-91
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Publication
8405042 | J:15290
First Author: Nakano H
Year: 1993
Journal: Eur J Immunol
Title: Nonspecific augmentation of lymph node T cells and I-E-independent selective deletion of V beta 14+ T cells by Mtv-2 in the DDD mouse.
Volume: 23
Issue: 10
Pages: 2434-9
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Publication
9927507 | J:52567
First Author: Gunn MD
Year: 1999
Journal: J Exp Med
Title: Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization.
Volume: 189
Issue: 3
Pages: 451-60
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Publication
12750361 | J:83721
First Author: Yoshino M
Year: 2003
Journal: Int Immunol
Title: Distinct antigen trafficking from skin in the steady and active states.
Volume: 15
Issue: 6
Pages: 773-9
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Publication
10620605 | J:112425
First Author: Stein JV
Year: 2000
Journal: J Exp Med
Title: The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules.
Volume: 191
Issue: 1
Pages: 61-76
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Publication
9022021 | J:47819
First Author: Nakano H
Year: 1997
Journal: Eur J Immunol
Title: Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes.
Volume: 27
Issue: 1
Pages: 215-21
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Publication
11801633 | J:73951
First Author: Chen SC
Year: 2002
Journal: J Immunol
Title: Central nervous system inflammation and neurological disease in transgenic mice expressing the CC chemokine CCL21 in oligodendrocytes.
Volume: 168
Issue: 3
Pages: 1009-17
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Publication
16047341 | J:100432
First Author: Bouma G
Year: 2005
Journal: Eur J Immunol
Title: Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre-diabetic islets in NOD mice.
Volume: 35
Issue: 8
Pages: 2386-96
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Publication
27021907 | J:315437
First Author: Kim S
Year: 2016
Journal: Immunobiology
Title: Impaired spleen structure and chemokine expression in ME7 scrapie-infected mice.
Volume: 221
Issue: 8
Pages: 871-8
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GXD Expression
GXD Expression
     
Probe: MGI:3847732
Assay Type: RT-PCR
Annotation Date: 2009-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627219
Stage: TS19
Assay Id: MGI:3848127
Age: embryonic day 11.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3847732
Assay Type: RT-PCR
Annotation Date: 2009-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1658619
Stage: TS19
Assay Id: MGI:3848127
Age: embryonic day 11.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3847732
Assay Type: RT-PCR
Annotation Date: 2009-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1658619
Stage: TS19
Assay Id: MGI:3848207
Age: embryonic day 11.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3847732
Assay Type: RT-PCR
Annotation Date: 2009-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1658619
Stage: TS19
Assay Id: MGI:3848207
Age: embryonic day 11.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454916
Age: postnatal week 6-8
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454916
Age: postnatal week 6-8
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543128
Stage: TS28
Assay Id: MGI:4454916
Age: postnatal week 6-8
Specimen Label: WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543128
Stage: TS28
Assay Id: MGI:4454916
Age: postnatal week 6-8
Specimen Label: KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454917
Age: postnatal week 6-8
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454917
Age: postnatal week 6-8
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543128
Stage: TS28
Assay Id: MGI:4454917
Age: postnatal week 6-8
Specimen Label: WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543128
Stage: TS28
Assay Id: MGI:4454917
Age: postnatal week 6-8
Specimen Label: KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Stage: TS21
Assay Id: MGI:4454925
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Stage: TS23
Assay Id: MGI:4454925
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876825
Stage: TS25
Assay Id: MGI:4454925
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876827
Stage: TS27
Assay Id: MGI:4454925
Age: postnatal day 1
Specimen Label: 1d
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454925
Age: postnatal day 10
Specimen Label: 10d
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454925
Age: postnatal week 6
Specimen Label: 6w
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4454908
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454925
Age: postnatal month 6
Specimen Label: 6m
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Stage: TS21
Assay Id: MGI:4454926
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Stage: TS23
Assay Id: MGI:4454926
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876825
Stage: TS25
Assay Id: MGI:4454926
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876827
Stage: TS27
Assay Id: MGI:4454926
Age: postnatal day 1
Specimen Label: 1d
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454926
Age: postnatal day 10
Specimen Label: 10d
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454926
Age: postnatal week 6
Specimen Label: 6w
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4454909
Assay Type: RT-PCR
Annotation Date: 2010-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4454926
Age: postnatal month 6
Specimen Label: 6m
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7550620
Assay Type: RT-PCR
Annotation Date: 2023-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7550715
Age: postnatal week 1
Image: 4
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7550620
Assay Type: RT-PCR
Annotation Date: 2023-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7550715
Age: postnatal week 1
Image: 4
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7550621
Assay Type: RT-PCR
Annotation Date: 2023-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7550716
Age: postnatal week 1
Image: 4
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7550621
Assay Type: RT-PCR
Annotation Date: 2023-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7550716
Age: postnatal week 1
Image: 4
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185717
Pattern: Single cells
Stage: TS17
Assay Id: MGI:6437763
Age: embryonic day 10.5
Note: Expression is in cells near the cardinal vein.
Specimen Label: 1K
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5638398
Assay Type: RNA in situ
Annotation Date: 2015-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1902825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5638405
Age: embryonic day 17.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713284
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells
Specimen Label: 3D
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713284
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells
Specimen Label: 3D
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7713284
Age: embryonic day 11.5
Note: Expression only in a subset of lymphatic endothelial cells.
Specimen Label: 6I
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7713284
Age: embryonic day 11.5
Note: Expression only in a subset of lymphatic endothelial cells.
Specimen Label: 6I
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7713284
Age: embryonic day 12.5
Note: Expression restricted to budding lymphatic endothelial cells.
Specimen Label: 2D
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7713284
Age: embryonic day 12.5
Note: Expression restricted to budding lymphatic endothelial cells.
Specimen Label: 2D
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722096
Assay Type: RNA in situ
Annotation Date: 2007-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3723080
Age: embryonic day 10.5
Image: 3C
Note: Expression was detected in the dorso-anterior parathyroid domain of the third pouch.
Specimen Label: 3C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722096
Assay Type: RNA in situ
Annotation Date: 2007-10-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1675817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3723080
Age: embryonic day 10.5
Image: 3D
Note: Expression was detected in the dorso-anterior parathyroid domain of the third pouch.
Specimen Label: 3D
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3722096
Assay Type: RNA in situ
Annotation Date: 2007-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:3723080
Age: embryonic day 11.5
Image: 4B
Note: Expression was detected in the parathyroid domain of the third pouch.
Specimen Label: 4B
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3722096
Assay Type: RNA in situ
Annotation Date: 2007-10-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1675819
Stage: TS19
Assay Id: MGI:3723080
Age: embryonic day 11.5
Image: 4C
Note: Expression was absent from the parathyroid domain of the third pouch.
Specimen Label: 4C
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5638398
Assay Type: RNA in situ
Annotation Date: 2015-06-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287423
Stage: TS23
Assay Id: MGI:5638405
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6788
Specimen Label: GUDMAP:6788
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5000636
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541196
Age: embryonic day 15.5
Image: GUDMAP:6789
Specimen Label: GUDMAP:6789
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1635415
Stage: TS15
Assay Id: MGI:6437763
Age: embryonic day 9.5
Specimen Label: 1E
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3848010
Assay Type: Immunohistochemistry
Annotation Date: 2009-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1658619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3848218
Age: embryonic day 11.5
Specimen Label: 8B/C Wt #1
Detected: true
Specimen Num: 1
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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