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Search results 601 to 700 out of 1314 for Cd28

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Hits by Strain

Type Details Score
Allele
Cd28<tm1Mak> | MGI:1857150
Name: CD28 antigen; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd28<tm1(KOMP)Vlcg> | MGI:4399550
Name: CD28 antigen; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd28<tm1.1Huen> | MGI:5461540
Name: CD28 antigen; targeted mutation 1.1, Thomas Hunig
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Cd28<tm1.1(CD28)Geno> | MGI:6402766
Name: CD28 antigen; targeted mutation 1.1, Genoway
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd28<em2(CD28)Gpt> | MGI:7572965
Name: CD28 antigen; endonuclease-mediated mutation 2, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd28<em3(CD28)Gpt> | MGI:7572979
Name: CD28 antigen; endonuclease-mediated mutation 3, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7751777 | C57BL/6JSmoc-Cd28<em1(CD28)Smoc> Pdcd1<em1(PDCD1)Smoc> Cd274<em1(CD274)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
11903060 | -
First Author: Tao L
Year: 2002
Journal: Biochem J
Title: Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.
Volume: 363
Issue: Pt 1
Pages: 175-82
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Interaction Experiment
Klasen S (1998)
Description: Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein.
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Strain
MGI:7751757 | C57BL/6JSmoc-Cd28<em2(CD28)Smoc> Cd38<em2(hCD38)Smoc> In(9CD3D,CD3E,CD3G)1Smoc/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Pathway
R-MMU-388841 | Regulation of T cell activation by CD28 family
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Strain
MGI:2162616 | B6.129S2-Cd28<tm1Mak>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4453588 | B6.129S2-Cd28<tm1Mak>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3620228 | NOD.129S2-Cd28<tm1Mak>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2663283 | NOD.129S2(B6)-Cd28<tm1Mak>/JbsJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2162009 | C.129S2(B6)-Cd28<tm1Mak>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7610750 | B6;129S2-Cd28<tm1Mak>/Rbrc
Attribute String: mutant stock, targeted mutation
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Allele
Cd28<tm1Pjl> | MGI:2664380
Name: CD28 antigen; targeted mutation 1, Philip J Lucas
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd28<tm1Shr> | MGI:3721239
Name: CD28 antigen; targeted mutation 1, Arlene H Sharpe
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd28<tm1Jmg> | MGI:3722546
Name: CD28 antigen; targeted mutation 1, Jonathan M Green
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Cd28<tm2.1Jmg> | MGI:3850854
Name: CD28 antigen; targeted mutation 2.1, Jonathan M Green
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Cd28<tm1e(EUCOMM)Hmgu> | MGI:4434605
Name: CD28 antigen; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd28<tm1a(EUCOMM)Hmgu> | MGI:4435635
Name: CD28 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd28<tm1Ltu> | MGI:5485211
Name: CD28 antigen; targeted mutation 1, Laurence A Turka
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6402771 | C57BL/6N-Cd28<tm1.1(CD28)Geno>/Geno
Attribute String: targeted mutation, mutant strain, coisogenic
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Allele
Cd28<em1Gpt> | MGI:7296556
Name: CD28 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd28<em6Gpt> | MGI:7296557
Name: CD28 antigen; endonuclease-mediated mutation 6, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6349660 | C57BL/6JGpt-Cd28<em3(CD28)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd28<em3Smoc> | MGI:7623904
Name: CD28 antigen; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: NOD.129S2-Cd28
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas * NOD
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: B6.129S2-Cd28
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: B6.129S2-Cd28/J
Zygosity: hm
Has Mutant Allele: true
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Protein
P09793
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q9WUL5
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Protein
Q9EP73
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
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Protein
Q9JHJ8
Organism: Mus musculus/domesticus
Length: 322  
Fragment?: false
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DO Term
DOID:0111937 | immunodeficiency 22
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Strain
MGI:4462065 | 129S4/SvJae-Cd28<tm1Shr>/Mmucd
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:3851098 | B6.129X1-Cd28<tm1Jmg>
Attribute String: congenic, targeted mutation
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Strain
MGI:4836215 | B6.129X1-Cd28<tm1Jmg>/Mmjax
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4836217 | B6.129X1-Cd28<tm2.1Jmg>/Mmjax
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3851097 | B6.129X1-Cd28<tm2.1Jmg>
Attribute String: targeted mutation, congenic
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Strain
MGI:5556473 | B6NTac;B6N-Cd28<tm1a(EUCOMM)Hmgu>/H
Attribute String: mutant strain, targeted mutation
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Strain
MGI:5781937 | C57BL/6N-Cd28<tm1a(EUCOMM)Hmgu>/H
Attribute String: coisogenic, targeted mutation
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Strain
MGI:5532196 | C57BL/6-Cd28<tm1Ltu>/J
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7624177 | C57BL/6JSmoc-Cd28<em3Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: B6.129X1-Cd28
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: B6.129X1-Cd28
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: C57BL/6N-Cd28/H
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:104879 | Pdcd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1354701 | Icosl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2658978 | Btla
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926446 | Cd274
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1930125 | Pdcd1lg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q02242
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
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Protein
Q7TSA3
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
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Publication
10382746 | -
First Author: Yang WC
Year: 1999
Journal: Eur J Immunol
Title: Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway.
Volume: 29
Issue: 6
Pages: 1842-9
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Publication
15214045 | -
First Author: Garçon F
Year: 2004
Journal: Eur J Immunol
Title: The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.
Volume: 34
Issue: 7
Pages: 1972-80
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Publication
22184754 | -
First Author: Wang T
Year: 2012
Journal: J Leukoc Biol
Title: K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation.
Volume: 91
Issue: 3
Pages: 449-59
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Publication
12165654 | -
First Author: Michel F
Year: 2002
Journal: Sci STKE
Title: CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76?
Volume: 2002
Issue: 144
Pages: pe35
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Publication
9694876 | -
First Author: Okkenhaug K
Year: 1998
Journal: J Biol Chem
Title: Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction.
Volume: 273
Issue: 33
Pages: 21194-202
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Publication
8621607 | -
First Author: Pagès F
Year: 1996
Journal: J Biol Chem
Title: Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association.
Volume: 271
Issue: 16
Pages: 9403-9
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Protein Coding Gene
MGI:88556 | Ctla4
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:3640404 | NOD.Cg-Cd40lg<tm1Flv> Cd28<tm1Mak>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5604710 | NOD.Cg-Cd28<tm1Mak> H2<h4>/HbmMmmh
Attribute String: major histocompatibility congenic, mutant strain, congenic, targeted mutation
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Strain
MGI:6352479 | C57BL/6-Pdcd1<em6(PDCD1)Gpt> Cd28<em2(CD28)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Cd28/Cd28 Tg(DO11.10)10Dlo/?
Background: involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Cd40lg/Cd40lg
Background: NOD.Cg-Cd40lg Cd28
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Cd5/Cd5
Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Tg(H2-K-Cd86)27All/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Tg(H2-K-Cd86)7All/?
Background: involves: BALB/c * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Tg(TcrLCMV)327Sdz/?
Background: involves: 129S2/SvPas * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Ndfip1/Ndfip1
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Publication
11343123 | J:66702
First Author: Tafuri A
Year: 2001
Journal: Nature
Title: ICOS is essential for effective T-helper-cell responses.
Volume: 409
Issue: 6816
Pages: 105-9
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Protein Domain
IPR039943 | ICOS
Type: Family
Description: ICOS is an inducible T-cell co-stimulator with homology to CD28 []. CD28 and ICOS function similarly during expansion, survival and differentiation of T cells. They are necessary for proper IgG responses. However, CD28 induces IL-2 production, while ICOS is more potent in the induction of IL-10 production [].
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Strain
MGI:5767204 | C.129S2(B6)-Cd28<tm1Mak> Stat6<tm1Gru>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:5638707 | NOD.Cg-Cd28<tm1Mak> Ifng<tm1Ts> H2<h4>/HbmMmmh
Attribute String: congenic, major histocompatibility congenic, mutant strain, variant allele
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Strain
MGI:3721980 | C.129S4-Cd28<tm1Shr> Ctla4<tm1Shr>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4453168 | C.129S4-Ctla4<tm1Shr> Cd28<tm1Shr>/Mmnc
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4453167 | 129S4-Ctla4<tm1Shr> Cd28<tm1Shr>/Mmnc
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5461374 | B6.129S4-Cd28<tm1Shr> Ctla4<tm1Shr>/J
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4441204 | either: B6.Cg-Cd28<tm1Pjl> Tnfrsf9<tm1Byk> or C.Cg-Cd28<tm1Pjl> Tnfrsf9<tm1Byk>
Attribute String: Not specified
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Strain
MGI:4441205 | B6.Cg-Cd28<tm1Pjl> Tnfrsf9<tm1Byk>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4441206 | C.Cg-Cd28<tm1Pjl> Tnfrsf9<tm1Byk>
Attribute String: targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Cd28/Cd28 Tnfsf9/Tnfsf9
Background: involves: 129 * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Stat6/Stat6
Background: C.129S2(B6)-Cd28 Stat6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Tnfrsf9/Tnfrsf9
Background: either: B6.Cg-Cd28 Tnfrsf9 or C.Cg-Cd28 Tnfrsf9
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28<+> Cd5/Cd5
Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Cd5/Cd5<+>
Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Ctla4/Ctla4
Background: C.129S4-Cd28 Ctla4
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Tnfsf14/Tnfsf14
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd28/Cd28 Rc3h1/Rc3h1<+>
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6JSfdAnu
Zygosity: cx
Has Mutant Allele: true
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