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Search results 601 to 700 out of 1036 for Cd5

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Type Details Score
Publication
38159726 | J:355310
First Author: Zhang B
Year: 2024
Journal: Mucosal Immunol
Title: Metabolic fitness of IgA(+) plasma cells in the gut requires DOCK8.
Volume: 17
Issue: 3
Pages: 431-449
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Publication
30237510 | J:279440
First Author: Chen MY
Year: 2019
Journal: Cell Death Differ
Title: PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency.
Volume: 26
Issue: 7
Pages: 1221-1234
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Publication
34845392 | J:320901
First Author: Di Pietro A
Year: 2022
Journal: Nat Immunol
Title: Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection.
Volume: 23
Issue: 1
Pages: 86-98
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Publication
26077717 | J:226355
First Author: Good-Jacobson KL
Year: 2015
Journal: J Exp Med
Title: c-Myb is required for plasma cell migration to bone marrow after immunization or infection.
Volume: 212
Issue: 7
Pages: 1001-9
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Publication
34539636 | J:311099
 
First Author: Schmiedel D
Year: 2021
Journal: Front Immunol
Title: Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation.
Volume: 12
Pages: 705848
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Publication
33306108 | J:308839
 
First Author: Saveliev A
Year: 2021
Journal: J Exp Med
Title: Efficient homing of antibody-secreting cells to the bone marrow requires RNA-binding protein ZFP36L1.
Volume: 218
Issue: 3
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Publication
34214192 | J:309561
First Author: Monzón-Casanova E
Year: 2021
Journal: Eur J Immunol
Title: Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice.
Volume: 51
Issue: 9
Pages: 2266-2273
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Publication
27986456 | J:240634
First Author: Grajkowska LT
Year: 2017
Journal: Immunity
Title: Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification.
Volume: 46
Issue: 1
Pages: 65-77
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Genotype
Genotype
Symbol: Rtcb/Rtcb Tg(Fcer2a-cre)5Mbu/?
Background: involves: C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Fcer2a-cre)5Mbu/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
15664155 | J:96277
First Author: Xu Y
Year: 2005
Journal: Immunity
Title: Lyn tyrosine kinase: accentuating the positive and the negative.
Volume: 22
Issue: 1
Pages: 9-18
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Publication
17127394 | -
 
First Author: Sampson M
Year: 2007
Journal: Front Biosci
Title: Src kinases in G-CSF receptor signaling.
Volume: 12
Pages: 1463-74
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Protein Domain
IPR035748 | Lyn_SH3
Type: Domain
Description: Lyn is a member of the Src subfamily of proteins, which are cytoplasmic (or non-receptor) PTKs. Lyn is expressed in B lymphocytes and myeloid cells. It exhibits both positive and negative regulatory roles in B cell receptor (BCR) signaling. Lyn, as well as Fyn and Blk, promotes B cell activation by phosphorylating ITAMs (immunoreceptor tyr activation motifs) in CD19 and in Ig components of BCR []. It negatively regulates signaling by its unique ability to phosphorylate ITIMs (immunoreceptor tyr inhibition motifs) in cell surface receptors like CD22 and CD5 []. Lyn also plays an important role in G-CSF receptor signaling by phosphorylating a variety of adaptor molecules []. Src kinases contain an N-terminal SH4 domain with a myristoylation site, followed by SH3 and SH2 domains, a tyr kinase domain, and a regulatory C-terminal region containing a conserved tyr. They are activated by autophosphorylation at the tyr kinase domain, but are negatively regulated by phosphorylation at the C-terminal tyr by Csk (C-terminal Src Kinase). The SH3 domain of Src kinases contributes to substrate recruitment by binding adaptor proteins/substrates, and regulation of kinase activity through an intramolecular interaction [, ].
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Publication
9611252 | J:48250
First Author: Iwama A
Year: 1998
Journal: Nucleic Acids Res
Title: Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
Volume: 26
Issue: 12
Pages: 3034-43
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Publication
11567635 | J:71804
First Author: Sosinowski T
Year: 2001
Journal: Immunity
Title: The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.
Volume: 15
Issue: 3
Pages: 457-66
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Publication
16107703 | J:100408
First Author: Simeoni L
Year: 2005
Journal: Mol Cell Biol
Title: The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions.
Volume: 25
Issue: 17
Pages: 7557-68
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Publication
11313408 | J:266143
First Author: Kingsbury GA
Year: 2001
Journal: J Immunol
Title: Cloning, expression, and function of BLAME, a novel member of the CD2 family.
Volume: 166
Issue: 9
Pages: 5675-80
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Publication
12645942 | J:115705
First Author: Ulivieri C
Year: 2003
Journal: Eur J Immunol
Title: Normal B-1 cell development but defective BCR signaling in Lck-/- mice.
Volume: 33
Issue: 2
Pages: 441-5
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Publication
31019259 | J:298414
First Author: Wirasinha RC
Year: 2019
Journal: Cell Death Differ
Title: Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells.
Volume: 26
Issue: 12
Pages: 2727-2739
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Publication
22645349 | J:185522
First Author: Weber KS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Distinct CD4+ helper T cells involved in primary and secondary responses to infection.
Volume: 109
Issue: 24
Pages: 9511-6
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Publication
20137986 | J:157928
First Author: Cho JH
Year: 2010
Journal: Immunity
Title: T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis.
Volume: 32
Issue: 2
Pages: 214-26
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Publication
24759759 | J:215168
First Author: Burkhard SH
Year: 2014
Journal: PLoS One
Title: T cell contamination in flow cytometry gating approaches for analysis of innate lymphoid cells.
Volume: 9
Issue: 4
Pages: e94196
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Publication
17227833 | J:145323
First Author: Rowbotham NJ
Year: 2007
Journal: Blood
Title: Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation.
Volume: 109
Issue: 9
Pages: 3757-66
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Publication
31433296 | J:278696
   
First Author: Savage HP
Year: 2019
Journal: Elife
Title: TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections.
Volume: 8
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Publication
25978037 | J:235318
First Author: Barra MM
Year: 2015
Journal: PLoS One
Title: Premature expression of Foxp3 in double-negative thymocytes.
Volume: 10
Issue: 5
Pages: e0127038
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Publication
24266404 | J:211840
First Author: Siggs OM
Year: 2014
Journal: Immunology
Title: A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction.
Volume: 141
Issue: 4
Pages: 587-95
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Publication
34895467 | J:320780
   
First Author: Kim S
Year: 2021
Journal: Elife
Title: Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua.
Volume: 10
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Publication
29541070 | J:313984
 
First Author: Kim G
Year: 2018
Journal: Front Immunol
Title: Transcription Factor KLF10 Constrains IL-17-Committed Vγ4+ γδ T Cells.
Volume: 9
Pages: 196
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Publication
11369705 | J:69777
First Author: Kikuchi K
Year: 2001
Journal: Int Immunol
Title: Suppression of thymic development by the dominant-negative form of Gads.
Volume: 13
Issue: 6
Pages: 777-83
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Publication
15357954 | J:93928
First Author: Dal Porto JM
Year: 2004
Journal: Immunity
Title: Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck.
Volume: 21
Issue: 3
Pages: 443-53
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Publication
25419629 | J:222610
First Author: Fulton RB
Year: 2015
Journal: Nat Immunol
Title: The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens.
Volume: 16
Issue: 1
Pages: 107-17
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Allele
Il6st<tm2Thir> | MGI:2386993
Name: interleukin 6 signal transducer; targeted mutation 2, Toshio Hirano
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Cd79a<tm1.1Cgn> | MGI:2388326
 
Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 1.1, University of Cologne
Allele Type: Targeted
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Allele
Plcl2<tm1Tta> | MGI:2679632
Name: phospholipase C-like 2; targeted mutation 1, Tadaomi Takenawa
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Malt1<tm1Vmd> | MGI:2684761
Name: MALT1 paracaspase; targeted mutation 1, Vishva M Dixit
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Card11<tm1Litt> | MGI:3039682
Name: caspase recruitment domain family, member 11; targeted mutation 1, Dan R Littman
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cr2<tm1.1Jhws> | MGI:4417922
Name: complement receptor 2; targeted mutation 1.1, John Weiss
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Mirc30<tm1.2Rdf> | MGI:4437041
Name: microRNA cluster 30, including Mir16-1 through Mir15a; targeted mutation 1.2, Riccardo Dalla-Favera
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Mirc30<tm1.1Rdf> | MGI:4437043
Name: microRNA cluster 30, including Mir16-1 through Mir15a; targeted mutation 1.1, Riccardo Dalla-Favera
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Themis<m1Btlr> | MGI:5575394
 
Name: thymocyte selection associated; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Allele
Pik3cd<m2Btlr> | MGI:5806440
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Ighm/Ighm
Background: B6.129S-Ighm
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ighm/Ighm Tg(Igh-6)1Msn/?
Background: B6.129S-Ighm
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ighm/Ighm
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il6st/Il6st
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irf8/Irf8
Background: B6.129P2-Irf8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh-J/Igh-J
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: C57BL/6J-Cd22
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pik3r1/Pik3r1
Background: C57BL/6J-Pik3r1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkdc/Prkdc
Background: C57BL/6J-Prkdc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Plcg2/Plcg2
Background: C57BL/6J-Plcg2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk4/Stk4
Background: C57BL/6J-Stk4
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:3028467 | C57BL/6J
Attribute String: inbred strain
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Strain
MGI:2684695 | DBA/2J
Attribute String: inbred strain
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Protein Coding Gene
MGI:88319 | Cd19
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2447166 | Cmtm7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2443630 | Siglecg
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Gimap1<tm1.1Gwb> | MGI:4459837
Name: GTPase, IMAP family member 1; targeted mutation 1.1, Geoffrey W Butcher
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tnfaip3<tm1.1Awai> | MGI:5291646
Name: tumor necrosis factor, alpha-induced protein 3; targeted mutation 1.1, Ari Waisman
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Rnf31<tm1.1Kiwa> | MGI:5550368
Name: ring finger protein 31; targeted mutation 1.1, Kazuhiro Iwai
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Ikzf1<tm1.1Smale> | MGI:5563075
 
Name: IKAROS family zinc finger 1; targeted mutation 1.1, Stephen T Smale
Allele Type: Targeted
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Allele
Ptpn6<m3Btlr> | MGI:5789594
Name: protein tyrosine phosphatase, non-receptor type 6; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Ebf1<m2Btlr> | MGI:6199990
Name: early B cell factor 1; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Xrcc5<m1Btlr> | MGI:6304305
Name: X-ray repair complementing defective repair in Chinese hamster cells 5; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Card11<em2Welu> | MGI:6491989
Name: caspase recruitment domain family, member 11; endonuclease-mediated mutation 2, Wei Lu
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Ikzf1/Ikzf1
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Blnk/Blnk
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rorc/Rorc
Background: C57BL/6J-Rorc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pnp/Pnp
Background: C57BL/6J-Pnp
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnip1/Tnip1
Background: C57BL/6J-Tnip1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Card11/Card11
Background: C57BL/6J-Card11
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Card11/Card11
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
32849556 | J:308206
 
First Author: Chodisetti SB
Year: 2020
Journal: Front Immunol
Title: TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner.
Volume: 11
Pages: 1632
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Publication
29880490 | J:284967
First Author: Centa M
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis.
Volume: 38
Issue: 8
Pages: e145-e158
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Publication
32236527 | J:322129
First Author: Chappaz S
Year: 2020
Journal: Blood Adv
Title: Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice.
Volume: 4
Issue: 7
Pages: 1270-1283
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Publication
27261530 | J:236268
First Author: Wöhner M
Year: 2016
Journal: J Exp Med
Title: Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development.
Volume: 213
Issue: 7
Pages: 1201-21
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Publication
24591370 | J:209874
First Author: Willis SN
Year: 2014
Journal: J Immunol
Title: Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism.
Volume: 192
Issue: 7
Pages: 3200-6
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Publication
31412245 | J:288870
First Author: Sheikh AA
Year: 2019
Journal: Cell Rep
Title: Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.
Volume: 28
Issue: 7
Pages: 1758-1772.e4
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Publication
25215539 | J:222517
First Author: Chen MY
Year: 2014
Journal: PLoS One
Title: PP4 is essential for germinal center formation and class switch recombination in mice.
Volume: 9
Issue: 9
Pages: e107505
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Publication
34762046 | J:347560
   
First Author: Lehrke MJ
Year: 2021
Journal: Elife
Title: The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice.
Volume: 10
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Publication
31747599 | J:298891
First Author: Ly A
Year: 2019
Journal: Cell Rep
Title: Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria.
Volume: 29
Issue: 8
Pages: 2257-2269.e6
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Publication
27217539 | J:234772
First Author: Gloury R
Year: 2016
Journal: J Exp Med
Title: Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.
Volume: 213
Issue: 6
Pages: 1095-111
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Publication
32229726 | J:301898
First Author: Ricker E
Year: 2020
Journal: J Clin Invest
Title: Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
Volume: 130
Issue: 7
Pages: 3654-3670
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Publication
20194438 | J:157903
First Author: Yamaguchi T
Year: 2010
Journal: Genes Dev
Title: Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression.
Volume: 24
Issue: 5
Pages: 455-69
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Publication
24747299 | J:215189
First Author: Du Roure C
Year: 2014
Journal: PLoS One
Title: Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophils.
Volume: 9
Issue: 4
Pages: e92836
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Publication
35831623 | J:332913
First Author: Kong IY
Year: 2022
Journal: Cell Death Differ
Title: Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis.
Volume: 29
Issue: 12
Pages: 2519-2530
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Publication
23508106 | J:204030
First Author: Zhou X
Year: 2013
Journal: Mol Cell Biol
Title: Loss of an Igκ gene enhancer in mature B cells results in rapid gene silencing and partial reversible dedifferentiation.
Volume: 33
Issue: 10
Pages: 2091-101
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Publication
24980046 | J:214727
First Author: Ghosh HS
Year: 2014
Journal: J Exp Med
Title: ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2.
Volume: 211
Issue: 8
Pages: 1623-35
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Publication
28423310 | J:271263
First Author: Piovesan D
Year: 2017
Journal: Cell Rep
Title: c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses.
Volume: 19
Issue: 3
Pages: 461-470
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Publication
32023467 | J:287681
First Author: Robinson MJ
Year: 2020
Journal: Cell Rep
Title: The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers.
Volume: 30
Issue: 5
Pages: 1530-1541.e4
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Publication
29996102 | J:270676
First Author: Schulz O
Year: 2018
Journal: Cell Rep
Title: Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens.
Volume: 24
Issue: 2
Pages: 419-428
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Publication
36618345 | J:340155
 
First Author: Wöhner M
Year: 2022
Journal: Front Immunol
Title: The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells.
Volume: 13
Pages: 859598
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Publication
29791846 | J:270850
First Author: Hoogeboom R
Year: 2018
Journal: Cell Rep
Title: Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation.
Volume: 23
Issue: 8
Pages: 2342-2353
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Publication
30723095 | J:271215
First Author: Denton AE
Year: 2019
Journal: J Exp Med
Title: Type I interferon induces CXCL13 to support ectopic germinal center formation.
Volume: 216
Issue: 3
Pages: 621-637
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Allele
Pik3ap1<tm1Kuro> | MGI:2178861
Name: phosphoinositide-3-kinase adaptor protein 1; targeted mutation 1, Tomohiro Kurosaki
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ighm<tm1Msn> | MGI:2447178
Name: immunoglobulin heavy constant mu; targeted mutation 1, Michael S Neuberger
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd79a<tm5.1Cgn> | MGI:3047539
Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 5.1, University of Cologne
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Irf8<myls> | MGI:3578920
 
Name: interferon regulatory factor 8; myeloproliferative syndrome
Allele Type: Spontaneous
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Allele
Bank1<tm1Kuro> | MGI:3686872
Name: B cell scaffold protein with ankyrin repeats 1; targeted mutation 1, Tomohiro Kurosaki
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Igh<tm1Leck> | MGI:3830835
Name: immunoglobulin heavy chain complex; targeted mutation 1, Laurel A Eckhardt
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Modified regulatory region, Null/knockout
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