Type |
Details |
Score |
Genotype |
Symbol: |
Atmin/Atmin Cd79a/Cd79a<+> |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rnf31/Rnf31 Cd79a/Cd79a<+> |
Background: |
involves: BALB/c * C57BL/6NCrlj * CBA/JNCrlj |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Ikzf1/Ikzf1 |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atmin/Atmin Cd79a/Cd79a<+> |
Background: |
B6.Cg-Cd79a Atmin |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Dynll1/Dynll1 |
Background: |
B6.Cg-Dynll1 Cd79a |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Ctnnbl1/Ctnnbl1 |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cnn3/Cnn3 Cd79a/Cd79a<+> |
Background: |
involves: 129S6/SvEvTac * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Slc39a10/Slc39a10 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Mzb1/Mzb1 |
Background: |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Orai1/Orai1 |
Background: |
involves: BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Phf5a/Phf5a |
Background: |
involves: BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Orai3/Orai3 |
Background: |
involves: BALB/c * C57BL/6J * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Eif4a1/Eif4a1 |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Elavl1/Elavl1 |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Cnot3/Cnot3 |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Tet2/Tet2 |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Tet3/Tet3 |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dnmt1/Dnmt1 Cd79a/Cd79a<+> |
Background: |
involves: 129S4/SvJae * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atmin/Atmin Cd79a/Cd79a<+> Tg(IghMyc)22Bri/? |
Background: |
B6.Cg-Cd79a Atmin Tg(IghMyc)22Bri |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Klf2/Klf2 |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
Background: |
involves: 129X1/SvJ * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfatc1/Nfatc1 Cd79a/Cd79a<+> |
Background: |
involves: BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+> |
Background: |
involves: 129S6/SvEvTac * BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Nfkbiz/Nfkbiz |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+> |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Inpp5d/Inpp5d Cd79a/Cd79a<+> Tg(IghAb36-65)1Wys/? |
Background: |
involves: 129 * BALB/c * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Setdb1/Setdb1 |
Background: |
involves: BALB/c * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Usp39/Usp39 |
Background: |
involves: BALB/c * C57BL/6J * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
He X |
Year: |
2018 |
Journal: |
EMBO J |
Title: |
Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells. |
Volume: |
37 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The B-cell antigen receptor (BCR) consists of the membrane-bound immunoglobulin (mIg) comprising two heavy (H) and two light (L) chains and the signal-transducing Igalpha/Igbeta (CD79a/CD79b) heterodimer. This entry includes CD79a and CD79b. They contain an immunoreceptor tyrosine-based activation motif (ITAM) with two conserved tyrosines that are crucial for the development and maintenance of mature B cells []. Homologues are known from vertebrates. |
|
•
•
•
•
•
|
Strain |
Attribute String: |
chemically induced mutation, mutant stock |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Tg(Mx1-cre)1Cgn/? |
Background: |
involves: C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Bcl2l11/Bcl2l11 Dicer1/Dicer1 Cd79a/Cd79a<+> |
Background: |
involves: 129S1/Sv * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Dicer1/Dicer1 Tg(BCL2)22Wehi/? |
Background: |
involves: BALB/c * C57BL/6JWehi * SJL/JWehi |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dicer1/Dicer1 Cd79a/Cd79a<+> |
Background: |
involves: BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hdac1/Hdac1 Hdac2/Hdac2 Cd79a/Cd79a<+> |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stim1/Stim1 Stim2/Stim2 Cd79a/Cd79a<+> |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sh3kbp1/Sh3kbp1 Cd79a/Cd79a<+> Gt(ROSA)26Sor/? |
Background: |
involves: BALB/c * C57BL/6 * NZB |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Huwe1/? Trp53/Trp53 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Bcl6/Bcl6 Cd79a/Cd79a<+> Tg(Cd4-cre)1Cwi/? |
Background: |
involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atmin/Atmin Trp53/Trp53 Cd79a/Cd79a<+> |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+> |
Background: |
involves: 129S1/Sv * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tbc1d10c/Tbc1d10c Cd79a/Cd79a<+> |
Background: |
involves: 129S2/SvPas * BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ikzf1/Ikzf1 Cd79a/Cd79a<+> Rag2/Rag2 |
Background: |
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Dynll1/Dynll1 Tg(IghMyc)22Bri/? |
Background: |
B6.Cg-Dynll1 Cd79a Tg(IghMyc)22Bri |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cnn2/Cnn2 Cnn3/Cnn3 Cd79a/Cd79a<+> |
Background: |
involves: 129S6/SvEvTac * 129X1/SvJ * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tcf3/Tcf3<+> Cd79a/Cd79a<+> |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Blnk/Blnk Cd79a/Cd79a Mzb1/Mzb1 |
Background: |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Commd8/Commd8 Igh/Igh<+> Cd79a/Cd79a<+> |
Background: |
involves: 129P2/OlaHsd * BALB/c * C57BL/6NSlc * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Orai1/Orai1 Orai3/Orai3 |
Background: |
involves: BALB/c * C57BL/6J * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Tet2/Tet2 Tet3/Tet3 |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Mef2c/Mef2c Mef2d/Mef2d |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ahr/Ahr Cd79a/Cd79a<+> |
Background: |
involves: 129 * BALB/c * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Hdac1/Hdac1 Hdac2/Hdac2 |
Background: |
involves: 129P2/OlaHsd * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Michael S Neuberger |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ssb/Ssb Cd79a/Cd79a<+> |
Background: |
involves: 129S/SvEv * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Nr4a1/Nr4a1 Nr4a3/Nr4a3 |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dicer1/Dicer1 Tg(IghelMD4)4Ccg/? Cd79a/Cd79a<+> |
Background: |
involves: BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fcgr2b/Fcgr2b Traf3ip2/Traf3ip2 Cd79a/Cd79a<+> |
Background: |
involves: 129S4/SvJae * BALB/c * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+> Tg(IghMyc)22Bri/? |
Background: |
B6.Cg-Bcl2l11 Cd79a Atmin Tg(IghMyc)22Bri |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Phf5a/Phf5a Tg(IghelMD4)4Ccg/? |
Background: |
involves: BALB/c * C57BL/6 * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Eif4b/Eif4b Eif4h/Eif4h |
Background: |
involves: BALB/c * C57BL/6 * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b |
Background: |
involves: 129S1/Sv * BALB/c |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a |
Background: |
involves: C57BL/6 * CBA |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b |
Background: |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Igh/Igh |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b |
Background: |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b |
Background: |
involves: 129/Sv * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b |
Background: |
involves: 129P2/OlaHsd |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Rasgrp1/Rasgrp1 |
Background: |
involves: C57BL/6JSfdAnu * CBA/J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfatc1/Nfatc1 Nfatc2/Nfatc2 Cd79a/Cd79a<+> |
Background: |
involves: BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Tg(Mx1-cre)1Cgn/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Tg(Cr2-cre)3Cgn/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Tg(Mx1-cre)1Cgn/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Tg(Cr2-cre)3Cgn/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Igh/Igh<+> |
Background: |
involves: BALB/c * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Igh/Igh<+> |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Rag1/Rag1 |
Background: |
involves: BALB/c |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Rag1/Rag1 |
Background: |
involves: BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Cd79b/Cd79b |
Background: |
involves: 129P2/OlaHsd |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a Cd79b/Cd79b<+> |
Background: |
involves: 129P2/OlaHsd |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79a/Cd79a<+> Igh/Igh<+> |
Background: |
involves: 129 * BALB/c * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+> |
Background: |
involves: 129S6/SvEvTac * BALB/c |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Xue HH |
Year: |
2007 |
Journal: |
Immunity |
Title: |
The transcription factor GABP is a critical regulator of B lymphocyte development. |
Volume: |
26 |
Issue: |
4 |
Pages: |
421-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto S |
Year: |
1994 |
Journal: |
Immunogenetics |
Title: |
The complete sequence of the human CD79b (Ig beta/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism. |
Volume: |
40 |
Issue: |
2 |
Pages: |
145-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2020 |
Journal: |
J Exp Med |
Title: |
Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing. |
Volume: |
217 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD79B antigen; targeted mutation 3, Michel C Nussenzweig |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+> Tg(BCL2)22Wehi/? |
Background: |
involves: 129S6/SvEvTac * BALB/c * C57BL/6JWehi * SJL/JWehi |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd79b/Cd79b |
Background: |
involves: 129/Sv * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Ackermann JA |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival. |
Volume: |
194 |
Issue: |
10 |
Pages: |
4650-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lukin K |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression. |
Volume: |
107 |
Issue: |
17 |
Pages: |
7869-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li W |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Core fucosylation of μ heavy chains regulates assembly and intracellular signaling of precursor B cell receptors. |
Volume: |
287 |
Issue: |
4 |
Pages: |
2500-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Havranek O |
Year: |
2017 |
Journal: |
Blood |
Title: |
Tonic B-cell receptor signaling in diffuse large B-cell lymphoma. |
Volume: |
130 |
Issue: |
8 |
Pages: |
995-1006 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li R |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. |
Volume: |
32 |
Issue: |
2 |
Pages: |
96-111 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teh YM |
Year: |
1997 |
Journal: |
J Exp Med |
Title: |
The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice. |
Volume: |
185 |
Issue: |
10 |
Pages: |
1753-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
220
 |
Fragment?: |
false |
|
•
•
•
•
•
|