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Search results 601 to 700 out of 702 for Cd79a

0.049s
Type Details Score
Genotype
Symbol: Atmin/Atmin Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rnf31/Rnf31 Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Ikzf1/Ikzf1
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Cd79a/Cd79a<+>
Background: B6.Cg-Cd79a Atmin
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Dynll1/Dynll1
Background: B6.Cg-Dynll1 Cd79a
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Ctnnbl1/Ctnnbl1
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cnn3/Cnn3 Cd79a/Cd79a<+>
Background: involves: 129S6/SvEvTac * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Slc39a10/Slc39a10
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Mzb1/Mzb1
Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Orai1/Orai1
Background: involves: BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Phf5a/Phf5a
Background: involves: BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Orai3/Orai3
Background: involves: BALB/c * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Eif4a1/Eif4a1
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Elavl1/Elavl1
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Cnot3/Cnot3
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Tet2/Tet2
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Tet3/Tet3
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Genotype
Symbol: Dnmt1/Dnmt1 Cd79a/Cd79a<+>
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Cd79a/Cd79a<+> Tg(IghMyc)22Bri/?
Background: B6.Cg-Cd79a Atmin Tg(IghMyc)22Bri
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Klf2/Klf2
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129X1/SvJ * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nfatc1/Nfatc1 Cd79a/Cd79a<+>
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+>
Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Nfkbiz/Nfkbiz
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Inpp5d/Inpp5d Cd79a/Cd79a<+> Tg(IghAb36-65)1Wys/?
Background: involves: 129 * BALB/c * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Setdb1/Setdb1
Background: involves: BALB/c * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Usp39/Usp39
Background: involves: BALB/c * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: He X
Year: 2018
Journal: EMBO J
Title: Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
Volume: 37
Issue: 11
Protein Domain
Type: Family
Description: The B-cell antigen receptor (BCR) consists of the membrane-bound immunoglobulin (mIg) comprising two heavy (H) and two light (L) chains and the signal-transducing Igalpha/Igbeta (CD79a/CD79b) heterodimer. This entry includes CD79a and CD79b. They contain an immunoreceptor tyrosine-based activation motif (ITAM) with two conserved tyrosines that are crucial for the development and maintenance of mature B cells []. Homologues are known from vertebrates.
Strain
Attribute String: chemically induced mutation, mutant stock
Genotype
Symbol: Cd79a/Cd79a Tg(Mx1-cre)1Cgn/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Dicer1/Dicer1 Cd79a/Cd79a<+>
Background: involves: 129S1/Sv * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Dicer1/Dicer1 Tg(BCL2)22Wehi/?
Background: involves: BALB/c * C57BL/6JWehi * SJL/JWehi
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dicer1/Dicer1 Cd79a/Cd79a<+>
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hdac1/Hdac1 Hdac2/Hdac2 Cd79a/Cd79a<+>
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Stim1/Stim1 Stim2/Stim2 Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sh3kbp1/Sh3kbp1 Cd79a/Cd79a<+> Gt(ROSA)26Sor/?
Background: involves: BALB/c * C57BL/6 * NZB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Huwe1/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl6/Bcl6 Cd79a/Cd79a<+> Tg(Cd4-cre)1Cwi/?
Background: involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Trp53/Trp53 Cd79a/Cd79a<+>
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+>
Background: involves: 129S1/Sv * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tbc1d10c/Tbc1d10c Cd79a/Cd79a<+>
Background: involves: 129S2/SvPas * BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ikzf1/Ikzf1 Cd79a/Cd79a<+> Rag2/Rag2
Background: involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Dynll1/Dynll1 Tg(IghMyc)22Bri/?
Background: B6.Cg-Dynll1 Cd79a Tg(IghMyc)22Bri
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cnn2/Cnn2 Cnn3/Cnn3 Cd79a/Cd79a<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tcf3/Tcf3<+> Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Blnk/Blnk Cd79a/Cd79a Mzb1/Mzb1
Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Commd8/Commd8 Igh/Igh<+> Cd79a/Cd79a<+>
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6NSlc * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Orai1/Orai1 Orai3/Orai3
Background: involves: BALB/c * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Tet2/Tet2 Tet3/Tet3
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Mef2c/Mef2c Mef2d/Mef2d
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ahr/Ahr Cd79a/Cd79a<+>
Background: involves: 129 * BALB/c * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Hdac1/Hdac1 Hdac2/Hdac2
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: cn
Has Mutant Allele: true
Allele
Name: transgene insertion, Michael S Neuberger
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Ssb/Ssb Cd79a/Cd79a<+>
Background: involves: 129S/SvEv * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Nr4a1/Nr4a1 Nr4a3/Nr4a3
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Genotype
Symbol: Dicer1/Dicer1 Tg(IghelMD4)4Ccg/? Cd79a/Cd79a<+>
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fcgr2b/Fcgr2b Traf3ip2/Traf3ip2 Cd79a/Cd79a<+>
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+> Tg(IghMyc)22Bri/?
Background: B6.Cg-Bcl2l11 Cd79a Atmin Tg(IghMyc)22Bri
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Phf5a/Phf5a Tg(IghelMD4)4Ccg/?
Background: involves: BALB/c * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Eif4b/Eif4b Eif4h/Eif4h
Background: involves: BALB/c * C57BL/6 * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129S1/Sv * BALB/c
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a
Background: involves: C57BL/6 * CBA
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Igh/Igh
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Rasgrp1/Rasgrp1
Background: involves: C57BL/6JSfdAnu * CBA/J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Nfatc1/Nfatc1 Nfatc2/Nfatc2 Cd79a/Cd79a<+>
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Tg(Cr2-cre)3Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Tg(Cr2-cre)3Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Igh/Igh<+>
Background: involves: BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Igh/Igh<+>
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Rag1/Rag1
Background: involves: BALB/c
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Rag1/Rag1
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Cd79b/Cd79b
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Igh/Igh<+>
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+>
Background: involves: 129S6/SvEvTac * BALB/c
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Xue HH
Year: 2007
Journal: Immunity
Title: The transcription factor GABP is a critical regulator of B lymphocyte development.
Volume: 26
Issue: 4
Pages: 421-31
Publication
First Author: Hashimoto S
Year: 1994
Journal: Immunogenetics
Title: The complete sequence of the human CD79b (Ig beta/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism.
Volume: 40
Issue: 2
Pages: 145-9
Publication  
First Author: Li X
Year: 2020
Journal: J Exp Med
Title: Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.
Volume: 217
Issue: 9
Allele  
Name: CD79B antigen; targeted mutation 3, Michel C Nussenzweig
Allele Type: Targeted
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd79a/Cd79a<+> Tg(BCL2)22Wehi/?
Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6JWehi * SJL/JWehi
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Cd79b/Cd79b
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Ackermann JA
Year: 2015
Journal: J Immunol
Title: Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.
Volume: 194
Issue: 10
Pages: 4650-6
Publication
First Author: Lukin K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression.
Volume: 107
Issue: 17
Pages: 7869-74
Publication
First Author: Li W
Year: 2012
Journal: J Biol Chem
Title: Core fucosylation of μ heavy chains regulates assembly and intracellular signaling of precursor B cell receptors.
Volume: 287
Issue: 4
Pages: 2500-8
Publication
First Author: Havranek O
Year: 2017
Journal: Blood
Title: Tonic B-cell receptor signaling in diffuse large B-cell lymphoma.
Volume: 130
Issue: 8
Pages: 995-1006
Publication
First Author: Li R
Year: 2018
Journal: Genes Dev
Title: Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming.
Volume: 32
Issue: 2
Pages: 96-111
Publication
First Author: Teh YM
Year: 1997
Journal: J Exp Med
Title: The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice.
Volume: 185
Issue: 10
Pages: 1753-8
Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false