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Search results 601 to 700 out of 965 for Csf1r

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Type Details Score
Publication
1673105 | J:11120
First Author: Siracusa LD
Year: 1991
Journal: Genetics
Title: Identification and applications of repetitive probes for gene mapping in the mouse.
Volume: 127
Issue: 1
Pages: 169-79
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1302014 | J:1064
First Author: Wilkie TM
Year: 1992
Journal: Nat Genet
Title: Evolution of the mammalian G protein alpha subunit multigene family.
Volume: 1
Issue: 2
Pages: 85-91
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32027825 | J:284925
     
First Author: Luo L
Year: 2020
Journal: Neuron
Title: Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.
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25826454 | J:229257
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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Publication
21308776 | J:233118
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
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11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
30635555 | J:270210
First Author: Loo L
Year: 2019
Journal: Nat Commun
Title: Single-cell transcriptomic analysis of mouse neocortical development.
Volume: 10
Issue: 1
Pages: 134
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30687013 | J:273531
 
First Author: Wlodarczyk A
Year: 2018
Journal: Front Cell Neurosci
Title: CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE.
Volume: 12
Pages: 523
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Publication
38100351 | J:349258
First Author: Miyauchi S
Year: 2023
Journal: Cell Rep
Title: Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18.
Volume: 42
Issue: 12
Pages: 113560
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Publication
31434879 | J:279495
First Author: Spangenberg E
Year: 2019
Journal: Nat Commun
Title: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Volume: 10
Issue: 1
Pages: 3758
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Publication
22729249 | J:187643
First Author: Wang Y
Year: 2012
Journal: Nat Immunol
Title: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia.
Volume: 13
Issue: 8
Pages: 753-60
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Publication
36624100 | J:352074
First Author: Johnson NR
Year: 2023
Journal: Nat Commun
Title: CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model.
Volume: 14
Issue: 1
Pages: 118
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Publication
33177990 | J:342993
 
First Author: Hou B
Year: 2020
Journal: Front Cell Neurosci
Title: Pharmacological Targeting of CSF1R Inhibits Microglial Proliferation and Aggravates the Progression of Cerebral Ischemic Pathology.
Volume: 14
Pages: 267
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Publication
30442669 | J:269032
First Author: Paschalis EI
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes.
Volume: 115
Issue: 48
Pages: E11359-E11368
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Publication
25088194 | J:259073
First Author: Patsialou A
Year: 2015
Journal: Oncogene
Title: Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells.
Volume: 34
Issue: 21
Pages: 2721-31
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Publication
29448957 | J:260587
First Author: Beckmann N
Year: 2018
Journal: Acta Neuropathol Commun
Title: Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.
Volume: 6
Issue: 1
Pages: 9
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Publication
33446487 | J:301527
 
First Author: Lei F
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Reply to Green and Hume: Nonmicroglia peripheral immune effects of short-term CSF1R inhibition with PLX5622.
Volume: 118
Issue: 4
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Publication
19058182 | J:146072
First Author: Mould AW
Year: 2009
Journal: Int J Cancer
Title: Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-beta signaling, decreased Gata6 and increased Csf1r expression.
Volume: 124
Issue: 5
Pages: 1122-32
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Publication
34983562 | J:318729
First Author: Bedolla A
Year: 2022
Journal: J Neuroinflammation
Title: Diphtheria toxin induced but not CSF1R inhibitor mediated microglia ablation model leads to the loss of CSF/ventricular spaces in vivo that is independent of cytokine upregulation.
Volume: 19
Issue: 1
Pages: 3
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Publication
29490706 | J:351786
First Author: Sosna J
Year: 2018
Journal: Mol Neurodegener
Title: Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
Volume: 13
Issue: 1
Pages: 11
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DO Term
DOID:0080523 | adult-onset leukoencephalopathy with axonal spheroids and pigmented glia
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Publication
17360941 | -
First Author: Gu TL
Year: 2007
Journal: Blood
Title: A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.
Volume: 110
Issue: 1
Pages: 323-33
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Publication
36517604 | J:338038
First Author: McNamara NB
Year: 2023
Journal: Nature
Title: Microglia regulate central nervous system myelin growth and integrity.
Volume: 613
Issue: 7942
Pages: 120-129
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Allele
Csf1r<em2(icre)Smoc> | MGI:7289164
Name: colony stimulating factor 1 receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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DO Term
DOID:0070343 | CSF1R-related brain malformation and osteopetrosis
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Regulatory Region
MGI:7431466 | Rr347
Type: enhancer
Organism: mouse, laboratory
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Strain
MGI:6354705 | C57BL/6JSmoc-Csf1r<em2(icre)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Csf1r<em3(CSF1R)Smoc> | MGI:7289165
Name: colony stimulating factor 1 receptor; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Csf1r<em4Smoc> | MGI:7289166
Name: colony stimulating factor 1 receptor; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tg(Csf1r-tax)3470Yiw | MGI:7517111
Name: transgene insertion 3470, Yoichiro Iwakura
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rr347<em1Prdns> | MGI:7431475
Name: regulatory region 347; endonuclease-mediated mutation 1, Clare Pridans
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Csf1r<em1Smoc> | MGI:7289163
Name: colony stimulating factor 1 receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6146045 | C3H/HeN-Tg(Csf1r-tax)3470Yiw/YiwRbrc
Attribute String: mutant strain, coisogenic, transgenic
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HT Experiment
GSE192601 | Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence [RNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE192600 | Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence [scRNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Csf1r-cre/Esr1*)1Jwp | MGI:5433683
Name: transgene insertion 1, Jeffrey W Pollard
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Csf1r-cre)1Mnz | MGI:5763756
Name: transgene insertion 1, Michel C Nussenzweig
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:7432713 | C57BL/6J-Rr347<em1Prdns>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7432688 | CBA/Ca-Rr347<em1Prdns>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6428486 | C57BL/6JSmoc-Csf1r<em3(CSF1R)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6428485 | C57BL/6JSmoc-Csf1r<em4Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Csf1r-rtTA)77Cyan | MGI:7663944
Name: transgene insertion 77, Cong Yan
Allele Type: Transgenic
Attribute String: Transactivator
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Genotype
Genotype
Symbol: Rr347/Rr347
Background: CBA/Ca-Rr347
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr347/Rr347
Background: C57BL/6J-Rr347
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE188989 | Cortical diurnal rhythms remain intact with microglial depletion
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
17971498 | J:131223
First Author: Ovchinnikov DA
Year: 2008
Journal: J Leukoc Biol
Title: Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice.
Volume: 83
Issue: 2
Pages: 430-3
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Publication
7683918 | -
First Author: Bourette RP
Year: 1993
Journal: Blood
Title: Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential.
Volume: 81
Issue: 10
Pages: 2511-20
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Publication
6582485 | -
First Author: Hampe A
Year: 1984
Journal: Proc Natl Acad Sci U S A
Title: Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
Volume: 81
Issue: 1
Pages: 85-9
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Publication
14709771 | -
First Author: Sapi E
Year: 2004
Journal: Exp Biol Med (Maywood)
Title: The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update.
Volume: 229
Issue: 1
Pages: 1-11
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Publication
22197934 | -
First Author: Rademakers R
Year: 2011
Journal: Nat Genet
Title: Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.
Volume: 44
Issue: 2
Pages: 200-5
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Publication
2849512 | -
First Author: Woolford J
Year: 1988
Journal: Cell
Title: Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype.
Volume: 55
Issue: 6
Pages: 965-77
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Publication
1834054 | -
 
First Author: Tamura T
Year: 1991
Journal: Behring Inst Mitt
Title: Transforming mechanism of the feline sarcoma virus encoded v-fms oncogene product.
Issue: 89
Pages: 93-9
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Publication
2843495 | -
 
First Author: Rettenmier CW
Year: 1986
Journal: Princess Takamatsu Symp
Title: Requirements for transformation by the fms oncogene product (CSF-1 receptor).
Volume: 17
Pages: 211-8
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Protein Domain
IPR030658 | CSF-1_receptor
Type: Family
Description: This entry represents a macrophage colony-stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR) or CD115 (Cluster of Differentiation 115). CSF1R is a tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes []. CSF-1 and CSF-1R play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis []. Mutations in the CSF1R gene cause hereditary diffuse leukoencephalopathy with spheroids, which is an autosomal-dominant central nervous system white-matter disease with variable clinical presentations, including personality and behavioral changes, dementia, depression, parkinsonism, seizures and other phenotypes [].This entry also includes the tyrosine-protein kinase transforming protein v-fms from Feline sarcoma virus. CSF1R (the c-fms product) is its cellular counterpart. It differs in some amino acid substitutions and the replacement of 50 C-terminal amino acids by 11 unrelated residues in v-fms [, , ]. v-fms can bind CSF-1 and has constitutive tyrosine-specific protein kinase activity, providing growth stimulatory signals in the absence of ligand [].
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Strain
MGI:5441529 | FVB-Tg(Csf1r-cre/Esr1*)1Jwp/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
26269531 | J:224911
First Author: Hughes R
Year: 2015
Journal: Cancer Res
Title: Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
Volume: 75
Issue: 17
Pages: 3479-91
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Strain
MGI:5776616 | C57BL/6-Tg(Csf1r-cre)1Mnz/J
Attribute String: transgenic, coisogenic, mutant strain
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Strain
MGI:7718018 | C57BL/6JSmoc-Csf1<tm2(CSF1)Smoc> Csf1r<em3(CSF1R)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6475062 | C57BL/6JSmoc-Csf1r<tm1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
10072546 | J:332067
First Author: Habu K
Year: 1999
Journal: J Immunol
Title: The human T cell leukemia virus type I-tax gene is responsible for the development of both inflammatory polyarthropathy resembling rheumatoid arthritis and noninflammatory ankylotic arthropathy in transgenic mice.
Volume: 162
Issue: 5
Pages: 2956-63
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