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Search results 601 to 644 out of 644 for Cyp1a1

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Type

Details

Score

Strain

MGI:3721798 | B6.Cg-Cyp1a<tm1Dwn> Tg(CYP1A1,CYP1A2)1Dwn

Attribute String:

congenic, mutant strain, targeted mutation, transgenic, deletion

•

Publication

27664423 | J:257718

First Author:	Chen JX
Year:	2017
Journal:	Toxicol Sci
Title:	From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells.
Volume:	155
Issue:	1
Pages:	224-233

•

Publication

22581815 | J:231719

First Author:	Li G
Year:	2012
Journal:	Cancer Prev Res (Phila)
Title:	Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
Volume:	5
Issue:	7
Pages:	963-72

•

Publication

23446353 | J:194841

First Author:	Buczacki SJ
Year:	2013
Journal:	Nature
Title:	Intestinal label-retaining cells are secretory precursors expressing Lgr5.
Volume:	495
Issue:	7439
Pages:	65-9

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Genotype

Symbol:	Cyp1a/Cyp1a Tg(CYP1A1,CYP1A2)1Dwn/Tg(CYP1A1,CYP1A2)1Dwn
Background:	B6.Cg-Cyp1a Tg(CYP1A1,CYP1A2)1Dwn
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

14575644 | J:126200

First Author:	Huang P
Year:	2003
Journal:	Toxicol Appl Pharmacol
Title:	TCDD-induced expression of Ah receptor responsive genes in the pituitary and brain of cellular retinol-binding protein (CRBP-I) knockout mice.
Volume:	192
Issue:	3
Pages:	262-74

•

Publication

9367523 | J:44195

First Author:	Savas U
Year:	1997
Journal:	Arch Biochem Biophys
Title:	Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1.
Volume:	347
Issue:	2
Pages:	181-92

•

Publication

7955076 | J:21044

First Author:	Liu RM
Year:	1994
Journal:	Carcinogenesis
Title:	Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines.
Volume:	15
Issue:	10
Pages:	2347-52

•

Publication

9264552 | J:42264

First Author:	Roy NK
Year:	1997
Journal:	Arch Biochem Biophys
Title:	Characterization of the aromatic hydrocarbon receptor gene and its expression in Atlantic tomcod.
Volume:	344
Issue:	2
Pages:	373-86

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Publication

9478971 | J:46269

First Author:	Zhang L
Year:	1998
Journal:	J Biol Chem
Title:	Characterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression.
Volume:	273
Issue:	9
Pages:	5174-83

•

Publication

9514655 | J:46615

First Author:	Vogel C
Year:	1998
Journal:	Arch Biochem Biophys
Title:	Modulation of prostaglandin H synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice.
Volume:	351
Issue:	2
Pages:	265-71

•

Publication

27638959 | J:237369

First Author:	Takahashi S
Year:	2016
Journal:	J Lipid Res
Title:	Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans.
Volume:	57
Issue:	12
Pages:	2130-2137

•

Publication

18455124 | J:134772

First Author:	Petrova TV
Year:	2008
Journal:	Cancer Cell
Title:	Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.
Volume:	13
Issue:	5
Pages:	407-19

•

Publication

24035355 | J:202689

First Author:	Kozar S
Year:	2013
Journal:	Cell Stem Cell
Title:	Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.
Volume:	13
Issue:	5
Pages:	626-33

•

Publication

28716720 | J:316020

First Author:	Joosten SPJ
Year:	2017
Journal:	Gastroenterology
Title:	MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
Volume:	153
Issue:	4
Pages:	1040-1053.e4

•

Publication

20729907 | J:166564

First Author:	Radulescu S
Year:	2010
Journal:	Oncogene
Title:	Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.
Volume:	29
Issue:	49
Pages:	6418-27

•

Publication

24788409 | J:211668

First Author:	Cordero JB
Year:	2014
Journal:	EMBO J
Title:	c-Src drives intestinal regeneration and transformation.
Volume:	33
Issue:	13
Pages:	1474-91

•

Publication

39169259 | J:358047

First Author:	Herms A
Year:	2024
Journal:	Nat Genet
Title:	Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus.
Volume:	56
Issue:	10
Pages:	2144-2157

•

Publication

19011632 | J:143082

First Author:	Marsh V
Year:	2008
Journal:	Nat Genet
Title:	Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.
Volume:	40
Issue:	12
Pages:	1436-44

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Publication

26240067 | J:226570

First Author:	Huels DJ
Year:	2015
Journal:	EMBO J
Title:	E-cadherin can limit the transforming properties of activating β-catenin mutations.
Volume:	34
Issue:	18
Pages:	2321-33

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Publication

28003334 | J:277034

First Author:	Myant KB
Year:	2017
Journal:	EMBO Mol Med
Title:	HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Volume:	9
Issue:	2
Pages:	181-197

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Publication

20818428 | J:164579

First Author:	Ahmad I
Year:	2011
Journal:	Oncogene
Title:	β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.
Volume:	30
Issue:	2
Pages:	178-89

•

Publication

20976827 | J:294141

First Author:	Cole AM
Year:	2010
Journal:	EMBO Mol Med
Title:	p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.
Volume:	2
Issue:	11
Pages:	472-86

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Publication

29891559 | J:272574

First Author:	Cai J
Year:	2018
Journal:	Genes Dev
Title:	A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease.
Volume:	32
Issue:	11-12
Pages:	781-793

•

Publication

15247325 | J:143936

First Author:	Kemp R
Year:	2004
Journal:	Nucleic Acids Res
Title:	Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity.
Volume:	32
Issue:	11
Pages:	e92

•

Publication

27548914 | J:320951

First Author:	Frede J
Year:	2016
Journal:	Nat Cell Biol
Title:	A single dividing cell population with imbalanced fate drives oesophageal tumour growth.
Volume:	18
Issue:	9
Pages:	967-78

•

Publication

28768191 | J:254518

First Author:	Asano J
Year:	2017
Journal:	Cell Rep
Title:	Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration.
Volume:	20
Issue:	5
Pages:	1050-1060

•

Publication

32424351 | J:320885

First Author:	Colom B
Year:	2020
Journal:	Nat Genet
Title:	Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Volume:	52
Issue:	6
Pages:	604-614

•

Publication

34646013 | J:325772

First Author:	Colom B
Year:	2021
Journal:	Nature
Title:	Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Volume:	598
Issue:	7881
Pages:	510-514

•

Strain

MGI:6405110 | B6.Cg-Nr1i3<tm1(NR1I3)Arte> Cyp3a13<tm1Nki> Cyp3a<tm1109(CYP3A4,CYP3A7)Arte> Cyp1a2<tm2024.1(CYP1A2)Arte> Cyp1a1<tm2025.1(CYP1A1)Arte> Cyp2d<tm1836.1(CYP2D6_i2)Arte> Nr1i2<tm1(NR1I2)Arte> Cyp2c<tm1897.1(Alb-CYP2C9)Arte>/Tac

Attribute String:

targeted mutation, mutant strain

•

Publication

35383166 | J:325748

First Author:	Shah K
Year:	2022
Journal:	Nat Commun
Title:	Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells.
Volume:	13
Issue:	1
Pages:	1827

•

Publication

21727895 | J:174842

First Author:	de Lau W
Year:	2011
Journal:	Nature
Title:	Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
Volume:	476
Issue:	7360
Pages:	293-7

•

Publication

21113151 | J:168728

First Author:	Sato T
Year:	2011
Journal:	Nature
Title:	Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.
Volume:	469
Issue:	7330
Pages:	415-8

•

Publication

26989177 | J:235531

First Author:	Elbediwy A
Year:	2016
Journal:	Development
Title:	Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Volume:	143
Issue:	10
Pages:	1674-87

•

Publication

38039966 | J:354472

First Author:	Brockmann L
Year:	2023
Journal:	Immunity
Title:	Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10.
Volume:	56
Issue:	12
Pages:	2719-2735.e7

•

Publication

19657387 | J:152479

First Author:	Davies PS
Year:	2009
Journal:	PLoS One
Title:	Inflammation and proliferation act together to mediate intestinal cell fusion.
Volume:	4
Issue:	8
Pages:	e6530

•

Publication

22665058 | J:197230

First Author:	Radulescu S
Year:	2013
Journal:	Oncogene
Title:	Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation.
Volume:	32
Issue:	16
Pages:	2048-57

•

Publication

23665120 | J:198485

First Author:	Myant KB
Year:	2013
Journal:	Cell Stem Cell
Title:	ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Volume:	12
Issue:	6
Pages:	761-73

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Publication

29556067 | J:260740

First Author:	Huels DJ
Year:	2018
Journal:	Nat Commun
Title:	Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.
Volume:	9
Issue:	1
Pages:	1132

•

Publication

27060105 | J:239484

First Author:	Zhang Y
Year:	2016
Journal:	Biochem J
Title:	Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity.
Volume:	473
Issue:	8
Pages:	961-1000

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Publication

29967292 | J:272584

First Author:	Okano-Uchida T
Year:	2018
Journal:	Genes Dev
Title:	Endoreduplication of the mouse genome in the absence of ORC1.
Volume:	32
Issue:	13-14
Pages:	978-990

•

Strain

MGI:3818514 | B6.Cg-Cyp1<tm1Dwn> Ahr<d> Tg(CYP1A1,CYP1A2)1Dwn/DwnJ

Attribute String:

transgenic, spontaneous mutation, congenic, deletion, targeted mutation

•

Publication

39313617 | J:354890

First Author:	Herms A
Year:	2024
Journal:	Nat Genet
Title:	Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium.

•

Publication

25533675 | J:219292

First Author:	Kobayashi T
Year:	2015
Journal:	Nat Rev Cancer
Title:	Modelling bladder cancer in mice: opportunities and challenges.
Volume:	15
Issue:	1
Pages:	42-54

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