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Search results 601 to 653 out of 653 for Dsp

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Type Details Score
DO Term
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Publication  
First Author: Queiroz AL
Year: 2021
Journal: Mol Metab
Title: The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1? inhibition.
Volume: 51
Pages: 101226
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Allele
Name: transgene insertion JIL399, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Publication
First Author: Wang L
Year: 2020
Journal: Cell
Title: A MicroRNA Linking Human Positive Selection and Metabolic Disorders.
Volume: 183
Issue: 3
Pages: 684-701.e14
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Strain
Attribute String: mutant stock, transgenic
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Publication
First Author: Tanaka H
Year: 2003
Journal: Peptides
Title: Insect diapause-specific peptide from the leaf beetle has consensus with a putative iridovirus peptide.
Volume: 24
Issue: 9
Pages: 1327-33
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Publication
First Author: Kouno T
Year: 2007
Journal: Biochemistry
Title: The structure of a novel insect peptide explains its Ca2+ channel blocking and antifungal activities.
Volume: 46
Issue: 48
Pages: 13733-41
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Protein Domain
Type: Homologous_superfamily
Description: This superfamily consists of diapausin-related antimicrobial peptides. Diapause during periods of environmental adversity is an essential part of the life cycle of many organisms, with the molecular basis being different among animals. Diapause-specific peptides (DSP) provide anti-fungal activity and act as N-type voltage-gated calcium channel blocker []. The overall structure of DSP is compact due to the three disulfide bridges that indicate a high similarity with insect- and plant-derived antifungal peptides.
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Publication
First Author: Meekins DA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Phosphoglucan-bound structure of starch phosphatase Starch Excess4 reveals the mechanism for C6 specificity.
Volume: 111
Issue: 20
Pages: 7272-7
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Publication
First Author: Ganesh S
Year: 2002
Journal: Hum Mol Genet
Title: Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: exon 1 mutations associate with an early-onset cognitive deficit subphenotype.
Volume: 11
Issue: 11
Pages: 1263-71
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Protein Domain
Type: Domain
Description: Proteins containing this domain include vertebrate dual specificity protein phosphatase Laforin and plant starch excess4 (SEX4).Laforin (encoded by the EPM2A gene) is a dual-specificity phosphatase that dephosphorylates complex carbohydrates. Mutations in the EPM2A gene cause Lafora disease (LD), a fatal autosomal recessive neurodegenerative disorder characterised by the presence of progressive neurological deterioration, myoclonus, and epilepsy []. Pathologically, LD is characterised by distinctive polyglucosans, which are formations of abnormal glycogen []. Laforin prevents LD by at least two mechanisms: by preventing hyperphosphorylation of glycogen by dephosphorylating it, allowing proper glycogen formation, and by promoting the ubiquitination of proteins involved in glycogen metabolism via its interaction with malin. Laforin contains an N-terminal CBM20 (carbohydrate-binding module, family 20) domain and a C-terminal catalytic dual specificity phosphatase (DSP) domain [].Plant SEX4 (also known as DSP4) regulates starch metabolism by selectively dephosphorylating glucose moieties within starch glucan chains. It contains an N-terminal catalytic DSP domain and a C-terminal Early (E) set domain [].
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HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
First Author: Ritchie HH
Year: 1996
Journal: Arch Oral Biol
Title: Partial cDNA sequencing of mouse dentine sialoprotein and detection of its specific expression by odontoblasts.
Volume: 41
Issue: 6
Pages: 571-5
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Publication
First Author: Koralov SB
Year: 2008
Journal: Cell
Title: Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage.
Volume: 132
Issue: 5
Pages: 860-74
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Publication
First Author: Zhang L
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Successful co-immunoprecipitation of Oct4 and Nanog using cross-linking.
Volume: 361
Issue: 3
Pages: 611-4
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Publication
First Author: Raththagala M
Year: 2015
Journal: Mol Cell
Title: Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.
Volume: 57
Issue: 2
Pages: 261-72
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Publication
First Author: Nakamura K
Year: 1999
Journal: Biochem J
Title: Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis.
Volume: 344 Pt 3
Issue: Pt 3
Pages: 819-25
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Publication
First Author: Lara NLM
Year: 2017
Journal: Reproduction
Title: Neonatal hypothyroidism does not increase Sertoli cell proliferation in iNOS(-/-) mice.
Volume: 154
Issue: 1
Pages: 13-22
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Publication
First Author: Lombardi R
Year: 2011
Journal: Circ Res
Title: Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy.
Volume: 109
Issue: 12
Pages: 1342-53
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Publication  
First Author: Yuan G
Year: 2017
Journal: Sci Rep
Title: Dentin Sialoprotein is a Novel Substrate of Matrix Metalloproteinase 9 in vitro and in vivo.
Volume: 7
Pages: 42449
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Publication
First Author: Bhushan R
Year: 2019
Journal: J Cell Mol Med
Title: An integrative systems approach identifies novel candidates in Marfan syndrome-related pathophysiology.
Volume: 23
Issue: 4
Pages: 2526-2535
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Publication
First Author: Goldberg M
Year: 2011
Journal: Cells Tissues Organs
Title: Differential effects of fibromodulin deficiency on mouse mandibular bones and teeth: a micro-CT time course study.
Volume: 194
Issue: 2-4
Pages: 205-10
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Publication
First Author: Goldberg M
Year: 2006
Journal: J Histochem Cytochem
Title: Fibromodulin-deficient mice display impaired collagen fibrillogenesis in predentin as well as altered dentin mineralization and enamel formation.
Volume: 54
Issue: 5
Pages: 525-37
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Publication
First Author: Lim WH
Year: 2014
Journal: J Bone Miner Res
Title: Wnt signaling regulates pulp volume and dentin thickness.
Volume: 29
Issue: 4
Pages: 892-901
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Publication
First Author: Suzuki S
Year: 2009
Journal: Matrix Biol
Title: Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization.
Volume: 28
Issue: 4
Pages: 221-9
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Publication
First Author: Gibson MP
Year: 2013
Journal: Eur J Oral Sci
Title: Role of the NH2 -terminal fragment of dentin sialophosphoprotein in dentinogenesis.
Volume: 121
Issue: 2
Pages: 76-85
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Publication
First Author: Yang G
Year: 2017
Journal: Sci Rep
Title: BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts.
Volume: 7
Issue: 1
Pages: 10775
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Publication
First Author: Shi P
Year: 2023
Journal: Oral Dis
Title: Activation of Wnt signaling in Axin2(+) cells leads to osteodentin formation and cementum overgrowth.
Volume: 29
Issue: 8
Pages: 3551-3558
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Publication  
First Author: Jamal T
Year: 2024
Journal: Prog Neurobiol
Title: Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex.
Volume: 239
Pages: 102630
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Publication  
First Author: Seo H
Year: 2026
Journal: Nat Commun
Title: Dual platform spatial transcriptomics reveals parvalbumin interneuron subtype vulnerability in mouse models of Alzheimer's disease.
Volume: 17
Issue: 1
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Publication
First Author: White SN
Year: 2007
Journal: J Biol Chem
Title: Ectopic expression of dentin sialoprotein during amelogenesis hardens bulk enamel.
Volume: 282
Issue: 8
Pages: 5340-5
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Publication
First Author: Napierala D
Year: 2012
Journal: J Bone Miner Res
Title: Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice.
Volume: 27
Issue: 8
Pages: 1735-45
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Publication
First Author: Chen AJ
Year: 2002
Journal: J Biol Chem
Title: The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway.
Volume: 277
Issue: 39
Pages: 36592-601
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Publication
First Author: B?gue-Kirn C
Year: 1998
Journal: Eur J Oral Sci
Title: Dentin sialoprotein, dentin phosphoprotein, enamelysin and ameloblastin: tooth-specific molecules that are distinctively expressed during murine dental differentiation.
Volume: 106
Issue: 5
Pages: 963-70
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Publication
First Author: Narayanan K
Year: 2004
Journal: J Biol Chem
Title: The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation.
Volume: 279
Issue: 44
Pages: 45423-32
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Publication
First Author: Tornberg UC
Year: 1995
Journal: EMBO J
Title: B-1a, B-1b and B-2 B cells display unique VHDJH repertoires formed at different stages of ontogeny and under different selection pressures.
Volume: 14
Issue: 8
Pages: 1680-9
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Publication
First Author: D'Souza RN
Year: 1997
Journal: J Bone Miner Res
Title: Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo.
Volume: 12
Issue: 12
Pages: 2040-9
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Publication
First Author: Rom?-Mateo C
Year: 2007
Journal: J Mol Biol
Title: A novel phosphatase family, structurally related to dual-specificity phosphatases, that displays unique amino acid sequence and substrate specificity.
Volume: 374
Issue: 4
Pages: 899-909
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Publication
First Author: Hagihara H
Year: 2018
Journal: Mol Brain
Title: Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant ?-synuclein.
Volume: 11
Issue: 1
Pages: 38
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Publication
First Author: Li W
Year: 2017
Journal: Sci Rep
Title: Dentin sialoprotein facilitates dental mesenchymal cell differentiation and dentin formation.
Volume: 7
Issue: 1
Pages: 300
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Publication
First Author: Xu X
Year: 2025
Journal: J Biol Chem
Title: Dentin sialoprotein acts as an angiogenic factor through association with the membrane receptor endoglin.
Volume: 301
Issue: 3
Pages: 108279
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Publication
First Author: Aoki N
Year: 2001
Journal: J Biochem
Title: A growing family of dual specificity phosphatases with low molecular masses.
Volume: 130
Issue: 1
Pages: 133-40
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Publication
First Author: Auharek SA
Year: 2011
Journal: Int J Androl
Title: Sertoli cell numbers and spermatogenic efficiency are increased in inducible nitric oxide synthase mutant mice.
Volume: 34
Issue: 6 Pt 2
Pages: e621-9
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Publication  
First Author: Webber CA
Year: 2013
Journal: Neuroscience
Title: Nerve growth factor acts through the TrkA receptor to protect sensory neurons from the damaging effects of the HIV-1 viral protein, Vpr.
Volume: 252
Pages: 512-25
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Publication
First Author: Holsberger DR
Year: 2005
Journal: Biol Reprod
Title: Cell-cycle inhibitors p27Kip1 and p21Cip1 regulate murine Sertoli cell proliferation.
Volume: 72
Issue: 6
Pages: 1429-36
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Publication
First Author: Zhang X
Year: 2019
Journal: J Mol Histol
Title: Distinctive role of ACVR1 in dentin formation: requirement for dentin thickness in molars and prevention of osteodentin formation in incisors of mice.
Volume: 50
Issue: 1
Pages: 43-61
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Publication
First Author: Kenchegowda D
Year: 2012
Journal: PLoS One
Title: Critical role of Klf5 in regulating gene expression during post-eyelid opening maturation of mouse corneas.
Volume: 7
Issue: 9
Pages: e44771
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Publication  
First Author: Elling CL
Year: 2024
Journal: Int J Pediatr Otorhinolaryngol
Title: The A2ml1-Knockout mouse as an animal model for non-syndromic otitis media.
Volume: 181
Pages: 111980
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Publication
First Author: Qin C
Year: 2001
Journal: J Biol Chem
Title: Identification and characterization of the carboxyl-terminal region of rat dentin sialoprotein.
Volume: 276
Issue: 2
Pages: 904-9
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Publication
First Author: Wang Y
Year: 2020
Journal: Circulation
Title: Integrin ?1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy.
Volume: 141
Issue: 18
Pages: 1477-1493
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Publication
First Author: Xu C
Year: 2023
Journal: Int Endod J
Title: Axin2-CreERT2 mediated knockout of bone morphogenetic protein receptor type 1A caused abnormal secondary dentine and altered cell fate of Axin2-expressing odontogenic cells.
Volume: 56
Issue: 8
Pages: 1000-1010
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Protein
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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