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Search results 601 to 700 out of 9662 for Egf

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
616459 | MEGF6
Type: gene
Organism: cattle
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Gene
781765 | EGFL6
Type: gene
Organism: cattle
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Gene
782820 | EGFL8
Type: gene
Organism: cattle
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Gene
100336680 | MEGF11
Type: gene
Organism: cattle
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Gene
100610750 | MEGF8
Type: gene
Organism: chimpanzee
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Gene
100613248 | EGFL8
Type: gene
Organism: chimpanzee
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Gene
415545 | MEGF11
Type: gene
Organism: chicken
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Gene
417137 | EGFL7
Type: gene
Organism: chicken
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Gene
418637 | EGFL6
Type: gene
Organism: chicken
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Gene
419385 | MEGF6
Type: gene
Organism: chicken
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Gene
424786 | DNER
Type: gene
Organism: chicken
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Gene
427126 | MEGF10
Type: gene
Organism: chicken
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Gene
697150 | MEGF6
Type: gene
Organism: macaque, rhesus
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Gene
703899 | MEGF10
Type: gene
Organism: macaque, rhesus
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Gene
704605 | MEGF9
Type: gene
Organism: macaque, rhesus
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Gene
709352 | MEGF8
Type: gene
Organism: macaque, rhesus
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Gene
709840 | EGFL7
Type: gene
Organism: macaque, rhesus
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Gene
710384 | DNER
Type: gene
Organism: macaque, rhesus
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Gene
711280 | EGFL6
Type: gene
Organism: macaque, rhesus
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Gene
714198 | MEGF11
Type: gene
Organism: macaque, rhesus
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Gene
717145 | EGFL8
Type: gene
Organism: macaque, rhesus
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Gene
779617 | dner
Type: gene
Organism: frog, western clawed
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Gene
779640 | egfl8
Type: gene
Organism: frog, western clawed
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Gene
780183 | megf10
Type: gene
Organism: frog, western clawed
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Gene
780371 | egfl7
Type: gene
Organism: frog, western clawed
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Publication
22975374 | J:190126
First Author: Ardito CM
Year: 2012
Journal: Cancer Cell
Title: EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Volume: 22
Issue: 3
Pages: 304-17
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Publication
25594178 | J:227368
First Author: Tan X
Year: 2015
Journal: Cell
Title: A kinase-independent role for EGF receptor in autophagy initiation.
Volume: 160
Issue: 1-2
Pages: 145-60
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Protein Coding Gene
MGI:1858235 | Celsr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1858236 | Celsr3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31060902 | J:277617
 
First Author: Ballester-López C
Year: 2019
Journal: EBioMedicine
Title: The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease.
Volume: 43
Pages: 562-575
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Publication
16877529 | J:129734
First Author: Chansel D
Year: 2006
Journal: FASEB J
Title: Heparin binding EGF is necessary for vasospastic response to endothelin.
Volume: 20
Issue: 11
Pages: 1936-8
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Publication
17556541 | J:122380
First Author: Zhang YW
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.
Volume: 104
Issue: 25
Pages: 10613-8
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Publication
17940036 | J:125912
First Author: Natarajan A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The EGF receptor is required for efficient liver regeneration.
Volume: 104
Issue: 43
Pages: 17081-6
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Protein Domain
IPR026823 | cEGF
Type: Domain
Description: cEGF, or complement Clr-like EGF, domains have six conserved cysteine residues disulfide-bonded into the characteristic pattern 'ababcc'. They are found in blood coagulation proteins such as fibrillin, Clr and Cls, thrombomodulin, and the LDL receptor. The core fold of the EGF domain consists of two small β-hairpins packed against each other. Two major structural variants have been identified based on the structural context of the C-terminal cysteine residue of disulfide 'c' in the C-terminal hairpin: hEGFs and cEGFs []. In cEGFs the C-terminal thiol resides on the C-terminal β-sheet, resulting in long loop-lengths between the cysteine residues of disulfide 'c', typically C[10+]XC. These longer loop-lengths may have arisen by selective cysteine loss from a four-disulfide EGF template such as laminin or integrin. Tandem cEGF domains have five linking residues between terminal cysteines of adjacent domains. cEGF domains may or may not bind calcium in the linker region. cEGF domains with the consensus motif CXN4X[F,Y]XCXC are hydroxylated exclusively on the asparagine residue.
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Protein
D3Z459
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Protein
D3Z5Q3
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Protein
D3Z052
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: false
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Protein
A0A0N4SVY8
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
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Protein
D3YWW8
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Publication
17182860 | J:123889
First Author: Shen F
Year: 2007
Journal: Mol Biol Cell
Title: Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.
Volume: 18
Issue: 3
Pages: 732-42
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Publication
23125191 | J:194123
First Author: Sukhanova A
Year: 2013
Journal: Cancer Discov
Title: Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Volume: 3
Issue: 1
Pages: 96-111
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Publication
23720051 | J:199104
First Author: Tardáguila M
Year: 2013
Journal: Cancer Res
Title: CX3CL1 promotes breast cancer via transactivation of the EGF pathway.
Volume: 73
Issue: 14
Pages: 4461-73
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Publication
9450997 | J:45950
First Author: Sibilia M
Year: 1998
Journal: EMBO J
Title: A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor.
Volume: 17
Issue: 3
Pages: 719-31
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Protein
E5RKG1
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
A0A140LJ15
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
A0A140LJ95
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Protein
E5RKG0
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Publication
10943841 | J:63426
First Author: Sibilia M
Year: 2000
Journal: Cell
Title: The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.
Volume: 102
Issue: 2
Pages: 211-20
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Publication
23416450 | J:197463
First Author: Puehringer D
Year: 2013
Journal: Nat Neurosci
Title: EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons.
Volume: 16
Issue: 4
Pages: 407-15
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Publication
22975375 | J:192907
First Author: Navas C
Year: 2012
Journal: Cancer Cell
Title: EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 3
Pages: 318-30
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Publication
23846654 | J:204749
First Author: Zheng Y
Year: 2013
Journal: Nature
Title: Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
Volume: 499
Issue: 7457
Pages: 166-71
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Publication
20398727 | J:168386
First Author: Liebmann C
Year: 2011
Journal: Mol Cell Endocrinol
Title: EGF receptor activation by GPCRs: an universal pathway reveals different versions.
Volume: 331
Issue: 2
Pages: 222-31
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Protein Coding Gene
MGI:1100883 | Celsr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2445053 | Ccbe1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9205141 | J:41158
First Author: Miettinen PJ
Year: 1997
Journal: Dev Biol
Title: Impaired lung branching morphogenesis in the absence of functional EGF receptor.
Volume: 186
Issue: 2
Pages: 224-36
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Publication
26876200 | J:230814
First Author: Fabris L
Year: 2016
Journal: Oncogene
Title: Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.
Volume: 35
Issue: 37
Pages: 4914-26
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Publication
24631292 | J:211995
First Author: Lee HL
Year: 2014
Journal: Exp Cell Res
Title: Smurf1 plays a role in EGF inhibition of BMP2-induced osteogenic differentiation.
Volume: 323
Issue: 2
Pages: 276-87
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Publication
11900977 | J:76231
First Author: Jászai J
Year: 2002
Journal: Mech Dev
Title: Cloning and expression of Ventrhoid, a novel vertebrate homologue of the Drosophila EGF pathway gene rhomboid.
Volume: 113
Issue: 1
Pages: 73-7
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Publication
37223028 | J:337239
 
First Author: Ruiz-Otero N
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis.
Volume: 14
Pages: 1161085
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Publication
22357850 | J:182359
First Author: Fricker M
Year: 2012
Journal: J Neurosci
Title: MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.
Volume: 32
Issue: 8
Pages: 2657-66
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Publication
7618085 | J:26834
First Author: Sibilia M
Year: 1995
Journal: Science
Title: Strain-dependent epithelial defects in mice lacking the EGF receptor.
Volume: 269
Issue: 5221
Pages: 234-8
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Publication
10673385 | J:60172
First Author: Keegan BP
Year: 2000
Journal: Biochem Biophys Res Commun
Title: The internalization and endosomal trafficking of the EGF receptor in response to EGF is delayed in the waved-2 mouse liver.
Volume: 267
Issue: 3
Pages: 881-6
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Protein
A0A0A6YW76
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: true
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Publication
2030916 | J:27178
First Author: Avivi A
Year: 1991
Journal: Oncogene
Title: Comparison of EGF receptor sequences as a guide to study the ligand binding site.
Volume: 6
Issue: 4
Pages: 673-6
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Publication
18757723 | J:162987
First Author: Ding W
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.
Volume: 105
Issue: 36
Pages: 13433-8
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Publication
15383614 | J:335497
First Author: de Melker AA
Year: 2004
Journal: J Cell Sci
Title: c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.
Volume: 117
Issue: Pt 21
Pages: 5001-12
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Publication
22411794 | J:182221
First Author: Wang Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1.
Volume: 109
Issue: 13
Pages: 4892-7
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Publication
24063894 | J:205059
First Author: Cho J
Year: 2013
Journal: Cancer Res
Title: Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization.
Volume: 73
Issue: 22
Pages: 6770-9
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Publication
26280537 | J:227353
First Author: Zheng Y
Year: 2015
Journal: Nat Cell Biol
Title: Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation.
Volume: 17
Issue: 10
Pages: 1348-55
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Publication
11738740 | -
First Author: Hisaeda H
Year: 2001
Journal: Vaccine
Title: Antibodies to Plasmodium vivax transmission-blocking vaccine candidate antigens Pvs25 and Pvs28 do not show synergism.
Volume: 20
Issue: 5-6
Pages: 763-70
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Publication
16327807 | -
First Author: Saxena AK
Year: 2006
Journal: Nat Struct Mol Biol
Title: The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms.
Volume: 13
Issue: 1
Pages: 90-1
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Protein Domain
IPR010423 | Pvs25/Psv28_EGF
Type: Domain
Description: Pvs25 and Pvs28 are expressed on the surface of ookinetes from several species of Plasmodium. These proteins are potential candidates for vaccine and induce antibodies that block the infectivity of Plasmodium vivax in immunised animals []. The structure of these protein shows they are composed of four EGF domains [].
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Publication
35096831 | J:326680
 
First Author: Ren Y
Year: 2021
Journal: Front Cell Dev Biol
Title: MFG-E8 Maintains Cellular Homeostasis by Suppressing Endoplasmic Reticulum Stress in Pancreatic Exocrine Acinar Cells.
Volume: 9
Pages: 803876
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Publication
19812188 | J:156628
First Author: Miksa M
Year: 2009
Journal: J Immunol
Title: Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII [corrected].
Volume: 183
Issue: 9
Pages: 5983-90
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Publication
25006249 | J:325170
First Author: Soki FN
Year: 2014
Journal: J Biol Chem
Title: Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis.
Volume: 289
Issue: 35
Pages: 24560-72
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Protein
Q3MI99
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
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Publication
19240116 | J:145962
First Author: Raymond AS
Year: 2009
Journal: J Cell Sci
Title: A novel role for SED1 (MFG-E8) in maintaining the integrity of the epididymal epithelium.
Volume: 122
Issue: Pt 6
Pages: 849-58
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Publication
10393179 | J:56337
First Author: Nakashima S
Year: 1999
Journal: EMBO J
Title: Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors.
Volume: 18
Issue: 13
Pages: 3629-42
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Publication
16306133 | J:106796
First Author: Ogawa M
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Altered metaplastic response of waved-2 EGF receptor mutant mice to acute oxyntic atrophy.
Volume: 290
Issue: 4
Pages: G793-804
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Publication
20133479 | J:185851
First Author: Zhang Z
Year: 2010
Journal: J Am Soc Nephrol
Title: Targeted inactivation of EGF receptor inhibits renal collecting duct development and function.
Volume: 21
Issue: 4
Pages: 573-8
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Publication
17881575 | J:125303
First Author: Schaeper U
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Volume: 104
Issue: 39
Pages: 15376-81
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Publication
19914347 | J:164823
First Author: Shiraishi H
Year: 2010
Journal: Biochim Biophys Acta
Title: Alternative cell death of Apaf1-deficient neural progenitor cells induced by withdrawal of EGF or insulin.
Volume: 1800
Issue: 3
Pages: 405-15
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Publication
18424623 | J:136799
First Author: Hardie WD
Year: 2008
Journal: Am J Physiol Lung Cell Mol Physiol
Title: EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.
Volume: 294
Issue: 6
Pages: L1217-25
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Publication
30072422 | J:289172
First Author: Chen J
Year: 2018
Journal: J Am Soc Nephrol
Title: EGF Receptor-Dependent YAP Activation Is Important for Renal Recovery from AKI.
Volume: 29
Issue: 9
Pages: 2372-2385
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Publication
33950315 | J:310482
First Author: Düsterhöft S
Year: 2021
Journal: Cell Mol Life Sci
Title: The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Volume: 78
Issue: 11
Pages: 5015-5040
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Publication
2176151 | J:318709
First Author: Margolis B
Year: 1990
Journal: EMBO J
Title: The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.
Volume: 9
Issue: 13
Pages: 4375-80
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Publication
9049300 | J:38655
First Author: Migliaccio E
Year: 1997
Journal: EMBO J
Title: Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.
Volume: 16
Issue: 4
Pages: 706-16
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Publication
17950662 | J:130679
First Author: Bassa BV
Year: 2007
Journal: Biochim Biophys Acta
Title: Lysophosphatidylcholine stimulates EGF receptor activation and mesangial cell proliferation: regulatory role of Src and PKC.
Volume: 1771
Issue: 11
Pages: 1364-71
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Publication
18467504 | J:138674
First Author: McElroy SJ
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.
Volume: 295
Issue: 2
Pages: G285-93
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Publication
19549686 | J:153161
First Author: Grimm I
Year: 2009
Journal: J Cell Sci
Title: Coordinate pathways for nucleotide and EGF signaling in cultured adult neural progenitor cells.
Volume: 122
Issue: Pt 14
Pages: 2524-33
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Publication
10484377 | J:153269
First Author: Erwin CR
Year: 1999
Journal: Am J Physiol
Title: Intestinal overexpression of EGF in transgenic mice enhances adaptation after small bowel resection.
Volume: 277
Issue: 3 Pt 1
Pages: G533-40
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Publication
22190492 | J:317461
First Author: Macdonald-Obermann JL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging.
Volume: 109
Issue: 1
Pages: 137-42
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Publication
18701712 | J:138989
First Author: Yamaoka T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis.
Volume: 105
Issue: 33
Pages: 11772-7
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Publication
20382892 | J:162255
First Author: Su YQ
Year: 2010
Journal: Mol Endocrinol
Title: Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling.
Volume: 24
Issue: 6
Pages: 1230-9
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Publication
18985730 | J:145027
First Author: Nitta M
Year: 2009
Journal: Dev Dyn
Title: FGF alters epithelial competence for EGF at the initiation of branching morphogenesis of mouse submandibular gland.
Volume: 238
Issue: 2
Pages: 315-23
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UniProt Feature
UniProt Feature
Begin: 22
Description: von Willebrand factor C and EGF domain-containing protein
Type: chain
End: 929
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UniProt Feature
UniProt Feature
Begin: 20
Description: von Willebrand factor D and EGF domain-containing protein
Type: chain
End: 926
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Publication
26801181 | J:230819
First Author: Schuster-Gossler K
Year: 2016
Journal: Genetics
Title: Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.
Volume: 202
Issue: 3
Pages: 1119-33
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Publication
18445292 | J:136658
 
First Author: Ge C
Year: 2008
Journal: BMC Dev Biol
Title: In vivo consequences of deleting EGF repeats 8-12 including the ligand binding domain of mouse Notch1.
Volume: 8
Pages: 48
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Publication
32601248 | J:300116
First Author: Stupack J
Year: 2020
Journal: J Neurosci
Title: Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.
Volume: 40
Issue: 31
Pages: 5908-5921
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom