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Search results 601 to 700 out of 922 for Epas1

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Type Details Score
Publication
24947359 | J:230173
First Author: Choe SS
Year: 2014
Journal: Diabetes
Title: Macrophage HIF-2α ameliorates adipose tissue inflammation and insulin resistance in obesity.
Volume: 63
Issue: 10
Pages: 3359-71
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20713899 | J:178586
First Author: Chen L
Year: 2010
Journal: Circulation
Title: Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression.
Volume: 122
Issue: 9
Pages: 910-9
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Publication
31668872 | J:283696
First Author: Zhang X
Year: 2019
Journal: Cell Metab
Title: Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism.
Volume: 30
Issue: 5
Pages: 937-951.e5
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Publication
24347567 | J:206286
First Author: Yang S
Year: 2015
Journal: Ann Rheum Dis
Title: NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
Volume: 74
Issue: 3
Pages: 595-602
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Publication
37227777 | J:337824
 
First Author: Zhang J
Year: 2023
Journal: J Clin Invest
Title: Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
Volume: 133
Issue: 13
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Publication
23610397 | J:197349
First Author: Yuan G
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.
Volume: 110
Issue: 19
Pages: E1788-96
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Publication
12606578 | J:82257
First Author: Morita M
Year: 2003
Journal: EMBO J
Title: HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin.
Volume: 22
Issue: 5
Pages: 1134-46
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Publication
17284606 | J:119731
First Author: Gruber M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Acute postnatal ablation of Hif-2alpha results in anemia.
Volume: 104
Issue: 7
Pages: 2301-6
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Publication
24037341 | J:206050
First Author: Cowburn AS
Year: 2014
Journal: J Invest Dermatol
Title: Epidermal deletion of HIF-2α stimulates wound closure.
Volume: 134
Issue: 3
Pages: 801-808
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Publication
36291563 | J:333901
 
First Author: Lu X
Year: 2022
Journal: Biomolecules
Title: Pulmonary Thrombosis Promotes Tumorigenesis via Myeloid Hypoxia-Inducible Factors.
Volume: 12
Issue: 10
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Publication
34325467 | J:321683
 
First Author: DeBerge M
Year: 2021
Journal: J Exp Med
Title: Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair.
Volume: 218
Issue: 9
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Publication
34433035 | J:330772
First Author: Li X
Year: 2021
Journal: Cell Rep
Title: Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance.
Volume: 36
Issue: 8
Pages: 109607
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Publication
33202783 | J:304997
 
First Author: Kerber EL
Year: 2020
Journal: Int J Mol Sci
Title: The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease.
Volume: 21
Issue: 22
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Publication
24196071 | J:207679
First Author: Thompson AA
Year: 2014
Journal: Blood
Title: Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.
Volume: 123
Issue: 3
Pages: 366-76
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Publication
20952691 | J:168419
First Author: Eubank TD
Year: 2011
Journal: Blood
Title: Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes.
Volume: 117
Issue: 1
Pages: 323-32
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Publication
22299048 | J:184217
First Author: Schietke RE
Year: 2012
Journal: PLoS One
Title: Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.
Volume: 7
Issue: 1
Pages: e31034
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Publication
27150457 | J:253838
 
First Author: Torres-Capelli M
Year: 2016
Journal: Sci Rep
Title: Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation.
Volume: 6
Pages: 25357
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Publication
17992257 | J:130780
First Author: Hickey MM
Year: 2007
Journal: J Clin Invest
Title: von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Volume: 117
Issue: 12
Pages: 3879-89
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Publication
22295069 | J:222349
First Author: Zhang S
Year: 2012
Journal: PLoS One
Title: Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2α activation.
Volume: 7
Issue: 1
Pages: e29876
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Publication
23894152 | J:202361
First Author: Guitart AV
Year: 2013
Journal: Blood
Title: Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance.
Volume: 122
Issue: 10
Pages: 1741-5
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Publication
23777768 | J:202286
First Author: Wilkinson N
Year: 2013
Journal: Blood
Title: IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation.
Volume: 122
Issue: 9
Pages: 1658-68
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Publication
36625299 | J:339542
 
First Author: Duan LJ
Year: 2023
Journal: Biol Open
Title: Tailless and hypoxia inducible factor-2α cooperate to sustain proangiogenic states of retinal astrocytes in neonatal mice.
Volume: 12
Issue: 1
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Publication
25796140 | J:222648
 
First Author: Smeyne M
Year: 2015
Journal: Neuroscience
Title: HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta.
Volume: 295
Pages: 23-38
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Publication
24475033 | J:212719
First Author: Duan LJ
Year: 2014
Journal: PLoS One
Title: Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.
Volume: 9
Issue: 1
Pages: e84736
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Publication
33483479 | J:301258
First Author: Rudloff S
Year: 2021
Journal: Nat Commun
Title: Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress.
Volume: 12
Issue: 1
Pages: 549
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Publication
38363679 | J:350587
First Author: Farahani E
Year: 2024
Journal: Cell Rep
Title: The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation.
Volume: 43
Issue: 2
Pages: 113792
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Publication
26746864 | J:350586
First Author: Barteczek P
Year: 2017
Journal: J Cereb Blood Flow Metab
Title: Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke.
Volume: 37
Issue: 1
Pages: 291-306
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Publication
34593646 | J:311736
 
First Author: Yook JS
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis.
Volume: 118
Issue: 40
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Publication
22264788 | J:180281
First Author: Branco-Price C
Year: 2012
Journal: Cancer Cell
Title: Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success.
Volume: 21
Issue: 1
Pages: 52-65
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Publication
19454749 | J:150747
First Author: Fang HY
Year: 2009
Journal: Blood
Title: Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia.
Volume: 114
Issue: 4
Pages: 844-59
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Publication
26422241 | J:243467
First Author: Saini Y
Year: 2015
Journal: PLoS One
Title: Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice.
Volume: 10
Issue: 9
Pages: e0139270
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Publication
16971531 | J:144667
First Author: Chavez JC
Year: 2006
Journal: J Neurosci
Title: The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.
Volume: 26
Issue: 37
Pages: 9471-81
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Publication
22426208 | J:184551
First Author: Skuli N
Year: 2012
Journal: J Clin Invest
Title: Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes.
Volume: 122
Issue: 4
Pages: 1427-43
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Publication
22547685 | J:186671
First Author: Glick D
Year: 2012
Journal: Mol Cell Biol
Title: BNip3 regulates mitochondrial function and lipid metabolism in the liver.
Volume: 32
Issue: 13
Pages: 2570-84
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Publication
29343683 | J:259999
First Author: Meng X
Year: 2018
Journal: Nat Commun
Title: Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.
Volume: 9
Issue: 1
Pages: 251
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Publication
19899108 | J:161255
First Author: Shomento SH
Year: 2010
Journal: J Cell Biochem
Title: Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development.
Volume: 109
Issue: 1
Pages: 196-204
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Publication
29615467 | J:263984
 
First Author: Cristante E
Year: 2018
Journal: Development
Title: Late neuroprogenitors contribute to normal retinal vascular development in a Hif2a-dependent manner.
Volume: 145
Issue: 8
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Publication
31281892 | J:287565
First Author: Lee YS
Year: 2019
Journal: Sci Adv
Title: Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation.
Volume: 5
Issue: 7
Pages: eaaw4176
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Publication
19352007 | J:149590
First Author: Mastrogiannaki M
Year: 2009
Journal: J Clin Invest
Title: HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
Volume: 119
Issue: 5
Pages: 1159-66
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Publication
39039245 | J:352132
First Author: Lee SY
Year: 2024
Journal: Commun Biol
Title: Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis.
Volume: 7
Issue: 1
Pages: 892
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Publication
32019729 | J:317676
 
First Author: Hale AT
Year: 2020
Journal: Adv Biol Regul
Title: Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
Volume: 76
Pages: 100694
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Publication
34329568 | J:325395
First Author: Wu Q
Year: 2021
Journal: Cell Metab
Title: Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis.
Volume: 33
Issue: 10
Pages: 1988-2003.e7
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Publication
26124130 | J:223722
First Author: Ramakrishnan SK
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Maternal intestinal HIF-2α is necessary for sensing iron demands of lactation in mice.
Volume: 112
Issue: 28
Pages: E3738-47
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Publication
29480820 | J:261174
First Author: Ghosh MC
Year: 2018
Journal: J Clin Invest
Title: Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia.
Volume: 128
Issue: 4
Pages: 1317-1325
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Publication
19439736 | J:150753
First Author: Skuli N
Year: 2009
Journal: Blood
Title: Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.
Volume: 114
Issue: 2
Pages: 469-77
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Publication
26731474 | J:231164
First Author: Chang YT
Year: 2016
Journal: J Clin Invest
Title: DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys.
Volume: 126
Issue: 2
Pages: 721-31
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Publication
32513733 | J:294116
First Author: Bhurke A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules.
Volume: 117
Issue: 25
Pages: 14532-14542
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Publication
23785149 | J:199643
First Author: Huang Z
Year: 2013
Journal: J Neurosci
Title: Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.
Volume: 33
Issue: 25
Pages: 10362-73
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Publication
23395174 | J:198049
First Author: Anderson SA
Year: 2013
Journal: Cell Metab
Title: The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.
Volume: 17
Issue: 2
Pages: 282-90
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Publication
21856340 | J:180719
First Author: An HJ
Year: 2011
Journal: Biochim Biophys Acta
Title: The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation.
Volume: 1813
Issue: 12
Pages: 2088-98
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9398602 | J:44322
First Author: Ladoux A
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses.
Volume: 240
Issue: 3
Pages: 552-6
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21742975 | J:179164
First Author: Vezys V
Year: 2011
Journal: J Immunol
Title: 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.
Volume: 187
Issue: 4
Pages: 1634-42
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Publication
23437279 | J:196069
First Author: Choi HJ
Year: 2013
Journal: PLoS One
Title: ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement.
Volume: 8
Issue: 2
Pages: e56949
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Publication
23897427 | J:205022
First Author: Sena JA
Year: 2013
Journal: Mol Cell Biol
Title: BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.
Volume: 33
Issue: 19
Pages: 3849-63
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Publication
25023702 | J:221254
First Author: Gómez-Maldonado L
Year: 2015
Journal: Oncogene
Title: EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.
Volume: 34
Issue: 20
Pages: 2609-20
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Publication
31515405 | J:297000
 
First Author: Hu CJ
Year: 2019
Journal: Eur Respir J
Title: Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.
Volume: 54
Issue: 6
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Publication
22407773 | J:310428
First Author: Oh H
Year: 2012
Journal: J Bone Miner Res
Title: Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.
Volume: 27
Issue: 6
Pages: 1335-44
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Publication
28232488 | J:318428
First Author: Yang X
Year: 2017
Journal: J Biol Chem
Title: The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration.
Volume: 292
Issue: 14
Pages: 5981-5991
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Publication
26245371 | J:247431
First Author: Wu D
Year: 2015
Journal: Nature
Title: Structural integration in hypoxia-inducible factors.
Volume: 524
Issue: 7565
Pages: 303-8
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Publication
24037094 | J:202020
First Author: Wei K
Year: 2013
Journal: Nat Med
Title: A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
Volume: 19
Issue: 10
Pages: 1331-1337
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Publication
28760743 | J:253318
First Author: Maier A
Year: 2017
Journal: FASEB J
Title: Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice.
Volume: 31
Issue: 11
Pages: 4971-4984
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Publication
29983349 | J:272671
 
First Author: Kiers D
Year: 2018
Journal: EBioMedicine
Title: Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.
Volume: 33
Pages: 144-156
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Publication
24282296 | J:205514
First Author: Anderson ER
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia.
Volume: 110
Issue: 50
Pages: E4922-30
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Publication
33024109 | J:303356
First Author: Hsu TS
Year: 2020
Journal: Nat Commun
Title: HIF-2α is indispensable for regulatory T cell function.
Volume: 11
Issue: 1
Pages: 5005
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Publication
15689487 | J:99217
First Author: Cowden Dahl KD
Year: 2005
Journal: Mol Biol Cell
Title: Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.
Volume: 16
Issue: 4
Pages: 1901-12
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33914705 | J:308502
 
First Author: Singhal R
Year: 2021
Journal: J Clin Invest
Title: HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Volume: 131
Issue: 12
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Publication
27546461 | J:251873
First Author: Xue X
Year: 2016
Journal: Cell Metab
Title: Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.
Volume: 24
Issue: 3
Pages: 447-461
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12832481 | J:84384
First Author: Park SK
Year: 2003
Journal: Mol Cell Biol
Title: Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Volume: 23
Issue: 14
Pages: 4959-71
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17342756 | J:119808
First Author: Steenhard BM
Year: 2007
Journal: Dev Dyn
Title: Kidney development and gene expression in the HIF2alpha knockout mouse.
Volume: 236
Issue: 4
Pages: 1115-25
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19498162 | J:149437
First Author: Dioum EM
Year: 2009
Journal: Science
Title: Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.
Volume: 324
Issue: 5932
Pages: 1289-93
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Publication
22095691 | J:180600
First Author: Hirata M
Year: 2012
Journal: Hum Mol Genet
Title: C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Volume: 21
Issue: 5
Pages: 1111-23
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Publication
31403471 | J:293718
First Author: Rattner A
Year: 2019
Journal: J Clin Invest
Title: Roles of HIFs and VEGF in angiogenesis in the retina and brain.
Volume: 129
Issue: 9
Pages: 3807-3820
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29136509 | J:248840
First Author: Palazon A
Year: 2017
Journal: Cancer Cell
Title: An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Volume: 32
Issue: 5
Pages: 669-683.e5
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Publication
23093773 | J:194014
First Author: Kurihara T
Year: 2012
Journal: J Clin Invest
Title: Targeted deletion of Vegfa in adult mice induces vision loss.
Volume: 122
Issue: 11
Pages: 4213-7
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22869907 | J:333641
First Author: Roda JM
Year: 2012
Journal: J Immunol
Title: Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
Volume: 189
Issue: 6
Pages: 3168-77
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Publication
28112274 | J:275118
 
First Author: Gardner PJ
Year: 2017
Journal: Sci Rep
Title: Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.
Volume: 7
Pages: 40830
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Publication
24497508 | J:206831
First Author: Ahn GO
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.
Volume: 111
Issue: 7
Pages: 2698-703
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Publication
38856651 | J:360360
 
First Author: Schreiber T
Year: 2024
Journal: J Cell Sci
Title: Reduced vacuolar ATPase protects mice from Friend virus infection - an unintended but instructive effect in Hif-2afl mice.
Volume: 137
Issue: 12
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38422022 | J:346095
First Author: Ma J
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Volume: 121
Issue: 10
Pages: e2309957121
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20194441 | J:263290
First Author: Takeda N
Year: 2010
Journal: Genes Dev
Title: Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.
Volume: 24
Issue: 5
Pages: 491-501
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25015343 | J:227457
First Author: Wong MS
Year: 2014
Journal: Circulation
Title: Vitamin D promotes vascular regeneration.
Volume: 130
Issue: 12
Pages: 976-86
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Publication
29967068 | J:263648
 
First Author: Kim YE
Year: 2018
Journal: Dis Model Mech
Title: HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Volume: 11
Issue: 7
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Publication
22897855 | J:191820
First Author: Leite de Oliveira R
Year: 2012
Journal: Cancer Cell
Title: Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Volume: 22
Issue: 2
Pages: 263-77
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27271565 | J:297699
First Author: Fecher RA
Year: 2016
Journal: J Immunol
Title: Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum.
Volume: 197
Issue: 2
Pages: 565-79
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Publication
22936665 | J:192921
First Author: Weigert A
Year: 2012
Journal: Blood
Title: HIF-1α is a negative regulator of plasmacytoid DC development in vitro and in vivo.
Volume: 120
Issue: 15
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