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Search results 601 to 700 out of 960 for Epo

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Epo/Epo<+>
Background: (C57BL/10 x CBA)F1 X CFLP
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epo/Epo
Background: (C57BL/10 x CBA)F1 X CFLP
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epo/Epo<+>
Background: involves: C57BL/6 * CBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epo/Epo
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Publication
7733961 | J:25054
First Author: Chicheportiche Y
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Identification in mouse macrophages of a new 4Kb mRNA present in hematopoietic tissues, which shares a short nucleotide sequence with erythropoietin mRNA.
Volume: 209
Issue: 3
Pages: 1076-81
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Genotype
Genotype
Symbol: Epx/Epx
Background: involves: 129P2/OlaHsd * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Epo-cre)44Mym/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Epo-cre)1Weng/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Epo-cre)241Weng/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
8343951 | J:40444
First Author: Witthuhn BA
Year: 1993
Journal: Cell
Title: JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin.
Volume: 74
Issue: 2
Pages: 227-36
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Publication
7889566 | J:23805
First Author: Klingmüller U
Year: 1995
Journal: Cell
Title: Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals.
Volume: 80
Issue: 5
Pages: 729-38
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Publication
1731775 | J:11574
First Author: Tsuchiya T
Year: 1992
Journal: Biochem Biophys Res Commun
Title: In vitro reconstitution of an erythropoietin gene transcription system using its 5'-flanking sequence and a nuclear extract from anemic kidney.
Volume: 182
Issue: 1
Pages: 137-43
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Publication
18054864 | J:132723
First Author: Milenkovic N
Year: 2007
Journal: Neuron
Title: Nociceptive tuning by stem cell factor/c-Kit signaling.
Volume: 56
Issue: 5
Pages: 893-906
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Publication
37883230 | J:351823
First Author: First NJ
Year: 2023
Journal: Cell Rep
Title: Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection.
Volume: 42
Issue: 11
Pages: 113294
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Publication
25429065 | J:230692
First Author: Huang L
Year: 2015
Journal: J Immunol
Title: Eosinophils mediate protective immunity against secondary nematode infection.
Volume: 194
Issue: 1
Pages: 283-90
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Publication
30285291 | J:269171
First Author: Percopo CM
Year: 2019
Journal: J Leukoc Biol
Title: Impact of eosinophil-peroxidase (EPX) deficiency on eosinophil structure and function in mouse airways.
Volume: 105
Issue: 1
Pages: 151-161
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Publication
32344203 | J:295367
First Author: Bapst AM
Year: 2020
Journal: Biochim Biophys Acta Gene Regul Mech
Title: Cre-mediated, loxP independent sequential recombination of a tripartite transcriptional stop cassette allows for partial read-through transcription.
Volume: 1863
Issue: 8
Pages: 194568
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Genotype
Genotype
Symbol: Kit/Kit Tg(PDGFB-EPO)321Zbz/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Epo-cre)#Weng/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR019767 | EPO/TPO_CS
Type: Conserved_site
Description: Erythropoietin, a plasma glycoprotein, is the primary physiological mediator of erythropoiesis []. Itis involved in the regulation of the level of peripheral erythrocytes by stimulating the differentiation of erythroid progenitor cells, found in the spleen and bone marrow, into mature erythrocytes []. It is primarily produced in adult kidneys and foetal liver, acting by attachment to specific binding sites on erythroid progenitor cells, stimulating their differentiation []. Severe kidney dysfunction causes reduction in the plasma levels of erythropoietin,resulting in chronic anaemia - injection of purified erythropoietin into the blood stream can help to relieve this type of anaemia. Levels of erythropoietin in plasma fluctuate with varying oxygen tension of the blood, but androgens and prostaglandins also modulate the levels to some extent []. Erythropoietin glycoprotein sequences are well conserved, a consequence of which is that the hormones are cross-reactive among mammals,i.e. that from one species, say human, can stimulate erythropoiesis inother species, say mouse or rat []. Thrombopoeitin (TPO), a glycoprotein, is the mammalian0 hormone which functions as a megakaryocytic lineage specific growth and differentiation factor affecting the proliferation and maturation from their committed progenitor cells acting at a late stage of megakaryocyte development. It acts as a circulating regulator of platelet numbers.EPO and TPO are evolutionary related. As a signature pattern, this entry represents a conserved region located at the N-terminal extremity of mature EPO and TPO and that includes two cysteines which have been shown, in human EPO, to be implicated in disulphide bonds.
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Publication
19064729 | J:148303
First Author: Samuels AL
Year: 2009
Journal: Blood
Title: Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation.
Volume: 113
Issue: 16
Pages: 3845-56
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Publication
8773591 | J:34899
First Author: Horton MA
Year: 1996
Journal: J Leukoc Biol
Title: Cloning of the murine eosinophil peroxidase gene (mEPO): characterization of a conserved subgroup of mammalian hematopoietic peroxidases.
Volume: 60
Issue: 2
Pages: 285-94
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Publication
10490101 | J:57476
First Author: Marine JC
Year: 1999
Journal: Cell
Title: SOCS3 is essential in the regulation of fetal liver erythropoiesis.
Volume: 98
Issue: 5
Pages: 617-27
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Publication
21149549 | J:176862
First Author: Choi D
Year: 2010
Journal: J Exp Med
Title: Erythropoietin protects against diabetes through direct effects on pancreatic beta cells.
Volume: 207
Issue: 13
Pages: 2831-42
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Publication
22044999 | J:220935
 
First Author: Teng R
Year: 2011
Journal: Nat Commun
Title: Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production.
Volume: 2
Pages: 520
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Publication
24769002 | J:215345
 
First Author: Ruiz M
Year: 2014
Journal: Neuropharmacology
Title: Neurodegenerative changes are prevented by Erythropoietin in the pmn model of motoneuron degeneration.
Volume: 83
Pages: 137-53
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Publication
11895800 | J:75841
First Author: Jegalian AG
Year: 2002
Journal: Blood
Title: Erythropoietin receptor haploinsufficiency and in vivo interplay with granulocyte-macrophage colony-stimulating factor and interleukin 3.
Volume: 99
Issue: 7
Pages: 2603-5
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Publication
36130519 | J:329317
First Author: Chakraborty S
Year: 2022
Journal: Cell Rep
Title: Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo.
Volume: 40
Issue: 12
Pages: 111360
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Publication
27068470 | J:235179
First Author: Hamanaka RB
Year: 2016
Journal: Cell Rep
Title: The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.
Volume: 15
Issue: 3
Pages: 451-459
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Publication
20952675 | J:165787
First Author: Jackson A
Year: 2010
Journal: J Immunol
Title: Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
Volume: 185
Issue: 10
Pages: 6198-204
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Publication
26481148 | J:226762
First Author: Pradeep S
Year: 2015
Journal: Cancer Cell
Title: Erythropoietin Stimulates Tumor Growth via EphB4.
Volume: 28
Issue: 5
Pages: 610-622
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Publication
21256055 | J:168064
First Author: Nairz M
Year: 2011
Journal: Immunity
Title: Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-κB-inducible immune pathways.
Volume: 34
Issue: 1
Pages: 61-74
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Publication
29282252 | J:259218
First Author: Khalil S
Year: 2018
Journal: J Exp Med
Title: Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor.
Volume: 215
Issue: 2
Pages: 661-679
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Publication
18423195 | J:145307
First Author: Boutin AT
Year: 2008
Journal: Cell
Title: Epidermal sensing of oxygen is essential for systemic hypoxic response.
Volume: 133
Issue: 2
Pages: 223-34
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Publication
23319700 | J:195889
First Author: Dev A
Year: 2013
Journal: J Exp Med
Title: Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins.
Volume: 210
Issue: 2
Pages: 225-32
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Publication
14581001 | J:102593
First Author: Temkin V
Year: 2003
Journal: Cytokine
Title: Tumor necrosis factors in a murine model of allergic peritonitis: effects on eosinophil accumulation and inflammatory mediators' release.
Volume: 24
Issue: 3
Pages: 74-80
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Publication
23885016 | J:203289
First Author: Luk CT
Year: 2013
Journal: Endocrinology
Title: In vivo knockdown of adipocyte erythropoietin receptor does not alter glucose or energy homeostasis.
Volume: 154
Issue: 10
Pages: 3652-9
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Publication
33205838 | J:354088
First Author: Talukder MAH
Year: 2021
Journal: Muscle Nerve
Title: Obligatory role of Schwann cell-specific erythropoietin receptors in erythropoietin-induced functional recovery and neurogenic muscle atrophy after nerve injury.
Volume: 63
Issue: 2
Pages: 268-272
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Publication
34433021 | J:314206
First Author: Fernandez Garcia-Agudo L
Year: 2021
Journal: Cell Rep
Title: Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus.
Volume: 36
Issue: 8
Pages: 109548
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Publication
17990289 | J:294857
First Author: Yang HY
Year: 2008
Journal: J Cell Biochem
Title: Gene expression profiling related to the enhanced erythropoiesis in mouse bone marrow cells.
Volume: 104
Issue: 1
Pages: 295-303
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Publication
33084574 | J:298679
   
First Author: Riou R
Year: 2020
Journal: Elife
Title: ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription.
Volume: 9
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Publication
25289670 | J:222457
First Author: Usenko T
Year: 2014
Journal: PLoS One
Title: Leukemogenic Ptpn11 allele causes defective erythropoiesis in mice.
Volume: 9
Issue: 10
Pages: e109682
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Publication
34921133 | J:317684
First Author: Hidalgo D
Year: 2021
Journal: Nat Commun
Title: EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis.
Volume: 12
Issue: 1
Pages: 7334
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Publication
32548608 | J:301396
First Author: Di Giandomenico S
Year: 2020
Journal: Blood
Title: Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors.
Volume: 136
Issue: 9
Pages: 1044-1054
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Publication
37892192 | J:358069
 
First Author: Maymand S
Year: 2023
Journal: Biomolecules
Title: Role of Cytokine-Inducible SH2 Domain-Containing (CISH) Protein in the Regulation of Erythropoiesis.
Volume: 13
Issue: 10
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Publication
25108527 | J:221931
First Author: Xu M
Year: 2014
Journal: Nat Med
Title: An acetate switch regulates stress erythropoiesis.
Volume: 20
Issue: 9
Pages: 1018-26
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Publication
2163695 | J:10590
First Author: Winkelmann JC
Year: 1990
Journal: Blood
Title: The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p.
Volume: 76
Issue: 1
Pages: 24-30
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Publication
1318465 | J:11826
 
First Author: Longmore GD
Year: 1992
Journal: Leukemia
Title: Mutation in murine erythropoietin receptor induces erythropoietin-independent erythroid proliferation in vitro, polycythemia in vivo.
Volume: 6 Suppl 3
Pages: 130S-134S
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Publication
8440347 | J:17939
First Author: Dong YJ
Year: 1993
Journal: Exp Hematol
Title: Evidence for an accessory component that increases the affinity of the erythropoietin receptor.
Volume: 21
Issue: 3
Pages: 483-6
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Publication
8697800 | J:34723
First Author: Bruch J
Year: 1996
Journal: Cytogenet Cell Genet
Title: Mapping of type I loci from human chromosome 7 reveals segments of conserved synteny on pig chromosomes 3, 9, and 18.
Volume: 73
Issue: 3
Pages: 164-7
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Publication
9585060 | J:47493
First Author: Muñoz SE
Year: 1998
Journal: Cancer Lett
Title: Differential modulation by dietary n-6 or n-9 unsaturated fatty acids on the development of two murine mammary gland tumors having different metastatic capabilities.
Volume: 126
Issue: 2
Pages: 149-55
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Publication
10068686 | J:53438
First Author: Czyzyk-Krzeska MF
Year: 1999
Journal: Blood
Title: Identification of the poly(C) binding protein in the complex associated with the 3' untranslated region of erythropoietin messenger RNA.
Volume: 93
Issue: 6
Pages: 2111-20
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Publication
16297853 | J:106627
First Author: Wang J
Year: 2006
Journal: Arch Biochem Biophys
Title: Role of eosinophil peroxidase in host defense and disease pathology.
Volume: 445
Issue: 2
Pages: 256-60
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Publication
17464207 | J:136607
First Author: Kim MO
Year: 2007
Journal: Mol Cells
Title: Human erythropoietin induces lung failure and erythrocytosis in transgenic mice.
Volume: 23
Issue: 1
Pages: 17-22
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Publication
19683511 | J:155629
First Author: Ozolins TR
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Defects in embryonic development of EGLN1/PHD2 knockdown transgenic mice are associated with induction of Igfbp in the placenta.
Volume: 390
Issue: 3
Pages: 372-6
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Publication
30252956 | J:295498
First Author: Beneduce E
Year: 2019
Journal: Am J Hematol
Title: Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis.
Volume: 94
Issue: 1
Pages: 10-20
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Publication
- | J:43104
First Author: Ohmori J
Year: 1997
Journal: Acta Histochem Cytochem
Title: Eosinophil peroxidase deficiency in humans and mice.
Volume: 30
Issue: 3
Pages: 231-236
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Publication
17327401 | J:145426
First Author: Waskow C
Year: 2007
Journal: Blood
Title: Kit is essential for PMA-inflammation-induced mast-cell accumulation in the skin.
Volume: 109
Issue: 12
Pages: 5363-70
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Publication
27049514 | J:253794
First Author: Drake MG
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus.
Volume: 55
Issue: 3
Pages: 387-94
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Publication
10880228 | J:67142
First Author: Gregory RC
Year: 2000
Journal: Cytokine
Title: Subtraction cloning and initial characterization of novel epo-immediate response genes.
Volume: 12
Issue: 7
Pages: 845-57
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Publication
17024180 | J:200427
First Author: Funakoshi-Tago M
Year: 2006
Journal: EMBO J
Title: Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2.
Volume: 25
Issue: 20
Pages: 4763-72
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Publication
7796808 | J:26494
First Author: Yoshimura A
Year: 1995
Journal: EMBO J
Title: A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.
Volume: 14
Issue: 12
Pages: 2816-26
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Publication
9129017 | J:44332
First Author: Matsumoto A
Year: 1997
Journal: Blood
Title: CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation.
Volume: 89
Issue: 9
Pages: 3148-54
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Publication
2175360 | J:10887
First Author: Kuramochi S
Year: 1990
Journal: J Mol Biol
Title: Characterization of murine erythropoietin receptor genes.
Volume: 216
Issue: 3
Pages: 567-75
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Publication
30185409 | J:266594
 
First Author: Chiu SK
Year: 2018
Journal: Development
Title: A novel role for Lyl1 in primitive erythropoiesis.
Volume: 145
Issue: 19
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Publication
7695919 | J:25736
First Author: Kung TT
Year: 1995
Journal: Am J Respir Cell Mol Biol
Title: Mast cells modulate allergic pulmonary eosinophilia in mice.
Volume: 12
Issue: 4
Pages: 404-9
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Publication
19591826 | J:154494
First Author: Rex TS
Year: 2009
Journal: Exp Eye Res
Title: Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse.
Volume: 89
Issue: 5
Pages: 735-40
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Publication
23773177 | J:280587
First Author: Hines-Beard J
Year: 2013
Journal: Curr Gene Ther
Title: Identification of a therapeutic dose of continuously delivered erythropoietin in the eye using an inducible promoter system.
Volume: 13
Issue: 4
Pages: 275-81
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Publication
17950726 | J:141468
First Author: Wang J
Year: 2007
Journal: Exp Cell Res
Title: Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation.
Volume: 313
Issue: 20
Pages: 4120-9
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Publication
9476909 | J:114264
First Author: Broide DH
Year: 1998
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice.
Volume: 18
Issue: 2
Pages: 218-25
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Publication
24647735 | J:229804
First Author: Alnaeeli M
Year: 2014
Journal: Diabetes
Title: Erythropoietin signaling: a novel regulator of white adipose tissue inflammation during diet-induced obesity.
Volume: 63
Issue: 7
Pages: 2415-31
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Publication
18519842 | J:280684
First Author: d'Uscio LV
Year: 2008
Journal: Hypertension
Title: Erythropoietin increases endothelial biosynthesis of tetrahydrobiopterin by activation of protein kinase B alpha/Akt1.
Volume: 52
Issue: 1
Pages: 93-9
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Publication
30209118 | J:269870
First Author: Artuso I
Year: 2018
Journal: Blood
Title: Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model.
Volume: 132
Issue: 21
Pages: 2286-2297
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Publication
28242826 | J:272145
 
First Author: Xu K
Year: 2017
Journal: Physiol Rep
Title: Gender differences in hypoxic acclimatization in cyclooxygenase-2-deficient mice.
Volume: 5
Issue: 4
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Publication
11739165 | J:115417
First Author: Hisakawa H
Year: 2001
Journal: Blood
Title: Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors.
Volume: 98
Issue: 13
Pages: 3618-25
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Publication
19836979 | J:233137
First Author: Huang X
Year: 2010
Journal: Blood Cells Mol Dis
Title: Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo.
Volume: 44
Issue: 1
Pages: 1-6
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Publication
18413601 | J:134347
First Author: Taoufik E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury.
Volume: 105
Issue: 16
Pages: 6185-90
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Publication
23636173 | J:324431
First Author: Hu MC
Year: 2013
Journal: Kidney Int
Title: The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
Volume: 84
Issue: 3
Pages: 468-81
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Publication
12239135 | J:79372
First Author: Suzuki N
Year: 2002
Journal: Blood
Title: Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality.
Volume: 100
Issue: 7
Pages: 2279-88
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Publication
16781691 | J:133760
First Author: Tada H
Year: 2006
Journal: Cardiovasc Res
Title: Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion.
Volume: 71
Issue: 3
Pages: 466-77
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Publication
27456828 | J:279674
First Author: Li LX
Year: 2016
Journal: Infect Immun
Title: Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens.
Volume: 84
Issue: 10
Pages: 2833-41
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Publication
26563310 | J:324494
First Author: Dey S
Year: 2016
Journal: J Mol Endocrinol
Title: Erythropoietin regulates POMC expression via STAT3 and potentiates leptin response.
Volume: 56
Issue: 2
Pages: 55-67
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Publication
25715089 | J:259751
First Author: Naito Y
Year: 2015
Journal: J Hypertens
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