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Search results 601 to 652 out of 652 for Fus

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Type

Details

Score

Publication

21358643 | J:172305

First Author:	Polymenidou M
Year:	2011
Journal:	Nat Neurosci
Title:	Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
Volume:	14
Issue:	4
Pages:	459-68

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Publication

21777389 | J:190788

First Author:	Fiesel FC
Year:	2011
Journal:	FEBS J
Title:	TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.
Volume:	278
Issue:	19
Pages:	3550-68

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Publication

28404604 | J:243352

First Author:	Chujo T
Year:	2017
Journal:	EMBO J
Title:	Unusual semi-extractability as a hallmark of nuclear body-associated architectural noncoding RNAs.
Volume:	36
Issue:	10
Pages:	1447-1462

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Publication

33159853 | J:305781

First Author:	Wang Y
Year:	2020
Journal:	Immunity
Title:	A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin.
Volume:	53
Issue:	6
Pages:	1151-1167.e6

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Publication

38729967 | J:348394

First Author:	Shao H
Year:	2024
Journal:	Nat Commun
Title:	Fused in sarcoma (FUS) inhibits milk production efficiency in mammals.
Volume:	15
Issue:	1
Pages:	3953

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Publication

19124016 | -

First Author:	Jobert L
Year:	2009
Journal:	Exp Cell Res
Title:	PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function.
Volume:	315
Issue:	7
Pages:	1273-86

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Publication

22019700 | -

First Author:	Leichter M
Year:	2011
Journal:	Biochim Biophys Acta
Title:	A fraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex.
Volume:	1814
Issue:	12
Pages:	1812-24

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Publication

26612539 | -

First Author:	Kashyap M
Year:	2015
Journal:	Sci Rep
Title:	Structural delineation of stem-loop RNA binding by human TAF15 protein.
Volume:	5

Pages:	17298

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Protein Domain

IPR034875 | TAF15

Type:

Family

Description:

TATA binding associated factor 15 (TAF15) belongs to the TET (TAF15/EWS/TLS) or FET (FUS/EWS/TLS) protein family []. It is a nuclear RNA-binding protein that is associated with a distinct population of TFIID and RNA polymerase II complexes []. It also interacts with the U1 snRNP component of the spliceosome []. TAF15 can be methylated by protein arginine N-methyltransferase 1 (PRMT1), and this modification is a crucial event determining its proper localization and gene regulatory function []. It has been linked to familial amyotrophic lateral sclerosis (FALS) [].TAF15/EWS/TLS family members include human FUS (Fused in liposarcoma), EWS (Ewing Sarcoma) and TAF15 (TATA binding associated factor 15), and the Drosophila orthologue Cabeza. They are RNA binding proteins that contain a transcriptional-activation domain (EAD), 3 glycine-arginine (RGG) rich regions, an RNA-binding domain (RBD), and a zinc finger domain [, ]. They are involved in transcription and alternative splicing. They are subjected to different environmental signals that induce post-translational modifications in their RBD and in the RGG domains, thus modulating their activity []. TAF15/EWS/TLS play important roles in oncogenesis and neuronal disease [].

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Publication

38972779 | J:357808

First Author:	Pelaez MC
Year:	2024
Journal:	Neurotherapeutics
Title:	Reversal of cognitive deficits in FUS(R521G) amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.
Volume:	21
Issue:	5
Pages:	e00388

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Publication

24525297 | J:208762

First Author:	Nozawa YI
Year:	2014
Journal:	Dev Biol
Title:	Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis.
Volume:	388
Issue:	2
Pages:	170-80

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Publication

35474517 | J:338848

First Author:	Jensen BK
Year:	2022
Journal:	Glia
Title:	Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice.
Volume:	70
Issue:	7
Pages:	1426-1449

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Publication

23095749 | J:193770

First Author:	Tashiro Y
Year:	2012
Journal:	J Biol Chem
Title:	Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.
Volume:	287
Issue:	51
Pages:	42984-94

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Publication

38493058 | J:357871

First Author:	Milani M
Year:	2024
Journal:	Neurotherapeutics
Title:	Neuroprotective effects of niclosamide on disease progression via inflammatory pathways modulation in SOD1-G93A and FUS-associated amyotrophic lateral sclerosis models.
Volume:	21
Issue:	3
Pages:	e00346

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Publication

33288687 | J:300945

First Author:	Dubey S
Year:	2020
Journal:	Proc Natl Acad Sci U S A
Title:	Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer's disease.
Volume:	117
Issue:	51
Pages:	32691-32700

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Publication

29066368 | J:268619

First Author:	Liu M
Year:	2018
Journal:	Brain Res
Title:	Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease.
Volume:	1678

Pages:	138-145

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Publication

38616297 | J:359543

First Author:	Bae J
Year:	2024
Journal:	J Neuroimaging
Title:	Feasibility of measuring blood-brain barrier permeability using ultra-short echo time radial magnetic resonance imaging.
Volume:	34
Issue:	3
Pages:	320-328

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Publication

35580186 | J:333664

First Author:	Hoffman BU
Year:	2022
Journal:	Proc Natl Acad Sci U S A
Title:	Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2.
Volume:	119
Issue:	21
Pages:	e2115821119

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Publication

29194538 | J:257001

First Author:	So E
Year:	2018
Journal:	Hum Mol Genet
Title:	Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.
Volume:	27
Issue:	3
Pages:	463-474

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Publication

38047084 | J:343582

First Author:	Guo H
Year:	2023
Journal:	iScience
Title:	Effects of focused ultrasound in a "clean" mouse model of ultrasonic neuromodulation.
Volume:	26
Issue:	12
Pages:	108372

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Publication

35842440 | J:326817

First Author:	Moiseev D
Year:	2022
Journal:	Sci Rep
Title:	C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model.
Volume:	12
Issue:	1
Pages:	12160

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Publication

11146553 | J:66390

First Author:	Pérez-Losada J
Year:	2000
Journal:	Oncogene
Title:	Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma.
Volume:	19
Issue:	52
Pages:	6015-22

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Publication

26056265 | J:223767

First Author:	Barmada SJ
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1.
Volume:	112
Issue:	25
Pages:	7821-6

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Publication

28396410 | J:242130

First Author:	Ciryam P
Year:	2017
Journal:	Proc Natl Acad Sci U S A
Title:	Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
Volume:	114
Issue:	20
Pages:	E3935-E3943

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Publication

25193032 | J:253702

First Author:	Ajroud-Driss S
Year:	2015
Journal:	Biochim Biophys Acta
Title:	Sporadic and hereditary amyotrophic lateral sclerosis (ALS).
Volume:	1852
Issue:	4
Pages:	679-84

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Publication

31811026 | J:283949

First Author:	Wu X
Year:	2019
Journal:	Proc Natl Acad Sci U S A
Title:	Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics.

•

Publication

31092554 | J:281101

First Author:	Tischbein M
Year:	2019
Journal:	J Biol Chem
Title:	The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing.
Volume:	294
Issue:	26
Pages:	10194-10210

•

Publication

31896068 | J:297861

First Author:	Wang Y
Year:	2020
Journal:	Biomed Pharmacother
Title:	Downregulation of miR-200a protects cardiomyocyte against apoptosis.
Volume:	123

Pages:	109303

•

Publication

34307380 | J:340205

First Author:	Kai H
Year:	2021
Journal:	Front Cell Dev Biol
Title:	LncRNA NORAD Promotes Vascular Endothelial Cell Injury and Atherosclerosis Through Suppressing VEGF Gene Transcription via Enhancing H3K9 Deacetylation by Recruiting HDAC6.
Volume:	9

Pages:	701628

•

Publication

34118929 | J:314497

First Author:	Milani M
Year:	2021
Journal:	J Neuroinflammation
Title:	Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis.
Volume:	18
Issue:	1
Pages:	132

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Protein

Q61545

Organism:	Mus musculus/domesticus
Length:	655
Fragment?:	false

•

Protein

Q9CRS5

Organism:	Mus musculus/domesticus
Length:	333
Fragment?:	true

•

Protein

Q3UI30

Organism:	Mus musculus/domesticus
Length:	655
Fragment?:	false

•

Protein

Q5SUT0

Organism:	Mus musculus/domesticus
Length:	618
Fragment?:	false

•

Protein

Q5SUS9

Organism:	Mus musculus/domesticus
Length:	661
Fragment?:	false

•

Protein

Q6NVA3

Organism:	Mus musculus/domesticus
Length:	656
Fragment?:	false

•

Publication

37554284 | J:342533

First Author:	Karakatsani ME
Year:	2023
Journal:	Theranostics
Title:	Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients.
Volume:	13
Issue:	12
Pages:	4102-4120

•

Publication

26816005 | J:231220

First Author:	Ansseau E
Year:	2016
Journal:	PLoS One
Title:	Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
Volume:	11
Issue:	1
Pages:	e0146893

•

Protein

Q8BQ46

Organism:	Mus musculus/domesticus
Length:	557
Fragment?:	false

•

Protein

Q3TLE4

Organism:	Mus musculus/domesticus
Length:	518
Fragment?:	false

•

Protein

F6QCI0

Organism:	Mus musculus/domesticus
Length:	324
Fragment?:	true

•

Publication

- | J:28909

First Author:	Griffin CS
Year:	1995
Journal:	Mouse Genome
Title:	In Situ hybridisation assigns cDNAs from a normalised human foetal brain library to specific mouse tissues
Volume:	93
Issue:	3
Pages:	868-70

•

Publication

24129315 | J:306378

First Author:	Guo A
Year:	2014
Journal:	Mol Cell Proteomics
Title:	Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume:	13
Issue:	1
Pages:	372-87

•

Publication

- | J:82809

First Author:	European Mouse Mutant Archive
Year:	2003
Journal:	Unpublished
Title:	Information obtained from the European Mouse Mutant Archive (EMMA)

•

Publication

11217851 | J:65060

First Author:	Kawai J
Year:	2001
Journal:	Nature
Title:	Functional annotation of a full-length mouse cDNA collection.
Volume:	409
Issue:	6821
Pages:	685-90

•

Publication

11042159 | J:68323

First Author:	Carninci P
Year:	2000
Journal:	Genome Res
Title:	Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume:	10
Issue:	10
Pages:	1617-30

•

Publication

10349636 | J:80645

First Author:	Carninci P
Year:	1999
Journal:	Methods Enzymol
Title:	High-efficiency full-length cDNA cloning.
Volume:	303

Pages:	19-44

•

Publication

11076861 | J:68324

First Author:	Shibata K
Year:	2000
Journal:	Genome Res
Title:	RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume:	10
Issue:	11
Pages:	1757-71

•

Publication

16141073 | -

First Author:	Katayama S
Year:	2005
Journal:	Science
Title:	Antisense transcription in the mammalian transcriptome.
Volume:	309
Issue:	5740
Pages:	1564-6

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Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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