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Search results 601 to 637 out of 637 for Gnas

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0.022s

Type

Details

Score

Allele

Gt(ROSA)26Sor<tm5Mom> | MGI:5788276

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Peter Mombaerts
Allele Type:	Targeted
Attribute String:	Conditional ready, Dominant negative, No functional change, Reporter

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Strain

MGI:5785025 | B6;129P2-Or8a1<tm39(Gnas*)Mom>/MomJ

Attribute String:

mutant stock, targeted mutation

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Strain

MGI:6145387 | C57BL/6-Tg(Or10j5-Or6a2*D126R*R127D,-Gnas*Q227L,-ECFP*)1Hsak/Hsak

Attribute String:

mutant strain, coisogenic, transgenic

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Genotype

Symbol:	Or8a1/Or8a1
Background:	B6;129P2-Or8a1/MomJ
Zygosity:	hm
Has Mutant Allele:	true

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Genotype

Symbol:	Or8a1/Or8a1
Background:	involves: 129P2/OlaHsd * C57BL/6
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Or8a1/Or8a1<+>
Background:	B6;129P2-Or8a1/MomJ
Zygosity:	ht
Has Mutant Allele:	true

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Strain

MGI:5787580 | B6;129P2-Or8a1<tm37(Or10j5*,Gnas*)Mom>/MomJ

Attribute String:

targeted mutation, mutant stock

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Genotype

Symbol:	Gpa33/Gpa33<+> Hprt1/?
Background:	involves: 129S7/SvEvBrd * C57BL/6J
Zygosity:	cn
Has Mutant Allele:	true

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Genotype

Symbol:	Or8a1/Or8a1<+>
Background:	B6;129P2-Or8a1/MomJ
Zygosity:	ht
Has Mutant Allele:	true

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Allele

Pthlh<tm1Hmk> | MGI:2154515

Name:	parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Allele Type:	Targeted
Attribute String:	Null/knockout

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Genotype

Symbol:	Gnas/Gnas Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Or8a1/Or8a1
Background:	involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Zygosity:	cn
Has Mutant Allele:	true

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Strain

MGI:5788278 | B6;129P2-Gt(ROSA)26Sor<tm5Mom>/MomJ

Attribute String:

targeted mutation, mutant stock

•

Genotype

Symbol:	Apc/Apc<+> Gpa33/Gpa33<+> Hprt1/?
Background:	involves: 129S7/SvEvBrd * C57BL/6J
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

32531271 | J:293397

First Author:	Coles GL
Year:	2020
Journal:	Cancer Cell
Title:	Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells.
Volume:	38
Issue:	1
Pages:	129-143.e7

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Protein Coding Gene

MGI:97800 | Pthlh

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Genotype

Symbol:	Pthlh/Pthlh
Background:	either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Zygosity:	hm
Has Mutant Allele:	true

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Allele

Tg(TG-Gnas*R201H)1Rho | MGI:5308857

Name:	transgene insertion 1, Rhone-Poulenc Sante
Allele Type:	Transgenic
Attribute String:	Constitutively active, Inserted expressed sequence

•

Genotype

Symbol:	Gt(ROSA)26Sor/? Or8a1/?
Background:	involves: 129P2/OlaHsd * C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

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HT Experiment

E-GEOD-75878 | Reductions in hypothalamic Gfap expression, glial cells and alpha-tanycytes in lean and hypermetabolic Gnasxl-deficient mice

Series Id:	GSE75878
Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	ArrayExpress

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Publication

29573361 | J:310193

First Author:	Movahedi K
Year:	2018
Journal:	Biotechnol Bioeng
Title:	RoMo: An efficient strategy for functional mosaic analysis via stochastic Cre recombination and gene targeting in the ROSA26 locus.
Volume:	115
Issue:	7
Pages:	1778-1792

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Strain

MGI:5308860 | D2.Cg-Tg(TG-Gnas*R201H)1Rho/Orl

Attribute String:

congenic, mutant strain, transgenic

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Publication

7937980 | J:94546

First Author:	Michiels FM
Year:	1994
Journal:	Proc Natl Acad Sci U S A
Title:	Oncogenic potential of guanine nucleotide stimulatory factor alpha subunit in thyroid glands of transgenic mice.
Volume:	91
Issue:	22
Pages:	10488-92

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Publication

12743602 | J:83474

First Author:	Tourneur L
Year:	2003
Journal:	Oncogene
Title:	Loss of FADD protein expression results in a biased Fas-signaling pathway and correlates with the development of tumoral status in thyroid follicular cells.
Volume:	22
Issue:	18
Pages:	2795-804

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Publication

15964807 | J:99122

First Author:	Choi JD
Year:	2005
Journal:	Mol Cell Biol
Title:	A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island.
Volume:	25
Issue:	13
Pages:	5514-22

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Publication

29760048 | J:264284

First Author:	Untch BR
Year:	2018
Journal:	Cancer Res
Title:	Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.
Volume:	78
Issue:	16
Pages:	4642-4657

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Publication

34952228 | J:319852

First Author:	Liu Z
Year:	2022
Journal:	Bone
Title:	RANKL inhibition halts lesion progression and promotes bone remineralization in mice with fibrous dysplasia.
Volume:	156

Pages:	116301

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Publication

29282319 | J:260597

First Author:	Zhao X
Year:	2018
Journal:	Proc Natl Acad Sci U S A
Title:	Expression of an active Gα_s mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance.
Volume:	115
Issue:	3
Pages:	E428-E437

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Publication

17977899 | J:132034

First Author:	Kim J
Year:	2008
Journal:	Hum Mol Genet
Title:	In vivo YY1 knockdown effects on genomic imprinting.
Volume:	17
Issue:	3
Pages:	391-401

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Publication

25613955 | J:220746

First Author:	Gularte-Mérida R
Year:	2015
Journal:	BMC Genomics
Title:	Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.
Volume:	16

Pages:	16

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Publication

29530879 | J:260422

First Author:	Zhang B
Year:	2018
Journal:	Development
Title:	Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney.
Volume:	145
Issue:	6

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Publication

29471062 | J:262520

First Author:	Karaca A
Year:	2018
Journal:	Bone
Title:	Constitutive stimulatory G protein activity in limb mesenchyme impairs bone growth.
Volume:	110

Pages:	230-237

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Publication

34162750 | J:320980

First Author:	Cong Q
Year:	2021
Journal:	Sci Transl Med
Title:	A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification.
Volume:	13
Issue:	599

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Publication

38727310 | J:348357

First Author:	Michel Z
Year:	2024
Journal:	Cells
Title:	Transcriptomic Signature and Pro-Osteoclastic Secreted Factors of Abnormal Bone-Marrow Stromal Cells in Fibrous Dysplasia.
Volume:	13
Issue:	9

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Publication

19589963 | J:151078

First Author:	Imai T
Year:	2009
Journal:	Science
Title:	Pre-target axon sorting establishes the neural map topography.
Volume:	325
Issue:	5940
Pages:	585-90

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Publication

27080240 | J:356016

First Author:	Holmes AP
Year:	2016
Journal:	Mol Brain
Title:	Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice.
Volume:	9

Pages:	39

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Publication

- | J:28563

First Author:	Beechey CV
Year:	1995
Journal:	Mouse Genome
Title:	Genetic imprinting map
Volume:	93
Issue:	1
Pages:	89-92

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Publication

- | J:169366

First Author:	MouseBook^TM
Year:	2005
Journal:	Unpublished
Title:	Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.

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