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Search results 601 to 690 out of 690 for Hdac3

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Hits by Strain

Type Details Score
Protein
O88895
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
O88895-2
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
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Publication
24045946 | -
First Author: Zeng L
Year: 2013
Journal: J Biol Chem
Title: Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2.
Volume: 288
Issue: 44
Pages: 31853-66
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HT Experiment
E-GEOD-42537 | Nuclear Receptor Corepressors are Required for the Histone Deacetylase Activity of HDAC3 In Vivo (Microarray)
Series Id: GSE42537
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
21324898 | -
First Author: Pham L
Year: 2011
Journal: J Biol Chem
Title: HDAC3 and HDAC7 have opposite effects on osteoclast differentiation.
Volume: 286
Issue: 14
Pages: 12056-65
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Allele
Hdac3<em1Smoc> | MGI:7290182
Name: histone deacetylase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
22570481 | -
First Author: Demmerle J
Year: 2012
Journal: J Biol Chem
Title: The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity.
Volume: 287
Issue: 26
Pages: 22080-8
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HT Experiment
E-GEOD-72196 | Histone deacetylase 3 in concert with MeCP2 and FoxO regulate autism-associated behaviors
Series Id: GSE72196
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE72917 | Histone Deacetylase 3 is required for efficient T cell development
Series Id: E-GEOD-72917
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE122393 | The epigenetic regulator Histone Deacetylase 3 regulates the ontogeny and maintenance of tissue-resident macrophage [RNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE122529 | The epigenetic regulator Histone Deacetylase 3 regulates the ontogeny and maintenance of tissue-resident macrophage [scRNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11804585 | -
First Author: Fischle W
Year: 2002
Journal: Mol Cell
Title: Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
Volume: 9
Issue: 1
Pages: 45-57
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Publication
15561719 | -
First Author: Macfarlan T
Year: 2005
Journal: J Biol Chem
Title: Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.
Volume: 280
Issue: 8
Pages: 7346-58
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HT Experiment
GSE73666 | Effect of histone deacetylase 3 (Hdac3) deficiency in second heart field on embryonic heart development.
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:7623388 | C57BL/6JSmoc-Hdac3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR009269 | NKAP_C
Type: Domain
Description: This is the C-terminal domain found in NF-kappa-B-activating protein (Nkap) and a hypothetical open reading frame on chromosome 6, c6orf194. It is the HDAC3 binding domain required for transcriptional repression []. Nkap functions as a transcriptional repressor on Notch target genes, and is required for T cell development and acquisition of functional competency [, , ].
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Publication
19409814 | J:165961
First Author: Pajerowski AG
Year: 2009
Journal: Immunity
Title: NKAP is a transcriptional repressor of notch signaling and is required for T cell development.
Volume: 30
Issue: 5
Pages: 696-707
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Allele
Ncor1<tm1Laz> | MGI:3831119
Name: nuclear receptor co-repressor 1; targeted mutation 1, Mitchell A Lazar
Allele Type: Targeted
Attribute String: Hypomorph, Inserted expressed sequence
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Allele
Ncor2<tm1.1Laz> | MGI:6149745
 
Name: nuclear receptor co-repressor 2; targeted mutation 1.1, Mitchell A Lazar
Allele Type: Targeted
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Publication
27733359 | J:237941
First Author: Jiang Y
Year: 2017
Journal: Cancer Discov
Title: CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Volume: 7
Issue: 1
Pages: 38-53
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Strain
MGI:3831276 | C57BL/6-Ncor1<tm1Laz>
Attribute String: coisogenic, targeted mutation
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Genotype
Genotype
Symbol: Ncor1/Ncor1
Background: C57BL/6-Ncor1
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
E-GEOD-57809 | Genome-wide expression profiles in young and old mouse liver [RNA-seq]
Series Id: GSE57809
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Protein
Q5SZT7
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Protein
Q9D0F4
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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HT Experiment
GSE119498 | Haploinsufficiency of the intellectual disability-gene SETD5 disturbs developmental gene expression and cognition
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
21624937 | J:176824
First Author: Hsu FC
Year: 2011
Journal: J Exp Med
Title: NKAP is required for T cell maturation and acquisition of functional competency.
Volume: 208
Issue: 6
Pages: 1291-304
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Publication
22684107 | J:190466
First Author: Sinha RA
Year: 2012
Journal: J Clin Invest
Title: Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
Volume: 122
Issue: 7
Pages: 2428-38
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Strain
MGI:6275661 | B6(FVB)-Ncor2<tm1.1Laz> Ncor1<tm1Laz>
Attribute String: targeted mutation, mutant strain
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Genotype
Genotype
Symbol: Ncor1/Ncor1 Ncor2/Ncor2
Background: B6(FVB)-Ncor2 Ncor1
Zygosity: cx
Has Mutant Allele: true
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HT Experiment
E-GEOD-49383 | Gene expression data from mouse HDAC4 KO pups, postnatal day 3
Series Id: GSE49383
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25468569 | J:261836
First Author: Xiao N
Year: 2015
Journal: Blood
Title: Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl.
Volume: 125
Issue: 6
Pages: 941-8
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Publication
30455454 | J:271411
First Author: Deliu E
Year: 2018
Journal: Nat Neurosci
Title: Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition.
Volume: 21
Issue: 12
Pages: 1717-1727
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Publication
11006275 | J:113911
First Author: Wei LN
Year: 2000
Journal: J Biol Chem
Title: Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.
Volume: 275
Issue: 52
Pages: 40782-7
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Publication
32299058 | J:287342
First Author: Nakagawa T
Year: 2020
Journal: iScience
Title: The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.
Volume: 23
Issue: 4
Pages: 101030
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Publication
25865065 | J:222727
 
First Author: Sadler AJ
Year: 2015
Journal: Nat Commun
Title: The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.
Volume: 6
Pages: 6795
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Publication
28352664 | J:290770
First Author: Pardo M
Year: 2017
Journal: JCI Insight
Title: Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.
Volume: 2
Issue: 6
Pages: e91782
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Publication
29343442 | J:272343
First Author: Czimmerer Z
Year: 2018
Journal: Immunity
Title: The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.
Volume: 48
Issue: 1
Pages: 75-90.e6
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Publication
37751740 | J:359899
First Author: Abe Y
Year: 2023
Journal: Mol Cell
Title: RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Volume: 83
Issue: 19
Pages: 3421-3437.e11
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Publication
29757434 | J:263500
First Author: Liao J
Year: 2018
Journal: Endocrinology
Title: HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16.
Volume: 159
Issue: 7
Pages: 2520-2527
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Publication
38744281 | J:349110
First Author: Zhang J
Year: 2024
Journal: Cell
Title: Osr2 functions as a biomechanical checkpoint to aggravate CD8(+) T cell exhaustion in tumor.
Volume: 187
Issue: 13
Pages: 3409-3426.e24
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Publication
30952952 | J:274367
First Author: Iershov A
Year: 2019
Journal: Nat Commun
Title: The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.
Volume: 10
Issue: 1
Pages: 1566
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Publication
29472387 | J:260490
First Author: Gomis-Coloma C
Year: 2018
Journal: J Cell Biol
Title: Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells.
Volume: 217
Issue: 4
Pages: 1249-1268
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Publication
27052179 | J:235080
First Author: Thiagarajan D
Year: 2016
Journal: Cell Rep
Title: Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.
Volume: 15
Issue: 1
Pages: 181-96
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Publication
24992635 | J:215312
First Author: Escande C
Year: 2014
Journal: Aging Cell
Title: Deleted in Breast Cancer 1 regulates cellular senescence during obesity.
Volume: 13
Issue: 5
Pages: 951-3
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Publication
22726435 | J:187647
First Author: Zullo JM
Year: 2012
Journal: Cell
Title: DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.
Volume: 149
Issue: 7
Pages: 1474-87
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Publication
32442403 | J:290368
First Author: Wang Z
Year: 2020
Journal: Cancer Cell
Title: SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
Volume: 37
Issue: 6
Pages: 834-849.e13
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Publication
23069623 | J:208465
First Author: Galmozzi A
Year: 2013
Journal: Diabetes
Title: Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.
Volume: 62
Issue: 3
Pages: 732-42
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Publication
28035416 | J:323113
First Author: Shi Q
Year: 2017
Journal: Mol Med Rep
Title: Pallidin protein in neurodevelopment and its relation to the pathogenesis of schizophrenia.
Volume: 15
Issue: 2
Pages: 665-672
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Publication
30375985 | J:270914
First Author: Zhong S
Year: 2019
Journal: J Clin Invest
Title: Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Volume: 129
Issue: 1
Pages: 252-267
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Publication
21346255 | J:172830
First Author: Paz-Priel I
Year: 2011
Journal: Blood
Title: C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes.
Volume: 117
Issue: 15
Pages: 4085-94
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Publication
20705923 | J:178199
First Author: Jung SB
Year: 2010
Journal: Circ Res
Title: Histone deacetylase 3 antagonizes aspirin-stimulated endothelial nitric oxide production by reversing aspirin-induced lysine acetylation of endothelial nitric oxide synthase.
Volume: 107
Issue: 7
Pages: 877-87
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Publication
15713663 | J:98783
First Author: Fu M
Year: 2005
Journal: J Biol Chem
Title: Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
Volume: 280
Issue: 17
Pages: 16934-41
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Publication
24922625 | J:315807
First Author: Sharifi-Sanjani M
Year: 2014
Journal: J Am Heart Assoc
Title: Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3.
Volume: 3
Issue: 3
Pages: e000670
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Publication
28729730 | J:253049
First Author: Suelves N
Year: 2017
Journal: Sci Rep
Title: A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice.
Volume: 7
Issue: 1
Pages: 6082
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Publication
35269588 | J:327470
 
First Author: Martínez-Iglesias O
Year: 2022
Journal: Int J Mol Sci
Title: Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
Volume: 23
Issue: 5
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
27288453 | J:237141
First Author: Kyle SM
Year: 2016
Journal: Hum Mol Genet
Title: MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex.
Volume: 25
Issue: 14
Pages: 3029-3041
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Publication
24451378 | J:332478
First Author: Kumar P
Year: 2014
Journal: J Biol Chem
Title: Histone deacetylase inhibitors modulate the transcriptional regulation of guanylyl cyclase/natriuretic peptide receptor-a gene: interactive roles of modified histones, histone acetyltransferase, p300, AND Sp1.
Volume: 289
Issue: 10
Pages: 6991-7002
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Publication
28757615 | J:248803
First Author: Kim K
Year: 2017
Journal: Nat Commun
Title: RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network.
Volume: 8
Issue: 1
Pages: 162
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Publication
27031333 | J:251704
First Author: Jia H
Year: 2016
Journal: PLoS One
Title: The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.
Volume: 11
Issue: 3
Pages: e0152498
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Publication
21651971 | J:186744
First Author: Markovich D
Year: 2011
Journal: Exp Gerontol
Title: Increased lifespan in hyposulfatemic NaS1 null mice.
Volume: 46
Issue: 10
Pages: 833-5
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Publication
21127072 | J:170238
First Author: Micheli L
Year: 2011
Journal: J Biol Chem
Title: PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kappaB.
Volume: 286
Issue: 7
Pages: 5691-707
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Publication
22786766 | J:189755
First Author: Kobayashi T
Year: 2012
Journal: J Immunol
Title: IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis.
Volume: 189
Issue: 4
Pages: 1792-9
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Publication
33821572 | J:341516
First Author: Ma J
Year: 2021
Journal: EMBO Mol Med
Title: Menin-regulated Pbk controls high fat diet-induced compensatory beta cell proliferation.
Volume: 13
Issue: 5
Pages: e13524
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Publication
16917504 | J:245368
First Author: Alenghat T
Year: 2006
Journal: EMBO J
Title: The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor.
Volume: 25
Issue: 17
Pages: 3966-74
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Publication
10220385 | J:56457
First Author: Grozinger CM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Three proteins define a class of human histone deacetylases related to yeast Hda1p.
Volume: 96
Issue: 9
Pages: 4868-73
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Publication
19332113 | J:148412
First Author: Sharma M
Year: 2009
Journal: Gene
Title: The homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development.
Volume: 439
Issue: 1-2
Pages: 87-94
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Publication
19738286 | J:156967
First Author: Liang J
Year: 2009
Journal: J Biol Chem
Title: RNA-destabilizing factor tristetraprolin negatively regulates NF-kappaB signaling.
Volume: 284
Issue: 43
Pages: 29383-90
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Publication
21670149 | J:175091
First Author: Cui S
Year: 2011
Journal: Mol Cell Biol
Title: Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.
Volume: 31
Issue: 16
Pages: 3298-311
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Publication
22784989 | J:188159
First Author: Kim Y
Year: 2013
Journal: Mol Immunol
Title: DNA methyl transferase I acts as a negative regulator of allergic skin inflammation.
Volume: 53
Issue: 1-2
Pages: 1-14
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Publication
22908849 | J:191812
First Author: Ihlefeld K
Year: 2012
Journal: Biochem J
Title: Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts.
Volume: 447
Issue: 3
Pages: 457-64
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Publication
24583034 | J:210331
 
First Author: Worlitzer MM
Year: 2014
Journal: Neuroscience
Title: The Notch co-repressor protein NKAP is highly expressed in adult mouse subventricular zone neural progenitor cells.
Volume: 266
Pages: 138-49
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Publication
24523408 | J:212436
First Author: Duan Z
Year: 2014
Journal: J Biol Chem
Title: Tudor-SN, a novel coactivator of peroxisome proliferator-activated receptor γ protein, is essential for adipogenesis.
Volume: 289
Issue: 12
Pages: 8364-74
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Publication
25446073 | J:220290
First Author: Van den Bossche J
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.
Volume: 455
Issue: 3-4
Pages: 396-402
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Publication
26603935 | J:233185
First Author: Zhu X
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Upregulation of lncRNA MEG3 promotes hepatic insulin resistance via increasing FoxO1 expression.
Volume: 469
Issue: 2
Pages: 319-25
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Publication
29632070 | J:263940
First Author: Litke C
Year: 2018
Journal: J Biol Chem
Title: Histone deacetylase 4 shapes neuronal morphology via a mechanism involving regulation of expression of vascular endothelial growth factor D.
Volume: 293
Issue: 21
Pages: 8196-8207
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Publication
31827695 | J:285263
 
First Author: Zuo Z
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD47 Deficiency Attenuates Isoproterenol-Induced Cardiac Remodeling in Mice.
Volume: 2019
Pages: 7121763
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Publication
33293505 | J:306451
First Author: Yu XH
Year: 2020
Journal: Cell Death Dis
Title: LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis.
Volume: 11
Issue: 12
Pages: 1043
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Publication
24688469 | J:310212
 
First Author: Cosín-Tomás M
Year: 2014
Journal: Front Aging Neurosci
Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise.
Volume: 6
Pages: 51
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Publication
35095417 | J:319732
 
First Author: Nieto-Estevez V
Year: 2021
Journal: Front Mol Neurosci
Title: HDAC1 Regulates Neuronal Differentiation.
Volume: 14
Pages: 815808
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Publication
38718305 | J:352273
First Author: Zhu J
Year: 2024
Journal: Cancer Res
Title: HDAC Inhibition Increases CXCL12 Secretion to Recruit Natural Killer Cells in Peripheral T-cell Lymphoma.
Volume: 84
Issue: 15
Pages: 2450-2467
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Publication
30620721 | J:285736
First Author: Singh VP
Year: 2019
Journal: Reproduction
Title: Oocyte-specific deletion of Hdac8 in mice reveals stage-specific effects on fertility.
Volume: 157
Issue: 3
Pages: 305-316
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Publication
31112333 | J:349647
First Author: Tao H
Year: 2019
Journal: J Bone Miner Res
Title: Klf4 Promotes Dentinogenesis and Odontoblastic Differentiation via Modulation of TGF-β Signaling Pathway and Interaction With Histone Acetylation.
Volume: 34
Issue: 8
Pages: 1502-1516
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Publication
24278330 | J:209778
First Author: Mielcarek M
Year: 2013
Journal: PLoS One
Title: HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.
Volume: 8
Issue: 11
Pages: e80849
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Publication
32971072 | J:296905
 
First Author: Zhang M
Year: 2020
Journal: J Mol Cell Cardiol
Title: CaMKII exacerbates heart failure progression by activating class I HDACs.
Volume: 149
Pages: 73-81
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Publication
30231063 | J:265858
First Author: Zeng L
Year: 2018
Journal: PLoS One
Title: Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways.
Volume: 13
Issue: 9
Pages: e0204438
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Publication
22505606 | J:197781
First Author: Robertson ED
Year: 2012
Journal: J Cell Sci
Title: ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways.
Volume: 125
Issue: Pt 14
Pages: 3320-32
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Publication
26361334 | J:243102
First Author: Yashiro T
Year: 2015
Journal: PLoS One
Title: PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells.
Volume: 10
Issue: 9
Pages: e0137699
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Publication
34390859 | J:314483
 
First Author: Ritter MJ
Year: 2021
Journal: Mol Metab
Title: Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.
Volume: 53
Pages: 101315
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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