| Type |
Details |
Score |
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
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|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
| Publication |
| First Author: |
Metallo CM |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. |
| Volume: |
481 |
| Issue: |
7381 |
| Pages: |
380-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puviindran V |
| Year: |
2024 |
| Journal: |
Res Sq |
| Title: |
Single-cell transcriptomic analyses of mouse idh1 mutant growth plate chondrocytes reveal distinct cell populations responsible for longitudinal growth and enchondroma formation. |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
378
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peters J |
| Year: |
1985 |
| Journal: |
Biochem Genet |
| Title: |
Linkage of lactate dehydrogenase-2, Ldh-2, in the mouse. |
| Volume: |
23 |
| Issue: |
3-4 |
| Pages: |
217-25 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
414
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tyr/Tyr |
| Background: |
involves: 129/Sv * 129S4/SvJae * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Trp53/Trp53 Tyr/Tyr |
| Background: |
involves: 129/Sv * 129S4/SvJae * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
sternum |
| Notes: |
primary sternal chondrocytes; multiple, similar alleles were created in cited papers; it is possible another Idh1 and/or Cre allele was used to generate these data |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; endonuclease-mediated mutation 1, Nabeel Bardeesy |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; targeted mutation 1.1, Cristina Pina |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; endonuclease-mediated mutation 2, Nabeel Bardeesy |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; targeted mutation 1.2, Cristina Pina |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
isocitrate dehydrogenase 1 (NADP+), soluble; targeted mutation 1.3, Cristina Pina |
| Allele Type: |
Targeted |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Penard-Lacronique V |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
IDH1, Histone Methylation, and So Forth. |
| Volume: |
30 |
| Issue: |
2 |
| Pages: |
192-194 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cairns RA |
| Year: |
2013 |
| Journal: |
Cancer Discov |
| Title: |
Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities. |
| Volume: |
3 |
| Issue: |
7 |
| Pages: |
730-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waitkus MS |
| Year: |
2018 |
| Journal: |
Cancer Cell |
| Title: |
Biological Role and Therapeutic Potential of IDH Mutations in Cancer. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
186-195 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karpel-Massler G |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
1067 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
244 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rubtsov N |
| Year: |
1988 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
Silver fox gene mapping: conserved chromosome regions in the order Carnivora. |
| Volume: |
48 |
| Issue: |
2 |
| Pages: |
95-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2017 |
| Journal: |
Cancer Cell |
| Title: |
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. |
| Volume: |
31 |
| Issue: |
6 |
| Pages: |
820-832.e3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2019 |
| Journal: |
JCI Insight |
| Title: |
Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Palma S |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Changes in muscle cell metabolism and mechanotransduction are associated with myopathic phenotype in a mouse model of collagen VI deficiency. |
| Volume: |
8 |
| Issue: |
2 |
| Pages: |
e56716 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dovey OM |
| Year: |
2017 |
| Journal: |
Blood |
| Title: |
Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia. |
| Volume: |
130 |
| Issue: |
17 |
| Pages: |
1911-1922 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu M |
| Year: |
2018 |
| Journal: |
Int J Biol Sci |
| Title: |
DJ-1 Deficiency Protects Hepatic Steatosis by Enhancing Fatty Acid Oxidation in Mice. |
| Volume: |
14 |
| Issue: |
13 |
| Pages: |
1892-1900 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bauchle CJ |
| Year: |
2021 |
| Journal: |
Diabetes |
| Title: |
Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function. |
| Volume: |
70 |
| Issue: |
8 |
| Pages: |
1717-1728 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen R |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma. |
| Volume: |
111 |
| Issue: |
39 |
| Pages: |
14217-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang LE |
| Year: |
2019 |
| Journal: |
Carcinogenesis |
| Title: |
Friend or foe-IDH1 mutations in glioma 10 years on. |
| Volume: |
40 |
| Issue: |
11 |
| Pages: |
1299-1307 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noorani I |
| Year: |
2020 |
| Journal: |
Genome Biol |
| Title: |
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
181 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walker T |
| Year: |
1996 |
| Journal: |
Mouse Genome |
| Title: |
Methylglyoxal dehydrogenase (EC 1.2.1.23): No enzyme detection in mouse inbred strains |
| Volume: |
94 |
| Issue: |
1 |
| Pages: |
149-51 |
|
•
•
•
•
•
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