| Type |
Details |
Score |
| Publication |
| First Author: |
Freeman BE |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Regulation of innate CD8+ T-cell activation mediated by cytokines. |
| Volume: |
109 |
| Issue: |
25 |
| Pages: |
9971-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Degrandi D |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. |
| Volume: |
179 |
| Issue: |
11 |
| Pages: |
7729-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamamoto M |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. |
| Volume: |
301 |
| Issue: |
5633 |
| Pages: |
640-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones TG |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. |
| Volume: |
183 |
| Issue: |
8 |
| Pages: |
5251-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Flórido M |
| Year: |
2005 |
| Journal: |
Infect Immun |
| Title: |
Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection. |
| Volume: |
73 |
| Issue: |
6 |
| Pages: |
3577-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swann JB |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. |
| Volume: |
105 |
| Issue: |
2 |
| Pages: |
652-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marnik EA |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
208-221 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yousif AS |
| Year: |
2021 |
| Journal: |
Immunity |
| Title: |
The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells. |
| Volume: |
54 |
| Issue: |
2 |
| Pages: |
235-246.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kontoyiannis D |
| Year: |
2002 |
| Journal: |
J Exp Med |
| Title: |
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease. |
| Volume: |
196 |
| Issue: |
12 |
| Pages: |
1563-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van Rossum AM |
| Year: |
2005 |
| Journal: |
Infect Immun |
| Title: |
Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model. |
| Volume: |
73 |
| Issue: |
11 |
| Pages: |
7718-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zandian M |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination. |
| Volume: |
6 |
| Issue: |
2 |
| Pages: |
e16820 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vitry MA |
| Year: |
2012 |
| Journal: |
Infect Immun |
| Title: |
Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice. |
| Volume: |
80 |
| Issue: |
12 |
| Pages: |
4271-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wüthrich M |
| Year: |
2011 |
| Journal: |
J Clin Invest |
| Title: |
Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice. |
| Volume: |
121 |
| Issue: |
2 |
| Pages: |
554-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen D |
| Year: |
2023 |
| Journal: |
Immunity |
| Title: |
CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma. |
| Volume: |
56 |
| Issue: |
9 |
| Pages: |
2086-2104.e8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ueda N |
| Year: |
2006 |
| Journal: |
Int Immunol |
| Title: |
CD1d-restricted NKT cell activation enhanced homeostatic proliferation of CD8+ T cells in a manner dependent on IL-4. |
| Volume: |
18 |
| Issue: |
9 |
| Pages: |
1397-404 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madala SK |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis. |
| Volume: |
184 |
| Issue: |
7 |
| Pages: |
3955-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rosborough BR |
| Year: |
2013 |
| Journal: |
Blood |
| Title: |
Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction. |
| Volume: |
121 |
| Issue: |
18 |
| Pages: |
3619-30 |
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•
•
•
•
•
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| Publication |
| First Author: |
Coers J |
| Year: |
2007 |
| Journal: |
Cell Microbiol |
| Title: |
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
2344-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoon J |
| Year: |
2016 |
| Journal: |
J Exp Med |
| Title: |
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. |
| Volume: |
213 |
| Issue: |
10 |
| Pages: |
2147-66 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Meiser P |
| Year: |
2023 |
| Journal: |
Cancer Cell |
| Title: |
A distinct stimulatory cDC1 subpopulation amplifies CD8(+) T cell responses in tumors for protective anti-cancer immunity. |
| Volume: |
41 |
| Issue: |
8 |
| Pages: |
1498-1515.e10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bhattacharyya S |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation. |
| Volume: |
108 |
| Issue: |
23 |
| Pages: |
9554-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gui J |
| Year: |
2016 |
| Journal: |
J Invest Dermatol |
| Title: |
Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation. |
| Volume: |
136 |
| Issue: |
10 |
| Pages: |
1990-2002 |
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•
•
•
•
•
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| Publication |
| First Author: |
Gao D |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases. |
| Volume: |
112 |
| Issue: |
42 |
| Pages: |
E5699-705 |
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•
•
•
•
•
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| Publication |
| First Author: |
Hillen MR |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0130830 |
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•
•
•
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| Publication |
| First Author: |
Kuo CC |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide. |
| Volume: |
178 |
| Issue: |
10 |
| Pages: |
6100-8 |
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| First Author: |
Bode KA |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction. |
| Volume: |
182 |
| Issue: |
4 |
| Pages: |
2176-84 |
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•
•
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| First Author: |
Kupz A |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes. |
| Volume: |
9 |
| Issue: |
5 |
| Pages: |
e97418 |
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| First Author: |
Cheung H |
| Year: |
2005 |
| Journal: |
J Immunol |
| Title: |
Accessory protein-like is essential for IL-18-mediated signaling. |
| Volume: |
174 |
| Issue: |
9 |
| Pages: |
5351-7 |
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| First Author: |
Kobayashi EH |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. |
| Volume: |
7 |
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| First Author: |
Parikh BA |
| Year: |
2015 |
| Journal: |
PLoS Pathog |
| Title: |
Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells. |
| Volume: |
11 |
| Issue: |
12 |
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e1005323 |
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| First Author: |
Fallet B |
| Year: |
2016 |
| Journal: |
Sci Immunol |
| Title: |
Interferon-driven deletion of antiviral B cells at the onset of chronic infection. |
| Volume: |
1 |
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4 |
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| First Author: |
VanLith ML |
| Year: |
2002 |
| Journal: |
Int Immunol |
| Title: |
MUC1-specific anti-tumor responses: molecular requirements for CD4-mediated responses. |
| Volume: |
14 |
| Issue: |
8 |
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873-82 |
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| First Author: |
Kara EE |
| Year: |
2015 |
| Journal: |
Nat Commun |
| Title: |
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. |
| Volume: |
6 |
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| First Author: |
Pichler AC |
| Year: |
2023 |
| Journal: |
Immunity |
| Title: |
TCR-independent CD137 (4-1BB) signaling promotes CD8(+)-exhausted T cell proliferation and terminal differentiation. |
| Volume: |
56 |
| Issue: |
7 |
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1631-1648.e10 |
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Kawabe T |
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2020 |
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Nat Commun |
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Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state. |
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Byrne KT |
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2016 |
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Cell Rep |
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CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer. |
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Uematsu S |
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Nat Immunol |
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Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. |
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McKee AS |
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J Immunol |
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CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development. |
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JCI Insight |
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Murine models of Pneumocystis infection recapitulate human primary immune disorders. |
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Vladimer GI |
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The NLRP12 inflammasome recognizes Yersinia pestis. |
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Int J Mol Sci |
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YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. |
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Proc Natl Acad Sci U S A |
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Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. |
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Nat Immunol |
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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. |
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Nat Immunol |
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Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. |
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Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells. |
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•
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
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•
•
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•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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•
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•
•
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
|
| DO Term |
|
•
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•
•
•
|
| Allele |
| Name: |
interleukin 12b; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
interleukin 12b; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
interleukin 12b; targeted mutation 3, Shanghai Model Organisms Center |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
335
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion GFp40, Iain L Campbell |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion GFIl12, Iain L Campbell |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carr DJ |
| Year: |
2002 |
| Journal: |
DNA Cell Biol |
| Title: |
Unforeseen consequences of IL-12 expression in the eye of GFAP-IL12 transgenic mice following herpes simplex virus type 1 infection. |
| Volume: |
21 |
| Issue: |
5-6 |
| Pages: |
467-73 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Al-Khatib K |
| Year: |
2002 |
| Journal: |
J Neuroimmunol |
| Title: |
Resistance to ocular herpes simplex virus type 1 infection in IL-12 transgenic mice. |
| Volume: |
132 |
| Issue: |
1-2 |
| Pages: |
41-8 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Hofer M |
| Year: |
2004 |
| Journal: |
Am J Pathol |
| Title: |
Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice. |
| Volume: |
165 |
| Issue: |
3 |
| Pages: |
949-58 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Krauthausen M |
| Year: |
2011 |
| Journal: |
Am J Pathol |
| Title: |
Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12. |
| Volume: |
179 |
| Issue: |
5 |
| Pages: |
2346-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kobayashi T |
| Year: |
2014 |
| Journal: |
J Immunol |
| Title: |
NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. |
| Volume: |
192 |
| Issue: |
4 |
| Pages: |
1918-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Negishi H |
| Year: |
2012 |
| Journal: |
Nat Immunol |
| Title: |
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. |
| Volume: |
13 |
| Issue: |
7 |
| Pages: |
659-66 |
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•
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•
•
•
|
| Publication |
| First Author: |
Robles-Rebollo I |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
4342 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Muñoz-Rojas AR |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Co-stimulation with opposing macrophage polarization cues leads to orthogonal secretion programs in individual cells. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
301 |
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•
•
|
| Publication |
| First Author: |
Tartey S |
| Year: |
2014 |
| Journal: |
EMBO J |
| Title: |
Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. |
| Volume: |
33 |
| Issue: |
20 |
| Pages: |
2332-48 |
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•
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•
•
•
|
| Publication |
| First Author: |
Yamamoto M |
| Year: |
2004 |
| Journal: |
Nature |
| Title: |
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. |
| Volume: |
430 |
| Issue: |
6996 |
| Pages: |
218-22 |
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•
•
|
| Publication |
| First Author: |
Rabe JL |
| Year: |
2019 |
| Journal: |
Cancer Res |
| Title: |
IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression. |
| Volume: |
79 |
| Issue: |
14 |
| Pages: |
3702-3713 |
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