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Search results 601 to 700 out of 826 for Insr

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Type Details Score
Publication
27052174 | J:235082
First Author: Shimazu J
Year: 2016
Journal: Cell Rep
Title: Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148.
Volume: 15
Issue: 1
Pages: 27-35
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Publication
15249583 | J:91846
First Author: Harrington LS
Year: 2004
Journal: J Cell Biol
Title: The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
Volume: 166
Issue: 2
Pages: 213-23
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Publication
16455755 | J:107908
First Author: Fecchi K
Year: 2006
Journal: FASEB J
Title: Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.
Volume: 20
Issue: 6
Pages: 705-7
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Publication
8034026 | J:19199
First Author: Larsson-Blomberg L
Year: 1994
Journal: FEBS Lett
Title: Isolation of tyrosine kinase related genes expressed in the early hematopoietic system.
Volume: 348
Issue: 2
Pages: 119-25
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Publication
35741102 | J:326523
 
First Author: Kheirollahi V
Year: 2022
Journal: Cells
Title: Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.
Volume: 11
Issue: 12
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Publication
- | J:133634
     
First Author: RIKEN BioResource Center/RIKEN Genomic Sciences Center
Year: 2008
Journal: PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/)
Title: A Large Scale Mutagenesis Program in RIKEN GSC
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Publication
22055502 | J:179687
First Author: Banks AS
Year: 2011
Journal: Cell Metab
Title: Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.
Volume: 14
Issue: 5
Pages: 587-97
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Publication
25249504 | J:218426
First Author: Kahraman S
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Volume: 307
Issue: 10
Pages: E906-18
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Publication
11897712 | J:106827
First Author: Duvillié B
Year: 2002
Journal: Endocrinology
Title: Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin.
Volume: 143
Issue: 4
Pages: 1530-7
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Publication
26369386 | J:227002
 
First Author: Ferrón SR
Year: 2015
Journal: Nat Commun
Title: Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis.
Volume: 6
Pages: 8265
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Publication
23129807 | J:192831
First Author: Lin JC
Year: 2013
Journal: Mol Cell Biol
Title: RBM4 promotes pancreas cell differentiation and insulin expression.
Volume: 33
Issue: 2
Pages: 319-27
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Publication
23349485 | J:208570
First Author: Lee KM
Year: 2013
Journal: Diabetes
Title: Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice.
Volume: 62
Issue: 6
Pages: 1855-64
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Publication
35874829 | J:327184
 
First Author: Xiao Z
Year: 2022
Journal: Front Cell Dev Biol
Title: The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.
Volume: 10
Pages: 882994
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Publication
1347472 | J:2945
First Author: Colombo MP
Year: 1992
Journal: Mamm Genome
Title: Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16.
Volume: 2
Issue: 2
Pages: 130-4
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Publication
24258027 | J:321229
First Author: Murakami-Kawaguchi S
Year: 2014
Journal: Cell Tissue Res
Title: Expression of Ins1 and Ins2 genes in mouse fetal liver.
Volume: 355
Issue: 2
Pages: 303-14
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Publication
22980982 | J:187963
First Author: Talchai C
Year: 2012
Journal: Cell
Title: Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.
Volume: 150
Issue: 6
Pages: 1223-34
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Publication
24391734 | J:211117
First Author: Pais RS
Year: 2013
Journal: PLoS One
Title: Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.
Volume: 8
Issue: 12
Pages: e83028
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Publication
23906066 | J:199282
First Author: Günschmann C
Year: 2013
Journal: Dev Cell
Title: Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition.
Volume: 26
Issue: 2
Pages: 176-87
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Publication
26141512 | J:315113
 
First Author: Häfner R
Year: 2015
Journal: Mol Cell Endocrinol
Title: Fgfr2 is required for the expansion of the early adrenocortical primordium.
Volume: 413
Pages: 168-77
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Publication
27861515 | J:241923
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
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Publication
15254900 | J:91730
First Author: Verma-Kurvari S
Year: 2004
Journal: Dev Dyn
Title: Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.
Volume: 230
Issue: 4
Pages: 660-5
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Publication
23907538 | J:203690
First Author: Martinez-Lopez N
Year: 2013
Journal: EMBO Rep
Title: Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development.
Volume: 14
Issue: 9
Pages: 795-803
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Publication
23300479 | J:197599
First Author: Pitetti JL
Year: 2013
Journal: PLoS Genet
Title: Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.
Volume: 9
Issue: 1
Pages: e1003160
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Publication
9344654 | J:40255
First Author: Fletcher CF
Year: 1997
Journal: Genomics
Title: Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.
Volume: 45
Issue: 2
Pages: 313-9
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Publication
36843585 | J:333829
 
First Author: Lopez-Tello J
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age.
Volume: 14
Pages: 1116770
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
35733999 | J:326089
 
First Author: Ghnaimawi S
Year: 2022
Journal: Front Physiol
Title: The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring's Muscle Development and Energy Homeostasis.
Volume: 13
Pages: 881624
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Publication
35084365 | J:326026
First Author: Prokopuk L
Year: 2022
Journal: Reproduction
Title: An essential role for Polycomb Repressive Complex 2 in the mouse ovary.
Volume: 163
Issue: 3
Pages: 167-182
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
31958132 | J:296621
First Author: Huang G
Year: 2020
Journal: Carcinogenesis
Title: RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Volume: 41
Issue: 9
Pages: 1294-1305
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Publication
28036389 | J:251101
First Author: Yang WM
Year: 2016
Journal: PLoS One
Title: Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1.
Volume: 11
Issue: 12
Pages: e0169039
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UniProt Feature
UniProt Feature
Begin: 1220
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 1220
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UniProt Feature
UniProt Feature
Begin: 891
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 891
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UniProt Feature
UniProt Feature
Begin: 1173
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 1173
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UniProt Feature
UniProt Feature
Begin: 935
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 935
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UniProt Feature
UniProt Feature
Begin: 983
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 983
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UniProt Feature
UniProt Feature
Begin: 608
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 608
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UniProt Feature
UniProt Feature
Begin: 628
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 628
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UniProt Feature
UniProt Feature
Begin: 460
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 460
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UniProt Feature
UniProt Feature
Begin: 1303
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 1303
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UniProt Feature
UniProt Feature
Begin: 1242
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 1242
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UniProt Feature
UniProt Feature
Begin: 970
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 970
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UniProt Feature
UniProt Feature
Begin: 911
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 911
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UniProt Feature
UniProt Feature
Begin: 671
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 671
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UniProt Feature
UniProt Feature
Begin: 536
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 536
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UniProt Feature
UniProt Feature
Begin: 397
Description: Phosphotyrosine; by INSR
Type: modified residue
End: 397
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UniProt Feature
UniProt Feature
Begin: 376
Description: Phosphotyrosine; by SRC and INSR
Type: modified residue
End: 376
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UniProt Feature
UniProt Feature
Begin: 379
Description: Phosphotyrosine; by SRC and INSR
Type: modified residue
End: 379
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UniProt Feature
UniProt Feature
Begin: 9
Description: Phosphotyrosine; by SRC and INSR
Type: modified residue
End: 9
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UniProt Feature
UniProt Feature
Begin: 14
Description: Phosphotyrosine; by ABL1 and INSR
Type: modified residue
End: 14
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DO Term
DOID:0070220 | familial hyperinsulinemic hypoglycemia 5
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UniProt Feature
UniProt Feature
Begin: 488
Description: Phosphotyrosine; by SRC, LCK, INSR and EGFR
Type: modified residue
End: 488
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Allele
Insr<em2Smoc> | MGI:7290557
Name: insulin receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6770862 | C57BL/6JSmoc-Insr<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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UniProt Feature
UniProt Feature
Begin: 291
Description: WTKF motif; mediates interaction with adapter protein complex 2 and is essential for its function in clathrin-mediated endocytosis of INSR
Type: short sequence motif
End: 294
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UniProt Feature
UniProt Feature
Begin: 229
Description: YERL motif; mediates interaction with adapter protein complex 2 and is essential for its function in clathrin-mediated endocytosis of INSR
Type: short sequence motif
End: 232
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Allele
Insr<tm1Dac> | MGI:1857204
Name: insulin receptor; targeted mutation 1, Domenico Accili
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Insr<tm1Jja> | MGI:2149629
Name: insulin receptor; targeted mutation 1, Jacques Jami
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Insr<em1Smoc> | MGI:7290556
Name: insulin receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Actb<tm1(INSR)Dac> | MGI:4831148
Name: actin, beta; targeted mutation 1, Dominico Accili
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change
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Genotype
Genotype
Symbol: Insr/Insr
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Insr/Insr
Background: involves: 129S2/SvPas * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0050470 | Donohue syndrome
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Strain
MGI:6475603 | C57BL/6JSmoc-Insr<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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