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Search results 601 to 700 out of 727 for Irf3

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Type Details Score
Publication
30337468 | J:269888
First Author: Cheng Y
Year: 2018
Journal: J Exp Med
Title: Mycobacterium tuberculosis-induced IFN-β production requires cytosolic DNA and RNA sensing pathways.
Volume: 215
Issue: 11
Pages: 2919-2935
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Publication
29107214 | J:272784
 
First Author: Yu A
Year: 2017
Journal: Int Immunopharmacol
Title: Tim-3 enhances brain inflammation by promoting M1 macrophage polarization following intracerebral hemorrhage in mice.
Volume: 53
Pages: 143-148
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Publication
22902624 | J:191578
First Author: Enesa K
Year: 2012
Journal: J Biol Chem
Title: Pellino1 is required for interferon production by viral double-stranded RNA.
Volume: 287
Issue: 41
Pages: 34825-35
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Publication
36384137 | J:350509
First Author: Zhang Q
Year: 2022
Journal: Mol Cell
Title: AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.
Volume: 82
Issue: 23
Pages: 4519-4536.e7
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Publication
30943264 | J:285681
First Author: Ye L
Year: 2019
Journal: PLoS Pathog
Title: USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.
Volume: 15
Issue: 4
Pages: e1007680
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Publication
34533996 | J:311757
First Author: Zhang C
Year: 2021
Journal: Sci Adv
Title: Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity.
Volume: 7
Issue: 38
Pages: eabb5933
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Publication
30814308 | J:274572
First Author: Zhang MX
Year: 2019
Journal: J Immunol
Title: USP20 Promotes Cellular Antiviral Responses via Deconjugating K48-Linked Ubiquitination of MITA.
Volume: 202
Issue: 8
Pages: 2397-2406
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Publication
39673708 | J:361352
First Author: Zhang X
Year: 2024
Journal: Cell Rep
Title: Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Volume: 43
Issue: 12
Pages: 115060
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Publication
34969857 | J:322222
 
First Author: Liu Z
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein PINLYP regulates type I interferon innate immunity.
Volume: 119
Issue: 1
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Publication
38809975 | J:351315
First Author: Ren T
Year: 2024
Journal: Sci Adv
Title: Exercise activates interferon response of the liver via Gpld1 to enhance antiviral innate immunity.
Volume: 10
Issue: 22
Pages: eadk5011
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Publication
31076723 | J:315640
First Author: Song X
Year: 2020
Journal: Cell Mol Immunol
Title: E3 ubiquitin ligase RNF170 inhibits innate immune responses by targeting and degrading TLR3 in murine cells.
Volume: 17
Issue: 8
Pages: 865-874
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Publication
22745163 | J:186390
First Author: Li Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.
Volume: 109
Issue: 29
Pages: 11770-5
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Publication
21892174 | J:176439
First Author: Zhang Z
Year: 2011
Journal: Nat Immunol
Title: The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.
Volume: 12
Issue: 10
Pages: 959-65
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Publication
30883606 | J:273550
First Author: Skjesol A
Year: 2019
Journal: PLoS Pathog
Title: The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2.
Volume: 15
Issue: 3
Pages: e1007684
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Publication
23142775 | J:200472
First Author: Parvatiyar K
Year: 2012
Journal: Nat Immunol
Title: The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.
Volume: 13
Issue: 12
Pages: 1155-61
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Publication
20581830 | J:162319
First Author: Kim H
Year: 2010
Journal: Nat Immunol
Title: The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.
Volume: 11
Issue: 8
Pages: 743-50
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Publication
20363211 | J:163572
First Author: Tanaka H
Year: 2010
Journal: Arch Biochem Biophys
Title: The CagA protein of Helicobacter pylori suppresses the functions of dendritic cell in mice.
Volume: 498
Issue: 1
Pages: 35-42
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Publication
26811330 | J:236198
First Author: Song S
Year: 2016
Journal: Mol Cell Biol
Title: Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus.
Volume: 36
Issue: 7
Pages: 1136-51
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Publication
28534493 | J:250595
 
First Author: Sun H
Year: 2017
Journal: Nat Commun
Title: USP13 negatively regulates antiviral responses by deubiquitinating STING.
Volume: 8
Pages: 15534
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Publication
31988106 | J:295346
 
First Author: Liu F
Year: 2020
Journal: Mol Cell Biol
Title: Ipr1 Regulation by Cyclic GMP-AMP Synthase/Interferon Regulatory Factor 3 and Modulation of Irgm1 Expression via p53.
Volume: 40
Issue: 8
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Publication
34313226 | J:308289
   
First Author: Yang Z
Year: 2021
Journal: Elife
Title: RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination.
Volume: 10
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Publication
34901991 | J:320021
 
First Author: Li T
Year: 2022
Journal: J Exp Med
Title: TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance.
Volume: 219
Issue: 1
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Publication
35172162 | J:320434
First Author: Chen J
Year: 2022
Journal: Cell Rep
Title: TBK1-METTL3 axis facilitates antiviral immunity.
Volume: 38
Issue: 7
Pages: 110373
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Publication
35180274 | J:331534
First Author: Ma C
Year: 2022
Journal: PLoS Pathog
Title: p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signaling.
Volume: 18
Issue: 2
Pages: e1010295
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Publication
36223739 | J:345019
First Author: Liu H
Year: 2022
Journal: Cell Rep
Title: Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis.
Volume: 41
Issue: 2
Pages: 111469
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Publication
36972172 | J:348568
First Author: Kong L
Year: 2023
Journal: Cell Rep
Title: The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus.
Volume: 42
Issue: 4
Pages: 112306
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Publication
39213157 | J:354624
First Author: Liu W
Year: 2024
Journal: Cell Rep
Title: E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS.
Volume: 43
Issue: 9
Pages: 114687
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Protein
S4R1W6
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
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Publication
26305951 | J:226812
First Author: Lin D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6.
Volume: 112
Issue: 36
Pages: 11324-9
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Publication
18724357 | J:141011
First Author: Ishikawa H
Year: 2008
Journal: Nature
Title: STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Volume: 455
Issue: 7213
Pages: 674-8
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Publication
30944173 | J:280417
First Author: Dewi Pamungkas Putri D
Year: 2019
Journal: J Biol Chem
Title: PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.
Volume: 294
Issue: 21
Pages: 8412-8423
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Publication
36633157 | J:355570
First Author: Khaw YM
Year: 2023
Journal: EMBO Rep
Title: Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice.
Volume: 24
Issue: 3
Pages: e54228
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Publication
15210743 | J:120402
First Author: Perry AK
Year: 2004
Journal: J Exp Med
Title: Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection.
Volume: 199
Issue: 12
Pages: 1651-8
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Publication
22713470 | J:185967
First Author: Wang Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Apolipoprotein E-knockout mice show increased titers of serum anti-nuclear and anti-dsDNA antibodies.
Volume: 423
Issue: 4
Pages: 805-12
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Publication
19720838 | J:153779
First Author: Kovalenko A
Year: 2009
Journal: J Exp Med
Title: Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease.
Volume: 206
Issue: 10
Pages: 2161-77
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Publication
24307739 | J:207163
First Author: Blaauboer SM
Year: 2014
Journal: J Immunol
Title: MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.
Volume: 192
Issue: 1
Pages: 492-502
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Publication
21383019 | J:172084
First Author: Shiose S
Year: 2011
Journal: J Biol Chem
Title: Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.
Volume: 286
Issue: 17
Pages: 15543-55
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Publication
26100021 | J:228237
First Author: Khan KA
Year: 2015
Journal: Mol Cell Biol
Title: Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway.
Volume: 35
Issue: 17
Pages: 3029-43
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Publication
19191335 | J:156204
First Author: So EY
Year: 2009
Journal: Glia
Title: Theiler's virus infection induces TLR3-dependent upregulation of TLR2 critical for proinflammatory cytokine production.
Volume: 57
Issue: 11
Pages: 1216-26
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Publication
23209319 | J:190826
First Author: Zhou H
Year: 2013
Journal: J Immunol
Title: CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses.
Volume: 190
Issue: 1
Pages: 115-25
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Publication
23188796 | J:193120
First Author: Sen A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution.
Volume: 109
Issue: 50
Pages: 20667-72
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Publication
19494276 | J:149298
First Author: Yoshimi R
Year: 2009
Journal: J Immunol
Title: Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts.
Volume: 182
Issue: 12
Pages: 7527-38
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Publication
27593482 | J:325424
First Author: Zhang X
Year: 2016
Journal: Cell Mol Immunol
Title: Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production.
Volume: 13
Issue: 5
Pages: 578-83
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Publication
31782850 | J:292681
First Author: Ouyang W
Year: 2020
Journal: Cell Prolif
Title: SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection.
Volume: 53
Issue: 1
Pages: e12721
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Publication
22396652 | J:195399
First Author: Maelfait J
Year: 2012
Journal: PLoS Pathog
Title: A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.
Volume: 8
Issue: 3
Pages: e1002570
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Publication
35937499 | J:327606
 
First Author: Matissek SJ
Year: 2022
Journal: Oncotarget
Title: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling.
Volume: 13
Pages: 944-959
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Publication
25759027 | J:323785
First Author: Zhou M
Year: 2015
Journal: Immunol Res
Title: PTEN-Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injury.
Volume: 62
Issue: 1
Pages: 95-105
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Publication
19398754 | J:148498
First Author: Tzima S
Year: 2009
Journal: J Exp Med
Title: Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production.
Volume: 206
Issue: 5
Pages: 1167-79
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Publication
33976210 | J:306337
First Author: Xing J
Year: 2021
Journal: Nat Commun
Title: Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Volume: 12
Issue: 1
Pages: 2681
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Publication
30397349 | J:282512
First Author: Perkins DJ
Year: 2018
Journal: Nat Immunol
Title: Autocrine-paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling.
Volume: 19
Issue: 12
Pages: 1309-1318
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Publication
24493797 | J:208320
First Author: Fan Y
Year: 2014
Journal: J Exp Med
Title: USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.
Volume: 211
Issue: 2
Pages: 313-28
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Publication
20651301 | J:166476
First Author: Marchlik E
Year: 2010
Journal: J Leukoc Biol
Title: Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
Volume: 88
Issue: 6
Pages: 1171-80
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Publication
21949249 | J:177337
First Author: Clark K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.
Volume: 108
Issue: 41
Pages: 17093-8
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Publication
29410095 | J:271443
First Author: Lee YS
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Loss of toll-like receptor 3 aggravates hepatic inflammation but ameliorates steatosis in mice.
Volume: 497
Issue: 4
Pages: 957-962
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Publication
18266302 | J:132115
First Author: Koziczak-Holbro M
Year: 2008
Journal: Eur J Immunol
Title: IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes.
Volume: 38
Issue: 3
Pages: 788-96
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Publication
19825364 | J:155613
First Author: Hua F
Year: 2009
Journal: Biochem Biophys Res Commun
Title: The TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice.
Volume: 390
Issue: 3
Pages: 678-83
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Publication
29297844 | J:344124
First Author: Piret J
Year: 2018
Journal: J Gen Virol
Title: Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice.
Volume: 99
Issue: 2
Pages: 209-218
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Publication
27580796 | J:360012
 
First Author: Lee BR
Year: 2016
Journal: Sci Rep
Title: Combination of TLR1/2 and TLR3 ligands enhances CD4(+) T cell longevity and antibody responses by modulating type I IFN production.
Volume: 6
Pages: 32526
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Publication
26508631 | J:227257
First Author: Hu W
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation.
Volume: 112
Issue: 45
Pages: 13994-9
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Publication
32709741 | J:333361
First Author: Elsner C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells.
Volume: 117
Issue: 32
Pages: 19475-19486
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Publication
25385820 | J:318694
First Author: Klarquist J
Year: 2014
Journal: J Immunol
Title: STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells.
Volume: 193
Issue: 12
Pages: 6124-34
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Publication
30410068 | J:286922
First Author: Liuyu T
Year: 2019
Journal: Cell Res
Title: Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.
Volume: 29
Issue: 1
Pages: 67-79
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Publication
28411188 | J:247671
First Author: Lai R
Year: 2017
Journal: J Immunol
Title: Raf Kinase Inhibitor Protein Preferentially Promotes TLR3-Triggered Signaling and Inflammation.
Volume: 198
Issue: 10
Pages: 4086-4095
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Publication
18439848 | J:136289
First Author: Michallet MC
Year: 2008
Journal: Immunity
Title: TRADD protein is an essential component of the RIG-like helicase antiviral pathway.
Volume: 28
Issue: 5
Pages: 651-61
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Publication
34429383 | J:338455
 
First Author: Döring M
Year: 2021
Journal: Sci Signal
Title: Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine.
Volume: 14
Issue: 697
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Publication
23674823 | J:259727
First Author: Zhong B
Year: 2013
Journal: Sci Signal
Title: Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3.
Volume: 6
Issue: 275
Pages: ra35
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Publication
27717824 | J:240651
First Author: Ye X
Year: 2016
Journal: Biochem Biophys Res Commun
Title: MyD88 contributes to neuroinflammatory responses induced by cerebral ischemia/reperfusion in mice.
Volume: 480
Issue: 1
Pages: 69-74
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Publication
38459007 | J:352684
First Author: Chauhan M
Year: 2024
Journal: Cell Death Dis
Title: STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection.
Volume: 15
Issue: 3
Pages: 195
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Publication
22837208 | J:187887
First Author: Malur M
Year: 2012
Journal: J Virol
Title: LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3.
Volume: 86
Issue: 19
Pages: 10733-8
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Publication
22473004 | J:315816
First Author: Tong Y
Year: 2012
Journal: Cell Res
Title: Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice.
Volume: 22
Issue: 5
Pages: 822-35
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Publication
32075857 | J:287309
First Author: Zhang Z
Year: 2020
Journal: J Immunol
Title: OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Volume: 204
Issue: 7
Pages: 1904-1918
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Publication
29973649 | J:324871
First Author: Zhang H
Year: 2019
Journal: Cell Mol Immunol
Title: The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling.
Volume: 16
Issue: 10
Pages: 800-809
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Publication
36538592 | J:335000
First Author: Zhou W
Year: 2022
Journal: Sci Signal
Title: Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses.
Volume: 15
Issue: 765
Pages: eabo4356
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Publication
29150432 | J:257513
First Author: Bodur C
Year: 2018
Journal: EMBO J
Title: The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
Volume: 37
Issue: 1
Pages: 19-38
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Publication
36315588 | J:347114
First Author: Liu H
Year: 2022
Journal: PLoS Pathog
Title: Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling.
Volume: 18
Issue: 10
Pages: e1010921
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Publication
27094905 | J:296106
 
First Author: Lui PY
Year: 2016
Journal: Emerg Microbes Infect
Title: Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3.
Volume: 5
Pages: e39
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Publication
18471880 | J:136204
First Author: Dong LW
Year: 2008
Journal: Mol Immunol
Title: Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.
Volume: 45
Issue: 11
Pages: 3025-35
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Publication
17513724 | J:147848
First Author: Wang X
Year: 2007
Journal: J Immunol
Title: Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression.
Volume: 178
Issue: 11
Pages: 6770-6
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Publication
20724660 | J:164390
First Author: Arimoto K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense.
Volume: 107
Issue: 36
Pages: 15856-61
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Publication
18984593 | J:168298
First Author: Yoshida R
Year: 2008
Journal: J Biol Chem
Title: TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway.
Volume: 283
Issue: 52
Pages: 36211-20
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Publication
21106850 | J:168739
First Author: Joung SM
Year: 2011
Journal: J Immunol
Title: Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1.
Volume: 186
Issue: 1
Pages: 499-507
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Publication
23396947 | J:193597
First Author: Bruni D
Year: 2013
Journal: J Immunol
Title: A novel IRAK1-IKKε signaling axis limits the activation of TAK1-IKKβ downstream of TLR3.
Volume: 190
Issue: 6
Pages: 2844-56
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Publication
23604073 | J:198830
First Author: Cavlar T
Year: 2013
Journal: EMBO J
Title: Species-specific detection of the antiviral small-molecule compound CMA by STING.
Volume: 32
Issue: 10
Pages: 1440-50
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Publication
23700487 | J:200724
First Author: Meng Z
Year: 2013
Journal: PLoS One
Title: RNAi induces innate immunity through multiple cellular signaling pathways.
Volume: 8
Issue: 5
Pages: e64708
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Publication
24379396 | J:206367
First Author: Randall CM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus.
Volume: 111
Issue: 2
Pages: E265-72
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