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Search results 601 to 700 out of 1089 for Jak2

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Type Details Score
Publication
First Author: Stahl N
Year: 1994
Journal: Science
Title: Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.
Volume: 263
Issue: 5143
Pages: 92-5
Publication
First Author: Rampal R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Volume: 111
Issue: 50
Pages: E5401-10
Publication
First Author: Maschalidi S
Year: 2016
Journal: Blood
Title: Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice.
Volume: 128
Issue: 1
Pages: 60-71
Publication
First Author: Bezbradica JS
Year: 2014
Journal: Nat Immunol
Title: A role for the ITAM signaling module in specifying cytokine-receptor functions.
Volume: 15
Issue: 4
Pages: 333-42
Publication
First Author: Liu YE
Year: 2007
Journal: FEBS J
Title: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids.
Volume: 274
Issue: 13
Pages: 3351-62
Publication
First Author: Li B
Year: 2022
Journal: Blood
Title: BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
Volume: 139
Issue: 25
Pages: 3630-3646
Publication
First Author: Xin H
Year: 2013
Journal: J Biol Chem
Title: G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells.
Volume: 288
Issue: 19
Pages: 13842-9
Publication
First Author: Kagoya Y
Year: 2014
Journal: Blood
Title: JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.
Volume: 124
Issue: 19
Pages: 2996-3006
Publication
First Author: Ma JK
Year: 2024
Journal: Nat Commun
Title: TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia.
Volume: 15
Issue: 1
Pages: 3976
Publication  
First Author: Zhong Y
Year: 2022
Journal: Neuroscience
Title: JAK2/STAT3 Axis Intermediates Microglia/Macrophage Polarization During Cerebral Ischemia/Reperfusion Injury.
Volume: 496
Pages: 119-128
Publication
First Author: Jing X
Year: 2012
Journal: Cell Rep
Title: Crosstalk of humoral and cell-cell contact-mediated signals in postnatal body growth.
Volume: 2
Issue: 3
Pages: 652-65
Publication  
First Author: Han X
Year: 2023
Journal: J Clin Invest
Title: Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.
Volume: 133
Issue: 6
Publication
First Author: Yan D
Year: 2012
Journal: Blood
Title: Critical requirement for Stat5 in a mouse model of polycythemia vera.
Volume: 119
Issue: 15
Pages: 3539-49
Publication
First Author: Kleppe M
Year: 2018
Journal: Cancer Cell
Title: Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Volume: 33
Issue: 1
Pages: 29-43.e7
Publication
First Author: Ishikawa Y
Year: 2015
Journal: Haematologica
Title: Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
Volume: 100
Issue: 4
Pages: 439-51
Publication
First Author: Dutta A
Year: 2017
Journal: Blood
Title: Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways.
Volume: 130
Issue: 7
Pages: 920-932
Publication
First Author: Liu Q
Year: 2011
Journal: PLoS Biol
Title: Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.
Volume: 9
Issue: 1
Pages: e1000575
Publication
First Author: Le BV
Year: 2020
Journal: Cell Rep
Title: TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.
Volume: 33
Issue: 1
Pages: 108221
Publication  
First Author: Tsunekawa T
Year: 2017
Journal: EBioMedicine
Title: Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia.
Volume: 16
Pages: 172-183
Publication
First Author: Saiardi A
Year: 1997
Journal: Neuron
Title: Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia.
Volume: 19
Issue: 1
Pages: 115-26
Publication  
First Author: Mai HN
Year: 2019
Journal: Free Radic Biol Med
Title: Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling.
Volume: 131
Pages: 408-431
Publication
First Author: Yuan L
Year: 2018
Journal: J Cell Mol Med
Title: Heat-shock transcription factor 1 is critically involved in the ischaemia-induced cardiac hypertrophy via JAK2/STAT3 pathway.
Volume: 22
Issue: 9
Pages: 4292-4303
Publication
First Author: Santos J
Year: 2001
Journal: Oncogene
Title: Evidence of a possible epigenetic inactivation mechanism operating on a region of mouse chromosome 19 in gamma-radiation-induced thymic lymphomas.
Volume: 20
Issue: 17
Pages: 2186-9
Publication
First Author: Laranjeira ABA
Year: 2024
Journal: Blood
Title: In vivo ablation of NF-κB cascade effectors alleviates disease burden in myeloproliferative neoplasms.
Volume: 143
Issue: 23
Pages: 2414-2424
Publication
First Author: Edelmann B
Year: 2018
Journal: J Clin Invest
Title: JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Volume: 128
Issue: 10
Pages: 4359-4371
Publication
First Author: Mapes J
Year: 2017
Journal: PLoS Genet
Title: CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.
Volume: 13
Issue: 3
Pages: e1006654
Publication
First Author: Sebastián C
Year: 2008
Journal: J Immunol
Title: Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells.
Volume: 180
Issue: 9
Pages: 5898-906
Publication
First Author: Larner AC
Year: 1995
Journal: Biochim Biophys Acta
Title: Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes.
Volume: 1266
Issue: 3
Pages: 278-87
Publication
First Author: Kono DH
Year: 1996
Journal: Mamm Genome
Title: Jak3 maps to chromosome 8.
Volume: 7
Issue: 6
Pages: 476-7
Publication
First Author: Yeh TC
Year: 1999
Journal: Cell Mol Life Sci
Title: The Janus kinase family of protein tyrosine kinases and their role in signaling.
Volume: 55
Issue: 12
Pages: 1523-34
Publication
First Author: Schmidt U
Year: 2004
Journal: J Exp Med
Title: Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.
Volume: 199
Issue: 6
Pages: 785-95
Publication
First Author: Zabeau L
Year: 2004
Journal: Mol Endocrinol
Title: Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay.
Volume: 18
Issue: 1
Pages: 150-61
Publication
First Author: Fujinaka Y
Year: 2007
Journal: J Biol Chem
Title: Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.
Volume: 282
Issue: 42
Pages: 30707-17
Publication
First Author: Hansen G
Year: 2008
Journal: Cell
Title: The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.
Volume: 134
Issue: 3
Pages: 496-507
Publication
First Author: Wood AD
Year: 2009
Journal: Blood
Title: ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.
Volume: 114
Issue: 9
Pages: 1820-30
Publication
First Author: Doles J
Year: 2012
Journal: Genes Dev
Title: Age-associated inflammation inhibits epidermal stem cell function.
Volume: 26
Issue: 19
Pages: 2144-53
Publication
First Author: Witthuhn BA
Year: 1994
Journal: Nature
Title: Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.
Volume: 370
Issue: 6485
Pages: 153-7
Publication
First Author: Presky DH
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.
Volume: 93
Issue: 24
Pages: 14002-7
Publication
First Author: Nicholson SE
Year: 1999
Journal: EMBO J
Title: Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.
Volume: 18
Issue: 2
Pages: 375-85
Publication
First Author: Zhao L
Year: 2004
Journal: J Biol Chem
Title: Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.
Volume: 279
Issue: 42
Pages: 44093-100
Publication
First Author: Marinaccio C
Year: 2021
Journal: Cancer Discov
Title: LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Volume: 11
Issue: 6
Pages: 1398-1410
Publication
First Author: Shillingford JM
Year: 2003
Journal: J Histochem Cytochem
Title: Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions.
Volume: 51
Issue: 5
Pages: 555-65
Publication
First Author: Stuart E
Year: 2014
Journal: Mol Cancer Ther
Title: Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.
Volume: 13
Issue: 2
Pages: 468-74
Publication
First Author: Strobl K
Year: 2024
Journal: EMBO Mol Med
Title: JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia.
Volume: 16
Issue: 12
Pages: 3142-3168
Publication
First Author: Zhang C
Year: 2016
Journal: Immunity
Title: CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.
Volume: 44
Issue: 4
Pages: 913-923
Publication
First Author: Li J
Year: 2008
Journal: J Biol Chem
Title: Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis.
Volume: 283
Issue: 49
Pages: 34260-72
Publication
First Author: Walz C
Year: 2012
Journal: Blood
Title: Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2(V617F) in mice.
Volume: 119
Issue: 15
Pages: 3550-60
Publication
First Author: Shrestha H
Year: 2024
Journal: Cell Rep
Title: The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Volume: 43
Issue: 5
Pages: 114202
Publication
First Author: Park DS
Year: 2002
Journal: Mol Biol Cell
Title: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Volume: 13
Issue: 10
Pages: 3416-30
Publication
First Author: Choi P
Year: 2005
Journal: Genes Immun
Title: Linkage analysis of the genetic determinants of T-cell IL-4 secretion, and identification of Flj20274 as a putative candidate gene.
Volume: 6
Issue: 4
Pages: 290-7
Publication
First Author: Hao A
Year: 2005
Journal: Mol Biol Cell
Title: The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities.
Volume: 16
Issue: 4
Pages: 1569-83
Publication
First Author: Hoeve MA
Year: 2006
Journal: Eur J Immunol
Title: Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells.
Volume: 36
Issue: 3
Pages: 661-70
Publication
First Author: Gough NM
Year: 1995
Journal: Mamm Genome
Title: Localization of genes for two members of the JAK family of protein tyrosine kinases to murine chromosomes 4 and 19.
Volume: 6
Issue: 4
Pages: 247-8
Publication
First Author: Yin T
Year: 1995
Journal: J Biol Chem
Title: Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases.
Volume: 270
Issue: 35
Pages: 20497-502
Publication
First Author: Finbloom DS
Year: 1995
Journal: Cell Signal
Title: Regulation of the Jak/STAT signalling pathway.
Volume: 7
Issue: 8
Pages: 739-45
Publication
First Author: Liu ZG
Year: 1996
Journal: Nature
Title: Three distinct signalling responses by murine fibroblasts to genotoxic stress.
Volume: 384
Issue: 6606
Pages: 273-6
Publication
First Author: Hennighausen L
Year: 1997
Journal: J Biol Chem
Title: Prolactin signaling in mammary gland development.
Volume: 272
Issue: 12
Pages: 7567-9
Publication
First Author: Novotny-Diermayr V
Year: 2005
Journal: J Biol Chem
Title: Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
Volume: 280
Issue: 13
Pages: 12747-57
Publication
First Author: Hirata N
Year: 2009
Journal: Cell Immunol
Title: Selective regulation of interleukin-10 production via Janus kinase pathway in murine conventional dendritic cells.
Volume: 258
Issue: 1
Pages: 9-17
Publication
First Author: Babon JJ
Year: 2014
Journal: Biochem J
Title: The molecular regulation of Janus kinase (JAK) activation.
Volume: 462
Issue: 1
Pages: 1-13
Publication
First Author: Oppmann B
Year: 2000
Journal: Immunity
Title: Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Volume: 13
Issue: 5
Pages: 715-25
Publication
First Author: Osorio FG
Year: 2016
Journal: Nat Med
Title: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
Volume: 22
Issue: 1
Pages: 91-6
Publication
First Author: Fidler TP
Year: 2024
Journal: Nat Cardiovasc Res
Title: Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.
Volume: 3
Issue: 1
Pages: 60-75
Publication
First Author: Bell BD
Year: 2013
Journal: Nat Immunol
Title: The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Volume: 14
Issue: 4
Pages: 364-71
Publication  
First Author: Kang YA
Year: 2020
Journal: J Exp Med
Title: Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
Volume: 217
Issue: 3
Publication
First Author: Shillingford JM
Year: 2002
Journal: Mol Endocrinol
Title: Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis.
Volume: 16
Issue: 6
Pages: 1309-21
Publication
First Author: Shang L
Year: 2006
Journal: J Biol Chem
Title: The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons.
Volume: 281
Issue: 4
Pages: 1876-84
Publication
First Author: van de Wetering D
Year: 2009
Journal: Int Immunol
Title: IL-23 modulates CD56+/CD3- NK cell and CD56+/CD3+ NK-like T cell function differentially from IL-12.
Volume: 21
Issue: 2
Pages: 145-53
Publication
First Author: Pellegrini S
Year: 1997
Journal: Eur J Biochem
Title: The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).
Volume: 248
Issue: 3
Pages: 615-33
Publication
First Author: Liu KD
Year: 1998
Journal: Curr Opin Immunol
Title: JAK/STAT signaling by cytokine receptors.
Volume: 10
Issue: 3
Pages: 271-8
Publication
First Author: Proietti CJ
Year: 2009
Journal: Mol Cell Biol
Title: Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth.
Volume: 29
Issue: 5
Pages: 1249-65
Publication
First Author: Gilardi-Hebenstreit P
Year: 1992
Journal: Oncogene
Title: An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.
Volume: 7
Issue: 12
Pages: 2499-506
Publication
First Author: Poltorak A
Year: 2001
Journal: J Immunol
Title: A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.
Volume: 167
Issue: 4
Pages: 2106-11
Publication
First Author: Iseki M
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins.
Volume: 272
Issue: 1
Pages: 45-54
Publication
First Author: Riordan JD
Year: 2014
Journal: Mamm Genome
Title: Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse.
Volume: 25
Issue: 9-10
Pages: 473-86
Publication
First Author: Li J
Year: 2013
Journal: JAKSTAT
Title: JAK-STAT and bone metabolism.
Volume: 2
Issue: 3
Pages: e23930
Publication
First Author: Bhattacharyya S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation.
Volume: 108
Issue: 23
Pages: 9554-9
Publication
First Author: Lio CJ
Year: 2019
Journal: Blood
Title: Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies.
Volume: 134
Issue: 18
Pages: 1487-1497
Publication
First Author: Bhunia AK
Year: 2002
Journal: Cell
Title: PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.
Volume: 109
Issue: 2
Pages: 157-68
Publication
First Author: Imada K
Year: 2000
Journal: Mol Immunol
Title: The Jak-STAT pathway.
Volume: 37
Issue: 1-2
Pages: 1-11
Publication
First Author: Larsson-Blomberg L
Year: 1994
Journal: FEBS Lett
Title: Isolation of tyrosine kinase related genes expressed in the early hematopoietic system.
Volume: 348
Issue: 2
Pages: 119-25
Publication
First Author: Brown MP
Year: 1999
Journal: Aust N Z J Med
Title: Cytokines, Jaks, Stats, health and disease.
Volume: 29
Issue: 1
Pages: 73-8
Publication
First Author: Cheng J
Year: 2007
Journal: Cell
Title: SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia.
Volume: 131
Issue: 3
Pages: 584-95
Publication
First Author: Orvedahl A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.
Volume: 116
Issue: 33
Pages: 16497-16506
Publication
First Author: Koza RA
Year: 2000
Journal: J Biol Chem
Title: Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.
Volume: 275
Issue: 44
Pages: 34486-92
Publication  
First Author: Hung CH
Year: 2021
Journal: Int J Mol Sci
Title: A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis.
Volume: 22
Issue: 15
Publication
First Author: Ruiz JC
Year: 1994
Journal: Mech Dev
Title: Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.
Volume: 48
Issue: 3
Pages: 153-64
Publication
First Author: Kim WK
Year: 2022
Journal: Nat Commun
Title: Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes.
Volume: 13
Issue: 1
Pages: 4364
Publication
First Author: Amanai M
Year: 2006
Journal: Biol Reprod
Title: A restricted role for sperm-borne microRNAs in mammalian fertilization.
Volume: 75
Issue: 6
Pages: 877-84
Publication
First Author: Sommers CL
Year: 1995
Journal: Oncogene
Title: Murine txk: a protein tyrosine kinase gene regulated by T cell activation.
Volume: 11
Issue: 2
Pages: 245-51
Publication
First Author: Kesavan C
Year: 2007
Journal: Bone
Title: Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross.
Volume: 41
Issue: 2
Pages: 223-30
Publication  
First Author: Lei Z
Year: 2022
Journal: Front Immunol
Title: EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.
Volume: 13
Pages: 843378
Publication
First Author: Boroviak T
Year: 2014
Journal: Nat Cell Biol
Title: The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.
Volume: 16
Issue: 6
Pages: 516-28
Publication
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
HT Experiment
Series Id: GSE26188
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress