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Search results 601 to 700 out of 3295 for Kras

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Type Details Score
Publication
First Author: Nagathihalli NS
Year: 2018
Journal: Cancer Res
Title: Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
Volume: 78
Issue: 21
Pages: 6235-6246
Publication
First Author: Elangovan IM
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: FOSL1 Promotes Kras-induced Lung Cancer through Amphiregulin and Cell Survival Gene Regulation.
Volume: 58
Issue: 5
Pages: 625-635
Publication
First Author: Kim J
Year: 2016
Journal: Nature
Title: XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Volume: 538
Issue: 7623
Pages: 114-117
Publication
First Author: Ruscetti M
Year: 2016
Journal: Oncogene
Title: HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer.
Volume: 35
Issue: 29
Pages: 3781-95
Publication  
First Author: Smolinska A
Year: 2022
Journal: Cancers (Basel)
Title: DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis.
Volume: 14
Issue: 17
Publication
First Author: Keenan BP
Year: 2014
Journal: Gastroenterology
Title: A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Volume: 146
Issue: 7
Pages: 1784-94.e6
Publication
First Author: Qiu W
Year: 2016
Journal: Gastroenterology
Title: Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
Volume: 150
Issue: 1
Pages: 218-228.e12
Publication      
First Author: Jiang J
Year: 2024
Journal: Cancer Commun (Lond)
Title: Yap methylation-induced FGL1 expression suppresses anti-tumor immunity and promotes tumor progression in KRAS-driven lung adenocarcinoma.
Publication
First Author: Mollaoglu G
Year: 2018
Journal: Immunity
Title: The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Volume: 49
Issue: 4
Pages: 764-779.e9
Publication
First Author: Blasco RB
Year: 2011
Journal: Cancer Cell
Title: c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma.
Volume: 19
Issue: 5
Pages: 652-63
Publication
First Author: Cai Z
Year: 2011
Journal: Mol Cell Biol
Title: Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration.
Volume: 31
Issue: 14
Pages: 2973-83
Publication
First Author: Rädler PD
Year: 2021
Journal: Sci Rep
Title: Dual recombinase action in the normal and neoplastic mammary gland epithelium.
Volume: 11
Issue: 1
Pages: 20775
Publication
First Author: Moding EJ
Year: 2014
Journal: J Clin Invest
Title: Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium.
Volume: 124
Issue: 8
Pages: 3325-38
Publication
First Author: Barrière C
Year: 2007
Journal: Mol Oncol
Title: Mice thrive without Cdk4 and Cdk2.
Volume: 1
Issue: 1
Pages: 72-83
Publication    
First Author: Camolotto SA
Year: 2018
Journal: Elife
Title: FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.
Volume: 7
Publication
First Author: Cobo I
Year: 2023
Journal: Nat Commun
Title: NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.
Volume: 14
Issue: 1
Pages: 3761
Publication
First Author: Malkinson AM
Year: 1993
Journal: Mouse Genome
Title: Correlation of Kras-2 protooncogene structure with susceptibility to urethane-induced lung cancer in CXB recombinant inbred strains
Volume: 91
Issue: 1
Pages: 130-32
Publication
First Author: Lilis I
Year: 2019
Journal: Oncoimmunology
Title: Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.
Volume: 8
Issue: 7
Pages: 1593802
Publication
First Author: Mantilla-Rojas C
Year: 2021
Journal: Oncogene
Title: A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy.
Volume: 40
Issue: 17
Pages: 3047-3059
Publication
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
Publication
First Author: Tetteh PW
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.
Volume: 113
Issue: 42
Pages: 11859-11864
Publication
First Author: Lesina M
Year: 2016
Journal: J Clin Invest
Title: RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.
Volume: 126
Issue: 8
Pages: 2919-32
Publication
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
Publication
First Author: Zhu LY
Year: 2022
Journal: Cancer Res
Title: Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
Volume: 82
Issue: 22
Pages: 4153-4163
Publication
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
Publication
First Author: Lapouge G
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Identifying the cellular origin of squamous skin tumors.
Volume: 108
Issue: 18
Pages: 7431-6
Publication
First Author: Hendley AM
Year: 2016
Journal: Cancer Res
Title: p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.
Volume: 76
Issue: 11
Pages: 3351-63
Publication
First Author: Kinross KM
Year: 2012
Journal: J Clin Invest
Title: An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.
Volume: 122
Issue: 2
Pages: 553-7
Publication
First Author: Cammareri P
Year: 2017
Journal: Cell Death Differ
Title: TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.
Volume: 24
Issue: 10
Pages: 1681-1693
Publication
First Author: Pacheco-Pinedo EC
Year: 2011
Journal: J Clin Invest
Title: Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.
Volume: 121
Issue: 5
Pages: 1935-45
Publication
First Author: Nakagawa H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
Volume: 114
Issue: 19
Pages: E3806-E3815
Publication
First Author: Heid I
Year: 2011
Journal: Gastroenterology
Title: Early requirement of Rac1 in a mouse model of pancreatic cancer.
Volume: 141
Issue: 2
Pages: 719-30, 730.e1-7
Publication  
First Author: Gualandi M
Year: 2020
Journal: Life Sci Alliance
Title: Oncogenic ALK F1174L drives tumorigenesis in cutaneous squamous cell carcinoma.
Volume: 3
Issue: 6
Publication
First Author: Rosenfeldt MT
Year: 2013
Journal: Nature
Title: p53 status determines the role of autophagy in pancreatic tumour development.
Volume: 504
Issue: 7479
Pages: 296-300
Publication
First Author: Park J
Year: 2020
Journal: Cancer Res
Title: YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice.
Volume: 80
Issue: 21
Pages: 4768-4779
Publication
First Author: Van Mater D
Year: 2015
Journal: Cancer Res
Title: Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.
Volume: 75
Issue: 3
Pages: 605-14
Publication
First Author: Xu H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.
Volume: 115
Issue: 16
Pages: 4228-4233
Publication
First Author: Zhang W
Year: 2014
Journal: Sci Signal
Title: Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 324
Pages: ra42
Publication
First Author: Ren YA
Year: 2016
Journal: Cancer Res
Title: Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones.
Volume: 76
Issue: 8
Pages: 2206-18
Publication
First Author: Ma L
Year: 2017
Journal: PLoS One
Title: LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Volume: 12
Issue: 5
Pages: e0176844
Publication
First Author: Collisson EA
Year: 2012
Journal: Cancer Discov
Title: A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.
Volume: 2
Issue: 8
Pages: 685-93
Publication
First Author: Maniati E
Year: 2011
Journal: J Clin Invest
Title: Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
Volume: 121
Issue: 12
Pages: 4685-99
Publication  
First Author: Tu B
Year: 2019
Journal: JCI Insight
Title: YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma.
Volume: 4
Issue: 21
Publication
First Author: Mace TA
Year: 2015
Journal: Oncotarget
Title: Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Volume: 6
Issue: 42
Pages: 44509-22
Publication
First Author: Baumgart S
Year: 2014
Journal: Cancer Discov
Title: Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Volume: 4
Issue: 6
Pages: 688-701
Publication
First Author: Malkinson AM
Year: 1998
Journal: Exp Lung Res
Title: Molecular comparison of human and mouse pulmonary adenocarcinomas.
Volume: 24
Issue: 4
Pages: 541-55
Publication
First Author: Principe DR
Year: 2017
Journal: Oncogene
Title: TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.
Volume: 36
Issue: 30
Pages: 4336-4348
Publication
First Author: Tang J
Year: 2019
Journal: Lab Invest
Title: Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Volume: 99
Issue: 10
Pages: 1454-1469
Publication
First Author: Winslow MM
Year: 2011
Journal: Nature
Title: Suppression of lung adenocarcinoma progression by Nkx2-1.
Volume: 473
Issue: 7345
Pages: 101-4
Publication
First Author: Chen Z
Year: 2012
Journal: Nature
Title: A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Volume: 483
Issue: 7391
Pages: 613-7
Publication
First Author: To MD
Year: 2013
Journal: Oncogene
Title: Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Volume: 32
Issue: 34
Pages: 4028-33
Publication
First Author: Kaneta Y
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Loss of Pancreatic E-Cadherin Causes Pancreatitis-Like Changes and Contributes to Carcinogenesis.
Volume: 9
Issue: 1
Pages: 105-119
Publication
First Author: Hruban RH
Year: 2006
Journal: Cancer Res
Title: Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Volume: 66
Issue: 1
Pages: 95-106
Publication
First Author: Ancey PB
Year: 2021
Journal: Cancer Res
Title: GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.
Volume: 81
Issue: 9
Pages: 2345-2357
Publication
First Author: Shrestha H
Year: 2024
Journal: Cell Rep
Title: The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Volume: 43
Issue: 5
Pages: 114202
Publication
First Author: Lahtela J
Year: 2015
Journal: Dis Model Mech
Title: The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis.
Volume: 8
Issue: 4
Pages: 393-401
Publication
First Author: Chen S
Year: 2022
Journal: Cancer Discov
Title: Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Volume: 12
Issue: 10
Pages: 2434-2453
Publication
First Author: Mann KM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.
Volume: 109
Issue: 16
Pages: 5934-41
Publication  
First Author: Fernandes LM
Year: 2023
Journal: Front Cell Dev Biol
Title: Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function.
Volume: 11
Pages: 1276333
Publication
First Author: Chalabi-Dchar M
Year: 2015
Journal: Gastroenterology
Title: Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Volume: 148
Issue: 7
Pages: 1452-65
Publication
First Author: Armacki M
Year: 2020
Journal: Gastroenterology
Title: Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice.
Volume: 159
Issue: 3
Pages: 1019-1035.e22
Publication
First Author: He P
Year: 2018
Journal: Gastroenterology
Title: Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.
Volume: 154
Issue: 5
Pages: 1494-1508.e13
Publication
First Author: Navas C
Year: 2012
Journal: Cancer Cell
Title: EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 3
Pages: 318-30
Publication
First Author: Han L
Year: 2023
Journal: Nat Commun
Title: The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Volume: 14
Issue: 1
Pages: 1
Publication
First Author: Drosten M
Year: 2017
Journal: Cancer Res
Title: H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences.
Volume: 77
Issue: 3
Pages: 707-718
Publication
First Author: Badgley MA
Year: 2020
Journal: Science
Title: Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Volume: 368
Issue: 6486
Pages: 85-89
Publication
First Author: Sakai E
Year: 2018
Journal: Cancer Res
Title: Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Volume: 78
Issue: 5
Pages: 1334-1346
Publication
First Author: Gruber R
Year: 2016
Journal: Gastroenterology
Title: YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.
Volume: 151
Issue: 3
Pages: 526-39
Publication
First Author: Kimura Y
Year: 2018
Journal: Gastroenterology
Title: ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Volume: 155
Issue: 1
Pages: 194-209.e2
Publication
First Author: Mullany LK
Year: 2011
Journal: Oncogene
Title: Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.
Volume: 30
Issue: 32
Pages: 3522-36
Publication
First Author: Schmit F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.
Volume: 111
Issue: 17
Pages: 6395-400
Publication
First Author: Morran DC
Year: 2014
Journal: Gut
Title: Targeting mTOR dependency in pancreatic cancer.
Volume: 63
Issue: 9
Pages: 1481-9
Publication
First Author: Wu CY
Year: 2014
Journal: Gastroenterology
Title: PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Volume: 147
Issue: 6
Pages: 1405-16.e7
Publication
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
Publication
First Author: Shrestha A
Year: 2019
Journal: Cell Mol Life Sci
Title: A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development.
Volume: 76
Issue: 14
Pages: 2817-2832
Publication
First Author: Ocal O
Year: 2015
Journal: Dis Model Mech
Title: A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
Volume: 8
Issue: 10
Pages: 1201-11
Publication
First Author: Görgülü K
Year: 2019
Journal: Gastroenterology
Title: Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
Volume: 156
Issue: 1
Pages: 203-217.e20
Publication
First Author: Pearson HB
Year: 2011
Journal: J Clin Invest
Title: SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Volume: 121
Issue: 11
Pages: 4257-67
Publication
First Author: Cai Z
Year: 2014
Journal: Dev Dyn
Title: Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesis.
Volume: 243
Issue: 10
Pages: 1310-6
Publication
First Author: Li H
Year: 2014
Journal: J Cell Sci
Title: Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Volume: 127
Issue: Pt 3
Pages: 571-82
Publication
First Author: Tammela T
Year: 2017
Journal: Nature
Title: A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Volume: 545
Issue: 7654
Pages: 355-359
Publication
First Author: Farago AF
Year: 2012
Journal: Cell
Title: SnapShot: Lung cancer models.
Volume: 149
Issue: 1
Pages: 246-246.e1
Publication
First Author: Hessmann E
Year: 2016
Journal: Oncogene
Title: MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.
Volume: 35
Issue: 13
Pages: 1609-18
Publication
First Author: Chang DR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Lung epithelial branching program antagonizes alveolar differentiation.
Volume: 110
Issue: 45
Pages: 18042-51
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory