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Search results 601 to 700 out of 749 for Lmna

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Type Details Score
Allele
Lmna<em2Smoc> | MGI:7290845
Name: lamin A; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Lmna<tm1Lgf> | MGI:3587791
Name: lamin A; targeted mutation 1, Loren G Fong
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lmna<tm5Lgf> | MGI:4457607
Name: lamin A; targeted mutation 5, Loren G Fong
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lmna<em1Gpt> | MGI:6781726
Name: lamin A; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Strain
MGI:6475698 | C57BL/6JSmoc-Lmna<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Lmna<em3Smoc> | MGI:7290846
Name: lamin A; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lmna<tm3Stw> | MGI:3588578
Name: lamin A; targeted mutation 3, Colin L Stewart
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Tg(Myh6-LMNA*E82K)35Lizh | MGI:5907285
Name: transgene insertion 35, Lianfeng Zhang
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Lmna<tm6Lgf> | MGI:4457608
Name: lamin A; targeted mutation 6, Loren G Fong
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:7623419 | C57BL/6JSmoc-Lmna<em3Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Coding Gene
MGI:2143886 | Dot1l
Type: protein_coding_gene
Organism: mouse, laboratory
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Transgene
MGI:5907284 | Tg(Myh6-LMNA*E82K)35Lizh
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129S1/Sv * 129S4/SvJaeSor * C57BL
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dot1l/Dot1l Tg(Myhca-cre)1Abel/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-LMNA*E82K)35Lizh/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0070370 | restrictive dermopathy 2
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Allele
Lmna<em1Smoc> | MGI:7290844
Name: lamin A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Allele
Lmna<tm1Gbon> | MGI:3527206
Name: lamin A; targeted mutation 1, Gisele Bonne
Allele Type: Targeted
Attribute String: Humanized sequence
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DO Term
DOID:0070247 | autosomal dominant Emery-Dreifuss muscular dystrophy 2
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DO Term
DOID:0070248 | autosomal recessive Emery-Dreifuss muscular dystrophy 3
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DO Term
DOID:0111584 | dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
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Allele
Lmna<tm1(LMNA)Cya> | MGI:7657294
Name: lamin A; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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HT Experiment
GSE190977 | TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Zmpste24<tm1Sgy> | MGI:2158363
Name: zinc metallopeptidase, STE24; targeted mutation 1, Steven G Young
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lmna<tm2Stw> | MGI:2662836
Name: lamin A; targeted mutation 2, Colin L Stewart
Allele Type: Targeted
Attribute String: Humanized sequence, Hypomorph
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Allele
Sirt6<tm1Fwa> | MGI:3686893
Name: sirtuin 6; targeted mutation 1, Frederick W Alt
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer | MGI:3834666
Name: transgene insertion VF1-07, Maria Eriksson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence, Reporter
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Allele
Lmna<tm8Lgf> | MGI:4868581
 
Name: lamin A; targeted mutation 8, Loren G Fong
Allele Type: Targeted
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Allele
Lmna<tm1.1Otin> | MGI:5295747
Name: lamin A; targeted mutation 1.1, Carlos Lopez-Otin
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Tg(LMNA*G608G)HClns | MGI:5441745
Name: transgene insertion H, Francis Collins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Lmna<tm12Lgf> | MGI:5806143
Name: lamin A; targeted mutation 12, Loren G Fong
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Lmna<tm1Bliu> | MGI:6423595
Name: lamin A; targeted mutation 1, Baohua Liu
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Lmna<tm1.1Bliu> | MGI:6423596
Name: lamin A; targeted mutation 1.1, Baohua Liu
Allele Type: Targeted
Attribute String: Humanized sequence, Modified isoform(s)
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Allele
Vcpip1<em1Zlou> | MGI:6515598
Name: valosin containing protein (p97)/p47 complex interacting protein 1; endonuclease-mediated mutation 1, Zhenkun Lou
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lmna<em1Fenz> | MGI:7518551
Name: lamin A; endonuclease-mediated mutation 1, Fenping Zheng
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(Lmna-EGFP)PE184Gsat | MGI:5051747
Name: transgene insertion PE184, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6475697 | C57BL/6JSmoc-Lmna<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7657658 | C57BL/6N-Lmna<tm1(LMNA)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
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Protein Coding Gene
MGI:1917925 | Vcpip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1354161 | Sirt6
Type: protein_coding_gene
Organism: mouse, laboratory
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Transgene
MGI:3834664 | Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer
Type: transgene
Organism: mouse, laboratory
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Allele
Lmna<Dhe> | MGI:3848037
 
Name: lamin A; disheveled hair and ears
Allele Type: Spontaneous
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Transgene
MGI:5441744 | Tg(LMNA*G608G)HClns
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zmpste24/Zmpste24
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zmpste24/Zmpste24
Background: B6.129S4-Zmpste24
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sirt6/Sirt6
Background: involves: 129S6/SvEvTac * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(KRT5-tTA)1216Glk/? Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zmpste24/Zmpste24
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(LMNA*G608G)HClns/?
Background: C57BL/6-Tg(LMNA*G608G)HClns/J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:3911 | progeria
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna Tg(Tek-cre)1Ywa/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vcpip1/Vcpip1
Background: C57BL/6NHsd-Vcpip1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+> Nat10/Nat10<+>
Background: involves: 129P2/OlaHsd * C57BL/6NTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna Nat10/Nat10<+>
Background: involves: 129P2/OlaHsd * C57BL/6NTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129P2/OlaHsd * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: C57BL/6-Lmna
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0070202 | familial partial lipodystrophy type 2
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Strain
MGI:5654004 | (C57BL/6 x 129P2/OlaHsd-Lmna<tm1Lgf>)F1
Attribute String: F1 hybrid
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Allele
Lmna<tm4Lgf> | MGI:3837135
Name: lamin A; targeted mutation 4, Loren G Fong
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lmna<tm9Lgf> | MGI:5571496
Name: lamin A; targeted mutation 9, Loren G Fong
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Lmna<tm10Lgf> | MGI:5571497
Name: lamin A; targeted mutation 10, Loren G Fong
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Lmna<tm11Lgf> | MGI:5752218
 
Name: lamin A; targeted mutation 11, Loren G Fong
Allele Type: Targeted
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+> Zmpste24/Zmpste24
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna Zmpste24/Zmpste24
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna Zmpste24/Zmpste24
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Allele
Lmna<tm1Stw> | MGI:2177930
Name: lamin A; targeted mutation 1, Colin L Stewart
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Zmpste24<tm1Otin> | MGI:2180033
Name: zinc metallopeptidase, STE24; targeted mutation 1, Carlos Lopez-Otin
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
Background: NOD.Cg-H2-Ab1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: B6(D2)-Lmna/TyGrsrJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:1890508 | Zmpste24
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
E-MTAB-13678 | Endothelial YAP/TAZ activation is a key mediator of atherosclerosis in Hutchinson-Gilford progeria syndrome
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Lmna/Lmna
Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lmna/Lmna Zmpste24/Zmpste24
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Gene
2688 | GH1
Type: gene
Organism: human
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Publication
32196928 | J:287545
First Author: Griveau A
Year: 2020
Journal: Aging Cell
Title: The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes.
Volume: 19
Issue: 4
Pages: e13122
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Publication
35027552 | J:321295
First Author: Czapiewski R
Year: 2022
Journal: Nat Commun
Title: Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy.
Volume: 13
Issue: 1
Pages: 321
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Publication
33536248 | J:303793
 
First Author: Kronenberg-Tenga R
Year: 2021
Journal: J Cell Sci
Title: A lamin A/C variant causing striated muscle disease provides insights into filament organization.
Volume: 134
Issue: 6
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Protein Coding Gene
MGI:1916892 | Mlip
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0032453 | -
Type: protein_coding_gene
Organism: Mus caroli
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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