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Search results 601 to 700 out of 893 for Lyn

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Type Details Score
Publication
32720892 | J:294233
   
First Author: Blumenthal D
Year: 2020
Journal: Elife
Title: Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex.
Volume: 9
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Publication
7594458 | -
First Author: Johnson SA
Year: 1995
Journal: J Immunol
Title: Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases.
Volume: 155
Issue: 10
Pages: 4596-603
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Genotype
Genotype
Symbol: Il4/Il4 Lyn/Lyn
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
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Allele
Lyn<+> | MGI:2182294
 
Name: LYN proto-oncogene, Src family tyrosine kinase; wild type
Allele Type: Not Specified
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Allele
Hcls1<+> | MGI:2433243
   
Name: hematopoietic cell specific Lyn substrate 1; wild type
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Allele
Lyn<mld4> | MGI:3832561
 
Name: LYN proto-oncogene, Src family tyrosine kinase; multilineage defect 4
Allele Type: Chemically induced (ENU)
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Strain
MGI:3837221 | C57BL/6-Lyn<weeb>
Attribute String: coisogenic, chemically induced mutation
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Strain
MGI:4821156 | C57BL/6-Lyn<weeb>/Mmucd
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Allele
Lyn<M2Btlr> | MGI:5613173
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Lyn<M3Btlr> | MGI:5806331
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6-Lyn
Zygosity: hm
Has Mutant Allele: true
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Publication
10748115 | -
First Author: Gaul BS
Year: 2000
Journal: J Biol Chem
Title: Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor.
Volume: 275
Issue: 21
Pages: 16174-82
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Publication
15795233 | -
First Author: Brunati AM
Year: 2005
Journal: J Biol Chem
Title: Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein.
Volume: 280
Issue: 22
Pages: 21029-35
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Publication
10590261 | J:64960
First Author: Takemoto Y
Year: 1999
Journal: Int Immunol
Title: Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.
Volume: 11
Issue: 12
Pages: 1957-64
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Publication
10754317 | J:123433
First Author: Igietseme JU
Year: 2000
Journal: J Immunol
Title: Suppression of endogenous IL-10 gene expression in dendritic cells enhances antigen presentation for specific Th1 induction: potential for cellular vaccine development.
Volume: 164
Issue: 8
Pages: 4212-9
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Publication
8649453 | J:33480
First Author: Truneh A
Year: 1996
Journal: Mol Immunol
Title: Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis.
Volume: 33
Issue: 3
Pages: 321-34
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Publication
18768859 | J:139097
First Author: He Q
Year: 2008
Journal: J Immunol
Title: Involvement of LEK1 in dendritic cell regulation of T cell immunity against Chlamydia.
Volume: 181
Issue: 6
Pages: 4037-42
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Publication
20530793 | J:166491
First Author: Scielzo C
Year: 2010
Journal: Blood
Title: HS1 has a central role in the trafficking and homing of leukemic B cells.
Volume: 116
Issue: 18
Pages: 3537-46
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Publication
8168489 | J:17868
First Author: Clark MR
Year: 1994
Journal: EMBO J
Title: Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.
Volume: 13
Issue: 8
Pages: 1911-9
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Publication
7628441 | J:243407
First Author: Takemoto Y
Year: 1995
Journal: EMBO J
Title: LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck.
Volume: 14
Issue: 14
Pages: 3403-14
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Publication
9058808 | J:57557
First Author: Suzuki Y
Year: 1997
Journal: J Immunol
Title: HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.
Volume: 158
Issue: 6
Pages: 2736-44
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Publication
21398607 | J:172457
First Author: Dehring DA
Year: 2011
Journal: J Immunol
Title: Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells.
Volume: 186
Issue: 8
Pages: 4805-18
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Genotype
Genotype
Symbol: Kit/Kit Lyn/Lyn
Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
Zygosity: cx
Has Mutant Allele: true
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Publication
10327049 | -
First Author: Maeda A
Year: 1999
Journal: Oncogene
Title: Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1.
Volume: 18
Issue: 14
Pages: 2291-7
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Strain
MGI:6331748 | B6;129-Lyn<tm1Ard> Tg(IghelMD4)4Ccg/AnuApb
Attribute String: mutant strain, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Lyn/Lyn Tg(IghelMD4)4Ccg/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn<+>
Background: C57BL/6J-Lyn
Zygosity: ht
Has Mutant Allele: true
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GO Term
GO:0034996 | RasGAP-Fyn-Lyn-Yes complex
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Allele
Lyn<tm1Sor> | MGI:1861966
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Philippe Soriano
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lyn<tm1Mhi> | MGI:2157016
 
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Margaret Hibbs
Allele Type: Targeted
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Allele
Lyn<tm1Tya> | MGI:2386196
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Tadashi Yamamoto
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Hcls1<tm1Wtn> | MGI:3623117
Name: hematopoietic cell specific Lyn substrate 1; targeted mutation 1, Takeshi Watanabe
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Hcls1<tm2Wtn> | MGI:3623118
Name: hematopoietic cell specific Lyn substrate 1; targeted mutation 2, Takeshi Watanabe
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Hcls1<tm1a(KOMP)Wtsi> | MGI:4363481
Name: hematopoietic cell specific Lyn substrate 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Hcls1<tm1e(KOMP)Wtsi> | MGI:4363408
Name: hematopoietic cell specific Lyn substrate 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<tm1(NCOM)Mfgc> | MGI:4880547
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<tm1e(EUCOMM)Hmgu> | MGI:4888892
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lyn<tm1a(EUCOMM)Hmgu> | MGI:4888900
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Hcls1<Gt(353E2)Cmhd> | MGI:4952128
 
Name: hematopoietic cell specific Lyn substrate 1; gene trap 353E2, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Lyn<m1Anu> | MGI:5501039
 
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 1, Australian National University
Allele Type: Chemically induced (ENU)
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Allele
Lyn<tm1.1Calo> | MGI:5545812
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1.1 Clifford A Lowell
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Lyn<m2Anu> | MGI:5563397
 
Name: LYN proto-oncogene, Src family tyrosine kinase; mutation 2, Australian National University
Allele Type: Chemically induced (ENU)
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Strain
MGI:5613337 | C57BL/6J-Lyn<M2Btlr>
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Allele
Lyn<tm1b(EUCOMM)Hmgu> | MGI:5756074
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5807131 | C57BL/6J-Lyn<M3Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Allele
Hcls1<em13Gpt> | MGI:7300162
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 13, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hcls1<em1Gpt> | MGI:7300163
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em1Gpt> | MGI:7301855
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em2Gpt> | MGI:7301856
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hcls1<em1Smoc> | MGI:7290170
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hcls1<em1(IMPC)Ccpcz> | MGI:7425737
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lyn<em1Fret> | MGI:7513892
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Tanya S Freedman
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Allele
Lyn<em2Fret> | MGI:7513895
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, Tanya S Freedman
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Allele
Hcls1<em1Cya> | MGI:7584250
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hcls1<em2Cya> | MGI:7584251
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em2Cya> | MGI:7584898
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em1Smoc> | MGI:7626627
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hcls1<em3Cya> | MGI:7793809
Name: hematopoietic cell specific Lyn substrate 1; endonuclease-mediated mutation 3, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lyn<em1Cya> | MGI:7794431
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Publication
12898452 | J:120672
First Author: Moore T
Year: 2003
Journal: J Infect Dis
Title: Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens.
Volume: 188
Issue: 4
Pages: 617-24
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Publication
23201171 | J:196794
 
First Author: He Q
Year: 2013
Journal: J Steroid Biochem Mol Biol
Title: Chlamydial infection in vitamin D receptor knockout mice is more intense and prolonged than in wild-type mice.
Volume: 135
Pages: 7-14
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Genotype
Genotype
Symbol: Igh-7/Igh-7 Lyn/Lyn
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Publication
7506729 | J:16376
First Author: Fukamachi H
Year: 1994
Journal: J Immunol
Title: Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fc epsilon RI cross-linking.
Volume: 152
Issue: 2
Pages: 642-52
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Strain
MGI:5654872 | either: B6.129-Lyn<tm1Ard> Fyn<tm1Sor> Blk<tm1Tara> or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
Attribute String: Not specified
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Genotype
Genotype
Symbol: Blk/Blk Fyn/Fyn Lyn/Lyn
Background: either: B6.129-Lyn Fyn Blk or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn<+> Tg(IghelMD4)4Ccg/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
20644716 | -
First Author: Peirce MJ
Year: 2010
Journal: PLoS One
Title: Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.
Volume: 5
Issue: 7
Pages: e11465
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Publication
19917685 | J:157515
First Author: Carrizosa E
Year: 2009
Journal: J Immunol
Title: Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreading.
Volume: 183
Issue: 11
Pages: 7352-61
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Publication
12709437 | -
First Author: Maeno K
Year: 2003
Journal: J Biol Chem
Title: Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.
Volume: 278
Issue: 27
Pages: 24912-20
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Publication
18985015 | -
First Author: Cho NH
Year: 2008
Journal: Exp Mol Med
Title: Multi-transmembrane protein K15 of Kaposi's sarcoma-associated herpesvirus targets Lyn kinase in the membrane raft and induces NFAT/AP1 activities.
Volume: 40
Issue: 5
Pages: 565-73
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Publication
24447079 | -
First Author: Ryan JJ
Year: 2014
Journal: Clin Exp Allergy
Title: Too much of a good thing: beta-chain overexpression blocks FcεRI signalling by capturing Lyn in the cytosol.
Volume: 44
Issue: 2
Pages: 154-6
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Publication
22364282 | -
First Author: Whiting RJ
Year: 2012
Journal: Biochem J
Title: Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1.
Volume: 442
Issue: 3
Pages: 611-20
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Publication
33475496 | J:300832
   
First Author: Wagstaff LJ
Year: 2021
Journal: Elife
Title: Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Volume: 10
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Strain
MGI:3785470 | B6.129S4-Lyn<tm1Sor>
Attribute String: congenic, targeted mutation
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Strain
MGI:2174360 | 129/Sv-Lyn<tm1Sor>/J
Attribute String: mutant strain, targeted mutation
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Strain
MGI:2165087 | B6.129S4-Lyn<tm1Sor>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6331938 | B6.129S1-Lyn<tm1Mhi>/LudApb
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:7386767 | B6.129P2-Lyn<tm1Tya>/Tya
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6143084 | C57BL/6N-A<tm1Brd>/a Lyn<tm1a(EUCOMM)Hmgu>/HMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:6121866 | C57BL/6N-Lyn<tm1a(EUCOMM)Hmgu>/H
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5694951 | C57BL/6JAnu-Lyn<m1Anu>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Strain
MGI:6332056 | C57BL/6JAnu-Lyn<m1Anu>/AnuApb
Attribute String: mutant strain, coisogenic
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Strain
MGI:6343651 | C57BL/6J-Lyn<m1Anu>/Mmucd
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Strain
MGI:5564691 | B6(SB)-Lyn<m2Anu>/AnuApb
Attribute String: chemically induced mutation, mutant strain, congenic
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Strain
MGI:5648480 | C57B/6JAnu-Lyn<m2Anu>/AnuApb
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Strain
MGI:6143684 | B6(SB)-Lyn<m2Anu>/Mmucd
Attribute String: mutant strain, congenic, chemically induced mutation
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Strain
MGI:6260791 | C57BL/6N-Lyn<tm1b(EUCOMM)Hmgu>/H
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6768015 | C57BL/6JGpt-Hcls1<em13Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6768016 | C57BL/6JGpt-Hcls1<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6475486 | C57BL/6JSmoc-Hcls1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7628771 | C57BL/6NCrl-Hcls1<em1(IMPC)Ccpcz>/Ccpcz
Attribute String: coisogenic
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Strain
MGI:7853556 | C57BL/6NCrl-Hcls1<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7593173 | C57BL/6J-Hcls1<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7588489 | C57BL/6J-Hcls1<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7590474 | C57BL/6J-Lyn<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6429137 | C57BL/6JSmoc-Lyn<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7836377 | C57BL/6JCya-Hcls1<em3Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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