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Search results 601 to 700 out of 3733 for Mak

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Type Details Score
Publication
14978084 | J:88234
First Author: Khanolkar A
Year: 2004
Journal: J Immunol
Title: CD4 T cell-dependent CD8 T cell maturation.
Volume: 172
Issue: 5
Pages: 2834-44
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Publication
20308634 | J:160485
First Author: Dispirito JR
Year: 2010
Journal: J Immunol
Title: Histone acetylation at the single-cell level: a marker of memory CD8+ T cell differentiation and functionality.
Volume: 184
Issue: 9
Pages: 4631-6
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Publication
7737281 | J:112983
First Author: Heemskerk MH
Year: 1995
Journal: Eur J Immunol
Title: Activation of virus-specific major histocompatibility complex class II-restricted CD8+ cytotoxic T cells in CD4-deficient mice.
Volume: 25
Issue: 4
Pages: 1109-12
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Publication
16339521 | J:122220
First Author: Lunsford KE
Year: 2005
Journal: J Immunol
Title: Targeting LFA-1 and cd154 suppresses the in vivo activation and development of cytolytic (cd4-Independent) CD8+ T cells.
Volume: 175
Issue: 12
Pages: 7855-66
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Publication
15845865 | J:110969
First Author: Joetham A
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Airway hyperresponsiveness in the absence of CD4+ T cells after primary but not secondary challenge.
Volume: 33
Issue: 1
Pages: 89-96
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Publication
34220551 | J:309587
 
First Author: Gokina NI
Year: 2021
Journal: Front Physiol
Title: Deficiency in CD4 T Cells Leads to Enhanced Postpartum Internal Carotid Artery Vasoconstriction in Mice: The Role of Nitric Oxide.
Volume: 12
Pages: 686429
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Publication
32404525 | J:290222
 
First Author: Chakravarty D
Year: 2020
Journal: J Virol
Title: CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation.
Volume: 94
Issue: 14
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Publication
20849916 | J:167253
First Author: Fenster CP
Year: 2010
Journal: Neurosci Lett
Title: The role of CD4-dependent signaling in interleukin-16 induced c-Fos expression and facilitation of neurite outgrowth in cerebellar granule neurons.
Volume: 485
Issue: 3
Pages: 212-6
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Publication
16002566 | J:104787
First Author: Caldwell CC
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion.
Volume: 289
Issue: 5
Pages: G969-76
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Publication
17334223 | J:134164
First Author: Kim DK
Year: 2007
Journal: Exp Mol Med
Title: A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice.
Volume: 39
Issue: 1
Pages: 1-7
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Publication
16877409 | J:112225
First Author: Lepisto AJ
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: CD8 T cells mediate transient herpes stromal keratitis in CD4-deficient mice.
Volume: 47
Issue: 8
Pages: 3400-9
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Allele
Cd8a<tm1Mak> | MGI:1857149
Name: CD8 subunit alpha; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:2162616 | B6.129S2-Cd28<tm1Mak>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4889104 | B6.129S2-Cd28<tm1Mak>/ThwAnuApb
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4453588 | B6.129S2-Cd28<tm1Mak>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3620228 | NOD.129S2-Cd28<tm1Mak>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2663283 | NOD.129S2(B6)-Cd28<tm1Mak>/JbsJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2162009 | C.129S2(B6)-Cd28<tm1Mak>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7610750 | B6;129S2-Cd28<tm1Mak>/Rbrc
Attribute String: mutant stock, targeted mutation
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Publication
8943384 | J:37043
First Author: Kondo S
Year: 1996
Journal: J Immunol
Title: Contribution of the CD28 molecule to allergic and irritant-induced skin reactions in CD28 -/- mice.
Volume: 157
Issue: 11
Pages: 4822-9
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Publication
21530327 | J:172609
First Author: Yao S
Year: 2011
Journal: Immunity
Title: B7-h2 is a costimulatory ligand for CD28 in human.
Volume: 34
Issue: 5
Pages: 729-40
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Publication
15100324 | J:89694
First Author: Holsti MA
Year: 2004
Journal: J Immunol
Title: Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway.
Volume: 172
Issue: 9
Pages: 5774-81
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Publication
11238622 | J:126654
First Author: Harada Y
Year: 2001
Journal: J Immunol
Title: Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo.
Volume: 166
Issue: 6
Pages: 3797-803
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Publication
19050251 | J:142073
First Author: Freitas do Rosário AP
Year: 2008
Journal: J Immunol
Title: Gradual decline in malaria-specific memory T cell responses leads to failure to maintain long-term protective immunity to Plasmodium chabaudi AS despite persistence of B cell memory and circulating antibody.
Volume: 181
Issue: 12
Pages: 8344-55
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Publication
37593744 | J:347989
 
First Author: Obarorakpor N
Year: 2023
Journal: Front Immunol
Title: Regulatory T cells targeting a pathogenic MHC class II: Insulin peptide epitope postpone spontaneous autoimmune diabetes.
Volume: 14
Pages: 1207108
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Publication
14501867 | J:126214
First Author: Habiro K
Year: 2003
Journal: Transplantation
Title: Mechanism of allorecognition and skin graft rejection in CD28 and CD40 ligand double-deficient mice.
Volume: 76
Issue: 5
Pages: 854-8
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Publication
- | J:12098
 
First Author: Chakravarti S
Year: 1991
Journal: Am J Hum Genet
Title: Assignment of the gene for perlecan to mouse chromosome 4
Volume: 49 (suppl)
Pages: 338 (Abstr.)
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Publication
11350825 | J:114405
First Author: Burr JS
Year: 2001
Journal: Am J Respir Cell Mol Biol
Title: CD28 and CTLA4 coordinately regulate airway inflammatory cell recruitment and T-helper cell differentiation after inhaled allergen.
Volume: 24
Issue: 5
Pages: 563-8
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Publication
16239547 | J:104193
First Author: van der Graaf CA
Year: 2005
Journal: Infect Immun
Title: Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae.
Volume: 73
Issue: 11
Pages: 7458-64
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Publication
11238558 | J:120551
First Author: Chitnis T
Year: 2001
Journal: J Clin Invest
Title: CD28-independent induction of experimental autoimmune encephalomyelitis.
Volume: 107
Issue: 5
Pages: 575-83
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Publication
12515810 | J:109348
First Author: Vacchio MS
Year: 2003
Journal: J Exp Med
Title: CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells.
Volume: 197
Issue: 1
Pages: 19-26
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Publication
9414285 | J:45067
First Author: Geldhof AB
Year: 1998
Journal: Blood
Title: Interleukin-12-activated natural killer cells recognize B7 costimulatory molecules on tumor cells and autologous dendritic cells.
Volume: 91
Issue: 1
Pages: 196-206
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Publication
11937552 | J:126189
First Author: Kim IJ
Year: 2002
Journal: J Immunol
Title: Antibody-mediated control of persistent gamma-herpesvirus infection.
Volume: 168
Issue: 8
Pages: 3958-64
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Publication
11086053 | J:118025
First Author: Cannons JL
Year: 2000
Journal: J Immunol
Title: Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response.
Volume: 165
Issue: 11
Pages: 6193-204
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Publication
31885821 | J:292418
 
First Author: Cong P
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD28 Deficiency Ameliorates Thoracic Blast Exposure-Induced Oxidative Stress and Apoptosis in the Brain through the PI3K/Nrf2/Keap1 Signaling Pathway.
Volume: 2019
Pages: 8460290
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Publication
8898959 | J:112979
First Author: King CL
Year: 1996
Journal: Eur J Immunol
Title: CD28-deficient mice generate an impaired Th2 response to Schistosoma mansoni infection.
Volume: 26
Issue: 10
Pages: 2448-55
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Publication
11801669 | J:127289
First Author: Compton HL
Year: 2002
Journal: J Immunol
Title: CD28 costimulation and parasite dose combine to influence the susceptibility of BALB/c mice to infection with Leishmania major.
Volume: 168
Issue: 3
Pages: 1302-8
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Publication
10477605 | J:119601
First Author: Reichmann G
Year: 1999
Journal: J Immunol
Title: The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology.
Volume: 163
Issue: 6
Pages: 3354-62
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Publication
10415032 | J:119606
First Author: Leung BL
Year: 1999
Journal: J Immunol
Title: TCR alpha beta-independent CD28 signaling and costimulation require non-CD4-associated Lck.
Volume: 163
Issue: 3
Pages: 1334-41
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Publication
11837936 | J:113015
First Author: Boone DL
Year: 2002
Journal: Inflamm Bowel Dis
Title: Interleukin-2-deficient mice develop colitis in the absence of CD28 costimulation.
Volume: 8
Issue: 1
Pages: 35-42
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Publication
18354182 | J:132988
First Author: Suzuki T
Year: 2008
Journal: J Immunol
Title: Induction of antitumor immune response by homeostatic proliferation and CD28 signaling.
Volume: 180
Issue: 7
Pages: 4596-605
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Publication
16495554 | J:107388
First Author: Honstettre A
Year: 2006
Journal: Infect Immun
Title: Role for the CD28 molecule in the control of Coxiella burnetii infection.
Volume: 74
Issue: 3
Pages: 1800-8
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Publication
11908941 | J:119134
First Author: Girvin AM
Year: 2002
Journal: J Autoimmun
Title: CD40/CD40L interaction is essential for the induction of EAE in the absence of CD28-mediated co-stimulation.
Volume: 18
Issue: 2
Pages: 83-94
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Publication
12193694 | J:120690
First Author: Gray Parkin K
Year: 2002
Journal: J Immunol
Title: Expression of CD28 by bone marrow stromal cells and its involvement in B lymphopoiesis.
Volume: 169
Issue: 5
Pages: 2292-302
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Publication
23966623 | J:205860
First Author: Byrum JN
Year: 2013
Journal: J Immunol
Title: CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts.
Volume: 191
Issue: 6
Pages: 3073-81
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Publication
11861872 | J:74756
First Author: Lee BJ
Year: 2002
Journal: J Virol
Title: CD28(-/-) mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68.
Volume: 76
Issue: 6
Pages: 3049-53
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Publication
11145712 | J:66855
First Author: Hazlett LD
Year: 2001
Journal: J Immunol
Title: B7/CD28 costimulation is critical in susceptibility to Pseudomonas aeruginosa corneal infection: a comparative study using monoclonal antibody blockade and CD28-deficient mice.
Volume: 166
Issue: 2
Pages: 1292-9
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Publication
12496383 | J:135141
First Author: Gärdby E
Year: 2003
Journal: J Immunol
Title: Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant.
Volume: 170
Issue: 1
Pages: 55-63
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Publication
10510372 | J:119231
First Author: Yin D
Year: 1999
Journal: J Immunol
Title: Ligation of CD28 in vivo induces CD40 ligand expression and promotes B cell survival.
Volume: 163
Issue: 8
Pages: 4328-34
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Publication
12097399 | J:123835
First Author: Villegas EN
Year: 2002
Journal: J Immunol
Title: A role for inducible costimulator protein in the CD28- independent mechanism of resistance to Toxoplasma gondii.
Volume: 169
Issue: 2
Pages: 937-43
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Publication
15689402 | J:110055
First Author: Singbartl K
Year: 2005
Journal: J Am Soc Nephrol
Title: T cells modulate neutrophil-dependent acute renal failure during endotoxemia: critical role for CD28.
Volume: 16
Issue: 3
Pages: 720-8
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Publication
15314039 | J:93659
First Author: Gao JX
Year: 2004
Journal: Int Immunol
Title: A new role for CD28 in the survival of autoreactive T cells in the periphery after chronic exposure to autoantigen.
Volume: 16
Issue: 10
Pages: 1403-9
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Publication
10880526 | J:63142
First Author: Kopf M
Year: 2000
Journal: J Exp Med
Title: Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection.
Volume: 192
Issue: 1
Pages: 53-61
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Publication
18056348 | J:155039
First Author: Iliopoulou BP
Year: 2007
Journal: J Immunol
Title: CD28 deficiency exacerbates joint inflammation upon Borrelia burgdorferi infection, resulting in the development of chronic Lyme arthritis.
Volume: 179
Issue: 12
Pages: 8076-82
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Publication
7790813 | J:26220
First Author: Sperling AI
Year: 1995
Journal: J Exp Med
Title: CD43 is a murine T cell costimulatory receptor that functions independently of CD28.
Volume: 182
Issue: 1
Pages: 139-46
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Publication
17215523 | J:121853
First Author: Raué HP
Year: 2007
Journal: J Leukoc Biol
Title: Pivotal advance: CTLA-4+ T cells exhibit normal antiviral functions during acute viral infection.
Volume: 81
Issue: 5
Pages: 1165-75
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Publication
27460989 | J:260551
First Author: Dobbins J
Year: 2016
Journal: Sci Signal
Title: Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.
Volume: 9
Issue: 438
Pages: ra75
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Publication
9144484 | J:110667
First Author: Vella AT
Year: 1997
Journal: J Immunol
Title: CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.
Volume: 158
Issue: 10
Pages: 4714-20
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Publication
15634900 | J:95837
First Author: Elias RM
Year: 2005
Journal: J Immunol
Title: Role of CD28 in polyclonal and specific T and B cell responses required for protection against blood stage malaria.
Volume: 174
Issue: 2
Pages: 790-9
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Publication
8648099 | J:110668
First Author: Ferguson SE
Year: 1996
Journal: J Immunol
Title: CD28 is required for germinal center formation.
Volume: 156
Issue: 12
Pages: 4576-81
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Publication
9126966 | J:110674
First Author: Gause WC
Year: 1997
Journal: J Immunol
Title: CD28 dependence of T cell differentiation to IL-4 production varies with the particular type 2 immune response.
Volume: 158
Issue: 9
Pages: 4082-7
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Publication
12672399 | J:82789
First Author: Chapoval SP
Year: 2003
Journal: Clin Immunol
Title: CD28 costimulation is critical for experimental allergic asthma in HLA-DQ8 transgenic mice.
Volume: 106
Issue: 2
Pages: 83-94
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Publication
8676089 | J:110685
First Author: Saha B
Year: 1996
Journal: J Exp Med
Title: Protection against lethal toxic shock by targeted disruption of the CD28 gene.
Volume: 183
Issue: 6
Pages: 2675-80
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Publication
11329056 | J:69096
First Author: Maier S
Year: 2001
Journal: Nat Med
Title: Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice.
Volume: 7
Issue: 5
Pages: 557-62
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Publication
15135297 | J:89576
First Author: Cawthon AG
Year: 2004
Journal: Cell Immunol
Title: High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation.
Volume: 227
Issue: 2
Pages: 148-55
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7534617 | J:189425
First Author: Green JM
Year: 1994
Journal: Immunity
Title: Absence of B7-dependent responses in CD28-deficient mice.
Volume: 1
Issue: 6
Pages: 501-8
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10502560 | J:59459
First Author: Mathur M
Year: 1999
Journal: Am J Respir Cell Mol Biol
Title: CD28 interactions with either CD80 or CD86 are sufficient to induce allergic airway inflammation in mice.
Volume: 21
Issue: 4
Pages: 498-509
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Publication
16600196 | J:108140
First Author: Fukada K
Year: 2005
Journal: Cell Immunol
Title: CD28 is required for induction and maintenance of immunological memory in toxin-reactive CD4+ T cells in vivo.
Volume: 238
Issue: 2
Pages: 103-12
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Publication
11489978 | J:120414
First Author: Okazaki T
Year: 2001
Journal: J Immunol
Title: Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice.
Volume: 167
Issue: 4
Pages: 1977-81
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Publication
11120807 | J:118398
First Author: Wu ZQ
Year: 2000
Journal: J Immunol
Title: B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae.
Volume: 165
Issue: 12
Pages: 6840-8
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Publication
31565151 | J:293126
 
First Author: Liu Y
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD28 Deficiency Ameliorates Blast Exposure-Induced Lung Inflammation, Oxidative Stress, Apoptosis, and T Cell Accumulation in the Lungs via the PI3K/Akt/FoxO1 Signaling Pathway.
Volume: 2019
Pages: 4848560
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Publication
16311599 | J:129176
First Author: Tang Q
Year: 2006
Journal: Nat Immunol
Title: Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice.
Volume: 7
Issue: 1
Pages: 83-92
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Publication
24048955 | J:203113
First Author: Ogawa S
Year: 2013
Journal: Int Immunol
Title: CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.
Volume: 25
Issue: 12
Pages: 671-81
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Publication
10878386 | J:120495
First Author: Flaño E
Year: 2000
Journal: J Immunol
Title: Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages.
Volume: 165
Issue: 2
Pages: 1074-81
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Allele
Il2rb<tm1Mak> | MGI:1857193
Name: interleukin 2 receptor, beta chain; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Irf1<tm1Mak> | MGI:1857205
Name: interferon regulatory factor 1; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lck<tm1Mak> | MGI:1857211
Name: lymphocyte protein tyrosine kinase; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pten<tm1Mak> | MGI:1857937
Name: phosphatase and tensin homolog; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Msh2<tm1Mak> | MGI:1857940
Name: mutS homolog 2; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Smad4<tm1Mak> | MGI:1858049
Name: SMAD family member 4; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Brca1<tm1Mak> | MGI:1858108
Name: breast cancer 1, early onset; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Traf6<tm1Mak> | MGI:1859953
Name: TNF receptor-associated factor 6; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Bcl10<tm1Mak> | MGI:2158304
Name: B cell leukemia/lymphoma 10; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Casp9<tm1Mak> | MGI:2158754
Name: caspase 9; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Irf2<tm1Mak> | MGI:2175949
Name: interferon regulatory factor 2; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Casp3<tm1Mak> | MGI:2178778
Name: caspase 3; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Traf2<tm1Mak> | MGI:2179513
Name: TNF receptor-associated factor 2; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ctla4<tm1Mak> | MGI:2180669
Name: cytotoxic T-lymphocyte-associated protein 4; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Itgal<tm1Mak> | MGI:2181378
Name: integrin alpha L; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd44<tm1Mak> | MGI:2181292
Name: CD44 antigen; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pten<tm2Mak> | MGI:2182005
Name: phosphatase and tensin homolog; targeted mutation 2, Tak W Mak
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Diablo<tm1Mak> | MGI:2183277
Name: diablo, IAP-binding mitochondrial protein; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tsg101<tm1Mak> | MGI:2385839
Name: tumor susceptibility gene 101; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ikbkg<tm1Mak> | MGI:2386267
Name: inhibitor of kappaB kinase gamma; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Chek2<tm1Mak> | MGI:2386905
Name: checkpoint kinase 2; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Irf4<tm1Mak> | MGI:2387941
Name: interferon regulatory factor 4; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Icos<tm1Mak> | MGI:2445839
Name: inducible T cell co-stimulator; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Icosl<tm1Mak> | MGI:2669961
Name: icos ligand; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:4437928 | C.129P2-Cd276<tm1Mak>
Attribute String: mutant strain, targeted mutation, congenic
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Allele
Il27ra<tm1Mak> | MGI:3040914
Name: interleukin 27 receptor, alpha; targeted mutation 1, Tak Mak
Allele Type: Targeted
Attribute String: Null/knockout
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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